Clinical trials: Respiratory Viruses
Sore-throat, Common Cold
A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Throat Spray on the Incidence and Duration of Sickness
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of Beekeeper's Naturals Propolis Immune Support Throat Spray on the incidence and duration of sickness over a 16-week period.
- Trial name
- NCT07246850
- Testing
- Beekeeper's Propolis Throat Spray
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beekeeper's Naturals Inc
Influenza
Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in Adults
A Phase 2b Study to Determine the Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in Adults aged 18 years and over. To assess the effect of MVA-NP+M1 on the reduction of laboratory confirmed influenza when given as an adjunct…
- Trial name
- NCT03880474
- Testing
- MVA-NP+M1, Saline
- Where
- 9 sites in Australia
- Volunteers
- 2,364 people, healthy volunteers welcome
- Sponsor
- Barinthus Biotherapeutics
Olfactory Dysfunction, Covid19
Acupuncture for Olfactory Dysfunction in Infected COVID-19 Patients
In this a 12-week, single blinded, randomized sham controlled, and cross-over clinical trial. It will be conducted to explore the safety and efficacy of acupuncture for olfactory dysfunction in infected COVID-19 patients in Hong…
- Trial name
- NCT04959747
- Testing
- acupuncture
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Hong Kong Baptist University
Covid19
Geriatric Care for Older People Hospitalised for COVID-19
Current COVID-19 pandemic implies regular treatment adaptation by physician, according to scientific publication evolution. Older adults are particularly affected by COVID-19, with the higher severe form prevalence and the higher…
- Trial name
- COVAGERT (NCT04947943)
- Where
- France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Montpellier
COVID-19
Reducing COVID-19 Related Hospital Admission in Elderly by BCG Vaccination
Bacillus Calmette-Guérin (BCG) vaccine not only protects against tuberculosis, but has also been shown to induce protection against various infections with a viral aetiology, leading to significant reductions in morbidity and…
- Trial name
- NCT04417335
- Testing
- BCG vaccine
- Where
- 2 sites in Netherlands
- Volunteers
- 2,014 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
COVID-19
Methodist Health System COVID-19 Patient Registry
This is a prospective cohort observational registry study that will include data on all patients who are treated at MHS facilities for COVID-19.
- Trial name
- NCT04477889
- Testing
- Treatment for COVID-19
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Methodist Health System
Covid19
Characterisation of the Immune Response to SARS-CoV-2 / COVID-19
Emerging clinical details of the current SARS-CoV-2 pandemic have illustrated that there are multiple clinical presentations and outcomes of this viral infection.
- Trial name
- NCT04729452
- Testing
- blood test
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cwm Taf University Health Board (NHS)
COVID-19
A Study of Efficacy and Safety of Azvudine vs. Nirmatrelvir-Ritonavir in the Treatment of COVID-19 Infection
The COVID-19 pandemic has become a major public health challenge, and the treatment options for the disease are currently limited.
- Trial name
- NCT05697055
- Testing
- Azvudine, Nirmatrelvir-Ritonavir
- Where
- China
- Volunteers
- 410 people
- Sponsor
- Shandong Provincial Hospital
SARS-CoV-2 Acute Respiratory Disease, SARS-CoV-2 Sepsis
The Corona Study of Middle Norway
CUT COVID is a cohort study establised to collect information on patients hospitalized because or with infection by SARS-CoV-2. The cohort data includes clinical data and biological samples from multiple timepoints during…
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, SARS-CoV-2 Sepsis, SARS CoV 2 Infection
- Trial name
- CUT COVID-19 (NCT05638178)
- Testing
- No intervention
- Where
- 5 sites in Norway
- Volunteers
- 223 people
- Sponsor
- St. Olavs Hospital
Coronavirus Infection
Change in the Ratio of Mean Platelet Volume (MPV) to Platellet(PLT) in Covid-19 Pneumonia Patients
Morbidity, mortality and progress depends on systemic inflammation especially in ARDS patients. Previous studies claims that the proportion of mean platellet volume to platellet which can simply be determined with simple blood…
- Trial name
- NCT04408378
- Testing
- observation of covid 19 pneumonia
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
COVID-19
Safety and Immunogenicity Study of Inactivated Vaccine for Prophylaxis of SARS CoV-2 Infection (COVID-19)
This study is a randomized, double-blinded, and placebo controlled phase Ⅰ/Ⅱ clinical trial of the SARS-CoV-2 inactivated vaccine manufactured by Sinovac Research \& Development Co., Ltd.
