Clinical trials: Respiratory Loading
Shortness of Breath, Shortness of Breath/Dyspnea
Training Strategies to Maintain Performance
Statement of the Problem and Justification Cognitive performance under physiologically stressful conditions is critical in high-demand environments such as military operations, diving, and firefighting.
- Conditions
- Shortness of Breath, Shortness of Breath/Dyspnea, Respiratory Distress
- Trial name
- NCT07128511
- Testing
- Multiple Inhalation Breathing Pattern, Tactical Breathing Technique
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Florida
Athletic Performance
Influence of Respiratory Muscle Training on Objective and Subjective Training Load Measures in Triathletes
Two groups of healthy, highly trained triathletes trained respiratory muscles with one of the two methods: voluntary isocapnic hyperpnoea (VIH) or inspiratory pressure threshold loading (IPTL).
- Trial name
- NCT05936398
- Testing
- Respiratory Muscle Training - VIH, Respiratory Muscle Training - ITPL
- Where
- Poland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Institute of Sport - National Research Institute, Poland
Sars-CoV-2 Infection
Viral Load Analysis of the SARS-CoV-2 Virus in Nose Versus Mouth Sites
It is a single-center, non-profit experimental study, intended to evaluate the viral load of SARS COV 2 in nasal and oral samples of positive subjects to evaluate any variation and understand which is the most suitable site for…
- Trial name
- NCT05769803
- Testing
- Nasal and mouth swab
- Where
- Italy
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Healthy Adult Male
Wearable Resistance Vest for Strengthening Respiratory Muscles
Respiratory muscle weakness significantly limits functional capacity in various populations, yet conventional respiratory muscle training (RMT) often requires coached, mouthpiece-based maneuvers that may be limited by technique…
- Trial name
- WEARVEST (NCT07698873)
- Testing
- Wearable Resistance Vest
- Where
- Saudi Arabia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
COVID-19, SARS-CoV-2 Infection
Assessment of the Impact of Oral Intervention With Cetylpyridinium Chloride to Decrease SARS-CoV-2 Viral Load in Patients With COVID-19
Pilot, randomized and controlled clinical trial for the evaluation of the decrease in the viral load of SARS-CoV-2 in the oropharynx in patients with COVID-19 through the use of mouthwash containing cetylpyridinium chloride (CPC)…
- Trial name
- NCT04820803
- Testing
- ORAL INTERVENTION WITH CETYLPYRIDINIUM CHLORIDE
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rosa Tarrago
Stress, Burnout
RECHARGE: A Brief Psychological Intervention to Build Resilience in Healthcare Workers During COVID-19
The healthcare industry is inherently demanding, stressful, and, at times, emotionally draining. On a typical day, many workers must make rapid and critical decisions, manage numerous demands, team conflicts, and challenging…
- Conditions
- Stress, Burnout, Anxiety, Depression
- Trial name
- NCT04531774
- Testing
- RECHARGE, Self Study
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Naser Morina
Sedentary Lifestyle in Patients Over 70
Effect of PEP'C-R on Endurance Parameters and Maximal Cardio-respiratory Function Among Sedentary Older Seniors Over 70
The primary purpose of the protocol is to determine the effects of a new program of PEP'C "PEP'C with constant load and intermittent recovery" (PEP'C-R) on endurance parameters of older seniors.
- Trial name
- PEP'C-R (NCT02263573)
- Testing
- PEP'C-R, Control group usual activities
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Dyspnea
Specificity of Dyspnoea Relief With Inhaled Furosemide
This study evaluates the effect of inhaled furosemide on different types of breathlessness relief in healthy volunteers. Each volunteer inhaled mists of either furosemide or a control substance on 3 occasions per day on 2…
- Trial name
- FurosAH (NCT02881866)
- Testing
- Furosemide, Saline
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Healthy
Non-invasive Neurally Adjusted Ventilatory Assist in Healthy Volunteers
Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assistance to spontaneous breathing based on the detection of the electrical activity of the diaphragm.
