Clinical trials: Resuscitations
Apnea, Bradycardia
MRSOPA-Drills to Improve Mask Ventilation in the Delivery Room
Establishing breathing after birth is vital for survival and long-term health of premature babies. 10% of all preterm babies fail to breathe after birth and require help with breathing.
- Trial name
- MRSOPA (NCT02375230)
- Testing
- Control group, MR SOPA
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Sepsis, Acute Renal Failure
Inferior Vena Cava Collapsibility and Distensibility Assessment in Critical Care.
This study will help in determining the impact of assessment of Inferior Vena Cava Collapsibility and Distensibility Index (IVC CI and DI) through Point Of Care Ultra Sound (POCUS), for the fluid management of critically ill…
- Conditions
- Sepsis, Acute Renal Failure, Acute Gastroenteritis, Diabetic Ketoacidosis
- Trial name
- NCT06516692
- Testing
- Inferior Vena Cava Collapsibility/distensibility Index (IVC CI/DI) assessment
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Out-of-Hospital Cardiac Arrest, Blood Pressure
Blood Pressure and OXygenation Targets After OHCA
This study compares two blood pressure targets and two oxygenation targets in the post-resuscitation care of comatose out-of-hospital cardiac arrets patients.
- Conditions
- Out-of-Hospital Cardiac Arrest, Blood Pressure, Hemodynamic Instability
- Trial name
- BOX (NCT03141099)
- Testing
- Low normal MAP, High normal MAP, Low normal PaO2.
- Where
- 2 sites in Denmark
- Volunteers
- 802 people
- Sponsor
- Jesper Kjaergaard
Out-of-hospital Cardiac Arrest
Save Hearts in Arizona Registry and Education (SHARE) Project
Evaluation of the impact of bystander CPR, prehospital resuscitation protocols, and hospital post-resuscitation protocols for out-of-hospital cardiac arrest patients in the state of Arizona.
- Trial name
- SHARE (NCT01999036)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- University of Arizona
Septic Shock
Pilot Study for the SQUEEZE Trial
The purpose of the SQUEEZE Trial is to determine which fluid resuscitation strategy results in the best outcomes for children treated for suspected or confirmed septic shock.
- Trial name
- SQUEEZE (NCT01973907)
- Testing
- Fluid Sparing Resuscitation Strategy
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- McMaster Children's Hospital
Corona Virus Infection, Critical Illness
The Change of Critical Patient Managements and Subsequent Influences Under Epidemic of Coronavirus Disease 19 (COVID-19)
In the ER of National Taiwan University Hospital, the critical patients are treated (including tracheal intubation and cardiopulmonary resuscitation) in either resuscitation area or negative pressure isolation rooms based on the…
- Trial name
- NCT04479332
- Testing
- Tracheal intubation and cardiopulmonary resuscitation
- Where
- Taiwan
- Volunteers
- 198 people
- Sponsor
- National Taiwan University Hospital
Virtual Reality, Heart Arrest
Traumatic Cardiac Arrest and Trauma SimVR Training
The goal of this single-center, prospective, randomized, controlled trial is to evaluate the effectiveness of using virtual reality technology to provide learners with skills and knowledge in the management of traumatic cardiac…
- Trial name
- Trauma SimVR (NCT06445764)
- Testing
- e-learning, Virtual reality training
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Circulatory Failure, Cardiac Arrest
Evaluation of Efficacy of the Prototype RPC (Rapid Pulse Confirmation) Device in Detecting Return of Pulsatile Flow in Patients Preparing to Separate From CPB (Cardiopulmonary Bypass)
Effective chest compressions are essential to survival in an arrest patient receiving CPR (cardiopulmonary resuscitation). A challenge in providing effective chest compressions is frequent interruption of compressions.
- Trial name
- NCT04526249
- Testing
- rapid pulse confirmation device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Michael Kyle Ritchie
Cardiac Arrest, Cardiac Arrest Circulatory
Resuscitative TEE Collaborative Registry
The general objective of this study is to evaluate the clinical impact and safety of focused, point-of-care transesophageal echocardiography (TEE) used during the evaluation of critically-ill patients in the emergency and…
- Conditions
- Cardiac Arrest, Cardiac Arrest Circulatory, Cardiac Arrest, Out-Of-Hospital, Shock
- Trial name
- rTEECoRe (NCT04972526)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Pennsylvania
Neonatal Resuscitation, Apnea Neonatal
Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates
Many extremely premature infants require immediate help with breathing after birth. Positive pressure ventilation (PPV) using a device called a T-piece resuscitator is a common method.
