Clinical trials: Resuscitations
Severe Burns, Fluid Resuscitation
Fluid Resuscitation in Burn Patients
Balanced solutions with low chloride concentration could represent an alternative to high chloride concentration solutions. Such balanced solutions contain other acid as buffers (i.e. acetate and/or gluconate).
- Trial name
- CARE (NCT03118362)
- Testing
- Plasmalyte, Ringer lactate
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
eFast Diagnosis Performance in Guiding First Aid Resuscitation and Hemostasis
eFast Diagnosis Performance in Guiding First Aid Resuscitation
A lesion work-up associating clinical examination, extended focused ultrasound (eFAST including abdominal ultrasound [right upper, left upper, and suprapubic quadrant], bilateral anterior and lateral pleuropulmonary ultrasound…
- Trial name
- eFAST Decision (NCT03699670)
- Where
- France
- Volunteers
- 510 people
- Sponsor
- University Hospital, Grenoble
Cardiac Arrest, Cardiopulmonary Resuscitation
Generative AI and Gamified Simulation-Based Train-the-Trainer Basic Life Support Training for High School Teachers in Vietnam
The goal of this randomized controlled trial is to learn whether adding generative artificial intelligence (AI) feedback, gamified practice and a structured Train-the-Trainer component to a one-day simulation-based Basic Life…
- Trial name
- NCT07898891
- Testing
- Generative AI and Gamified Simulation-Based Train-the-Trainer BLS Programme, Conventional Instructor-Led Simulation-Based BLS Training
- Where
- 2 sites in Thailand, Vietnam
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Eastern International University
Neonatal Disorder, Asphyxia Neonatorum
Early or Late Cord Clamping in the Depressed Neonate
This study evaluates the hypothesis that delayed compared to early umbilical cord clamping will improve neonatal transition in terms of circulation and breathing during resuscitation.
- Trial name
- NepCordIII (NCT02727517)
- Testing
- Early (≤ 60 seconds) cord clamping, Delayed (≥ 180 seconds) cord clamping
- Where
- Nepal
- Volunteers
- 90 people
- Sponsor
- Uppsala University
Cardiac Arrest, Cardiopulmonary Resuscitation
Consolidating Tools for Outcomes in Resuscitation
In-hospital pediatric cardiac arrest is an important public health problem affecting almost 6000 children a year in the United States.
- Conditions
- Cardiac Arrest, Cardiopulmonary Resuscitation, Simulation, Education
- Trial name
- CONTOUR (NCT02676024)
- Testing
- Knowledge-based cognitive aid, Cognitive aids with roles defined (CARD), Integrated cognitive aids
- Where
- 2 sites in Canada
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Cardiac Arrest
Prehospital Resuscitation Intranasal Cooling Effects Seen in MRI of the Brain After Cardiac Arrest
Therapeutic hypothermia improves the neurologically-intact survival rates in those patients resuscitated out-of-hospital from ventricular fibrillation. Cooling as early as possible might be beneficial to those victims.
- Trial name
- COOLCAMRI (NCT02179060)
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- Tampere University Hospital
Post-Resuscitation Syndrome, Critical Illness
Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest
This retrospective observational cohort study aims to identify early predictors of short- and mid-term mortality in adult patients who achieved return of spontaneous circulation (ROSC) after cardiac arrest.
- Conditions
- Post-Resuscitation Syndrome, Critical Illness, Cardiac Arrest, Hypoxic-Ischemic Encephalopathy
- Trial name
- PROM-ROSC (NCT07020091)
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Ahmet Düzgün
Sepsis
Resuscitation Failure, Oxidative Stress, and Necroptosis as Mortality Predictor in Septic Patient
Resuscitation failure, oxidative stress and necroptosis were able to predict mortality in septic patient
- Trial name
- NCT04169412
- Testing
- Blood Collection
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Universitas Sriwijaya
Arterial Hypotension, Shock
Cerebral Circulation in Critically Ill Children
The principal purpose of this study is to describe the changes in cerebral circulation (assessed by transcranial ultrasound) and oxygenation (assessed by Near InfraRed spectroscopy, NIRS) during resuscitation for hemodynamic…
- Conditions
- Arterial Hypotension, Shock, Cerebral Lesion
- Trial name
- CIRCU-REAPED (NCT03731104)
- Testing
- Near InfraRed Spectroscopy assessment, Transcranial Doppler Ultrasound assessment, Cardiac output assessment
- Where
- 3 sites in France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Premature Birth
Order Effects of Prematurity Outcome Data
Women recruited from the internet were put in a hypothetical situation of being in labor at 22 weeks of pregnancy, and presented with information in the form of pictographs about survival and disability of babies born at this…
- Trial name
- NCT04269616
- Testing
- Order of pictographs provided to participants, Level of description in survival pictograph
- Where
- United States
- Volunteers
- 839 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Cardiac Arrest, Sudden Cardiac Death
Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest
More than 300,000 Americans experience out-of-hospital cardiac arrest annually, with overall survival rates averaging less than 5%.