- Trial name
- NCT04352608
- Testing
- Two doses of medium dosage inactivated SARS-CoV-2 vaccine at the emergency vaccination schedule, Two doses of high dosage inactivated SARS-CoV-2 vaccine at the emergency vaccination schedule, Two doses of medium dosage inactivated SARS-CoV-2 vaccine at the routine vaccination schedule
- Where
- China
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
COVID-19
Study to Evaluate the Safety and Efficacy of Liquid Alpha1-Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19)
The purpose of the study is to determine if Liquid Alpha1-Proteinase Inhibitor (Human) (Liquid Alpha1-PI) plus SMT can reduce the proportion of participants dying or requiring intensive care unit (ICU) admission on or before Day…
- Trial name
- NCT04547140
- Testing
- Liquid Alpha1-Proteinase Inhibitor (Human), Standard Medical Treatment
- Where
- 20 sites in United States, Brazil and 3 more
- Volunteers
- 57 people
- Sponsor
- Grifols Therapeutics LLC
COVID-19 Pneumonia
Evaluate the Efficacy and Safety of TF0023 in Treatments for COVID-19 in Hospitalized Adults
Techfields Inc. is developing a new investigational prodrug as a topical spray, indicated for relief of the signs and symptoms of ARDS and pneumonia caused by COVID-19.
- Trial name
- NCT05212818
- Testing
- TF0023
- Where
- 5 sites in United States, South Africa
- Volunteers
- 19 people
- Sponsor
- Techfields Inc
Covid19
Evolution of COVID-19 in Anticoagulated or Antiaggregated Patients (CORONA Study)
CORONA is a retrospective, observational, one center study to investigate the clinical evolution (in terms of survival and thromboembolic complications) of patients on chronic treatment with anticoagulants or antiplatelet agents…
- Trial name
- CORONA (NCT04518735)
- Testing
- Antithrombotic Therapy (anticoagulant and/or antiplatelet) before admission for Covid19
- Where
- Spain
- Volunteers
- 1,707 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
RSV Infection
Impact of the Covid-19 on Respiratory Syncytial Virus (RSV) Epidemic
The magnitude of seasonal Respiratory Syncytial Virus (RSV) epidemics brings each year new logistical challenges for the hospitalization of young infants with bronchiolitis that overwhelm hospital capacities and lead to specific…
- Trial name
- IPCoVRS (NCT04944160)
- Testing
- Medical records analysis, Comparison of cohorts
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
COVID-19 Acute Respiratory Distress Syndrome
Rehabilitation of Critically Ill Patients With SARS-CoV-2 Variants in ICU With Limited Resources
Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. Scientific evidence has considered neuromuscular electrical stimulation (NMES) as a promising approach for the…
- Trial name
- NCT05450120
- Testing
- Functional Rehabilitation, Neuromuscular Electrical Stimulation
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Federal de Sao Carlos
COVID-19
Study of Niclosamide in Moderate and Severe Hospitalized Coronavirus-19 (COVID-19) Patients
Study of ANA001 in Moderate and Severe COVID-19 Patients
- Trial name
- NCT04603924
- Testing
- Niclosamide
- Where
- 8 sites in United States
- Volunteers
- 49 people
- Sponsor
- NeuroBo Pharmaceuticals Inc.
Covid19, Hypoxemia
Evaluation of a Low-cost CPAP Device on Hospitalized COVID-19 Patients
The aim of this study is to evaluate the preliminary safety and performance of a low-cost locally-made Venturi-based Non-invasive Positive Pressure Ventilator (NIPPV) device for hypoxemic COVID-19 patients.
- Trial name
- OxyJet-CPAP (NCT04681859)
- Testing
- High Flow Nasal Oxygen (HFNO) treatment, Continuous Positive Airway Pressure (CPAP) therapy using OxyJet
- Where
- Bangladesh
- Volunteers
- 45 people
- Sponsor
- Bangladesh University of Engineering and Technology
Coronavirus Infection, SARS (Severe Acute Respiratory Syndrome)
Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19
The overall objective of the study is to determine the therapeutic effect and tolerance of Tocilizumab combined with Dexamethasone in patients with moderate, severe pneumonia or critical pneumonia associated with Coronavirus…
- Conditions
- Coronavirus Infection, SARS (Severe Acute Respiratory Syndrome), Virus Diseases, Coronaviridae Infections
- Trial name
- TOCIDEX (NCT04476979)
- Testing
- Tocilizumab, Dexamethasone
- Where
- French Guiana
- Volunteers
- 453 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mental Health, Quality of Life
Impact of COVID-19 on Mental Health of Health Care Workers
The impact of the current Covid-19 pandemic on healthcare workers is enormous. This longitudinal study investigates the prevalence of mental health problems and the quality of life of healthcare workers during and after the…
- Trial name
- COVID-Impact (NCT04382196)
- Testing
- Online survey
- Where
- Belgium
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent