Clinical trials: Resuscitations
Sepsis, Septic Shock
Personalized Fluid Resuscitation in the Emergency Department: A Pilot Trial
The goal of this pilot clinical trial is to learn if a fluid assessment using non-invasive cardiac output monitoring (NICOM) is helpful for patients with sepsis who have low blood pressure in the Emergency Department (ED).
- Trial name
- FLUID-ED (NCT07779720)
- Testing
- Non-Invasive Cardiac Output Monitoring (NICOM)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Intermountain Health Care, Inc.
Cardiopulmonary Resuscitation
Chest Compression During Resuscitation
The aim of the study was to evaluate the new mechanical chest compression machine LifeLine ARM in healthcare professionals in simulated model of cardiac arrest.
- Trial name
- NCT02703103
- Testing
- Manual chest compressions, ARM chest compressions
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
CABG Surgery
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for CABG Surgery
After obtaining approval from the Institutional Review Board of our institution, written informed consent is obtained from patients undergoing CABG surgery are enrolled in this prospective study and randomly allocated into one of…
- Trial name
- NCT02757027
- Testing
- Intravenous Crystalloid, Intravenous HES
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Sepsis
Early Resuscitation in Paediatric Sepsis Using Inotropes
Septic shock in children still carries substantial mortality and morbidity. While resuscitation with 40-60 mL/kg intravenous fluid boluses remains a cornerstone of initial resuscitation, an increasing body of evidence indicates…
- Trial name
- ANDES-CHILD (NCT06478797)
- Testing
- Fluid, Adrenalin
- Where
- 4 sites in Argentina, Bolivia and 1 more
- Volunteers
- 40 people
- Sponsor
- NATALIA LOPERA MUNERA
Pneumonia
Study of the Characteristics of Acute Mycoplasma Resuscitation: ECRAN-PLASMA Study
The ECRAN-PLASMA study aims to analyze the characteristics of patients with Mycoplasma pneumoniae or Chlamydia pneumoniae pneumonia hospitalized in intensive care units (ICU), continuous monitoring units (USC), or intensive…
- Trial name
- ECRAN-PLASMA (NCT07479355)
- Testing
- Infectious disease epidemiology
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Arrest
In-hospital Cardiopulmonary Resuscitation With Balloon Occlusion of the Descending Aorta
This study will test if a sustained Return of Spontaneous Circulation (ROSC) in patients with cardiac arrest is more frequent when patients receive advanced cardiac life support (ACLS) alone or when they receive ACLS plus a…
- Trial name
- CPReboa (NCT07434726)
- Testing
- resuscitative endovascular occlusion of the aorta (REBOA), Advanced Cardiac Life Support (ACLS)
- Where
- Switzerland
- Volunteers
- 98 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiac Arrest With Successful Resuscitation
Hemodynamic Optimization Through Pleth Variability Index for OHCA
Less than half of the patients suffering from sudden cardiac arrest arrive at the hospital alive. Within these survivors less than half will be discharged alive from the hospital without being severely disabled.
- Trial name
- HemOpt-PVI (NCT03841708)
- Testing
- Pleth variability index, Standard non invasive monitoring
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- Stefano Malinverni, MD
Bleeding, Massive Hemorrhage
Initial Resuscitation With Albumin in Hemorrhagic Shock to Reduce Positive Fluid Balance
This study is designed to evaluate the effect of early albumin transfusion within massive transfusion protocol on fluid balance and reduced requirement of transfusion.
- Conditions
- Bleeding, Massive Hemorrhage, Massive Transfusion Protocol
- Trial name
- ABSOLUTE (NCT06111261)
- Testing
- Albumin solution, Balanced crystalloid solution
- Volunteers
- 36 people
- Sponsor
- Seoul National University Hospital
Cardiac Arrest, Cardiopulmonary Resuscitation
Comparison of Manual Cardiopulmonary Resuscitation (CPR) Versus Automatic CPR Machine During Ambulance Transport.
This is a randomized controlled prospective study which assigned patient to receive manual CPR or automatic CPR machine use. The quality and efficacy between manual CPR and machine CPR will be evaluated.
- Trial name
- NCT00308815
- Testing
- Automatic CPR machine
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest
Vienna Near-Infrared Spectroscopy in Cardiac Arrest Study (VINIRSCA)
Measurement of Near-Infrared Spectroscopy (NIRS) during and after out-of-hospital cardiac arrest (OHCA) in the city of Vienna and the tertiary university hospital of the Medical University of Vienna, Austria.
