Clinical trials: Resuscitations
Cardio Respiratory Arrest
Effectiveness of a Network of Trained Volunteers Automatically Activated, on the Reduction of the Start Time of Cardiopulmonary Resuscitation Maneuvers. Study Protocol.
Background Cardiorespiratory arrest (CRA) is a health emergency with high mortality. Mortality could depends on the start time of cardiopulmonary resuscitation (CPR) maneuvers (and the quality of its performance) and the use of…
- Trial name
- Smartwatch (NCT03828305)
- Testing
- Training and creation of the Network-CPR, Control Group
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cost Analysis, Length of ICU Stay
An Artificial Intelligence Model for Intensive Care Length of Stay, Neurological Outcome and Costs Estimation After Cardiopulmonary Resuscitation: a Cohort Study.
The study aims to overview patients registered to Bezmialem Vakıf University Hospital Intensive Care Unit after successive cardiac arrest resuscitation from October 2010 to September 2025.
- Conditions
- Cost Analysis, Length of ICU Stay, Neurological Outcome
- Trial name
- NCT07210866
- Testing
- no physical or medical interventions
- Volunteers
- 5,000 people
- Sponsor
- Bezmialem Vakif University
Airway Aspiration, Cardiopulmonary Arrest
The Impact of Soiled Airway Management on CPR Quality
Regurgitation is an adverse event common during cardiopulmonary resuscitation (CPR) and occurs in 20%-32% of patients experiencing out-of-hospital cardiac arrest (OHCA).
- Trial name
- NCT05278923
- Testing
- SALAD simulation device
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Liver Transplantation
co2 Gap and co2/o2 Ratio in Liver Transplant Patients
finding surrogate to co to trace the effect of preload challenge would make the test more applicable without the need of advanced hemodynamic monitors,suggested that co2 gap can be used to detect FR after mini fluid challenge and…
- Trial name
- co2gap (NCT03374579)
- Testing
- Fluid challenge
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Out-Of-Hospital Cardiac Arrest, In-hospital Cardiac Arrest
RIAC - Registro Italiano Arresti Cardiaci (Italian Registry of Cardiac Arrest)
RIAC - An Observational, Prospective, Multi-centre, Study of Epidemiology, Treatment, and Outcome of Cardiac Arrest in Italy.
- Trial name
- RIAC (NCT03220269)
- Testing
- Out-of-hospital cardiac arrest (OHCA), In-hospital cardiac arrest (IHCA)
- Where
- Italy
- Volunteers
- 8,000 people
- Sponsor
- Italian Resuscitation Council
Sudden Cardiac Death, Ventricular Fibrillation
LifeVest Post-CABG Registry
This is a multi-center prospective registry of patients with an ejection fraction (EF) ≤ 35% following coronary artery bypass graft (CABG) surgery in order to test the hypothesis that wearable defibrillators (WD) will decrease…
- Conditions
- Sudden Cardiac Death, Ventricular Fibrillation, Ventricular Tachycardia, Ventricular Dysfunction
- Trial name
- NCT01448005
- Testing
- wearable defibrillator (LifeVest)
- Where
- 5 sites in United States
- Volunteers
- 69 people
- Sponsor
- Zoll Medical Corporation
Shock, Septic
Protocolized Reduction of Non-resuscitation Fluids vs Usual Care in Septic Shock Feasibility Trial
The objectives of this feasibility trial are to assess the efficacy and feasibility of methods and procedures of a protocol purposed to compare a reduction of administration of non-resuscitation fluids to usual care in patients…
- Trial name
- NCT05249088
- Testing
- Protocolised reduction of non-resuscitation fluids, Usual care
- Where
- 8 sites in Sweden
- Volunteers
- 98 people
- Sponsor
- Region Skane
Cardiac Arrest, Out-Of-Hospital
Validity of ICU Clinician's Appraisal of Proportionality in CPR
The VICAP-CPR study investigates whether doctors and nurses working in Intensive Care can determine neurological outcome and future quality of life after six months in patients treated for cardiac arrest outside the hospital…
- Trial name
- VICAP-CPR (NCT07026773)
- Where
- 9 sites in Austria, Belgium and 6 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Basic Cardiac Life Support, Cardiopulmonary Resuscitation
The Effect of T-CPR on the Quality of CPR and AED Use
The purpose of the study is to examine the effect of telephone assistance and standardized basic life support courses on the quality of cardiopulmonary resuscitation (CPR) and the use of automated external defibrillator (AED).
- Trial name
- NCT03690102
- Testing
- T-CPR, ERC standardized BLS course
- Where
- Denmark
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Septic Shock, Severe Sepsis
Early Use of Norepinephrine in Septic Shock Resuscitation
Current septic shock guideline recommends fluid resuscitation as the first treatment. Vasopressors, including norepinephrine is recommended to start after achieve adequate fluid therapy.
- Trial name
- CENSER (NCT01945983)
- Testing
- Early norepinephrine
- Where
- Thailand
- Volunteers
- 310 people
- Sponsor
- Mahidol University
Heart Arrest, Ventricular Fibrillation
AED Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named "One Shock Per Minute"
The aim of the trial is to evaluate a new AED algorithm that proposes a new timeline between the time devoted to administer a defibrillation shock, and the time devoted to chest compressions.
