Clinical trials: Rest
Spinal Cord Injuries, Dietary Habits
Assessing Dietary Requirements in Relation to Resting Metabolic Rate in Spinal Cord Injury
Assess the relationship between body composition, metabolism, and dietary needs in people with spinal cord injury compared to their healthy controls that are age and sex matched.
- Trial name
- NCT03518892
- Testing
- Resting Metabolic Rate, Body Composition, Dietary Assessment
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Simulation of Weightlessness by Anti-Orthostatic Long Term Bed Rest
Toulouse Male Long Term Bed Rest 2001-2002
Microgravity during space flight induces physiological changes that affect astronauts' health and performance. Space flight simulations such as prolonged bed rest can mimic some of these changes and provide study conditions that…
- Trial name
- NCT00311571
- Testing
- Ethidronate, Physical training
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre National d'Etudes Spatiales
Therapeutic Mechanism of Antidepressants for Refractory FD
MRI Study of Antidepressants in the Treatment of Refractory Functional Dyspepsia
In this study, diffusion tensor imaging（DTI）technique was used to evaluate the brain microstructures and connective white matter microstructures in patients with refractory FD, resting fMRI was used to evaluate the functional…
- Trial name
- NCT03973567
- Testing
- selective serotonin reuptake inhibitor (SSRI) or serotonin noradrenaline reuptake inhibitor (SNRI) antidepressants, conventional therapy
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cystic Fibrosis
Cystic Fibrosis and Endothelial Function: At Rest and During Exercise
Perhaps one of the most disturbing aspects of Cystic Fibrosis (CF) is the associated premature death. Oxidative stress has been observed in patients with CF and exercise intolerance has been shown to predict mortality in patients…
- Trial name
- NCT01772758
- Testing
- BH4 5mg, BH4 20mg, Antioxidant Cocktail
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Augusta University
Physical Activities
Changes in Energy Expenditure in Response to Physical Activity in Healthy Adults
This study investigates how short, high-intensity body-weight exercises affect energy use in healthy young adults. The focus is on resting metabolic rate (RMR), total energy expenditure (TEE) and excess post-exercise oxygen…
- Trial name
- VITAL (NCT07529132)
- Testing
- physical activity
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Medical University of Bialystok
Chronic Pain
The Use of Resting State, fMRI and DTI in the Identification of Chronic Pain Conditions
Resting state fMRI scans of chronic pain sufferers will be compared to those of healthy normals and may be sufficiently different to allow a high level of classification accuracy of whether subjects have chronic pain.
- Trial name
- NCT02987933
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brain Scan Inc.
Insomnia
WELT-REST: WELT Randomized Evaluation of Sleep Therapy
The goal of this clinical trial is to learn whether the SleepQ mobile app can help reduce insomnia symptoms in adults diagnosed with insomnia.
- Trial name
- WELT-REST (NCT07289217)
- Testing
- SleepQ Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- WELT corp
Insulin Resistance
Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism
Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels.
- Trial name
- NCT06722391
- Testing
- Neuromuscular Electrical Stimulation (Sensory), Neuromuscular Electrical Stimulation, Resistance Training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Peripheral Arterial Disease
Functional MRI of the Lower Extremities
In this project, the investigators propose to use high-resolution magnetic resonance imaging (MRI) to measure blood perfusion in different groups of calf muscle.
- Trial name
- NCT03423316
- Testing
- Supervised exercise therapy
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial
Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest
This study is meant to compare the amount of oxygen required for hypoxemia relief between current standard of care (oxygen only) and oxygen with the addition of high flow air for Chronic Obstructive Pulmonary Disease (COPD)…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial, Pulmonary Fibrosis, Hypoxemia
- Trial name
- NCT04170062
- Testing
- Nasal Delivery of High-Flow Air and Oxygen Therapy, Nasal Delivery of Oxygen Therapy
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Johns Hopkins University
Heart Failure
Myocardial Performance at Rest and During Exercise in Heart Failure With Preserved Ejection Fraction
This study is being done to study how well the heart contracts and relaxes during exercise. In addition to traditional measures of heart function, we will use a new computer program that may improve understanding of why people…
- Trial name
- X-HF-SPECKLE (NCT01747785)
- Testing
- Cardiac rehabilitation, Myocardial deformation imaging, Cardiopulmonary exercise test
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Rest Cramps
Exploring the Role of Magnesium in Rest Cramps
This study sets out to show whether infusions of magnesium can lessen the frequency of rest cramps and to determine whether rest cramp sufferers have a deficiency in magnesium.