- Trial name
- VINIRSCA (NCT04778488)
- Testing
- Near-Infrared-Spectroscopy (NIRS)
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Medical University of Vienna
Out-of-hospital Cardiac Arrest
The PulsePoint Randomized Controlled Trial
"Sudden cardiac arrest" occurs when someone's heart stops beating unexpectedly. Each year, more than 45,000 Canadians have a cardiac arrest.
- Trial name
- NCT01746290
- Testing
- PulsePoint notification
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Out-Of-Hospital Cardiac Arrest
International Termination of Resuscitation Practices
Neither the international nor the interregional variation in survival following OHCA is fully understood, but may rely on multiple factors such as: organization of the Emergency Medical Service (EMS) system bystander…
- Trial name
- NCT05029180
- Testing
- Termination of resuscitation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Burn
Colloid Improves Organs Function in Resuscitation of Extensive Burn Patients
The present study was to evaluate the effectiveness of colloid compared with crystalloids for fluid resuscitation in critical burn patients with total burn surface area ≥50%.
- Trial name
- NCT01939613
- Testing
- colloids
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Tang-Du Hospital
Invasive Mechanical Ventilation, Ventilator-Induced Lung Injury
Effects of Large Tidal Volumes Despite Minimal Inspiratory Support in Spontaneously Ventilated Intubated Resuscitation Patients. Pathophysiological Exploratory Study.
Some ICU ventilated patients might present with large tidal volume despite very low or inexistant presser support. Patient-Self Inflicted Lung Injury (P-SILI) might appear related with large alveolar stretch an distension.
- Conditions
- Invasive Mechanical Ventilation, Ventilator-Induced Lung Injury, Patient-Self Inflicted Lung Injury, Encephalopathy
- Trial name
- InLarge (NCT05056961)
- Testing
- Multiparametric mesurements
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Extracorporeal Membrane Oxygenation Complication
Estimation of Glomerular Filtration Flow in Patients of Resuscitation Under Extra-bodily Assistance
The aim of the study will be to evaluate the quality of the GFR estimate of the two estimation equations (CKD-EPI and Cockcroft's formula) against the measured clearance of creatinine, which can be performed routinely in…
- Trial name
- CREA-ECMO (NCT03525483)
- Testing
- Ultrasound for renal resistivity index measurement
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Device Related Sepsis
Novel Device for Rapid Fluid Administration
The aim of the study is to determine if a new device is more effective in fluid administration than devices currently used when resuscitating pediatric patients in septic shock.
- Trial name
- NCT03074682
- Testing
- Lifeflow, Push/Pull, Pressure Bag
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yale University
Cardiac Arrest
Endotracheal Intubation During Resuscitation
We hypothesized that the BONFILS is beneficial for intubation of manikins while performing CPR. In the current study we compared the performance of the BONFILS and the Macintosh laryngoscopes with respect to their effectiveness…
- Trial name
- EIDR (NCT02286323)
- Testing
- Bonfils, Macintosh
- Where
- Poland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Out of Hospital Cardiac Arrest
Artificial Intelligence Cerebral Gray-white Matter Ratio Module Usage in Hsinchu District Hsinchu District Using an Artificial Intelligence Cerebral Gray-white Matter Ratio Module
This study aims to establish an electronic medical record and imaging database for out-of-hospital cardiac arrest (OHCA) patients at NTUH Hsinchu Branch.
- Trial name
- NCT06856018
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Cardiopulmonary Resuscitation, Simulation Training
The Effect of Attention Distractor on the Quality of Chest Compression
The investigators plan to investigate the effect of attention distractor on the quality of chest compression during cardiopulmonary resuscitation.
- Trial name
- NCT03124290
- Testing
- paced auditory serial addition test (PASAT)
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Inje University
Wounds and Injuries
Polytrauma and Resuscitation Impact on Innate Immunity
Major trauma can lead to a dysregulated response to secondary infection. Severe injuries are accompanied by pro- and antiinflammatory changes that affect both adaptive and innate immunity.
- Trial name
- PRIME (NCT06314841)
- Where
- 3 sites in Austria
- Volunteers
- 62 people
- Sponsor
- Ludwig Boltzmann Gesellschaft
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