- Trial name
- DEFI2005 (NCT00139542)
- Testing
- One shock per minute AED protocol, Guidelines 2000 AED protocol
- Where
- France
- Volunteers
- 5,107 people
- Sponsor
- Fire Brigade Of Paris Emergency Medicine Dept
Invasive Mechanical Ventilation, Ventilator-Induced Lung Injury
Effects of Large Tidal Volumes Despite Minimal Inspiratory Support in Spontaneously Ventilated Intubated Resuscitation Patients. Pathophysiological Exploratory Study.
Some ICU ventilated patients might present with large tidal volume despite very low or inexistant presser support. Patient-Self Inflicted Lung Injury (P-SILI) might appear related with large alveolar stretch an distension.
- Conditions
- Invasive Mechanical Ventilation, Ventilator-Induced Lung Injury, Patient-Self Inflicted Lung Injury, Encephalopathy
- Trial name
- InLarge (NCT05056961)
- Testing
- Multiparametric mesurements
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Survival to Discharge With Good Neurologic Outcome Among in Hospital Cardiac Arrest Patients
Therapeutic Outcomes of In-Hospital Resuscitation of Patients Admitted to the Internal Medicine Wards
In-hospital cardiac arrest is a common phenomenon associated with high mortality rates. In the United States, 290,000 cases of in-hospital cardiac arrest among adult patients occur annually (1).
- Trial name
- NCT07899645
- Volunteers
- 2,000 people
- Sponsor
- Meir Medical Center
Extracorporeal Membrane Oxygenation, Cardiopulmonary Resuscitation
Cross-sectional Survey of Zhejiang ECMO Application
Extracorporeal lung oxygenation (ECMO) was first used in neonates in the 1970s and is now widely used to treat adult patients with intractable shock and respiratory failure who have failed various types of conventional life…
- Conditions
- Extracorporeal Membrane Oxygenation, Cardiopulmonary Resuscitation, Epidemiology
- Trial name
- NCT04979325
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Severe Influenza, Intensive Care (ICU)
Early Corticosteroids in Severe Influenza Pneumonia
This is a Phase III, multicentre, randomized, controlled, double-blind, superiority trial aiming to evaluate the efficacy of dexamethasone versus placebo in patients admitted to intensive care or intermediate care with influenza…
- Conditions
- Severe Influenza, Intensive Care (ICU), Reanimation, Infectious Diseases
- Trial name
- ECSIP (NCT07786662)
- Testing
- Dexametasone
- Where
- 48 sites in France
- Volunteers
- 544 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Severe Thermal Injury, Greater Than 20% TBSA
Vitamin C for Severe Thermal Injuries
Animal and human data have supported the notion that administration of large doses of Vitamin C has beneficial effects on those subjects suffering from large burns.
- Trial name
- NCT01587261
- Testing
- Vitamin C
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Acute Pancreatitis
Aggressive Versus Non-aggressive Goal-directed Fluid Resuscitation in Acute Pancreatitis
WATERFALL is an investigator-initiated international multicenter open-label randomized clinical trial comparing aggressive versus moderate fluid resuscitation in acute pancreatitis.
- Trial name
- WATERFALL (NCT04381169)
- Testing
- Lactated Ringer Solution
- Where
- 2 sites in Spain
- Volunteers
- 249 people
- Sponsor
- Enrique de-Madaria
Sepsis, Shock
Fluid Management and Individualized Resuscitation in Sepsis
The goal of this clinical trial is to find out if a personalized treatment approach can improve care for people with sepsis in the emergency department (ED).
- Conditions
- Sepsis, Shock, Personalized Medicine, Emergency Medicine
- Trial name
- FLUIDS (NCT07009665)
- Testing
- Personalized SV-guided resuscitation, Standard Care Resuscitation
- Where
- Netherlands
- Volunteers
- 188 people
- Sponsor
- University Medical Center Groningen
Anemia, Sickle Cell
Therapeutic Anticoagulation Strategy for Acute Chest Syndrome
Acute Chest Syndrome (ACS) is a pulmonary complication of sickle cell disease (SCD) representing the leading cause of death and the second cause of hospitalization among adult patients.
- Conditions
- Anemia, Sickle Cell, Acute Chest Syndrome, Low-Molecular-Weight Heparin
- Trial name
- TASC (NCT02580773)
- Testing
- Prophylactic anticoagulation ( INNOHEP®), Curative anticoagulation ( INNOHEP®)
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Arrest, Birth Asphyxia
SI + CC Versus 3:1 C:V Ratio During Neonatal CPR
Research question In newborn infants requiring CPR, does CC superimposed by sustained inflation compared to 3:1 compression to ventilation ratio improves return of spontaneous circulation? Overall objective: CC superimposed by…
- Conditions
- Heart Arrest, Birth Asphyxia, Bradycardia
- Trial name
- SURV1VE (NCT02858583)
- Testing
- CC+SI, 3:1 C:V
- Where
- 4 sites in Austria, Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
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