Clinical trials: Resuscitation
Pancreaticoduodenectomy
The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy
The Whipple operation is a complex surgical procedure involving the removal of the head of the pancreas, bile duct, and a portion of the intestine (duodenum) that is performed for patients who have cancer or some other condition…
- Trial name
- NCT01428050
- Testing
- 3% NaCl Solution, Lactated Ringers Solution
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- Thomas Jefferson University
Septic Shock
Fluid Resuscitation for Suspected Sepsis in Paediatric Emergency Departments
With 25.2 million children affected and 3.4 million deaths in 2017, paediatric sepsis is the leading cause of under-five mortality worldwide and has recently been described as "significant global health threat" by the World…
- Trial name
- FRESSPED (NCT05066464)
- Testing
- Fluid Resuscitation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Traumatic Haemorrhagic Shock
An Observational Pilot Study of the Effects of Traumatic Haemorrhagic Shock and Resuscitation on the Microcirculation
Haemorrhage following major trauma is an important preventable cause of death. Those patients who survive may have a prolonged period of debility caused by failure of key body organs.
- Trial name
- MICROSHOCK (NCT02111109)
- Testing
- Side Stream Dark Field Microscopy
- Where
- 3 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- King's College Hospital NHS Trust
Endotracheal Tube Cuff Pressure
Comparison of the Predictions of ETTcP With Pilot Balloon Palpation Among Anaesthesia Residents in Different Years
In routine practice, pressure is often attempted to be adjusted by palpation of the cuff pilot balloon of the endotracheal tube.
- Trial name
- ETTcP (NCT05013658)
- Testing
- pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Kocaeli University
Ventilation Therapy, PEEP, Occult
PEEP vs. ZEEP in Out-of-Hospital-Cardiac-Arrest
Out-of-hospital cardiac arrest (OHCA) remains a major cause of mortality, with low survival probabilities to hospital discharge.
- Conditions
- Ventilation Therapy, PEEP, Occult, CPR, Cardiac Arrest (CA)
- Trial name
- PerAVent (NCT06836830)
- Testing
- PEEP 5 mbar, ZEEP 0 mbar
- Where
- 3 sites in Germany
- Volunteers
- 600 people
- Sponsor
- Muehlenkreiskliniken, MKK
COVID-19, Hypoxic Respiratory Failure
Almitrine and COVID-19 Related Hypoxemia
In severe COVID-19 pulmonary failure, the profound hypoxemia is mainly related to pulmonary vasodilation with altered hypoxic pulmonary vasoconstriction (HPV).
- Trial name
- NCT04380727
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Central Hospital, Nancy, France
Cardiac Arrest
Vienna Near-Infrared Spectroscopy in Cardiac Arrest Study (VINIRSCA)
Measurement of Near-Infrared Spectroscopy (NIRS) during and after out-of-hospital cardiac arrest (OHCA) in the city of Vienna and the tertiary university hospital of the Medical University of Vienna, Austria.
- Trial name
- VINIRSCA (NCT04778488)
- Testing
- Near-Infrared-Spectroscopy (NIRS)
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Medical University of Vienna
Preterm Infant, Birth, Preterm
Aeration, Breathing, Clamping Study 3
Delayed cord clamping (DCC) in preterm infants results in a decrease in mortality and a trend towards fewer intraventricular haemorrhages.
- Trial name
- ABC3 (NCT03808051)
- Testing
- Physiological-based cord clamping, Time-based cord clamping
- Where
- 10 sites in Netherlands
- Volunteers
- 689 people
- Sponsor
- Leiden University Medical Center
Sepsis Syndrome
Blood Gases Versus Lactate Clearance as an Indicator of Initial Resuscitation in Septic Patients: Comparative Study
This perspective blind randomized single center study was designed to assess central venous and arterial gases level including P(v-a)CO2/C(a-v)O2 ratio and P(v-a)CO2 difference against lactate clearance as an indicator of initial…
- Trial name
- NCT05049941
- Testing
- lactat and blood gases
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Minia University
Out-of-hospital Cardiac Arrest
Evaluation of Out-of-Hospital Cardiac Arrest Recognition by Non-physicians Dispatchers in a French Emergency Dispatch Call Center
The purpose of this study is to measure an improvement in the detection rate of cardiac arrest (CA) in the Dispatch Center as a result of debriefings and repeated trainings for non-medical operators who receive emergency calls.
