Clinical trials: Respiratory Tract Infections (RTI)
Influenza, Virus Diseases
Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults
Avian influenza (AI), or bird flu, has recently become a major health concern in Asia and other parts of the world. The need for a vaccine to prevent the spread of AI among livestock and to humans is sorely needed.
- Trial name
- NCT00347672
- Testing
- H5N1 (6-2) AA ca Recombinant (A/VietNam/1203/2004 x A/AnnArbor/6/60/ca)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19, Pulmonary Fibrosis
COVID-19 Pathophysiology of Long Term Implications
Coronavirus disease 2019 (COVID 19) is primarily a respiratory viral infection. At the time of writing this protocol, more than 25 million people have been affected globally.
- Conditions
- Covid19, Pulmonary Fibrosis, Organising Pneumonia, Thromboembolism
- Trial name
- NCT04813575
- Testing
- Cryo lung biopsies
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
COVID-19, SARS-CoV-2 Infection
A Study to Evaluate the Immunogenicity and Safety of A Recombinant Protein COVID-19 Vaccine as Booster Vaccines
This study is a phase Ⅱ clinical trial to evaluate the safety and immunogenicity of SCTV01E-2 in people of different ages who had been vaccinated with COVID-19 vaccines.
- Trial name
- NCT05933512
- Testing
- SCTV01E-2, SCTV01E
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
COVID-19
The Effects of Long-Term Mask Use in the Pandemic Period
Various restrictions have been made all over the world due to coronavirus pandemics. In addition to situations such as social isolation and hygiene, the use of masks is among these rules.
- Trial name
- NCT05358665
- Testing
- mask use
- Where
- Turkey (Türkiye)
- Volunteers
- 909 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
COVID 19
Assesment of the Metabolomic Signature in COVID-19 Patients
Metabolomics is the analysis of small molecules in a biological sample (cells, tissues or biological fluids). It can potentially detect very sensitively any change related to a pathology or exposure to a toxic agent.
- Trial name
- SignCov (NCT04497272)
- Testing
- COVID-19 patients
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
COVID-19
Study to Evaluate a Single Dose of LTX-109 in Subjects With COVID-19 (Coronavirus Disease 2019) Infection.
A Phase IIa, double-blind, placebo-controlled, randomised study designed to evaluate the effect, safety and tolerability of LTX-109 administered topically to the anterior nares in subjects with COVID-19 infection.
- Trial name
- NCT04854928
- Testing
- LTX-109 gel, 3%
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Pharma Holdings AS
Covid19
The Application of a Mask in Patients With Severe Covid-19 Already Treated With High-flow Nasal Cannula.
Patients with severe hypoxemic respiratory failure due to Covid-19 are often treated with oxygen delivered through a high-flow nasal cannula (HFNC). This is according to guidelines.
- Trial name
- NCT04794400
- Testing
- oxygen mask
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Region Skane
COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction
COVID-19 Vaccination Detoxification in LDL-C
The study hypothesizes that SARS-CoV-2 vaccination poisoning hibernates in human host in Low Density Lipoprotein Cholesterol (LDL-C). The clinical trial is a follow-up from the intervention trial with NCT number NCT05711810.
- Conditions
- COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction, COVID-19-Associated Thromboembolism, COVID-19 Post-Intensive Care Syndrome
- Trial name
- NCT05839236
- Testing
- Atorvastatin Calcium Tablets
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis
BRONCHIOLITIS
Comparison of 3% Hypertonic Saline and Salbutamol in Children With Bronchiolitis
Bronchiolitis is a common lower respiratory tract infection that often leads to hospitalization in infants. The use of nebulized 3% hypertonic saline for treating bronchiolitis is being explored as an alternative to Salbutamol.
- Trial name
- NCT06665711
- Testing
- 3% Hypertonic Saline, Intervention: Salbutamol (Ventolin)
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Frail Elderly Syndrome, Elderly Infection
Effect of Alfacalcidol to Respiratory Infection and Immune Response of Indonesian Elderly
Vitamin D has been known to influence immune response through Vitamin D Receptor in Immune Cells, but only few has been known about the effect alfacalcidol, a vitamin D analog to immune system.
- Trial name
- NCT03292744
- Testing
- Alfacalcidol
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
COVID-19, Telerehabilitation
Teletechnology-assisted Home-based Exercise Program for Severe COVID-19
The aim of this study was to investigate the efficacy of a home-based pulmonary rehabilitation program with the support of teletechnology in COVID-19 survivors.
- Trial name
- NCT05778344
- Testing
- Teletechnology-assisted home-based pulmonary rehabilitation
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Long COVID Syndrome
Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?
Millions have developed Long COVID (LC), and recent findings show an association between taurine deficiency (an amino acid) and symptoms in LC.
- Trial name
- NCT07312409
- Testing
- Taurine supplementation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- York University
Face Mask Squeeze, COVID-19
Face Mask Habits and COVID-19 Among University Students in Cairo
The World Health Organization officially declared the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a public health emergency.
- Conditions
- Face Mask Squeeze, COVID-19, Pandemic, COVID-19
- Trial name
- NCT05517629
- Testing
- It is an observational cross-sectional study
- Where
- Egypt
- Volunteers
- 1,455 people
- Sponsor
- Benha University
Influenza
To Identify the Immunogenicity and Safety of QIV in Children Aged 3-8 Years
To explore the immunogenicity and safety of quadrivalent split influenza virus vaccine in children aged 3-8 years with two doses and one dose.
- Trial name
- QIV (NCT05389137)
- Testing
- Inavtivated Quadrivalent Influenza Virus Split Vaccine
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Wuhan Institute of Biological Products Co., Ltd
COVID-19
COVID-19 Endoscopy Survey
A questionnaire containing some critical questions about practice inside GI endoscopy units in different countries will be distributed via emails.
- Trial name
- COVID-19 Endo (NCT04342637)
- Testing
- Practice details
- Where
- 4 sites in United States, Egypt and 1 more
- Volunteers
- 163 people
- Sponsor
- Al-Azhar University
Recurrent Tonsillitis, Peritonsillar Abscess
Auricular Acupuncture for The Treatment of Post-Tonsillectomy Pain
The goal of this study is to assess the role of battlefield acupuncture in the reduction of pain scores status post adult tonsillectomy.
- Conditions
- Recurrent Tonsillitis, Peritonsillar Abscess, Obstructive Sleep Apnea
- Trial name
- NCT01790477
- Testing
- Auricular Acupuncture
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Sore Throat, Pharyngitis
APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat
The primary objective of this study is to evaluate the efficacy of APC 111 MP Tablet, 775 mg tablet, given orally (PO)once daily (QD) for 10 days compared to that of Penicillin VK, 250 mg PO four times daily (QID) for 10 days in…
- Conditions
- Sore Throat, Pharyngitis, Tonsillitis
- Trial name
- NCT00242281
- Testing
- APC-111 MP Tablet, 775 mg
- Where
- 41 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Advancis Pharmaceutical Corporation
Shortness of Breath, Acute Respiratory Failure
Enhanced FoCUS in Patients With Shortness of Breath
Retrospective observational study performed in a internal medicine ward of a French university hospital. Included patients were hospitalized for acute shortness of breath who have benefited from a eFOCUS which was defined as a…
- Trial name
- eFOCUS (NCT05403619)
- Testing
- Diagnostic test
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Nantes University Hospital
Influenza Infection
Effect of the Interferon Alpha Citizen by Sub-Lingual Way on the Humoral Immunizing Answer
Influenza vaccination reduces the morbidity and mortality associated with influenza infection in at risk groups including the elderly and individuals with an impaired immune response, but is not totally protective in all…
- Trial name
- GP-INFA (NCT00647465)
- Testing
- vaccine
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
SARS-CoV Infection
Tele-health Enabled Clinical Trial for COVID-19
To determine the efficacy of high dose Vitamin D (an over-the-counter nutritional supplement) in preventing immune-related complications in outpatients with confirmed SARS-CoV-2 infection.
- Trial name
- NCT04489628
- Testing
- Doctella telehealth monitoring
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.