- Trial name
- NCT00423540
- Testing
- Intravenous Infusion of Magnesium Sulfate
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Insomnia
Impact of Insomnia Treatment on Brain Responses During Resting-state and Cognitive Tasks
Individuals with chronic insomnia have persistent difficulty falling and staying asleep, as well as complaints of altered daytime functioning that may be associated with cognitive impairments.
- Trial name
- NCT04024787
- Testing
- Cognitive-Behavioural therapy for insomnia (CBT-I)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Exercise Behavior, Multiple Myeloma
Exercise Phenotyping Prior to Chemotherapy in Newly Diagnosed Multiple Myeloma (MM-Exercise)
MM-Exercise is a prospective, single-centre, observational pilot study of patients with newly diagnosed multiple myeloma who have not yet started chemotherapy and whose resting echocardiogram is unremarkable or only mildly…
- Trial name
- MM-Exercise (NCT07851493)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Technical University of Munich
Lung Inflammation, Experimental Lung Inflammation
Pulmonary and Inflammatory Responses Following Exposure to a Low Concentration of Ozone or Clean Air at Rest
The primary purpose of this study is to measure pulmonary function, symptoms, and pulmonary inflammatory responses in healthy young adults during and immediately after exposure to a low concentration of ozone (0.070 ppm) or clean…
- Trial name
- LOCONOZ3 (NCT06943989)
- Testing
- Ozone Exposure, Clean air (0.0 ppm ozone)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Healthy Volunteers
Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
Background: Changes in how a person's body burns energy or calories can affect their weight over time. The lowest level of energy the body needs to function is called basal metabolic rate.
- Trial name
- NCT01950520
- Testing
- Propranolol, Pindolol, Dantrolene
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Sickle Cell Disease
Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET
There is limited information on what causes injury to the heart in individuals with Sickle Cell Disease (SCD). Researchers in this study want to see if decreased blood flow to the heart during stress could be causing the heart…
- Trial name
- NCT05583721
- Testing
- [13N]NH3, Lexiscan, Positron emission tomography
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Fasting, Intermittent Fasting
Time Restricted Feeding in Male Runners
This is a cross-over intervention study designed to evaluate how four weeks of time restricted feeding (16 hours fasting and 8 hours feeding), compared to four weeks of a more traditional eating pattern (12 hours fasting and 12…
- Conditions
- Fasting, Intermittent Fasting, Athletic Performance, Cardiovascular Risk Factor
- Trial name
- NCT03569852
- Testing
- Time Restrictive Feeding, Traditional Eating Pattern
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Contrast-Associated Acute Kidney Injury
Contrast-Associated Nephropathy Risk Evaluation in Acute Ischemic Stroke After Endovascular Thrombectomy
The CAN-REST study is a multicenter, observational, and retrospective study aimed at evaluating the incidence and risk factors of contrast-associated acute kidney injury (CA-AKI) in patients with acute ischemic stroke (AIS) who…
- Trial name
- CAN-REST (NCT06596603)
- Where
- Italy
- Volunteers
- 8,000 people
- Sponsor
- Niguarda Hospital
CEC Syndrome
Non-invasive Measurement of Compartment Pressure: Reliability
The investigators want to investigate the reliability (variability) of a new device, that should be able to measure lower leg compartment pressure non-invasively. Therefore the tool is used under different circumstances.
- Trial name
- NCT05720182
- Testing
- Compremium Compressibility Measurement, Treadmill Running, Questionnaire
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kay van Heeswijk