- Trial name
- MVP (NCT06849596)
- Testing
- Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 780 people
- Sponsor
- Michelle Baczynski
Hypobaric Hypoxia, Cognitive Deterioration
Effects of Acute Hypobaric Hypoxia Exposure on Neurocognitive Performance of Pre-hospital Emergency Service Providers
The study aims to evaluate the effects of acute hypobaric hypoxia on cognitive performance (H0: cognitive performance at 200 meters above sea level (asl) = cognitive performance at 3000 meters above sea level = cognitive…
- Conditions
- Hypobaric Hypoxia, Cognitive Deterioration, Emergency Medicine, Resuscitation
- Trial name
- NCT04138446
- Testing
- Altitude exposure in climate chamber
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Shock, Septic
Protocolized Reduction of Non-resuscitation Fluids vs Usual Care in Septic Shock Feasibility Trial
The objectives of this feasibility trial are to assess the efficacy and feasibility of methods and procedures of a protocol purposed to compare a reduction of administration of non-resuscitation fluids to usual care in patients…
- Trial name
- NCT05249088
- Testing
- Protocolised reduction of non-resuscitation fluids, Usual care
- Where
- 8 sites in Sweden
- Volunteers
- 98 people
- Sponsor
- Region Skane
Cardiac Arrest With Successful Resuscitation, Hypoxia, Brain
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation
The STEPCARE-trial is a 2x2x2 randomised trial studying patients who have been resuscitated from cardiac arrest and who are comatose.
- Trial name
- STEPCARE (NCT05564754)
- Testing
- Feedback-controlled temperature device, High MAP, Deep sedation
- Where
- 56 sites in Australia, Belgium and 13 more
- Volunteers
- 3,500 people
- Sponsor
- Region Skane
Nonreassuring Fetal Status
Acute Tocolysis With Terbutaline for Suspected Fetal Distress
The trial was to determine the effect of administrating subcutaneous terbutaline prior to emergency caesarean delivery for suspected fetal distress
- Trial name
- NCT05326269
- Testing
- Terbutaline
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Kemaman
Cardiac Arrest, Cardiopulmonary Resuscitation
Evaluation of eCPR Survivors
A cardiac arrest event has severe impact on the patient´s health-related quality of life. Survival of cardiac arrest does not innately translate to favorable quality of life.
- Conditions
- Cardiac Arrest, Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation Complication, Myocardial Infarction
- Trial name
- NCT05339854
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Charite University, Berlin, Germany
Cardiac Arrest With Successful Resuscitation, Hypothermia
Skeletal Muscle Paralysis in Hypothermic Patients After Cardiac Arrest
Mild hypothermia improves neurological outcome after cardiac arrest. Neuromuscular blockers are in use, together with analgesia and sedation, during the cooling process in many centers to prevent shivering.
- Conditions
- Cardiac Arrest With Successful Resuscitation, Hypothermia, Skeletal Muscle Relaxant Overdose
- Trial name
- RELAX (NCT01719770)
- Testing
- rocuronium
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Out-of-Hospital Cardiac Arrest, Death, Sudden, Cardiac
The Use of Mobile Phones in Out of Hospital Cardiac Arrest to Increase Bystander CPR
Death from cardiac disease is one of the most common causes of death in the western world. The majority of these deaths takes place outside hospital as sudden cardiac death.
- Conditions
- Out-of-Hospital Cardiac Arrest, Death, Sudden, Cardiac, Heart Diseases, Ventricular Fibrillation
- Trial name
- RUMBA (NCT01789554)
- Testing
- MLS dispatch for bystander CPR
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Karolinska Institutet
Cirrhosis, Liver, Acute-On-Chronic Liver Failure
20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension
Patients with cirrhosis patients have a high incidence of sepsis which can trigger decompensation and may result in prolonged hospital stay and increased mortality.
- Conditions
- Cirrhosis, Liver, Acute-On-Chronic Liver Failure, Shock, Septic, Shock Hypovolemic
- Trial name
- NCT05441878
- Testing
- 20% albumin, Balanced salt solution
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Oxygen Dependent COPD, Advanced Malignancy
Changing the Paradigm of In-Hospital Cardiopulmonary Resuscitation
Outcomes after in-hospital cardiopulmonary resuscitation (CPR) are very poor, particularly in patients with oxygen dependent chronic obstructive pulmonary disease (COPD) or metastatic cancer.
- Trial name
- NCT01558817
- Testing
- Informed Assent, Informational Brochure
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- University of Vermont
Critical Illness, Fluid Over-load
Effect of Dynamic Arterial Elastance and Assisted Fluid Management Software Guided Resuscitation in Septic Shock: Pilot Study
To investigate the benefit of using the AFM and Eadyn-guided fluid and vasopressor therapy in septic shock resuscitation for mechanically ventilated patients compared with the standard of care.
- Conditions
- Critical Illness, Fluid Over-load, Dynamic Arterial Elastance, Septic Shock
- Trial name
- DAFM shock (NCT06937918)
- Testing
- The AFM and Eadyn - guided resuscitation group, The standard care for septic shock
- Where
- 3 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.