Clinical trials: Respiratory Sounds
Sleep-disordered Breathing, Snoring
Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome
Upper airway obstruction (UAO) is an unrecognized source of hemodynamic stress that may contribute to aortic adverse events in persons with Marfan Syndrome (MFS).
- Trial name
- MSB (NCT03985657)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Asthma, Wheeze
Pediatric Arm of DZL All Age Asthma Cohort
Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood.
- Conditions
- Asthma, Wheeze, Hypersensitivity, Endophenotype
- Trial name
- ALLIANCE (NCT02496468)
- Where
- 5 sites in Germany
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Snoring
The Effect of Caffeine Reduction on Snoring and Quality of Life
Snoring is a problem for many people, often disturbing energy level, quality of sleep, and the relationship with a bed partner. Two observational studies that have indicated a relationship between the consumption of caffeine and…
- Trial name
- NCT00641810
- Testing
- Caffeine reduction
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Pneumothorax, Pulmonary Fibrosis
Computerized Lung Sound Analysis
This clinical trial is conducted within the research project 'Computerized Lung Sound Analysis'. The research goal is the development of a system enabling the automatic classification of lung sounds, which will result in a…
- Trial name
- CLSA (NCT02771184)
- Testing
- Lung Sound Recording System
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Smolle-Juettner Freyja, Prof MD
Respiration Disorders, Respiratory Disease
The Gut-Lung Axis and Respiratory Illness in Children
The goal of this single-centre observational study conducted at the Royal Hospital for Children in Glasgow, Scotland, is to employ a multi-omics approach to investigate the "gut-lung axis" in health and disease.
- Conditions
- Respiration Disorders, Respiratory Disease, Asthma in Children, Wheezing
- Trial name
- NCT06271213
- Testing
- observational only - no interventions as part of study
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Wheezing
A Phase 3 Trial of the Effect of Motavizumab Prophylaxis on Reduction of Serious Early Childhood Wheezing in Infants
The primary objective of this study is to assess the efficacy of motavizumab compared to placebo when administered monthly to preterm infants during their first RSV season for the reduction of the incidence of serious early…
- Trial name
- NCT00628303
- Testing
- Motavizumab
- Volunteers
- healthy volunteers welcome
- Sponsor
- MedImmune LLC
COVID-19
Collecting Respiratory Sound Samples From Corona Patients to Extend the Diagnostic Capability of VOQX Electronic Stethoscope to Diagnose COVID-19 Patients
Technological developments in the recent decades has enabled the integration of electronic and digital components in the stethoscope design, in an attempt to improve auditory performance and, moreover, to assist in improving…
- Trial name
- NCT04910191
- Testing
- Electronic stethoscope
- Where
- 3 sites in Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sanolla
Snoring
In Home Assessment of Three Anti-Snoring Devices, a Cross Over Study
Silent Night is a solution for primary snorers to guide them to the proper anti-snoring solution. It consists of a mobile application, which had an intake questionnaire, guides users to one of three anti-snoring solutions; a…
- Trial name
- NCT03333876
- Testing
- Nasal Dilator, Mandibular Advancement, Positional Therapy
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Philips Respironics
Sleep Apnea, Obstructive
Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person repeatedly stops breathing, or experiences shallow breathing for short periods of time during sleep.
- Trial name
- NCT00393913
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Snoring
Home-Use Impact and Effectiveness of Cloud 9
This is an interventional study in which patients with a history of habitual snoring will use the low-pressure CPAP device at home for about 4 weeks.
- Trial name
- Cloud9 (NCT02688335)
- Testing
- Cloud9
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Acute Bronchiolitis
FeNO and Cytokines in Respiratory Syncytial Virus (RSV) and Non RSV Bronchiolitis in Relation to Future Asthma
The purpose of this study is to determine Fractional exhaled Nitric-Oxide (FeNO)levels and blood cytokines during acute bronchiolitis, and to seek for correlation between these markers and future development of asthma.
- Trial name
- NCT02093715
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Bronchiolitis
A Study of Hypertonic Saline for Infants Hospitalized With Bronchiolitis
The purpose of this study is to determine if nebulized hypertonic saline (or extra salty water mist) helps infants less than 12 months old hospitalized with bronchiolitis (or bad chest colds) get better enough to be discharged…
- Trial name
- NCT01488448
- Testing
- 3% sodium chloride, 0.9% sodium chloride
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Asthma, Wheezing
Evaluation of Toxic Metals, Trace Elements and Total Antioxidant Activity in Children With Recurrent Wheezing
The purpose of this study is to evaluate hair trace elements and toxic metals and plasma total antioxidant activity in children with recurrent wheezing and to evaluate whether these toxic metals and trace elements have any impact…
- Trial name
- NCT00749528
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Sleep Deprivation
Chronic Sleep Restriction and Driving
Young subjects and patients with nocturnal respiratory disorders are frequently involved in sleep-related accidents. This study assess the impact of chronic sleep restriction (4 hr of sleep during 5 days) or total sleep…
- Trial name
- PRIVASOM (NCT00560456)
- Testing
- Chronic sleep restriction and driving simulator
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Snoring
OTC Mouthpiece for Snoring
Online patient registration to participate in clinical trial to test OTC mouthpiece that controls position of the tongue to reduce snoring.
- Trial name
- NCT03128307
- Testing
- Zyppah Anti-snoring Appliance
- Where
- United States
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Zyppah, Inc.
Lung Diseases
Data Collection Using Eko Devices in a Clinical Setting
The main objectives of the study are to: train and validate binary classifiers for wheeze, coarse crackle, fine crackle, rhonchus, stridor, rales, and cough, as well as determine correspondence between type/location of…
- Trial name
- NCT07270744
- Testing
- Eko digital stethoscopes
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eko Devices, Inc.
Lung Diseases
Data Collection For Adventitious Lung Sounds Algorithm Using Eko Digital Devices in a Clinical Setting
The purpose of this research is to collect patient lung sounds in order to develop an artificial machine learning algorithm that can potentially tell a doctor if a patient is at risk of certain lung conditions.
- Trial name
- NCT07360522
- Testing
- Eko digital stethoscopes
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Eko Devices, Inc.
Healthy
Vibration Response Imaging in Healthy Subjects
The primary purpose is to test intersubject variability and establish the qualitative features of normal VRI images and the range of normality of the VRI quantitative lung data values that may be used to differentiate normal from…
- Trial name
- NCT00495430
- Where
- Israel
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Deep Breeze
Snoring, Mouth Breathing
OA Therapy for Mouth-breathers Who Snore
Breathing is one of the body's vital functions that occur under normal conditions using the nose. When humans breathe primarily through the mouth instead of the nose, this is referred to as mouth breathing.
- Conditions
- Snoring, Mouth Breathing, Obstructive Sleep Apnea
- Trial name
- OATMB (NCT04876625)
- Testing
- myTAP oral appliance plus mouth shield, myTAP oral appliance alone for first 4 weeks
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Snoring
Nasal Appliance for the Treatment of Snoring in Adult Subjects - A Pilot Study
This is an open, pilot study for adults ( age range of 20-70 years old), who suffer from snoring without obstructive sleep apnea (OSA) and no need for CPAP treatment: with standard diagnosis of sleep study or with minor sleep…
- Trial name
- NCT02952118
- Testing
- Forrest Snoring device
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GE Sleeping