Clinical trials: Respiratory Tract Infection Viral
Influenza
Safety and Immunogenicity of a Commercially Available Influenza Vaccine (Formulation 2007/2008) When Administered to NON Elderly AND Elderly Subjects
To evaluate the antibody response to each influenza vaccine antigen when administering a single dose to subjects aged > 18 years
- Trial name
- NCT00518726
- Testing
- Surface Antigen, Inactivated, Adjuvanted, Influenza Vaccine, Formulation 2007-2008
- Where
- 3 sites in Italy
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Covid19
Intermediate-dose vs Standard Prophylactic Anticoagulation and Statin vs Placebo in ICU Patients With COVID-19
In a 2x2 factorial design randomized controlled trial, the investigators aim to elaborate the safety and efficacy of two pharmacological regimens on outcomes of critically-ill patients with COVID-19.
- Trial name
- INSPIRATION (NCT04486508)
- Testing
- intermediate dose Enoxaparin/ unfractionated heparin, standard prophylactic dose Enoxaparin/ unfractionated heparin, Atorvastatin 20mg
- Where
- Iran
- Volunteers
- 600 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
EGD, Covid19
Aerosol Particle From EGD in Patients With and Without Head Box in COVID-19 Era
According to preexisting data, it has revealed the fundamental role that aerosols play in the transmission of the COVID-19 virus.
- Conditions
- EGD, Covid19, Aerosol Disease, Head Box
- Trial name
- NCT04981535
- Testing
- Head box during upper gastrointestinal endoscopy
- Where
- Thailand
- Volunteers
- 190 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Covid-19, Respiratory Insufficiency
Convalescent Plasma in the Treatment of Covid-19
One hundred patients hospitalized and in need of oxygen treatment due to Covid-19 should be randomized and 50% treated with 200 ml convalescent plasma x 3 and 50% given ordinary treatment.
- Trial name
- COP20 (NCT04600440)
- Testing
- Convalescent plasma
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Skane University Hospital
COVID-19
Dornase Alpha for the Treatment of COVID-19
In this study, the effectiveness of the Dornase Alpha treatment, which is known to reduce the viscosity of respiratory secretions, will be investigated in new diagnosed and severe COVID-19 patients separately.
- Trial name
- NCT04432987
- Testing
- Pulmozyme
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Psoriasis, Covid19
PsoVac: Educational Needs re Vaccines for Biologic Patients With Psoriasis
To determine if there is a need for further education on vaccines with psoriasis patients who are on a biologic. In regards to the COVID-19, it is important that psoriasis patients - whether on a biologic or not - understand…
- Trial name
- NCT04513847
- Where
- Canada
- Volunteers
- 661 people
- Sponsor
- Dermatrials Research
Covid19
A Clinical Study to Evaluate MW33 Injection
This randomized, double-blind, placebo-controlled, single-dose escalation trial will be conducted to evaluate the safety, tolerability, immunogenicity, pharmacokinetic and pharmacodynamic characteristics of a single dose of MW33…
- Trial name
- NCT04533048
- Testing
- MW33 injection
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
Influenza
Evaluating the Safety and Immunogenicity of a Live Attenuated Virus Vaccine to Prevent Influenza H3N2v Disease
This study will evaluate the safety and immunogenicity of the H3N2v MN 2010/AA ca live attenuated influenza vaccine (H3N2v LAIV) in healthy children and adults, 6 to 26 years old.
- Trial name
- NCT02883426
- Testing
- H3N2v MN 2010/AA ca live attenuated influenza vaccine (LAIV), H3N2v inactivated subvirion influenza vaccine
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Non-allergic Rhinitis.
Kinetic Oscillation Stimulation (KOS) of Nasal Mucosa in Non-allergic Rhinitis: Investigation of Treatment Procedure
The purpose of the study is to evaluate how treatment with Kinetic Oscillation Stimulation (KOS) in the nasal cavity in patients with non-allergic rhinitis can be optimized to minimize any patient reported discomfort during…
- Trial name
- NCT02136043
- Testing
- PBASE system 1.1 (active treatment)
- Where
- Sweden
- Volunteers
- 29 people
- Sponsor
- Halmstad County Hospital
Postnatal Depression
Impact of Giving Birth During the Covid 19 Pandemia on Postnatal Women's Depression
Postnatal depression is an important problematic in French population with approximatively 10 -20% of women who suffer from postnatal depression. This pathology may have strong negative impact on both women and neonate's health.
