Clinical trials: Respiratory Hygiene
Mechanical Ventilation, Infection Prevention
Oral Care Layered Enhancement for Improved Oral Hygiene in Intensive Care Units
The goal of the ORACLE study is to evaluate the impact of implementing a standardized oral hygiene bundle on outcomes in critically ill, mechanically ventilated patients.
- Conditions
- Mechanical Ventilation, Infection Prevention, Oral Care, Oral Hygiene, Oral Health
- Trial name
- ORACLE (NCT07129733)
- Testing
- Oral hygiene bundle
- Where
- 6 sites in Brazil
- Volunteers
- 4,800 people
- Sponsor
- Hospital do Coracao
Acute Respiratory Tract Infections, Respiratory Infection Prevention
Effectiveness of Education on Preventive Measures Against Acute Respiratory Tract Infections in School-Age Children
This study aimed to evaluate the effectiveness of an animation video-supported education program on preventive measures against acute respiratory tract infections among first-grade primary school children.
- Conditions
- Acute Respiratory Tract Infections, Respiratory Infection Prevention, Hand Hygiene, Respiratory Hygiene
- Trial name
- NCT07654712
- Testing
- Animation Video-Supported Education on Preventive Measures Against Acute Respiratory Tract Infections
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Diarrhea, Respiratory Tract Infections
The Impact of a School-based WASH Intervention on Child Health and School Attendance in Addis Ababa, Ethiopia
This study aims to assess the effects of school-based, comprehensive water, sanitation, and hygiene improvements on child health and educational outcomes in schools in Addis Ababa, Ethiopia.
- Conditions
- Diarrhea, Respiratory Tract Infections, Absenteeism
- Trial name
- WISE (NCT05024890)
- Testing
- Splash WASH in Schools programme (Project WISE)
- Where
- Ethiopia
- Volunteers
- 7,072 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Neurologic Disorder, Respiratory Complication
Chest Therapy and Postural Education in Children With Cerebral Palsy
INTRODUCTION: Neurological Chronic disease leads to motor disability and associated pathologies. Numerous studies agree that the lack of prevention and treatment in pulmonary health in children with disabilities results in…
- Conditions
- Neurologic Disorder, Respiratory Complication, Child
- Trial name
- NCT03946137
- Testing
- Chest Therapy, Postural Hygiene
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Bacterial Transmission, Intubation Intratracheal
ORAL-PROTECT I: Oral Asepsis Preventing Transmission During Intubation
Postoperative respiratory complications, such as bacterial pneumonia, are common and serious problems after general anesthesia. They can lead to longer hospital stays, more complications, and increased mortality.
- Conditions
- Bacterial Transmission, Intubation Intratracheal, Chlorhexidine
- Trial name
- ORAL-PROTECT I (NCT07669064)
- Testing
- Preoperative oral decontamination with chlorhexidine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Ulm
Nasal Hygiene, Respiratory Tract Infection Prevention
Effectiveness of Play-Based Nasal Hygiene Education in Preschool Children
This study aimed to determine the effectiveness of a play-based nasal hygiene education program on nasal hygiene knowledge and skills among preschool children.
- Conditions
- Nasal Hygiene, Respiratory Tract Infection Prevention, Health Behavior, Preschool Children
- Trial name
- NCT07654673
- Testing
- Play-Based Nasal Hygiene Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Gingivitis; Chronic
Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis
This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and…
- Trial name
- NCT07689786
- Testing
- Miswak, Toothpaste
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Helminthiasis, Diarrhea
Spillover Effects of Water, Sanitation, and Hygiene Interventions on Child Health
The purpose of this study is to measure whether a combined water, sanitation, and hygiene intervention leads to improved health of children who did not receive the intervention themselves and who live within a close vicinity of…
- Conditions
- Helminthiasis, Diarrhea, Respiratory Infection
- Trial name
- NCT02396407
- Testing
- Combined water, sanitation, and hygiene
- Where
- Bangladesh
- Volunteers
- 1,789 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Healthy Participants
Educational VR Game Intervention to Enhance Hygiene Practices in Primary School Children
The goal of this observational study is to investigate if VR game-based educational intervention can enhance primary schoolchildren's compliance with hygiene practices to prevent the transmission of SARS-CoV-2 and other upper…
- Trial name
- NCT07168759
- Testing
- VR game -based education program
- Where
- China
- Volunteers
- 2,160 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Ventilator Associated Pneumonia, Oral Hygiene
Implementation and Evaluation of Revised Protocols for Oral Hygiene for Mechanically Ventilated Patients
The primary objective of this study is to evaluate the effectiveness and feasibility of the implementation of revised standards of care for oral hygiene (SAGE Q-care q2 Oral Cleansing and Suctioning System with and without…
- Trial name
- NCT01657396
- Testing
- Standard Oral Hygiene, SAGE Q-care q2, SAGE Q-care q2 with Chlorhexidine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Calgary
Tracheal and Oropharyngeal Colonization by Gram-negative Pathogens
Oral Care and Gram-negative Pathogen in Children
Critical care nursing interventions related to oral care can reduce the microorganisms in the oropharynx available for translocation to other sites.
- Trial name
- NCT01410682
- Testing
- 0,12% digluconate chlorhexidine, toothbrushing
- Volunteers
- 74 people
- Sponsor
- Federal University of São Paulo
Ventilator-Associated Pneumonia
The Effect of Solutions Used in Oral Care on Preventing Ventilator-Associated Pneumonia.
The goal of this clinical trial is to learn about effects of chlorhexidine gluconate, sodium bicarbonate, ozonated water and hypochlorous acid solutions used in oral care of patients on mechanical ventilation support on…
- Trial name
- NCT06118242
- Testing
- Use of oral care solutions
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Aydin Adnan Menderes University
Periodontitis, Gingivitis
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : improved dental health reduced risk of pneumonia better glucose…
- Conditions
- Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections
- Trial name
- NHOralHealth (NCT06890676)
- Testing
- Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Missouri Department of Health and Senior Services
Gingivitis; Chronic
The Effect of Probiotics on Gingivitis: Part 2
The aim of the study is to assess the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene in young adults.
- Trial name
- NCT05919134
- Testing
- Dentoblis
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Stroke, Aspiration Pneumonia
Effect of Oral Hygiene Care on Prevention of Aspiration Pneumonia Among Hospitalized Stroke Patients
Aspiration pneumonia is a common and serious complication among hospitalized patients with stroke. Poor oral hygiene can increase the risk of aspiration pneumonia by promoting bacterial colonization of the oral cavity.
- Trial name
- OH-STROKE (NCT07382089)
- Testing
- Oral hygiene care bundle
- Where
- Ethiopia
- Volunteers
- 90 people
- Sponsor
- Addis Ababa University
Gingivitis and Periodontal Diseases, Gingivitis; Chronic
Guided Biofilm Therapy Compared to Traditional Cleaning for Treating Gingival Inflammation in Orthodontic Patients
Why is this study being done? This study is for people with braces who have gum inflammation (gingivitis), which is when gums are swollen and bleed easily.
- Conditions
- Gingivitis and Periodontal Diseases, Gingivitis; Chronic, Gingivitis, Gingival Bleeding
- Trial name
- NCT07355517
- Testing
- Guided Biofilm Therapy, Traditional Ultrasonic Scaling + Polishing
- Where
- Jordan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Covid19
Home-based Care and Hand Hygiene Interventions in Honduras
This study aims to enroll patients with acute infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) who do not meet criteria for hospital admission according to protocols developed by the Honduras Ministry…
- Trial name
- NCT04886414
- Testing
- Phone-based monitoring, Oxygen saturation monitoring, Alcohol-based hand sanitizer
- Where
- Honduras
- Volunteers
- 1,821 people
- Sponsor
- Brigham and Women's Hospital
Pneumonia
Oral Care Protocol for Preventing Ventilator- Associated Pneumonia
The Nosocomial Pneumonia remains to be a major complication for patients who were incubated with ventilation. Most cases are attributed to increased bacteria flora in oropharyngeal secretion and aspiration of those organisms.
- Trial name
- VAP (NCT00604916)
- Testing
- standardized oral care protocol - electronic toothbrush, mimic protocol
- Volunteers
- 53 people
- Sponsor
- Mackay Memorial Hospital
Healthcare-Associated Pneumonia
Hospital-acquired Pneumonia Prevention: Intervention, Evaluation & Research
The purpose of this study is to determine the effectiveness of a universal, standardized oral care protocol on prevention of non-ventilated hospital-acquired pneumonia (NV-HAP) in the acute care setting.
- Trial name
- HAPPIER-1 (NCT04915898)
- Testing
- Oral Hygiene - teeth brushing
- Where
- United States
- Volunteers
- 8,709 people
- Sponsor
- Orlando Health, Inc.
Severe Influenza, Intensive Care (ICU)
Early Corticosteroids in Severe Influenza Pneumonia
This is a Phase III, multicentre, randomized, controlled, double-blind, superiority trial aiming to evaluate the efficacy of dexamethasone versus placebo in patients admitted to intensive care or intermediate care with influenza…
- Conditions
- Severe Influenza, Intensive Care (ICU), Reanimation, Infectious Diseases
- Trial name
- ECSIP (NCT07786662)
- Testing
- Dexametasone
- Where
- 48 sites in France
- Volunteers
- 544 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville