Clinical trials: Respiratory Muscles, open to volunteers
Pompe Disease
Phrenic Nerve and Diaphragm Electrophysiology in Pompe Disease
Pompe disease is traditionally considered a lysosomal myopathy. However, increasing experimental and clinical evidence suggests involvement of the entire motor unit, including motor neurons, peripheral nerves, neuromuscular…
- Trial name
- NCT07664930
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Bronchiectasis, Functional Inspiratory Muscle Training
Functional Inspiratory Training in Bronchiectasis
Bronchiectasis is a chronic respiratory disease clinically characterized by recurrent pulmonary exacerbations, chronic cough, and sputum production, and is associated with an increase in the airway-artery ratio and permanent…
- Trial name
- NCT07188675
- Testing
- Functional Inspiratory Muscle Training (FIMT), Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Elif Kabasakal
Healthy
Effects of Respiratory Muscle Training on Tongue Muscle Function
This study aims to investigate the effects of respiratory muscle training on tongue muscle function in healthy subjects. We hypothesize that respiratory muscle training can improve strength and endurance of the tongue muscles.
- Trial name
- NCT06627283
- Testing
- IMT, EMT
- Where
- 3 sites in Belgium, Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Obesity and Obesity-related Medical Conditions, Diabetes
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research…
- Conditions
- Obesity and Obesity-related Medical Conditions, Diabetes, Atherosclerotic Disease, Heart Failure
- Trial name
- VALD (NCT07083557)
- Testing
- Endothelial cell collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bettina Mittendorfer
Sports Performance, Respiratory Muscle Function
Inspiratory Muscle Warm-Up in Combat Athletes
The aim of this study is to investigate the effects of inspiratory muscle warm-up (IMW) on technical performance and physiological responses in combat athletes.
- Conditions
- Sports Performance, Respiratory Muscle Function, Cardiorespiratory Responses
- Trial name
- NCT07481916
- Testing
- POWERbreathe
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Acute Spinal Cord Injury
The Use of Functional Electrical Stimulation in Conjunction With Respiratory Muscle Training to Improve Unaided Cough in Individuals With Acute Spinal Cord Injury
The overall objective of this study is to improve unaided cough with abdominal and latissimus dorsi functional electrical stimulation in conjunction with respiratory muscle training in individuals with acute spinal cord injuries.
- Trial name
- AFES and RMT (NCT05745298)
- Testing
- Xcite Clinical Station
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Chronic Obstructive Pulmonary Disease
Different Inspiratory Muscle Trainings in Patients With COPD
COPD is one of the most life-threatening pulmonary diseases. According to the World Health Organization, it is expected to rise to the third leading cause of death by 2030. Smoking is the most significant contributing factor.
- Trial name
- NCT07406659
- Testing
- Basic Inspiratory Muscle Training, Functional Inspiratory Muscle Training, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- University of Yalova
COPD (Chronic Obstructive Pulmonary Disease)
Digital High-Intensity Respiratory Muscle Training on COPD Patients
The goal of this Randomize control trail is to determine the effect of Digital High-Intensity Respiratory Muscle Training on ventilatory Function and Functional Capacity in Patients with COPD It will also learn about the safety…
- Trial name
- COPD (NCT07346261)
- Testing
- Digital Sonmol Respiratory Muscle Trainer, conventional respiratory rehabilitation
- Volunteers
- 60 people
- Sponsor
- Cairo University
COPD - Chronic Obstructive Pulmonary Disease, Forward Head Posture
Combined Posture Correction and Resistive Respiratory Muscles Training in COPD With FHP
Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation, often exacerbated by postural abnormalities such as forward head posture (FHP).
- Trial name
- NCT07293429
- Testing
- Resistive inspiratory muscles training, Resistive expiratory muscles training:, Combined resistive inspiratory and expiratory muscles training
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Respiratory Support
The ACCESSIT Study
The study is designed to characterize and monitor the structure, degree of activation and function of the different respiratory muscles during mechanical ventilation after spine trauma and spinal cord injury.
