Clinical trials: Retained Products of Conception
Retained Products of Conception
Removal of Intrauterine Retained Products of Conception (RPOC) After Miscarriage Guided by Hysteroscopy Trial. A Randomized Controlled Trial.
Rationale: Elective immediate dilation and curettage (D\&C) for miscarriage is associated with the occurrence of intrauterine adhesions (IUA). IUAs may be associated with subsequent subfertility and premature birth.
- Trial name
- RIGHT (NCT04804332)
- Testing
- Operative hysteroscopy, Expectant management
- Where
- Belgium
- Volunteers
- 244 people
- Sponsor
- University Hospital, Ghent
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Retained Products of Conception
B-HCG Levels in Women Diagnosed With Retained Products of Conception
Retained Products of Conception (RPOC) is a condition where gestational tissue remains in the uterus after birth or after a surgical or medical abortion.
- Trial name
- NCT04917016
- Testing
- Plasma B-HCG levels
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Assaf-Harofeh Medical Center
Retained Products of Conception, Intrauterine Adhesion
Hysteroscopy Assisted Suction Curettage for Early Pregnancy Loss
Retained products of conception (RPOC) and intrauterine adhesions (IUA) may occur following suction curettage for early miscarriage and cause secondary infertility, recurrent pregnancy loss and pregnancy complications.
- Trial name
- NCT04637373
- Testing
- Hysteroscopy
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Abnormal Uterine Bleeding, Postmenopausal Bleeding
Use of Nitrous Oxide During Office Hysteroscopy
The goal of this clinical trial is to assess the use of inhaled nitrous oxide during office hysteroscopy. The main questions it aims to answer are: Does it reduce pain during the procedure? Does it increase the success rate? Does…
- Conditions
- Abnormal Uterine Bleeding, Postmenopausal Bleeding, Endometrial Polyps, Retained Products of Conception
- Trial name
- NCT07074795
- Testing
- Inhalation of Nitrous Oxide (N₂O) during Office Operative Hysteroscopy, inhalation of ambient air during office hysteroscopy
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Maaynei Hayesha Medical Center
Uterine Polyp, Retained Products of Conception
Predictive Factors for Successful Operative Hysteroscopy Using Tissue Removal Device (TruClear System) Without Anesthesia
Background: Small-diameter operative hysteroscopes may allow to perform operative hysteroscopy without general anesthesia in selected patients.
- Trial name
- NCT05722028
- Testing
- hysteroscopy
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Assaf-Harofeh Medical Center
Asherman Syndrome
Efficiency of Intercoat (Oxiplex/AP Gel)in Decreasing Intrauterine Adhesions
This is a prospective single blind randomized controlled pilot study was designed to investigate whether the biological barrier Intercoat (Oxiplex/AP gel) reduces formation of intrauterine adhesions following hysteroscopic…
- Trial name
- NCT01377779
- Testing
- Oxiplex/AP gel, Normal Saline
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Endometrial Polyps, Retained Products of Conception
Impact of Different Saline Pressures During Hysteroscopy on Visibility, Feasibility and Patients' Discomfort
Hysteroscopy is a minimally invasive diagnostic and therapeutic procedure for various intrauterine conditions. It is performed with an optic device while entering liquid media to the uterus to allow visualization.
- Conditions
- Endometrial Polyps, Retained Products of Conception, Lysis of Intrauterine Adhesions, Removal of Retained Intrauterine Device
- Trial name
- NCT06620978
- Testing
- Low pressure: Operative hysteroscopy without anesthesia with normal Saline medium in low pressure.., High pressure: Operative hysteroscopy without anesthesia with normal Saline medium in High pressure.
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Retained Products of Conception Post Abortion
Oral Contraceptive Pills Versus Expectant Management for Retained Pregnancy Products
We speculate that the use of combined oral contraceptives may be a possible solution to promote the management of retained pregnancy products versus expectant management.
- Trial name
- NCT03230825
- Testing
- Oral contraceptive, Expectant management
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Prevenetion of Intrauterine Adhesions by Hyaluronic Acid Gel
Intrauterine Hyaluronic Acid Gel for Prevention of Intrauterine Adhesions
Women undergoing operative hysteroscopy for removal of retained placenta after delivery will be randomized into two groups. 1. study group - immediately after operative hysteroscopy 5 ml hyaluronic acid gel will be injected into…
- Trial name
- NCT04975373
- Testing
- Intrauterine injection of hyaluronic acid
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Barzilai Medical Center
Abortion Induced Complicated
Management of RPOC After Induced Abortion
Randomized trial comparing expectant management and medical management in women diagnosed with retained products of conception after first trimester induced abortion
- Trial name
- RPOC (NCT04685694)
- Testing
- Misoprostol
- Where
- Israel
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Fibroid Uterus, Polyp Uterus
Comparison of Operative Hysteroscopy Performed in the Operating Room Versus Outpatient Settings
This is an observational prospective monocentric study which aims to compare operative hysteroscopies performed in the operating room under general or loco-regional anesthesia and those performed outside the operating room…
- Conditions
- Fibroid Uterus, Polyp Uterus, Retained Products of Conception
- Trial name
- NCT07146659
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Hypervascularized Uterine Retentions
Diagnosis and Management of Enhanced Myometrial Vascularity Associated With Retained Products of Conception
Background: Hypervascularized products of conception remain a topic debated in terms of definitions (ultrasound criteria, need complement by angio MRI) and management. The different uterine vascular lesions are often confused.
- Trial name
- EMV RPOC AVM (NCT04176679)
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Montpellier
Intra-uterine Residua
Non Surgical Management for Uterine Residua After Pregnancy Termination, Abortion or Delivery
The aim of the study is to find out whether conservative treatment - expectant management or medical therapy using misoprostol is beneficial in the case of uterine residua, and which treatment is better.
- Trial name
- NCT01134926
- Testing
- misoprostol
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- HaEmek Medical Center, Israel
Retained Products of Conception, RPOC
A Prospective Multicenter Observational Real-world Study of Retained Products of Conception
The purpose of this study is to explore the optimal treatment strategy for retained products of pregnancy. Compared with surgical treatment, prospectively observe whether drug-assisted expectant management until the right time…
- Trial name
- NCT07421895
- Testing
- Uterine curettage, Expectant care
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Missed Abortion, Incomplete Abortion
The Role of Uterine Artery Doppler Parameters in the Management of Retained Products of Conception.
During the recent decades the need for surgical evacuation of the uterus in early miscarriages and incomplete miscarriages has been questioned.
- Conditions
- Missed Abortion, Incomplete Abortion, Uterine Gestational Residua, Uterine Artery Doppler
- Trial name
- NCT01775917
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Carmel Medical Center
Placenta, Retained, Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage
Management of Large Retained Products of Conception (> 4 cm): Need for an Standardized Procedure.
Collection of relevant data form patients who were treated in the Ghent University Hospital in the context of a placental remnant lager than 4 cm, performing statistical analyzes on the collected data, reviewing the literature on…
- Conditions
- Placenta, Retained, Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage, Placenta; Retention, Fragments, Complicating Puerperium (Delayed Hemorrhage), Pregnancy Related
- Trial name
- NCT04720885
- Testing
- kind of surgery
- Where
- Belgium
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Retained Products of Conception
Intracervical Vasopressin
This randomized study looks at whether using a medicine injected into the cervix of the uterus (intracervical), called vasopressin, helps to achieve better removal of retained products of conception (RPOC).
- Trial name
- NCT07102615
- Testing
- Intracervical injection of Vasopressin, Intracervical Injection of saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Prisma Health-Upstate
Retained Products of Conception
The Efficacy of Auto-cross Linked Hyaluronic Acid Gel in the Prevention of Adhesion Reformation After Hysteroscopic Resection of Retained Products of Conception
Retained product of conception (RPOC) is defined by abnormal trophoblastic persistence or retained placenta inside the uterus cavity after a pregnancy independently of the outcome. Untreated RPOC can compromise future fertility.
- Trial name
- NCT05085067
- Testing
- auto-crossed-linked hyaluronic acid gel
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Spontaneous Abortion, Missed Abortion
Dilation and Curettage Versus Operative Hysteroscopy for Missed Abortion
Randomizedtrial comparing success and complication rates of operative hysteroscopy versus traditional dilation and curettage (D\&C) in the management of first trimester missed abortion.
- Conditions
- Spontaneous Abortion, Missed Abortion, Intrauterine Adhesion, Retained Products of Conception
- Trial name
- NCT04705324
- Testing
- Operative Hysteroscopy, D&C, Operative Hysteroscopy - safety and feasibility
- Where
- Israel
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center