Clinical trials: Resuscitations
Heart Arrest, Cardiac Arrest, Out-Of-Hospital
Synergy of Elevation of the Head and Thorax and REBOA During Out-of-Hospital Cardiac Arrest
Long-term neurological outcome after successful resuscitation of cardiac arrest remains poor, mainly due to cerebral hypoperfusion and severe hypoxic-ischemic brain injuries.
- Conditions
- Heart Arrest, Cardiac Arrest, Out-Of-Hospital, Cardiopulmonary Arrest, Cardiopulmonary Resuscitation
- Trial name
- GRAVITY2 (NCT06537492)
- Testing
- REBOA, Head-Up Cardiopulmonary Resuscitation (AHUP-CPR), Mechanical Chest Compression Device with Active Chest Decompression
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Grenoble
Thrombopenia
Study of Incidence, of Mechanisms and Prognosis of the Thrombopenia From Patients of Reanimation.
About 40 % of the patients in reanimation are thrombopenics and the causes are not well known (reduction in platelet's production, increase in their destruction...).
- Trial name
- NCT00336687
- Where
- France
- Volunteers
- 322 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cardiac Arrest
Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia
The primary objective of the trial is to determine if survival to hospital discharge is improved with early therapeutic administration of a new Captisol-Enabled formulation of IV amiodarone (Nexterone-PM101) compared to placebo.
- Trial name
- ALPS (NCT01401647)
- Testing
- amiodarone, Lidocaine, Normal saline
- Where
- 9 sites in United States, Canada
- Volunteers
- 3,024 people
- Sponsor
- University of Washington
Damage Control, Trauma Abdomen
BIA Guided-fluid Management in Postinjury Open Abdomen
Fluid overload (FO), resulting from high volume fluid therapy, is frequent and contributes to excessive visceral edema, delayed fascial closure, and adverse outcomes among postinjury open abdomen (OA) patients.
- Conditions
- Damage Control, Trauma Abdomen, Acute Compartment Syndrome
- Trial name
- BGFM (NCT03466684)
- Testing
- BIA-guided fluid resuscitation protocol, Traditional fluid resuscitation protocol
- Volunteers
- 140 people
- Sponsor
- Nanjing PLA General Hospital
Cardiac Arrest
Premature Termination of Resuscitation in Survivors of Cardiac Arrest
The study Premature Termination of Resuscitation in Survivors of Cardiac Arrest focuses on using innovative knowledge translation strategies to improve appropriate neuroprognostication for survivors of cardiac arrest and prevent…
- Trial name
- PremaTOR (NCT01472458)
- Testing
- Quality improvement
- Volunteers
- 905 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cardiopulmonary Arrest, Resuscitation
Augmented Reality to Support Cardiopulmonary Resuscitation
A prospective, multicenter, randomized clinical trial in two tertiary pediatric emergency department. It will assess, amongst pediatric healthcare teams, whether the use of augmented reality supportive devices improves adherence…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatric
- Trial name
- NCT06376643
- Testing
- Augmented reality supportive tool, Conventional method (AHA pocket reference card)
- Where
- 2 sites in Canada, Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johan Siebert, MD
Cardiac Arrest
Monitoring of Intubation and Ventilation During Resuscitation
Airway control and ventilation is vital during cardiopulmonary resuscitation (CPR) in cardiac arrest. Endotracheal intubation is the gold standard for airway control, but several studies have shown high rates of unrecognized…
- Trial name
- NCT00204217
- Testing
- endotracheal intubation
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- University of Oslo
CPR Guidelines
Flowchart-Assisted Resuscitation. Standard CPR vs. Chest Compressions Only: What Happened to the Quality?
ABSTRACT Background: More than two thirds of sudden cardiac arrests are witnessed by bystanders. Bystander cardiopulmonary resuscitation (CPR) doubles survival from cardiac arrest.
- Trial name
- NCT02438527
- Testing
- Chart for CPR guidance
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Septic Shock, Fluid Reponsiveness
This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume Overload
Reliability of the LVOT-VTI versus lung ultrasonography for early detection of fluid intolerance during fluid resuscitation of septic patients.
- Trial name
- lvotvti (NCT07797751)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Health Knowledge, Attitudes, Practice
Evaluation of Physiotherapists' Knowledge Level of Cardiopulmonary Resuscitation
This study was planned to determine the physiotherapists' knowledge and qualifications of CPR, their beliefs about the use of CPR in an emergency, and their perception of CPR competence.