- Trial name
- OCAR (NCT01992419)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Fire Brigade Of Paris Emergency Medicine Dept
Cardiac Arrest, Simulation of Physical Illness
CPR Surface Choice on Chest Compression Quality
The objective of our randomized simulation study on mannequins with a population of Basic Life Support students is to compare the quality of chest compressions, taking depth as the main variable, in two simulated scenarios of…
- Trial name
- NCT06406101
- Testing
- Floor, Bed
- Where
- Spain
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Cardiopulmonary Resuscitation, Cardiac Arrest
Physical Workload Identify in Chest Compression Position Using Surface Electromyogram
The chest compression depth decreases over time after starting continuous chest compression due to the rescuers' fatigue. The investigators hypothesized that the frequency parameters from surface electromyogram from each muscle…
- Trial name
- NCT02088879
- Testing
- chest compression with kneeling position, chest compression with standing position
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Cardiac Arrest, Sudden Cardiac Arrest
Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation
Specific Aim #1: To determine if levels of CoQ10 are low post-cardiac arrest (CA). We will perform a prospective trial with the primary endpoint of describing the prevalence of low serum CoQ10 levels.
- Trial name
- NCT01319110
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Beth Israel Deaconess Medical Center
Resuscitation, Chest Compression
How to Learn Cardiopulmonary Resuscitation
the aim of the study is to evaluate two methods of teaching cardiopulmonary resuscitation in the context of chest compression quality.
- Conditions
- Resuscitation, Chest Compression, Quality
- Trial name
- NCT04039997
- Testing
- CPRMeter, Manual chest compression
- Where
- Poland
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Lazarski University
Shock, Hyopvolemia
Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients by Sonographic Evaluation Before and After Resuscitation.
The aim of this study is to evaluate correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED by sonographic evaluation before and after resuscitation.
- Trial name
- NCT07264374
- Testing
- Ultrasound assesment of FV,IJV and IVC collabsibillity indecis
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pregnancy, Cardiac Arrest
Influence of the Method of Alleviation of Aorto-Caval Compression on the Trans-Hepatic Ultrasound-Assessed Inferior Vena Cava Diameter In Pregnant Patients
Cardiac arrest during pregnancy is rare but may result in poor maternal and fetal outcome. Because of its rare occurrence and ethical issues this topic is not very well studied and many questions pertaining to maternal…
- Trial name
- NCT01982513
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Out-of-hospital Cardiac Arrest (OHCA), Emergency Medical Services
Telemedicine-Assisted vs Conventional Telephone Instruction in Cardiopulmonary Resuscitation
Out-of-hospital cardiac arrest (OHCA) is a life-threatening emergency where early cardiopulmonary resuscitation (CPR) by bystanders can significantly improve survival.
- Trial name
- TACTIC (NCT07546474)
- Testing
- Telemedicine-Assisted CPR (TA-CPR), Dispatcher-Assisted CPR (DA-CPR)
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Siriraj Hospital
Premature Infant, Extremely Low Birth Weight
Time to Accurate Heart Rate on Neonatal Outcomes
The goal of this trial is to compare the time to first heart rate displayed for iRes Warmer with ResusView and using iRes Warmer without ResusView when used in the resuscitation (e.g.
- Conditions
- Premature Infant, Extremely Low Birth Weight, Extreme Prematurity
- Trial name
- GE-EKG (NCT04587934)
- Testing
- iRes Warmer with ResusView, iRes Warmer without ResusView
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Sharp HealthCare
Cardiac Arrest, Cardiopulmonary Arrest
ECMELLA vs. ECMO on 30-day Mortality
This international, multicenter cohort study aims to investigate outcomes after treatment with extracorporeal cardiopulmonary resuscitation (eCPR) during cardiac arrest.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Extracorporeal Membrane Oxygenation Complication, Cardiogenic Shock
- Trial name
- NCT05175898
- Testing
- VA-ECMO, ECMELLA
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Critical Illness
Code Status Video in the Intensive Care Unit: Video Assisted Patient Education
This is a single-center, randomized control trial of a code status video as an educational tool in the intensive care unit. Subjects are stratified by patient or surrogate and are randomized to either watch an educational video…
- Trial name
- NCT01610076
- Testing
- Code Status Video
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Mayo Clinic