- Trial name
- DEPRECOVID (NCT04368208)
- Testing
- Assessment of postnatal depression using the the Edinburgh questionnaire between 4 and 6 weeks after delivery
- Where
- France
- Volunteers
- 501 people
- Sponsor
- Poitiers University Hospital
Pneumonia, Pneumocystis Carinii, HIV Infections
An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved Therapies
To determine the safety and effectiveness of an investigational drug therapy (trimetrexate plus leucovorin calcium (TMTX / LCV)) in the treatment of Pneumocystis carinii pneumonia (PCP) in patients who have AIDS, are HIV…
- Trial name
- NCT00000714
- Testing
- Trimetrexate glucuronate, Leucovorin calcium
- Where
- 21 sites in United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19
Message Communicating Latest Data on COVID-19 Transmission in Patient's Area
This experiment is part of a megastudy with a total of ten experimental conditions and a holdout control condition to which patients will be randomly assigned.
- Trial name
- NCT05621226
- Testing
- COVID Booster text messages
- Where
- United States
- Volunteers
- 520,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
COVID-19, SARS-CoV-2
Professional's Health in Epidemiological Crisis Covid-19
Introduction: Coronavirus Disease 2019 (COVID-19) has caused a global pandemic. Epidemiological and clinical inter-individual differences, symptomatology, recovery and humoral response against Severe Acute Respiratory Syndrome…
- Trial name
- ProHEpiC-19 (NCT04885478)
- Testing
- Immune response monitoring , blood samples
- Where
- Spain
- Volunteers
- 1,350 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Malnutrition, Cancer
Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients
This study aims to compare nutritional outcomes in terms of percentage of weight gain between a new planted-based high-energy ONS and a standard high-energy ONS with animal protein (cow's mil protein) in patients at malnutrition…
- Conditions
- Malnutrition, Cancer, Inflammatory Bowel Diseases, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06055543
- Testing
- Fortimel
- Where
- 6 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Danone Specialized Nutrition
Pancreatic Cancer
Immunotherapy Combined With Radiation and Influenza Vaccine for Pancreatic Cancer.
Pancreatic cancer (PC) remains a dreadful disease due to its often advanced stage at diagnosis and poor sensitivity to chemotherapy. Progression after 1.
- Trial name
- INFLUENCE (NCT05116917)
- Testing
- Nivolumab, Ipilimumab, Influenza vaccine
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- Herlev Hospital
COVID-19, Complication of Anesthesia
Association Between Post-covid Infection Status and Perioperative Morbidity: A Ambispective Cohort Study
With the knowledge of currently transmitted omicron variant being less virulent, over 90 percent of the Chinese population is fully vaccinated, and the Chinese health workers have sufficient experience treating the illness.
- Conditions
- COVID-19, Complication of Anesthesia, Complication of Surgical Procedure, Complication,Postoperative
- Trial name
- NCT05689840
- Testing
- Receiving inpatient surgical intervention
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Peking Union Medical College Hospital
COVID - 19
Vitamin E Supplementation As Adjunctive Therapy To Lower Inflammation In COVID-19 Patients
Since the first reported case of the novel coronavirus (SARS-CoV-2) in humans at the end of 2019 in Wuhan, the virus had infected approximately 100 million individuals.
- Trial name
- VITEC (NCT07412574)
- Testing
- Patients were randomly assigned, under a double-blind design, α-Tocopherol group (n = 22)
- Where
- Mexico
- Volunteers
- 56 people
- Sponsor
- Universidad Veracruzana
COVID-19, Pulmonary Fibrosis
Comparison of Pulmonary Telerehabilitation and Physical Activity Recommendations in Patients With Post Covid Fibrosis
Rehabilitation plays a very important role in the management of patients with COVID-19, focusing on respiratory and motor functions, and therefore the importance of establishing treatment strategies to ensure optimal recovery of…
- Trial name
- NCT05299333
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
COVID-19, Neonatal Disease
Characteristics of Neonatal Covid-19 in Turkey
The investigators aimed to investigate the clinical and epidemiological characteristics of neonates who will be born to Covid-19 positive mothers in Turkey.
- Conditions
- COVID-19, Neonatal Disease, Healthy
- Trial name
- NCT04401540
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Type 2 Diabetes Mellitus, COVID-19
Role of Tele-physical Therapy in Patients With Type 2 Diabetes Mellitus Following COVID-19 Infection.
Diabetes mellitus (DM) is a chronic metabolic disease where the body is unable to metabolize carbohydrates properly either due to a lack of insulin production or abnormal insulin function.
- Trial name
- NCT05599893
- Testing
- Tele physical therapy, Patient educationa and Conventional exercises
- Where
- Saudi Arabia
- Volunteers
- 136 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
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