Clinical trials: Restraint, Physical
Axial Spondyloarthritis
A Post-Marketing-Observational Study (PMOS) to Determine the Effectiveness of Combined Adalimumab Treatment and Active Supervised Training in Patients With Axial Spondyloarthritis (axSpA)
This study is a non-interventional, longitudinal and non-confirmatory study to compare an active supervised training (AST) with standard of care (SOC) physiotherapy in patients with axial spondyloarthritis and stable response to…
- Trial name
- Treat & Train (NCT03258814)
- Testing
- Active Supervised Training (AST), Standard of Care (SOC) Physiotherapy
- Where
- 6 sites in Germany
- Volunteers
- 17 people
- Sponsor
- AbbVie
Obesity, Childhood, Overweight and Obesity
First Heroes: Engaging Fathers in the First 1000 Days
The First Heroes study plans to influence weight and health trajectories, modify disease risk, and improve health care services for mother-father-infant triads from racial/ethnic minority and health disparity populations.
- Conditions
- Obesity, Childhood, Overweight and Obesity, Social Determinants of Health, Physical Activity
- Trial name
- First Heroes (NCT04477577)
- Testing
- New Parent Intervention, Safety Control
- Where
- United States
- Volunteers
- 657 people
- Sponsor
- Massachusetts General Hospital
Sedentary Behavior, Aging
A Trial of Habit Formation Theory for Exercise in Older Adults
This personalized trial will evaluate the effects of five behavioral change techniques (BCTs) described in Habit Formation Theory (Goal setting, Action Planning, Self-Monitoring, Behavioral Practice/Rehearsal and Habit Formation)…
- Conditions
- Sedentary Behavior, Aging, Activity, Motor, Behavior, Health
- Trial name
- NCT04869644
- Testing
- Goal setting, Action Planning, Self-monitoring of behavior
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Caregivers, Parents
Self-Management in Parents of Technology-Dependent Children
Parent caregivers of children with chronic conditions who require life-saving technology such as mechanical ventilation or feeding tubes must maintain a high level of vigilance 24 hours a day, 7 days a week.
- Conditions
- Caregivers, Parents, Self-Management, Chronic Illnesses, Multiple
- Trial name
- NCT04105244
- Testing
- Resourcefulness Training©
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Inactivity
Web-based Physical Activity Intervention for Latinas
This renewal builds upon our successful culturally adapted PA intervention for Latinas (Pasos Hacia La Salud, R01CA159954) and expands its focus to the critical area of maintenance of behavior change.
- Trial name
- NCT03491592
- Testing
- Enhanced Physical Activity Intervention, Original Physical Activity Intervention
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Brown University
Aging, Diabetes Mellitus, Type 2
Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults
Semaglutide is a medication approved by the US Food and Drug Administration (FDA) as an antihyperglycemic (a drug that reduces glucoses in those with diabetes) and for weight management.
- Conditions
- Aging, Diabetes Mellitus, Type 2, PreDiabetes, Overweight and Obesity
- Trial name
- NCT05786521
- Testing
- Semaglutide Injectable Product, Lifestyle Counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Fibromyalgia
Lifestyle Physical Activity to Reduce Pain and Fatigue in Adults With Fibromyalgia
The purpose of this study is to determine the effect of 3 months of daily, 30-minute lifestyle physical activity on pain and fatigue in inactive adults with fibromyalgia (FM).
- Trial name
- NCT00383084
- Testing
- Lifestyle physical activity (LPA), Fibromyalgia education
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Johns Hopkins University
Physical Deconditioning
Shifting Rehabilitation Paradigms in Skilled Nursing Facilities
This study seeks to improve rehabilitation methods for restoring physical function with skilled nursing facility care. More specifically, this study is designed to evaluate the effectiveness of an intensive therapeutic…
- Trial name
- NCT02927171
- Testing
- IntenSive Therapeutic Rehabilitation for Older Skilled Nursing Home Residents
- Where
- 3 sites in United States
- Volunteers
- 104 people
- Sponsor
- VA Office of Research and Development
COPD, Emphysema
The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD
COPD currently afflicts 24 million US residents; the prevalence of COPD is high among Veterans. Persons with COPD have significant functional disability as a result of the disease.
