Clinical trials: Respiratory Functions
Pulmonary Function
Influence of Tidal Volume on Postoperative Pulmonary Function
Lung function impairment is common after abdominal surgery. Few preventive strategies exist against postoperative lung function impairment.
- Trial name
- tidalvolume (NCT00795964)
- Testing
- Randomized application of intraoperative tidal volume
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
COVID-19, Long COVID-19
Effects of Physiotherapy Via Telerehabilitation in Patients With COVID-19
This study aims to evaluate the effects of Physiotherapy Via Video Calls on Cardiopulmonary Functions, Physical Function, Cognitive Function, Activity Daily Livings, and Quality of Life in Patients With COVID-19.
- Conditions
- COVID-19, Long COVID-19, Cardiopulmonary Function, Physical Function
- Trial name
- NCT06251011
- Testing
- Exercise training
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Chulabhorn Hospital
Complication,Postoperative, Lung Cancer
Relationship Between Hand Dynamometer Measurements, PFT, and mFI With Postoperative Outcomes
The study will take place at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital and will include 100 patients over the age of 40 who are scheduled for lung malignancy surgery after 01 April 2024.
- Trial name
- NCT06338007
- Testing
- Hand Dynamometer, Pulmonary Function Test, Modified Frailty Index
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Covid19
Balance Function in Patients Post Corona Virus Disease 2019 (COVID-19)
The purpose of this study is to describe balance deficits in patients post COVID-19. The information the investigators learn may help influence balance training exercises for patients post-COVID-19.
- Trial name
- NCT04914364
- Testing
- Balance assessments
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Duke University
Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Efficacy and Safety of Umeclidinium Bromide/Vilanterol Compared With Fluticasone Propionate/Salmeterol Over 12 Weeks in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
This is a multicenter, randomized, double-blind, double-dummy, parallel group study. The purpose of this study is to compare the efficacy and safety of umeclidinium/vilanterol (UMEC/VI) and fluticasone propionate/salmeterol (FSC)…
- Trial name
- NCT01822899
- Testing
- Umeclidinium bromide/Vilanterol, Fluticasone propionate/Salmeterol
- Where
- 78 sites in Czechia, Denmark and 6 more
- Volunteers
- 717 people
- Sponsor
- GlaxoSmithKline
Respiratory Physiological Phenomena
Functional Residual Capacity Measured by Capnography in Ventilated Patients
Changes in body position during anesthesia can alter functional residual capacity and gas exchange. The monitoring of such changes in functional residual capacity is difficult at the bedside.
- Trial name
- NCT03693352
- Where
- Argentina
- Volunteers
- 40 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Paranasal Sinus Disease
Effectiveness of Antibiotic Delivery Via Bio-absorbable Sponge
This study will evaluate the efficacy of a nasopore sponge dressing soaked in Bacitracin VS a sponge soaked in Saline / and the administration of oral antibiotics.
- Trial name
- NCT01222832
- Testing
- Bacitracin
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Mechanical Ventilation Complication, Pulmonary Edema
Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)
The purpose of this study is to determine if the left and right ventricular systolic function is involved in the development of weaning failure related to weaning-induced pulmonary edema.
- Trial name
- SystoWean (NCT05226247)
- Testing
- Spontaneous breathing trial
- Where
- 3 sites in France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Diagnosing Obstructive Lung Disease With Point of Care Ultrasound
The objective of this study is to evaluate the diagnostic accuracy of Point of Care Ultrasound (POCUS) in identifying obstructive lung diseases (OLDs), using pulmonary function tests (PFTs) as the gold standard for comparison.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Asthma, COPD
- Trial name
- NCT06251271
- Testing
- Point-of-Care Ultrasound
- Where
- Israel
- Volunteers
- 301 people
- Sponsor
- Soroka University Medical Center
Respiratory Distress Syndrome, Adult, Critical Illness
Measuring Heart and Lung Function in Critical Care
This is a feasibility study of the use of a novel technique called 'Inspiwave' to measure heart and lung function in adult patients in critical care.