- Trial name
- NCT00941044
- Testing
- Neurally adjusted ventilatory assist
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pregnancy, Respiratory Aspiration of Gastric Contents
Gastric Emptying Following an Oral Carbohydrate Load in Women Admitted for Elective Cesarean Delivery
Because of the risk of pulmonary aspiration, patients are asked to comply with the fasting guidelines when they are scheduled for an elective cesarean section.
- Trial name
- NCT03593980
- Testing
- Cranberry juice
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Accessory Muscle
Activation Patterns of Respiratory Muscles to Loaded Inspiratory Muscle Tests in Healthy Adults Under Different Posture
Whether minimizing sternocleidomastoid (SCM) activation in supine position would increase diaphragm activation during loaded inspiratory muscle tests remains to be determined.
- Trial name
- NCT03729986
- Testing
- Loaded inspiratory muscle test
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Inadequate or Impaired Respiratory Function
Positive Airway Pressure Versus Breathing Exercises With Load Inspiratory in Patients Undergoing Bariatric Surgery
Obesity, due to excess fat in the thoracoabdominal region, can promote changes in respiratory function and lung function, leading to reduction in lung volume and capacity.
- Trial name
- NCT02682771
- Testing
- Bilevel positive airway pressure, PowerBreathe, Conventional Respiratory Physiotherapy (CRP)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
COVID-19
The Role of Chlorhexidine in Minimizing the Viral Load Among COVID-19 Patients
Existing evidence confirmed that saliva and oral cavity to be a reservoir for SARS-CoV-2. In dental clinic aerosol-producing-procedures pose a significant risk for transmission of the infection .
- Trial name
- NCT04941131
- Testing
- Chlorhexidine digluconate, povidone iodine
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Pulmonary Atelectasis, Respiratory Tract Diseases
Application Breathing Exercises With Load Inspiratory Postoperative Abdominal Surgery
The aim of this study is to evaluate the effects of the use of breathing exercises with inspiratory loading on respiratory muscle strength and endurance, lung volumes and capacities and thoracoabdominal mobility in patients after…
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT02298517
- Testing
- incentive spirometry, inspiratory load equipment
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Occupational Exposure
Effects of a 60-min Repeated Trunk Flexion Protocol on Trunk Neuromuscular Properties.
An interventional study on the effects of repeated trunk flexion exposure on trunk neuromuscular properties.
- Trial name
- NCT05511896
- Testing
- Repeated trunk flexion
- Where
- Slovenia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Chronic Obstructive Pulmonary Disease (COPD)
Postural Control in Chronic Obstructive Pulmonary Disease
Postural control impairment is common in people with COPD (pwCOPD), which can increase the risk of falls and affect quality of life.
- Trial name
- NEUROTIGUE P (NCT06863246)
- Testing
- Evaluation of cognitive task on static balance, Evaluation of visual feedback on static balance
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
SARS-CoV-2, COVID-19
The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load
Preoperative antiseptic mouth rinses have been widely used as a standard protocol before routine dental treatment reduces oral microorganism counts.
- Conditions
- SARS-CoV-2, COVID-19, Mouthwashes, Viral Load
- Trial name
- NCT04721457
- Testing
- Distilled Water, 1% Povidone Iodine (PVP-I), 1.5% Hydrogen Peroxide (H2O2)
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Pulmonary Disease, Chronic Obstructive, Healthy
Low Load, High-repetitive Elastic Band Resistance Training in COPD
Recent work have shown that low load, high-repetitive single limb resistance training, if compared to a control, can increase limb muscle function and functional exercise capacity in patients with chronic obstructive pulmonary…
- Trial name
- NCT02283580
- Testing
- Single limb, Two limb
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laval University
Low Back Pain, Respiratory Loading
Inspiratory Resistive Loading and Proprioceptive Postural Control
Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance.
- Conditions
- Low Back Pain, Respiratory Loading, Proprioceptive Impairment
- Trial name
- NCT01541020
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy Subjects
Analysis of Breath Volatile Organic Compounds After Dyspnea Induced in the Healthy Subject.
The dyspnea is a common symptom in patients with many respiratory diseases particularly chronic obstructive airway diseases, but also cardiovascular pathologies, obesity, or also in the deconditioned healthy subjects.
- Trial name
- Volatopnee (NCT04418973)
- Testing
- VOCs analysis in exhaled air
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hopital Foch