- Conditions
- COPD, Emphysema, Chronic Bronchitis
- Trial name
- WEB (NCT02099799)
- Testing
- Pedometer and Website
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Disease, Type 2 Diabetes
Physical Health in Midlife: Influences of Adversity and Relationships Over Time
The purpose of this study is to determine the effects of individual characteristics, life stresses, and relationships over time on psychosocial outcomes (e.g. marriage, parenting, work) and physical health
- Trial name
- NCT01853332
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Beth Israel Deaconess Medical Center
Pediatric Obesity
Inspiratory Muscle Rehabilitation in Children With Obesity
This is a single-center, randomized, SHAM-controlled, parallel assignment, double-masked, interventional trial among children aged 8-17 years (not yet 18 years old) of age with obesity (n=30), recruited from the Duke Healthy…
- Trial name
- BREATHE Fit (NCT05412134)
- Testing
- Pro2 - 75% of participant's MIP, Pro2 - 15% of participant's MIP
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Duke University
Vestibular Disorder, Balance; Distorted
Individualized Vestibular Rehabilitation for Elderly With Self-Management and Gaming Elements
The aim of this study is to test whether when using the Vestibular Rehabilitation App older patients perform rehabilitation in a similar manner as when directly instructed by a clinician.
- Conditions
- Vestibular Disorder, Balance; Distorted, Vestibular Diseases
- Trial name
- NCT05436067
- Testing
- Vestibular rehabilitation app, Traditional Physical Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- CFD Research Corporation
Acute Respiratory Failure
Novel Arm Restraint in the Intensive Care Unit
The goal of this pilot is to evaluate a novel restraint device in 8 older mechanically ventilated patients to demonstrate that 1) the revised novel restraint prototype is safe and 2) a future randomized controlled trial (RCT) is…
- Trial name
- NCT03621475
- Testing
- Novel restraint
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Vermont
Pulmonary Disease, Chronic Obstructive
Assessment of Physical Functioning and Handling of Spiolto Respimat in Patients With COPD (OTIVACTO)
The primary objective of this Non Interventional Study is to measure changes in physical functioning, a surrogate for physical activity and exercise capacity, in COPD patients on treatment with Spiolto® Respimat® in routine daily…
- Trial name
- NCT02720757
- Testing
- Spiolto Respimat
- Where
- 6 sites in Belgium, Denmark and 4 more
- Volunteers
- 132 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Arterial Hypertension
Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension.
The primary objective of this study is to evaluate the effect of selexipag on the physical activity of patients with pulmonary arterial hypertension (PAH) in their daily life, by using a wearable wrist device (actigraph).
- Trial name
- TRACE (NCT03078907)
- Testing
- Selexipag
- Where
- 39 sites in United States, Austria and 8 more
- Volunteers
- 108 people
- Sponsor
- Actelion
Disability Physical
Pilot Testing a New Pregnancy Decision Making Tool for Women With Physical Disabilities
The purpose of this project is to develop, and pilot test a decision-making tool that is tailored for women with physical disabilities to support those women in making a decision about whether or not a pregnancy is right given…
- Trial name
- NCT04651114
- Testing
- Decision-making tool
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Michigan
Osteoarthritis
Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP)
This is a multi-phase study that will develop and test an osteoarthritis (OA) primary care Physical activity Care Pathway (OA-PCP), a scalable intervention that includes: 1) a practical process for physical inactivity screening…
- Trial name
- NCT03780400
- Testing
- Osteoarthritis Physical Activity Care Pathway
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP), Oral Appliance and Physical Exercise in the Obstructive Sleep Apnea
Introduction: It is unclear whether exercise training with or without Continuous Positive Airway Pressure (CPAP) and Oral Appliance (OA) is more effective in reducing symptoms of Obstructive Sleep Apnea (OSA) than treatment…
- Trial name
- NCT01289392
- Testing
- Continuous Positive Airway Pressure (CPAP), Oral Appliance (OA), Physical Exercise
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Cardiovascular Diseases, Cardiovascular Risk Factor
Cooking for Health Optimization With Patients
Cooking for Health Optimization with Patients (CHOP) is the first known multi-site prospective cohort study with a nested Bayesian adaptive randomized trial in the preventive cardiology field of culinary medicine.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Nutrition Disorders, Diabetes
- Trial name
- CHOP (NCT03443635)
- Testing
- Treatment
- Where
- United States
- Volunteers
- 7,192 people, healthy volunteers welcome
- Sponsor
- Tulane University
Knee Arthroplasty
The Energize! Study for Adults With Knee Replacement
The purpose is to examine the effects of an online physical activity program on moderate to vigorous intensity physical activity, pain, and physical function in adults with knee replacement at 3 months (post-intervention) and 6…
- Trial name
- NCT06096727
- Testing
- Energize!
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of South Carolina