Clinical trials: Respiratory System
Healthy Participants
PF-07321332/Ritonavir and Ritonavir on Dabigatran Study in Healthy Participants
This is a drug-drug interaction study to assess the effects of PF-07321332/ritonavir and ritonavir on the Pharmacokinetic (PK) of dabigatran in healthy volunteers. PK will be evaluated for PF-07321332 and ritonavir.
- Trial name
- NCT05064800
- Testing
- Dabigatran, PF-07321332/ritonavir + Dabigatran, Ritonavir + Dabigatran
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
NSCLC Stage IV, Brain Metastases
Camrelizumab Combined With Local Treatment in NSCLC Patients With BM
To evaluate the efficacy and safety of Camrelizumab Combined with Chemotherapy and Local Treatment in non-small cell lung cancer with brain metastases.
- Conditions
- NSCLC Stage IV, Brain Metastases, Immunotherapy
- Trial name
- NCT04291092
- Testing
- Immunotherapy, WBRT, Chemotherapy
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Zhejiang Cancer Hospital
Lung Disease, Lung Disorder
Effects of Electronic Cigarettes on Lung Biology
E-cigarettes are an increasingly popular alternate nicotine delivery system, but nothing is known about the effects of electronic cigarettes on the lungs.
- Trial name
- NCT02188511
- Testing
- Group A, Group B, Group C
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Asthma, Asthma Patients
The Effect of Thyme Oil in Asthmatic Patients
This study is a pre-test post-test randomized controlled trial aimed at examining the effects of thyme oil inhalation on asthma control and respiratory parameters in patients with asthma.
- Trial name
- NCT06664671
- Testing
- Experimental, Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Inonu University
Breast Cancer, Colon Cancer
The Efficacy of Health Partnership Program for Cancer Patients
The Objectives of this study is 1. To evaluate the efficacy for exercise, diet, and posttraumatic growth as a result of participating in tailored program (Health Partnership Program) for 24 weeks 2.
- Conditions
- Breast Cancer, Colon Cancer, Gastric Cancer, Lung Cancer
- Trial name
- NCT01527409
- Testing
- Tailored health partnership program, Usual care and health education workshop
- Where
- 10 sites in South Korea
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Interstitial Lung Disease Due to Systemic Disease
Registry of Autoimmune Interstitial Lung Disease
Interstitial lung diseases (ILD) constitute a group of entities characterized by inflammation and/or fibrosis of the lung parenchyma.
- Trial name
- EPIMAR (NCT05365009)
- Testing
- Multidisciplinary aproach
- Where
- Argentina
- Volunteers
- 1,000 people
- Sponsor
- EPIMAR registry
Cystic Fibrosis, Bronchiectasis
Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients
This is a Phase 1, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability and pharmacokinetics of a single ascending doses (SAD) and multiple ascending doses (MAD) of Hypothiocyanite (OSCN-)…
- Trial name
- NCT02598999
- Testing
- ALX-009, OSCN-, bLF
- Where
- France
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Alaxia SAS
Neck Pain
Distance Learning and Neck Problems During Pandemic Period
For people who use computers a lot, Work-related musculoskeletal disorders of the neck are a common problem . It is generally agreed that the etiology of work-related neck disorders is multidimensional which is associated with…
- Trial name
- NCT04925999
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Misr University for Science and Technology
Seasonal Allergic Rhinitis
Study to Assess the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Cetirizine Alone on Symptoms in Patients With Allergic Rhinitis
The aim of this study is to assess the efficacy on nasal congestion and other allergic symptoms and the onset of action of an oral combination of cetirizine and pseudoephedrine in comparison to the single substances under…
- Trial name
- NCT00334698
- Testing
- Cetirizine, Pseudoephedrine, Cetirizine with Pseudoephedrine
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Post-COVID-19 Syndrome, Post-COVID Syndrome
Immunoadsorption Study Mainz in Adults With Post-COVID Syndrome
The aim of this study is to evaluate the efficiency and safety of immunoadsorption for the treatment of post-COVID syndrome (PCS).