- Conditions
- Respiratory Distress Syndrome, Adult, Critical Illness, Mechanical Ventilation Complication, Haemodynamic Instability
- Trial name
- NCT03424798
- Testing
- Inspiwave
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Oxford
Cystic Fibrosis
The Prevalence and Significance of Gastro-oesophageal Reflux in Cystic Fibrosis Before and After Lung Transplantation
Gastro-oesophageal reflux (GOR) has been found to be prevalent in children with cystic fibrosis (CF)and may further worsen lung damage via reflex bronchospasm or pulmonary aspiration.
- Trial name
- NCT00164021
- Testing
- Physiotherapy, exercise, percutaneous gastrostomy feeds, Anti-reflux pharmacotherapy
- Where
- Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Cystic Fibrosis, Constipation
Effect of Lubiprostone on Nutritional Status and Pulmonary Function in Adults With Cystic Fibrosis
Cystic fibrosis (CF) results in thickened secretions in multiple organ systems including the lungs and gastrointestinal (GI) tract.
- Conditions
- Cystic Fibrosis, Constipation, Nutrition
- Trial name
- NCT00577499
- Volunteers
- 7 people
- Sponsor
- University of Arkansas
Neurocognitive Disorders, Inhalation; Vapor
Effect of Low Flow Anesthetics on Neurocognitive Decline in the Elderly
This study aims to investigate the effect of inhaled anesthetics with a low fresh gas flow on cognitive function of elderly patients undergoing elective surgery
- Trial name
- NCT05548998
- Testing
- General anesthesia with low fresh gas flow, General anesthesia with high fresh gas flow, Mini mental state examination
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Cystic Fibrosis
Muscle Accrual and Function in Cystic Fibrosis-Impact of Glucose Intolerance
This study will investigate the link between glucose abnormalities and elements critical to muscle function including mass, composition and energy metabolism.
- Trial name
- NCT02776098
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Stroke
Respiratory Functions and Muscle Strength, Trunk Control, Functional Capacity and Independence in Hemiplegic Patients
The aim of this study was to invastigate the relationship between respiratory functions and respiratory muscle strength with trunk control, functional capacity and functional independence in hemiplegic patients after stroke.
- Trial name
- NCT05290649
- Testing
- clinical assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Halic University
Forward Head Posture
Effects of Nordic Pole Walking in Adults With Forward Head Posture
This randomized controlled trial aims to investigate the effects of Nordic pole walking on pain, neck-related disability, pulmonary function, respiratory muscle strength, and postural alignment in adults with forward head posture…
- Trial name
- NCT07840755
- Testing
- Nordic Pole Walking, General Walking
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Sahmyook University
COVID 19
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ALG-097558 in Subjects With Renal Impairment and in Healthy Subjects With Normal Renal Function
This is a Phase 1 non-randomized, open-label, multiple dose, parallel-group study of ALG-097558 in subjects with severe renal impairment and subjects without renal impairment, matched for age, body weight and, to the extent…
- Trial name
- NCT06698549
- Testing
- ALG-097558
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aligos Therapeutics
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI)
CPAP Randomized Controlled Trial
The overall goal of this randomized controlled trial is to test the hypothesis that in older adults with mild cognitive impairment (MCI) and previously untreated obstructive sleep apnea (OSA), 4 months of web-based sleep…
- Conditions
- Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI), Cognitive Decline Prevention in Pre-frail Older Adults
- Trial name
- NCT06773416
- Testing
- CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health, Delayed CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health
- Where
- Canada
- Volunteers
- 206 people
- Sponsor
- Sunnybrook Health Sciences Centre
Covid19
Hyperpolarized 129Xe MRI of Survivors of COVID-19
The purpose of this study is to evaluate pulmonary function of patients recovering from mild, moderate, and severe COVID-19 disease using hyperpolarized 129Xe MRI.
- Trial name
- NCT04659707
- Testing
- Hyperpolarized Xe129
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Kansas Medical Center
Parkinson Disease, Parkinsonism
Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD
Parkinsonism impairs upper airway and axial motor control, leading to disordered breathing, reduced speech volume, and ineffective cough. Symptoms are poorly addressed by current therapies.
- Trial name
- NCT07674264
- Testing
- Acute intermittent hypercapnic hypoxia (AIHH), Acute intermittent hypercapnic normoxia (AIHN)
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Florida
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