- Trial name
- NCT04779073
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Cardiac Arrest, Respiratory Failure
Hospital Airway Resuscitation Trial
The Hospital Airway Resuscitation Trial (HART) is a cluster-randomized, pragmatic trial of advanced airway management with a strategy of first choice supraglottic airway vs.
- Trial name
- HART (NCT05520762)
- Testing
- A strategy of first choice supraglottic airway, A strategy of first choice endotracheal intubation
- Where
- United States
- Volunteers
- 1,083 people
- Sponsor
- Montefiore Medical Center
Respiratory Insufficiency
Incidence and Risk Factors of Extubation Failure in Pediatric Resuscitation
The failure of extubation in pediatric resuscitation is most often described as the need for reintubation within 48 hours after extubation.
- Trial name
- NCT03129802
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Basic Life Support
Early or Late Booster for Basic Life Support?
Attrition of skills after basic life support (BLS) training is common. Psychology studies have established that for basic memory recall tasks, spaced learning strategies improve retention.
- Trial name
- NCT02998723
- Testing
- Early Booster Teaching, Late Booster Teaching
- Where
- Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Infant, Newborn, Diseases, Fetus or Neonate Affected by Cesarean Section
HeartLight: Heart Rate Monitoring for Newborn Resuscitation
This study will compare a newborn heart rate sensor (HeartLight) that is integrated into a hat with other common forms of heart rate monitoring such as electrocardiography (ECG), stethoscope and pulse oximetry (PO) in newborn…
- Conditions
- Infant, Newborn, Diseases, Fetus or Neonate Affected by Cesarean Section, Infant, Premature, Diseases
- Trial name
- HeartLight (NCT02701920)
- Testing
- HeartLight hat, The HeartLight hat with in-built sensor, HeartLight
- Where
- United Kingdom
- Volunteers
- 184 people
- Sponsor
- University of Nottingham
Sepsis, Septic Shock
Personalized Fluid Resuscitation in the Emergency Department: A Pilot Trial
The goal of this pilot clinical trial is to learn if a fluid assessment using non-invasive cardiac output monitoring (NICOM) is helpful for patients with sepsis who have low blood pressure in the Emergency Department (ED).
- Trial name
- FLUID-ED (NCT07779720)
- Testing
- Non-Invasive Cardiac Output Monitoring (NICOM)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Intermountain Health Care, Inc.
Resuscitation
To Compare Predictive Power of End-tidal Carbon Dioxide Between Different Time Line During Resuscitation
To analyze a multi-center observational study database. to select adult non-traumatic in-hospital cardiac arrest. Review and recored end-tidal carbon dioxide in per minute. Arrange them in different time line.
- Trial name
- NCT03345888
- Testing
- predictive power of end-tidal carbon dioxide
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Peking Union Medical College Hospital
Respiratory Distress Syndrome, Newborn, Infant, Newborn
Feasibility of Uninterrupted Infant Respiratory Support Treatment
Feasibility study of a simplified respiratory support system for newborn infants
- Conditions
- Respiratory Distress Syndrome, Newborn, Infant, Newborn, Respiratory Insufficiency Syndrome of Newborn
- Trial name
- FUIRST (NCT04244890)
- Testing
- Uninterrupted CPAP for the first hours of life
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska Institutet
Liver Transplantation
DCN for ECD Livers
The goal of this observational study is to learn whether extended criteria donor livers can be safely transplanted after sequential hypo- and normothermic machine perfusion in recipients requiring a liver transplant for end-stage…
- Trial name
- NCT06804746
- Testing
- DHOPE-COR-NMP
- Where
- 2 sites in Netherlands
- Volunteers
- 143 people
- Sponsor
- Erasmus Medical Center
Decision Making, Resuscitation
Evaluation of a Decision Aid About Life-sustaining Therapies
Introduction: Clinical practice guidelines recommend shared decision making (SDM) to facilitate goals-of-care discussions. This study will train clinicians about how to use a context-adapted decision aid (DA) and SDM to conduct…
- Conditions
- Decision Making, Resuscitation, Intensive Care Unit, Goals-of-care
- Trial name
- NCT04034979
- Testing
- decision aid
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Laval University
Testing, Reality
The Impact of ResuGlove as a Chest Compression Feedback Device
The goal of this simulation-based randomized trial is to assess if the newly proposed ResuGlove can improve the quality of chest compressions during CPR training of laypersons and inexperienced health professionals.
- Trial name
- ResuGlove (NCT05695469)
- Testing
- Smart resuscitation glove (ResuGlove), Traditional CPR
- Where
- Finland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Turku
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