Clinical trials: Retention
Denture Retention
A Study to Investigate Food Occlusion Efficacy of a Denture Adhesive in Denture Wearers
The purpose of this study is to determine the ability of a marketed denture adhesive to restrict food ingress underneath dentures during eating.
- Trial name
- NCT03709810
- Testing
- Marketed Denture Adhesive (Super Poligrip Max Seal), No Adhesive
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- GlaxoSmithKline
Postoperative Urinary Retention
Preoperative Administration of Tamsulosin for Prevention of Post Operative Urinary Retention in Males Undergoing Elective Inguinal Hernia Repair
Double blinded, randomized controlled prospective study looking at 2 preoperative doses of Tamsulosin an alpha-adrenergic blocker in preventing post-operative urinary retention.
- Trial name
- NCT02958878
- Testing
- Tamsulosin
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Gastric Retention, Healthy
Study Determining Gastric-Retentive and Modified Release Properties of Prototype Capsules in Healthy Subjects
To assess how long modified release (MR) memantine hydrochloride prototype capsule formulations stay in the stomach as determined by magnetic resonance imaging (MRI).
- Trial name
- NCT03468543
- Testing
- Memantine Hydrochloride MR Prototype Capsule Formulation A, Memantine Hydrochloride MR Prototype Capsule Formulation B, Memantine Hydrochloride MR Prototype Capsule Formulation C
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Lyndra Inc.
Denture Retention
A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers
The purpose of this study is to evaluate a methodology to determine the ability of a denture adhesive to restrict food ingress underneath dentures during eating.
- Trial name
- NCT03345108
- Testing
- Denture Adhesive Cream (Conventional Application), Denture Adhesive (Continuous Strip Application), No Adhesive
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Alzheimer Disease, Gastric Retention
Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules Containing Memantine Hydrochloride in Healthy Adults
To assess how long memantine hydrochloride (HCl) (50 mg) extended release capsules stay in the stomach as determined by imaging assessment (MRI or abdominal ultrasound).
- Conditions
- Alzheimer Disease, Gastric Retention, Healthy
- Trial name
- NCT03711825
- Testing
- LYN-057, Imaging Assessment (MRI), Imaging Assessment (U/S)
- Where
- Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lyndra Inc.
Gastric Retention, Healthy
Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules in Healthy Adults
To assess how long extended release prototype capsule formulations stay in the stomach as determined by magnetic resonance imaging (MRI).
- Trial name
- NCT03718390
- Testing
- Formulation A, Formulation B, Formulation C
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lyndra Inc.
Urinary Retention, Neurogenic Bladder
Connected Catheter (C2P) Study for Bladder Management
The objective of this study is to evaluate the safety and essential performance of the C2P System in males with neurogenic lower urinary tract dysfunction (NLUTD), both in an acute clinical setting and an extended period of home…
- Trial name
- NCT03626324
- Testing
- C2P
- Where
- 8 sites in United States
- Volunteers
- 27 people
- Sponsor
- Spinal Singularity
Memory Disorders, Age-Related, Retention Disorders, Cognitive
A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory Complaints
The purpose of this study is to determine whether Tanakan® is effective at slowing the progression from memory complaint to dementia of Alzheimer's type.
- Trial name
- NCT00276510
- Testing
- EGb 761® (Tanakan®)
- Where
- 698 sites in France
- Volunteers
- 2,878 people
- Sponsor
- Ipsen
Urinary Bladder, Neurogenic
Connected Catheter Clinical Feasibility Study( CFS)
The objective of this study is to evaluate the safety and essential performance of the Connected Catheter System in males with neurogenic lower urinary tract dysfunction (NLUTD), both in an acute clinical setting, and during and…
- Trial name
- NCT03405285
- Testing
- Connected Catheter
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Spinal Singularity
Denture Retention
A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive
The objective of this study will be to compare bite force (BF) measurements over a 12-hour period of a currently marketed denture adhesive cream based on carbomer technology (test), with a positive control and a negative/no…
- Trial name
- NCT03037307
- Testing
- Test Product, Positive Contol, Negative Control
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress
In this clinical study, an experimental denture adhesive with a precision tip nozzle was tested to evaluate the relative efficacy to reduce the ingress of food under the denture compared to use of no adhesive or a standard…
- Trial name
- NCT02928380
- Testing
- Experimental Denture Adhesive, Reference (Marketed) Denture Adhesive
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
A Bite Force Study Comparing Two New Test Adhesives With Currently Marketed Denture Adhesive
The objective of this 4-treatment, 4-period, randomized, crossover, proof of principle bite force study will be to compare bite force measurements over a 12 hour period across two (test) cream denture adhesives, with a currently…
- Trial name
- NCT02937870
- Testing
- Test Product 1, Test Product 2, Reference Product
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Urinary Retention
Comparison of Two Intermittent Urinary Catheters
This is an unblinded, multi-center, randomized, controlled, cross-over study assessing wheel-chair bound, male user preference and catheter characteristics of two intermittent urinary catheters.
