Clinical trials: Respiratory Failure, completed
Nasal Congestion
Efficacy and Safety of Azeol Nasal Spray Versus Placebo in the Treatment of Early Symptoms of Common Cold in Adults
The main objective is to evaluate the efficacy of Azéol Spray Nasal, taken two times a day, versus placebo on nasal congestion in subject with common cold.
- Trial name
- EXSPRAY (NCT05159271)
- Testing
- Azeol spray nasal
- Where
- 2 sites in France
- Volunteers
- 144 people
- Sponsor
- Larena SAS
Hypoxia, Respiratory Failure With Hypoxia
Finger Pulse Oximeters in Hosptial Setting
Pulse oximetry is a well-established, non-invasive measurement tool used to estimate arterial oxygen saturation. The accuracy of these cheap, readily available finger pulse oximeters has not been robustly assessed in a clinical…
- Trial name
- NCT06994663
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Dyspnea, Respiratory Insufficiency
Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness in Patients With Advanced Disease
Episodic breathlessness is a common and distressing symptom in patients with advanced disease such as cancer, chronic obstructive pulmonary disease (COPD) and chronic heart failure.
- Conditions
- Dyspnea, Respiratory Insufficiency, Neoplasms, Pulmonary Disease, Chronic Obstructive
- Trial name
- CoBeMEB (NCT04630743)
- Testing
- Cognitive and Behavioral intervention for the Management of Episodic Breathlessness
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Cologne
COVID-19, Respiratory Failure
Comparative Study of Anaconda System Use Versus Conventional Sedation in COVID-19 Patients.
At the beginning of 2020, a global alert emerged which saturated intensive care units due to COVID-19 worldwide. This caused a need for mechanical ventilation due to atypical pneumonias that had a rapid evolution and respiratory…
- Trial name
- NCT06208592
- Testing
- Sevoflurane with AnaConDa
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- Hospital Español de Mexico
Fall Patients, Pain
Physiotherapy in Emergency Department: a Service Analysis From a French Hospital
The skills of physiotherapists have been employed to enhance access to optimal care in Emergency Departments (ED). No study has yet been conducted on the practices in France.
- Conditions
- Fall Patients, Pain, Sprains, Respiratory Insufficiency
- Trial name
- NCT06528899
- Testing
- Physical Therapy
- Where
- 2 sites in France
- Volunteers
- 461 people
- Sponsor
- Université de Nantes
Cardiac Surgery
Risk of Oxygen During Cardiac Surgery Trial
The investigators will recruit and randomize 200 elective cardiac surgery patients to receive physiologic oxygenation (normoxia) or hyper-oxygenation (hyperoxia) during surgery to test the hypothesis that intraoperative…
- Trial name
- ROCS (NCT02361944)
- Testing
- Oxygen - normoxia, Oxygen - hyperoxia
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Vanderbilt University
Hantavirus Pulmonary Infection, Immunisation
Andes Virus DNA Vaccine for the Prevention of Hantavirus Pulmonary Syndrome Using the PharmaJet Stratis(R) Needle-Free Injection Delivery Device
This is a Phase 1, randomized, placebo controlled, double-blind, dose escalation trial of 48 males and non-pregnant females, 18-49 years old, inclusive, who are in good health and meet all eligibility criteria.
- Trial name
- NCT03682107
- Testing
- Andes virus DNA vaccine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acute Respiratory Failure
Non-rebreather at Flush Rate Compared to Bag Valve Mask With Assist
This crossover investigation enrolls healthy volunteers and compares the exhaled oxygen content (FeO2) between the non-rebreather mask at the flush rate and a bag-valve-mask device at the flush rate, used with active positive…
- Trial name
- NCT02841592
- Testing
- Flush rate oxygen, Flush rate oxygen with assist
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Chronic Heart Failure, Central Sleep Apnea
French Cohort Study of Chronic Heart Failure Patients With Central Sleep Apnoea Eligible for Adaptive Servo-Ventilation (PaceWave, AutoSet CS)
The purpose of FACE study is to provide in routine practice complementary long-term data on the mortality and morbidity of Chronic Heart Failure (CHF) patients with Central Sleep Apnea eligible for Adaptative Servo-Ventilation…
- Trial name
- FACE (NCT01831128)
- Testing
- ASV Treatment
- Where
- 18 sites in France
- Volunteers
- 509 people
- Sponsor
- ResMed
Respiratory Insufficiency
"TRAcheostomy With Single Use Bronchoscopes vs. Conventional Bronchoscopes"
Optical guidance for percutaneous tracheostomy in intensive care is usually performed by conventional multi use bronchoscopy. Recently a single use bronchoscope has been introduced that allows for endotracheal visualization.
- Trial name
- TraSUB (NCT03952247)
- Testing
- Single Use Bronchoscopy for PDT, Conventional Multi Use Bronchoscopy for PDT
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Heart Failure
Inspiratory Muscular Training
Objectives: To evaluate regional lung ventilation distribution in patients suffering from chronic heart failure (CHF) after completing inspiratory muscle training (IMT) and correlate it with functional capacity and quality of…
- Trial name
- NCT01593007
- Testing
- Inspiratory muscle training, Control group
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Universidade Federal de Pernambuco
COVID19, Ophthalmopathy
Ocular Sequelae of Patients Hospitalized for Respiratory Failure During the COVID-19 Epidemic
Ophthalmologic damages secondary to COVID-19 coronavirus infection are little described. The ocular involvement is probably multiple, ranging from pathologies of the anterior segment such as conjunctivitis and anterior uveitis to…
- Trial name
- SOCOVID (NCT04387292)
- Testing
- Ophthalmologic exam
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Hypoxemic Acute Respiratory Failure
High Flow Nasal Oxygen Therapy for Hypoxemy After Cardiac Surgery
The main objective of this study is to evaluate the gas exchange (ventilation-perfusion ratio) with the system Optiflow® compared to facial mask among patients having an acute respiratory failure after cardiac surgery.
- Trial name
- Optiflow (NCT01617252)
- Testing
- Optiflow / Facial mask
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Nantes University Hospital
Respiratory Failure With Hypoxia, Respiratory Failure Without Hypercapnia
Prone Positioning During High Flow Oxygen Therapy in Acute Hypoxemic Respiratory Failure
Background High-flow nasal cannula (NHF) are a promising tool for administering oxygen to critically ill patients with high respiratory demand.
- Trial name
- Optiprone (NCT03095300)
- Testing
- Prone position
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Catholic University of the Sacred Heart
Chronic Respiratory Failure
Adaptation to Nocturnal Noninvasive Ventilation in Patients With Chronic Respiratory Failure (ROOMILA)
BACKGROUND: Adaptation to noninvasive ventilation (NIV) is a critical step for acceptability and efficacy of this treatment during sleep in patients with chronic respiratory failure.
- Trial name
- ROOMILA (NCT01255111)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Groupe de Recherche sur le Handicap Respiratoire
Nasal Obstruction
The Effect of Nasal Hair on Nasal Obstruction
Nasal obstruction is a common complaint prompting presentation to an otolaryngologist. Many studies have been performed quantifying and describing the impact of a number of factors on symptoms of nasal obstruction, including…
- Trial name
- NCT01850511
- Testing
- Vibrissae trimming, Application of oxymetazoline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diaphragmatic Paralysis
Interscalene Block and Dysfunction Diaphragmatic
The study seeks to show that interscalene injection of a small volume (<8ml) of ropivacaine at a low concentration (0.1%) reduces the frequency of hemi-diaphragmatic paresis compared to low volume injection at the standard…
- Trial name
- NUMEROBIS (NCT04173364)
- Testing
- Ropivacaine 0.5% Injectable Solution, Ropivacaine 0.1% Injectable Solution
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Lille
Pleural Effusion, Heart Failure
Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)
To assess the discriminative properties of pleural fluid (PF) N-terminal-proB-type-natriuretic-peptide (NTproBNP) levels in identifying heart failure (HF)-associated pleural effusions (PE).
- Conditions
- Pleural Effusion, Heart Failure, Malignant Neoplasm, Fluid Overload
- Trial name
- NCT05797649
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Chinese University of Hong Kong
Distress Respiratory Syndrome, Weaning Failure
Pressure Support Ventilation Versus Neurally Adjusted Ventilatory Assist in Difficult to Wean Pediatric Patients
This study assessed the effects of NAVA versus Pressure Support Ventilation (PSV) on patient-ventilator interaction in pediatric patients with difficult weaning from mechanical ventilation after moderate Pediatric Acute…
- Trial name
- NCT04360590
- Testing
- pressure support ventilation versus neurally adjusted ventilatory assist
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Respiratory Insufficiency, Hematologic Malignancy
Systematic Evaluation by an Intensivist of Hematological Malignancy Patients Presenting With Acute Respiratory or Hemodynamic Failure
Over the last two decades, the number of patients with hematological malignancies (HMs) admitted to the ICU increased and their mortality has dropped sharply.
- Trial name
- CAREHEMA (NCT03399149)
- Testing
- Systematic evaluation by an intensivist
- Where
- 2 sites in France
- Volunteers
- 221 people
- Sponsor
- University Hospital, Grenoble
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