- Conditions
- Post-COVID-19 Syndrome, Post-COVID Syndrome, Post COVID-19 Condition
- Trial name
- IAMPOCO (NCT05841498)
- Testing
- Immunoadsorption
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Medical Center Mainz
Acute Lung Injury
Transpulmonary Pressure Gradients in High Frequency Oscillation
Patients with severe lung conditions occasionally require support with a special ventilator (breathing machine) called the High Frequency Oscillator (HFO).
- Trial name
- TPG in HFO (NCT01321398)
- Testing
- Esophageal Pressure Monitoring
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University of British Columbia
Lung Cancer
Evidence-Based Nursing for Fatigue and Quality of Life in Lung Cancer Chemotherapy
This prospective randomized controlled trial investigated the effects of an evidence-based nursing intervention under a quantitative assessment strategy (EB-NQAS), utilizing the Edmonton Symptom Assessment Scale (ESAS), on…
- Trial name
- NCT07049237
- Testing
- Evidence-Based Nursing Under Quantitative Assessment Strategy (EB-NQAS), Routine Nursing Care
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The First Hospital of Hebei Medical University
Covid19, Endoplasmic Reticulum Stress
High GRP78 Levels in Covid-19 Infection: A Case-Control Study
Covid-19 infection was declared a global pandemic by WHO on March 11, 2020. GRP78 protein is known to be involved in the intrusion of numerous viruses.
- Trial name
- NCT04628637
- Testing
- Serum protein level analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Kafkas University
Lung Diseases, Age >18 Years-old
Optimization of Chest Tube Drainage Management
Early recovery after surgery was new developing science in recent years. However , there was few reports in thoracic surgery field .
- Conditions
- Lung Diseases, Age >18 Years-old, Patient Who Received Thoracoscope Surgery
- Trial name
- NCT03791437
- Testing
- Digital chest drainage system, Not use Digital chest drainage system
- Where
- Taiwan
- Volunteers
- 253 people
- Sponsor
- Chang Gung Memorial Hospital
Nasal Obstruction Septal Deviation Compensatory Inferior Turbinate Hypertrophy
Compensatory Inferior Turbinate Surgery in Septorhinoplasty
Nasal obstruction is a common complaint among patients undergoing septorhinoplasty. In addition to septal deviation, compensatory inferior turbinate hypertrophy may contribute to impaired nasal airflow.
- Trial name
- CIT (NCT07481045)
- Testing
- Septorhinoplasty, Inferior Turbinate Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Respiratory Syncytial Virus Infections
RV568 - Viral Challenge With RSV
RV568 is being developed for the treatment of diseases such as asthma, COPD and allergic rhinitis (e.g. hayfever). The main aim of this study is to investigate whether RV568 is effective in reducing the inflammation caused by…
- Trial name
- NCT01230645
- Testing
- RV568
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Respivert Ltd
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Lung Function and Respiratory Muscle Strength Following Training of the Inspiratory Muscles in Frail Older Adults (IMT-3)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on lung function and respiratory muscle strength in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07556445
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Thymoma, Stomach Neoplasms
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
Background: Malignant mesothelioma is a malignancy arising from the mesothelial cells of the pleura, peritoneum, pericardium, or tunica vaginalis. Mesothelioma accounts for 0.10% of deaths annually in the United States.
- Conditions
- Thymoma, Stomach Neoplasms, Pancreatic Neoplasms, Mesothelioma
- Trial name
- NCT01950572
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Cancer Institute (NCI)
In Escalation: All Patients With Solid Tumors and Lymphoma, In Expansion: Melanoma, Non-small Cell Lung Cancer
A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab
The purpose of this phase I/Ib study was to determine the safety profile of NIZ985 (new formulation), and if it could be safely combined with spartalizumab or tislelizumab and to determine the appropriate dose and schedule for…
- Trial name
- NCT04261439
- Testing
- NIZ985, Spartalizumab, Tislelizumab
- Where
- 9 sites in United States, Belgium and 5 more
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Aging, Menopause
Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.
- Conditions
- Aging, Menopause, Hypoxia, Vasodilation
- Trial name
- NCT06417177
- Testing
- Propranolol, Gemtesa
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
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