Clinical trials: Resting State Networks
Acute Depression, Major Depressive Episode
Study of Functional Networks in Resting fMRI
The primary purpose is to compare with resting fMRI the functional networks of rest (RTS) in unipolar depression and in bipolar depression.
- Trial name
- DEPIMAGE (NCT03323073)
- Testing
- Resting state fMRI
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Central Nervous System
Touch and Attention MRI Study
This study will measure resting state network central nervous system activity by functional magnetic resonance imaging (fMRI) during 4 separate interactions with a clinician. 1. Hypothesis 1.
- Trial name
- NCT01432288
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Cluster Headache, Headache Disorders
Resting State Functional Connectivity in Cluster Headache
Cluster headache is a highly disabling primary headache disorder, characterized by severe, excruciating, recurrent unilateral headache attacks.
- Trial name
- NCT06206772
- Testing
- Resting state HD-EEG recording
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Healthy
Transcranial Focused Ultrasound (tFUS) Modulation of Reward Network
Aim: Evaluate whether sonicating the Nucleus Accumbens (NAc) with transcranial focused ultrasound modifies functional connectivity between the NAc and the prefrontal cortex (PFC).
- Trial name
- NCT05986019
- Testing
- transcranial focused ultrasound (tFUS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Migraine Disorders, Chronic Migraine
HD-EEG Connectivity Changes in Migraine Patients Undergoing Treatment With Anti-CGRP mAbs
Migraine is a leading cause of disability with an estimated prevalence of 12% in Europe. The headache field witnessed a breakthrough since the introduction of specific preventive therapies which proved effective and well…
- Conditions
- Migraine Disorders, Chronic Migraine, Episodic Migraine
- Trial name
- NCT06155123
- Testing
- Monoclonal antibody targeting the CGRP pathway (ligand or receptor) (mAbs)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Parkinsons Disease (PD)
Neuroimaging of Parkinson's
Parkinson's Disease (PD) is a neurodegenerative disorder caused by dysfunction in both subcortical structures and the cortex. The investigators recently discovered a new brain system called the Somato-Cognitive Action Network…
- Trial name
- NCT07024875
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Amnesia
Transient Global Amnesia (TGA). Exploratory Study of the Default Mode Network During the Acute Phase
The transient global amnesia, in which the memory disorder is massive, transient and pure, offers a unique model for exploring episodic memory.
- Trial name
- ICTUS (NCT02010853)
- Testing
- IRMf
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Subthreshold Depression, Young People
TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.
The purpose of this study is to assess the mechanisms of the effect of transcranial direct current stimulation (tDCS) in alleviating subthreshold depressive symptoms in young individuals, and individualized outcome prediction is…
- Conditions
- Subthreshold Depression, Young People, Transcranial Direct Current Stimulation
- Trial name
- NCT06294184
- Testing
- tdcs lDLPFC, tdcs rVLPFC
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Fluid Inteligence, Modafinil
Pharmacological Cognitive Enhancement
There is growing debate on the use of drugs that can promote cognitive enhancement. Amphetamine-like drugs have been employed as cognitive enhancers, but all of them have important side effects and may induce addiction.
- Conditions
- Fluid Inteligence, Modafinil, Healthy Young Subjects, Resting State Networks
- Trial name
- MODREST (NCT01684306)
- Testing
- Modafinil
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Obesity
Effects of the GLP-1 Exenatide on Satiety in Lean and Obese Women
Obesity is a major health problem in the US and many Western countries, with more than half of the population being overweight or obese.
- Trial name
- NCT01501084
- Testing
- Exenatide, Normal saline .2cc subcutaneous injection
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Attention Deficit Hyperactivity Disorder
Disturbed Structural Connectivity of Frontostriatal and Frontoparietal Networks in Adults With ADHD
Attention deficit/hyperactivity disorder (ADHD) is a common, impairing, childhood onset neuropsychiatric disorder with executive dysfunctions. The ADHD symptoms and executive deficits may last to adulthood.
- Trial name
- NCT02232464
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Disorders of Consciousness
Resting State fMRI in Disorders of Consciousness
Disorders of consciousness (DoC) remain a major clinical challenge in which high rates of misdiagnosis and difficult prognostication stem from limitations in the ability to access the disordered physiological processes mechanisms…
- Trial name
- NCT05463029
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke, Motor Disorder
Effects of Brain Network by Simultaneous Dual-mode Stimulation in Subacute Stroke Patients
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03279640
- Testing
- rTMS on ipsilesional M1, tDCS on contralesional M1
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Acupuncture
Effectiveness of YNSA Acupuncture on Brain Networks
This study investigates the effects of a new form of acupuncture (Yamamoto's New Skull Acupuncture [YNSA]) on resting-state brain networks.
- Trial name
- NCT04795024
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Premature Ejaculation, Sexual Dysfunction
Brain Networks Implicated in Lifelong Premature Ejaculation Patients
Using Brain Mapping and Cognitive ERPs, the investigatos have searched for a Brain Networks involved during Inhibitory Control in Lifelong Premature Ejaculation (LPE) participants.
- Trial name
- LPE (NCT04850703)
- Testing
- Transcranial Radom Noise Stimulation, Take Dapoxetine, Compare LPE EEG endophenotype between participants and healthy controls
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Moises Domingo
Languages
Establishing the Language Network With Independent Component Analysis of Resting State MRI
Proceed to an analysis of sensitivity and specificity results of the fMRI language network obtained in two ways: by providing a conventional language test and independent component analysis.
- Trial name
- ICA Langage (NCT02577757)
- Testing
- MRI
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Autonomous Sensory Meridian Response, Audiobook
Effects of ASMR on the Default Mode Network
This study investigates the effects of Autonomous Sensory Meridian Response (ASMR) stimulation on resting-state brain networks. Therefore, two resting-state fMRI scans are measured in healthy adults.
- Trial name
- NCT05266508
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Brachial Plexus Neuropathies, Traumatic Brachial Plexus Lesion
Central Programming in Patients With a Bionic Hand After Traumatic Brachial Plexus Injury
Traumatic brachial plexus lesions may lead to permanent impairment of hand function despite brachial plexus surgery. In selected cases the affected forearm can be amputated and replaced by a bionic hand.
- Conditions
- Brachial Plexus Neuropathies, Traumatic Brachial Plexus Lesion, Bionic Hand Reconstruction
- Trial name
- NCT04649749
- Testing
- MRI
- Where
- Austria
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy
Trait Anxiety and Defensive Networks
to examine the association between trait and defensive network connectivity and the modulatory effect of oxytocin on it
- Trial name
- NCT02682888
- Testing
- trait anxiety scale, Oxytocin
- Where
- China
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China