- Trial name
- NCT01284361
- Testing
- 30 cm Intermittent Catheter, 40 cm Intermittent Catheter
- Where
- 4 sites in United States
- Volunteers
- 91 people
- Sponsor
- Hollister Incorporated
Epilepsy
Risk of Urinary Retention With Retigabine
A prospective cohort study of antiepileptic drug (AED) polytherapy-treated epilepsy patients within the HealthCore Integrated Research Database (HIRD) will be conducted.
- Trial name
- NCT01462656
- Testing
- Non-EZG containing AED polytherapy, EZG containing AED polytherapy, Non-EZG AED monotherapy
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Spinal Cord Injury (SCI), Chronic Urinary Retention
Tissue Bonding Cystostomy(TBC)
Spinal Cord Injured [SCI] patients typically cannot "pee". Injury to the spinal cord disrupts the in-coming and out-going brain signals that coordinate bladder sensation and the emptying of bladder.
- Conditions
- Spinal Cord Injury (SCI), Chronic Urinary Retention, Urinary Incontinence
- Trial name
- TBC (NCT01771159)
- Testing
- TBC
- Volunteers
- 10 people
- Sponsor
- Uro-Research, LLC
Memory Disorder, Retention Disorder, Cognitive
Investigation of Memantine in the Treatment of Memory, Concentration or Attention Problems
In this study, memantine will be tested in a new indication: in the treatment of subjective memory, concentration, or attention problems (subjective cognitive impairment) in the absence of dementia.
- Conditions
- Memory Disorder, Retention Disorder, Cognitive, Subjective Cognitive Impairment, Memory, Concentration or Attention Problems
- Trial name
- NCT01261741
- Testing
- Memantine
- Where
- 14 sites in Germany, United Kingdom
- Volunteers
- 299 people
- Sponsor
- Merz Pharmaceuticals GmbH
Urge Incontinence, Urinary Retention
Patient Registry to Study the Tined Lead Used With the InterStim System For Urinary Control
The purpose of this study is assess the long-term safety and effectiveness of the InterStim tined lead using a minimally invasive approach.
- Trial name
- NCT00225966
- Testing
- Device Medtronic InterStim Tined Leads Models 3889 and 3093
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- MedtronicNeuro
Benign Prostatic Hyperplasia (BPH), Urinary Retention
A Study to Determine the Safety and Efficacy of a New Non-invasive Heating Garment to Reduce Urinary Hesitancy
To determine the safety and efficacy of the ThermaRx heating device for the application of controlled low level heat to improve symptoms of LUT dysfunction (hesitancy, urgency).
- Conditions
- Benign Prostatic Hyperplasia (BPH), Urinary Retention, Urinary Hesitancy Intermittent
- Trial name
- NCT00700505
- Testing
- FlowPants(R) Garment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ThermaRx, Inc.
Acute Urinary Retention
Alfuzosin for Treating Acute Urinary Retention
The primary objective of the study is to assess the efficacy of alfuzosin 10mg daily in the return to successful voiding after removal of the catheter following a first episode of acute urinary retention (AUR) in patients…
- Trial name
- NCT00336921
- Testing
- Alfuzosin
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Sanofi
Prostatic Hyperplasia, Acute Urinary Retention
ALFAURUS : A DB Randomized Parallel Group Study of Alfuzosin 10mg OD vs Placebo in the Management of AUR in Patients With a 1st Episode Due to BPH
To assess the efficacy of alfuzosin 10mg OD in the management of acute urinary retention associated with BPH. To assess the safety of alfuzosin in this population and health care consumption.
- Trial name
- NCT00290030
- Testing
- Alfuzosin
- Volunteers
- 800 people
- Sponsor
- Sanofi