- Trial name
- NCT01325870
- Testing
- ACD-CPR, ITPR, S-CPR
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Advanced Circulatory Systems
Maternal, Pediatric Care Emergencies
Does Simulation Scenario Execution Improve Acute Care Skills and Confidence Related to Maternal and Pediatric Care Emergencies?
In Uganda and many countries in Sub-Saharan Africa, health providers have minimal training and intermittent opportunity to maintain skills in managing delivery complications and acute newborn and pediatric conditions.
- Trial name
- SimForLife (NCT03258073)
- Testing
- Medical simulation using scenario execution
- Where
- Uganda
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Cardiac Arrest, Out-Of-Hospital, Hypotension
Cardiac Arrest - Ultrasound Detection of Occult Perfusion
The goal of this study is to describe the population of patients presenting after out of hospital cardiac arrest with occult perfusion, defined as a patient without a palpable pulse but with some evidence of pulsatile arterial…
- Trial name
- NCT07897370
- Where
- 8 sites in United States
- Volunteers
- 1,400 people
- Sponsor
- University of Massachusetts, Worcester
Disseminated Intravascular Coagulation (DIC), Reanimation
EARLY DIAGNOSIS OF SEPTIC DIC
Disseminated Intravascular Coagulation is a severe complication of septic shock, associated with high mortality, whose diagnosis relies on complex scores that are rarely used in practice.
- Conditions
- Disseminated Intravascular Coagulation (DIC), Reanimation, Septic Shock
- Trial name
- EASY-DIC (NCT07630415)
- Where
- France
- Volunteers
- 492 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiopulmonary Resuscitation
The Impact of Integration of Ultrasound on CPR Quality - A Video Review Study
High-quality cardiopulmonary resuscitation (CPR) is essential for return of spontaneous circulation (ROSC) in patients with cardiac arrest.
- Trial name
- NCT03695536
- Testing
- ultrasound use during resuscitation
- Where
- 2 sites in Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Hypothermia, Cardiac Arrest
Therapeutic Hypothermia With Propofol in Survival and Neurological Prognoses After Cardiac Arrest
Therapeutic hypothermia has been proven to significantly improve the survival and neurological prognoses in patients resuscitated from cardiac arrest.
- Trial name
- NCT02367755
- Testing
- Propofol, Lorazepam
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Intensive Care
Crystalloid Versus Hydroxyethyl Starch Trials
The aim of this study is to determine whether patients in the Intensive Care Unit who receive fluid resuscitation with either hydroxyethyl starch (a synthetic colloid solution) or saline (a salt solution), have an increased rate…
- Trial name
- CHEST (NCT00935168)
- Testing
- 6% Hydroxy-ethyl starch (130/0.4), Saline
- Where
- Australia
- Volunteers
- 7,000 people
- Sponsor
- The George Institute
Cardiac Arrest
The ICU-Resuscitation Project (ICU-RESUS)
Pediatric cardiac arrest affects thousands of hospitalized children each year. High quality cardiopulmonary resuscitation (CPR) saves lives, but is difficult to achieve.
- Trial name
- ICU-RESUS (NCT02837497)
- Testing
- ICU-RESUS CPR Improvement Bundle
- Where
- United States
- Volunteers
- 1,127 people
- Sponsor
- Children's Hospital of Philadelphia
SIRS, Cytokine Storm
Cytokine Hemoadsorption in ECMO Patients
Cytokine hemoadsorption is a novel therapy used to improve outcome in critically ill patients with a dysregulated cytokine response and hemodynamic instability.
- Conditions
- SIRS, Cytokine Storm, Cardiogenic Shock, Cardiac Arrest
- Trial name
- NCT04901338
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University Medical Centre Ljubljana
Hypoxia
Comparison of Two Pulse Oximeters in Delivery Room
Time to stable reading of oxygen saturation at the delivery room will be compared between two different devices.
- Trial name
- NCT02704585
- Testing
- Nellcor, Masimo
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.