- Trial name
- ACCESSIT (NCT05207046)
- Testing
- Mechanical Ventilation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Burn
Impact of Inspiratory Muscle Training Post-Burn
Pulmonary dysfunction can be developed as a result of complications caused by direct thermal injury to the respiratory tract, smoke irritations, and respiratory tract infection.
- Trial name
- NCT07867639
- Testing
- Inspiratory muscle training, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Respiratory Function, Respiratory Muscle Strength
Respiratory Function and Athletic Performance in Professional Soccer Players
This prospective observational study aims to investigate the relationship between respiratory function and multidimensional athletic performance parameters in professional soccer players.
- Conditions
- Respiratory Function, Respiratory Muscle Strength, Athletic Performance, Reaction Time
- Trial name
- NCT07617116
- Testing
- Respiratory and Athletic Performance Assessments
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Istinye University
Ventilator Induced Diaphragm Dysfunction, Respiratory Muscle Weakness
Standardization of IMT Dosage (UTIT) in Mechanical Ventilation.
Respiratory muscle weakness prolongs mechanical ventilation (MV) and delays weaning. Currently, there is no standardized dosage for Inspiratory Muscle Training (IMT) in the ICU.
- Conditions
- Ventilator Induced Diaphragm Dysfunction, Respiratory Muscle Weakness, Mechanical Ventilation Weaning
- Trial name
- UTIT-IMT (NCT07761468)
- Testing
- Inspiratory Muscle Training (IMT)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital H+ Queretaro
Bronchial Congestion, Airway Clearance Impairment
Bronchial Clearance Carried Out With a Mechanical In-exsufflator vs. a Manual Respiratory Physiotherapy Technique in Hospitalized Elderly People
Everywhere in the world, life expectancy is increasing. Currently, most individuals can expect to live up to 60 years and beyond. In all countries, the number and proportion of older adult in the population are rising.
- Trial name
- INEXPA2 (NCT06730217)
- Testing
- Intervention : mechanical insufflator, Control : standard care
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Diabetes, Diabetes Mellitus
Investigation of Respiratory Muscle Sarcopenia in Adults Diagnosed With Diabetes
The aim of this study was to investigate respiratory muscle sarcopenia in individuals with diabet. The main question it aims to answer is: What is the prevalence of respiratory muscle sarcopenia in patients with diabet?…
- Conditions
- Diabetes, Diabetes Mellitus, Sarcopenia, Atrophy
- Trial name
- NCT07002333
- Volunteers
- 85 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Chronic Obstructive Pulmonary Disease (COPD)
The Prevalence of Lower Urinary Tract Symptoms in Individuals With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease characterized by airflow limitations and respiratory symptoms due to structural changes in the airways.
- Trial name
- NCT06958042
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kutahya Health Sciences University
Obesity, Class III, Sleep Apnea, Obstructive
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea
The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep…
- Conditions
- Obesity, Class III, Sleep Apnea, Obstructive, Inspiratory Muscle Training
- Trial name
- NCT07469280
- Testing
- High-Intensity Progressive Inspiratory Muscle Training (IMT)
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of the State of Santa Catarina
Cystic Fibrosis (CF)
Exercises' Effect on Muscle Strength, Aerobic Capacity and Respiratory Functions in Cystic Fibrosis
This research aims to evaluate the effects of upper and lower limb exercises on muscle strength and pulmonary function in children diagnosed with CF.
- Trial name
- NCT07508904
- Testing
- Arm Cycle Ergometry, Leg Cycle Ergometry
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Healthy Adults, Mechanical Ventilation Dependence
Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude
This study investigates whether respiratory muscle training (RMT) and dietary nitrate supplementation can improve exercise tolerance under simulated moderate altitude conditions.
- Conditions
- Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training
- Trial name
- NCT07216755
- Testing
- Respiratory Muscle Training (RMT), Dietary Supplement: Beetroot Juice Concentrate
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Embry-Riddle Aeronautical University
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis
We are studying the effect of a mind-body treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with or without Long COVID (LC).
- Trial name
- MILES (NCT06933173)
- Testing
- Dynamic neural retraining system
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta