Clinical trials: Restoration, active
Carious Lesion, Ready-made Crowns
The Relation Between Oral Hygiene and Microbial Load in the Oral Cavity After Restoring Primary Molars With Two Types of Ready-made Crowns
Following the restoration of primary molars with stainless steel and bioflex crowns, an evaluation of the current state of oral hygiene in relation to the amount of microorganisms and gingival health in the oral cavity will be…
- Trial name
- bioflex crown (NCT06767670)
- Testing
- stainless steel crown, bioflex crown
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Knee, ACL
Restoration of Knee Extension After ACL Reconstruction
The purpose of this study is to determine whether the addition of a home-based high-intensity knee extension stretching device (Ermi Knee Extensionater) to standard postoperative physical therapy improves recovery of full knee…
- Trial name
- NCT07685561
- Testing
- Standard Physical Therapy, Ermi Knee Extensionater
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Alabama at Birmingham
Carious Teeth, Adaptation
Marginal Evaluation of Zirconia Reinforced Lithium Disilicate Partial Coverage Restoration of Egyptian Posterior Teeth.
Objective: To evaluate the marginal adaptation of the zirconia reinforced lithium disilicate (VITA AMBRIA) glass ceramic Inlay/Onlay compared with lithium disilicate(IPS emax Press) glass ceramic Inlay/Onlay in decayed posterior…
- Trial name
- NCT05281861
- Testing
- Zirconia reinforced Lithium disilicate (Vita Ambria) ceramic onlay restoration, Lithium disilicate (IPS e-max press) ceramic onlay restoration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Restoration, Permanent, Dental Restorations
Clinical Investigation Measuring the Long Term Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.
The aim of this present study is to collect additional data for the post-marketing follow-up of Biodentine™ XP and measure long-term (up to 10 years) performance and safety of the biomaterial in all its indications.
- Conditions
- Dental Restoration, Permanent, Dental Restorations, Endodontic Treatment
- Trial name
- BIOD XP (NCT06955429)
- Testing
- Dental restorative or endodontic treatment requiring Biodentine XP use
- Where
- 8 sites in Belgium, France
- Volunteers
- 275 people
- Sponsor
- Septodont
DENTAL IMPLANTATION
Surface Topography and Color Stability of Implant Supported 3D Printed Provisional Restorations
Patient attending the Outdoor Patient Department of the Department of Prosthodontics at Post Graduate Institute of Dental Sciences, Rohtak will be screened.
- Trial name
- NCT06947070
- Testing
- To evaluate the surface topography and color stability of 3D printing provisional material.
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Tooth Diseases
Clinical Evaluation of Three Different Universal Adhesives in Non-carious Cervical Lesions
The aim of this randomized, controlled prospective clinical trial is to evaluate and compare the performances of three different universal adhesives using a flowable universal composite resin in the restoration of non-caries…
- Trial name
- NCT03415412
- Testing
- Clearfil Univesal Bond, IBond Universal, G-Premio Bond
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Restoration Failure, Postoperative Hypersensitivity
The Effect of Decoupling With Time Technique on the Clinical Performance of Proximal Posterior Composite Restorations
This randomized clinical trial will evaluate whether the decoupling with time technique improves the clinical performance of Class II posterior composite restorations compared with conventional composite restoration techniques.
- Trial name
- DWT (NCT07917572)
- Testing
- Decoupling With Time Technique, Conventional Composite Restoration
- Volunteers
- 50 people
- Sponsor
- Cairo University
Suicidal Behaviour Disorder
Prevention of Suicidal Behavior Through the VIGILANS Protocol: the Restoration of Social Connection Hypothesis
The World Health Organization (WHO) estimates, with 800,000 annual deaths, that suicide is the second leading cause of death in people aged 10 to 44 and thus recognizes suicide prevention as a public health priority.
- Trial name
- RECONEX (NCT05227183)
- Testing
- The virtual version of the Social stress task : V-TSST
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Mitral Valve Disease
EXPLORE MRace (BR): Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant
An early feasibility study to evaluate the safety and feasibility of the MRace Implant and Delivery System to treat severe mitral regurgitation and to gather preliminary data on its performance thereby providing guidance for…
- Trial name
- EXPLORE MRace (NCT06113354)
- Testing
- Transcatheter mitral valve repair (MRace Implant and Delivery System)
- Where
- 2 sites in Brazil
- Volunteers
- 10 people
- Sponsor
- Polares Medical SA
Geographic Atrophy
Restoration of Central Vision With the PRIMA System in Patients With Atrophic AMD
The objective of this study is to evaluate the efficacy and safety of the PRIMA System in patients with atrophic AMD. Eligible subjects will be implanted with the PRIMA Implant.
- Trial name
- PRIMAvera (NCT04676854)
- Testing
- PRIMA Bionic Vision System
- Where
- 21 sites in France, Germany and 4 more
- Volunteers
- 38 people
- Sponsor
- Science Corporation
Erectile Dysfunction
IT Matters: The Erectile Restoration Registry
The objective of the It MATTERS registry is to collect Real-World Data (RWD) to monitor the safe and effective use of commercially available Boston Scientific Corporation (BSC) penile prostheses
- Trial name
- NCT04200937
- Testing
- Tactra Malleable, Spectra™ Concealable Penile Prothesis, AMS Ambicor™ Inflatable Penile Prosthesis
- Where
- 25 sites in United States, China and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Coxarthrosis
Comparison of the Restoration of Hip Biomechanical Parameters by CT Measurement Between the 3 Surgical Techniques: RSA/Minihip/THA - Hip Replacement: 3D Planning
The study will analyze hip biomechanical parameters using EOS radiographic measurements pre- and post-operatively (3 months) and post-operatively (3 months) CT scans after total hip replacement (THR), neck-preserving THR of the…
- Trial name
- HIP3D (NCT06272422)
- Testing
- hip arthroplasty
- Where
- France
- Volunteers
- 165 people
- Sponsor
- University Hospital, Lille
Metal Ceramic Restorations, Gingival Health
A Retrospective Study on Long-Term Technical Complications of Single Metal-Ceramic Crowns With a Supplementary Questionnaire Survey
This observational study aims to evaluate the long-term clinical outcomes and biological complications associated with metal-ceramic crowns.
- Trial name
- NCT07828509
- Testing
- Metal-Ceramic dental single crown
- Where
- Latvia
- Volunteers
- 79 people
- Sponsor
- Riga Stradins University
CAD-CAM, Prospective Study
Clinical Evaluation of Additive and Subtractive Onlay Restorations
The goal of this clinical trial is to learn whether onlay restorations produced by additive manufacturing [three-dimensional (3D) printing] and subtractive manufacturing [Computer-Aided Design/Computer-Aided Manufacturing…
- Conditions
- CAD-CAM, Prospective Study, 3D Printing, Clinical Assessment
- Trial name
- CIP-ONLAY (NCT07195201)
- Testing
- 3D Printed Onlay Restoration, CAD/CAM Onlay Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Ayse Tugba Erturk Avunduk
Spinal Cord Injuries
Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury
The purpose of this study is to assess the efficacy of non-invasive (transcutaneous) closed-loop electrical spinal cord stimulation for recovery of upper limb function (Aim 1) and spasticity (Aim 2) following spinal cord injury.
- Trial name
- NCT05267951
- Testing
- Open-loop Stimulation, Close-loop Stimulation, Functional Task Practice
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Dental Caries Extending Into Dentin, Root Caries
Root Caries Excavation with Air Water/powder Prophylaxis Device for ART Restorations
The main objective of this RCT is to compare the efficacy of a powder/water jet prophylaxis device and conventional hand excavation in excavating root surface caries, with regard to restoration survival/success in older adults.
- Trial name
- ART-AIRFLOW (NCT04822246)
- Testing
- Control: Hand instrumentation for caries excavation, Intervention 1: EMS Airflow device for caries excavation, Intervention 2: Hand excavation + EMS Airflow device for caries excavation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Deep Carious Lesions
Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions.
This study will evaluate the clinical and radiographic performance of resin composite restoration after utilized a grape seed extract as dentin biomodification in vital teeth with deep occlusal carious lesions (ICDAS 5-6) after…
- Trial name
- GSE (NCT06780527)
- Testing
- 15% Grape seed extract as dentin pretreatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Primary Molar Restoration, Dental Restorations in Children
Parent Satisfaction With Zirconia, Bioflx, and 3D-Printed Crowns for Primary Molars
This study will compare parent satisfaction with three different types of dental crowns used to restore primary (baby) molars in children: zirconia crowns, Bioflx crowns, and 3D-printed crowns.
- Trial name
- NCT07672470
- Testing
- Zirconia crown, Bioflx crown, 3D printed crown
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Delta University for Science and Technology
Atrial Fibrillation (AF), Paroxysmal AF
Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration
The objective of this clinical investigation is to evaluate the feasibility, safety, and effectiveness of a concomitant procedure involving the Volt PFA System and Amulet 2 device in patients indicated for both AF ablation and…
- Conditions
- Atrial Fibrillation (AF), Paroxysmal AF, Persistent Atrial Fibrillation
- Trial name
- CLEAR (NCT07523620)
- Testing
- PVI Ablation, Left Atrial Appendage Occluder Implant
- Where
- 16 sites in Belgium, Czechia and 8 more
- Volunteers
- 240 people
- Sponsor
- Abbott Medical Devices
Prosthesis User
Clinical Performance of 3D-Printed Resin and Zirconia Implant Restorations
This randomized controlled clinical trial evaluates the clinical performance of 3D-printed resin restorations compared with milled monolithic zirconia in implant-supported single crowns and short-span fixed partial dentures…
- Trial name
- NCT07522671
- Testing
- 3D-Printed Resin Restoration (CROWNTEC)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University