Clinical trials: Retention Disorders, Cognitive
Patients With Cognitive Disturbances
Hippocampal Sclerosis and Amnesia Not Due to Alzheimer's Disease
Hippocampal Sclerosis (HS) leads to anterograde amnesia mimicking early Alzheimer's disease (AD) (so called HSA-nonAD). Recent studies showed that (a) the deficit of episodic memory as well as the level of hippocampal atrophy in…
- Trial name
- ShaTau7 (NCT02576821)
- Testing
- Neurological examinations, Neuropsychological examinations, Clinical examinations
- Where
- France
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Breast Cancer Survivors
A Study of Attention and Memory Processes in Breast Cancer Survivors
The purpose of this study is to observe the attention and memory processes in breast cancer survivors. Both cancer survivors and healthy volunteers (who are the same age as the cancer survivors) will participate in this study so…
- Trial name
- NCT04883398
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Memory Impairment
Donepezil Memory Preservation Post ECT
This randomized, placebo-controlled trial will evaluate the use of donepezil compared to placebo to reduce the risk of memory impairment after electroconvulsive therapy (ECT).
- Trial name
- NCT02331771
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Porter Adventist Hospital
Bone Tumor, Cancer of Bone
Endoprosthesis Metal Toxicity Study
The purpose of this research is to investigate whether patients who previously had endoprosthesis surgery experience memory, thinking, or heart problems. It will also help determine how often these problems occur.
- Conditions
- Bone Tumor, Cancer of Bone, Heart Diseases, Cognitive Impairment
- Trial name
- NCT04755140
- Testing
- Questionnaires, Interviews, Blood Test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Memory Lapse
Mindful Attention to Variability in Everyday Memory
Forgetfulness is a common complaint among middle and older adults, with the vast majority of these complaints not rooted in established causes or diagnoses.
- Trial name
- NCT03949868
- Testing
- High Mindfulness, Low Mindfulness, Active control
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Harvard University
Schizophrenia, Schizoaffective Disorder
Brain Health and Exercise in Schizophrenia
To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Poor Memory
- Trial name
- PEHP (NCT01392885)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BC Mental Health and Addictions Research Institute
Impaired Cognition, Geriatric Disorder
The Efficacy of Using Volunteers to Implement a Cognitive Stimulation Program in Two Long-Term Care Homes
Many volunteers visiting seniors make socially-based "friendly visits". This study investigated the efficacy of volunteers making visits focused on stimulating cognition.
- Conditions
- Impaired Cognition, Geriatric Disorder, Learning Disorders, Age-Related Memory Disorders
- Trial name
- VolCogStim (NCT01818778)
- Testing
- Cognitive stimulation program, Standard Friendly Visit
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Queen's University
Dementia, Alzheimer Disease
Our Care Wishes - Dementia
This Our Care Wishes- Dementia pilot study is adapting an existing successful online advance care planning platform to the specific needs of persons living with dementia and shared decision-makers (SDMs) and testing the usability…
- Conditions
- Dementia, Alzheimer Disease, Memory Impairment
- Trial name
- NCT05033262
- Testing
- Our Memory Care Wishes
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep Architecture, Sleep Disorders
Sleep, Cognition and Memory Disorder
The increasing incidence of Alzheimer's disease (AD) and related sleep-disorders with the aging of the population is a major issue of public health. The prevalence of sleep disturbances is about 50% in dementia patients.
- Conditions
- Sleep Architecture, Sleep Disorders, Cognitive Impairment
- Trial name
- SCOAL (NCT01650454)
- Testing
- 2 night polysomnography, battery of neuropsychological tests, virtual reality test
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Mild Cognitive Impairment, Alzheimer Disease
Understanding Brain Mechanisms Involved in Autobiographical Memory
The overall objective of this project is to characterize the spatiotemporal dynamics of brain oscillations underpinning autobiographical memory (ABM) and the modulation of the memory network using non-invasive brain stimulation.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Memory Loss
- Trial name
- NCT05710549
- Testing
- high-density electroencephalography (hdEEG), Transcranial alternating current stimulation (tACS)
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Lucie Bréchet
Memory Disorders, Postmenopausal Symptoms
The Effect of a Multivitamin in the Treatment of Memory Loss in Postmenopausal Women
Complaints about memory loss are very common in women in the menopausal transition period. The effectiveness of estrogen replacement therapy in cognitive improvement is controversial.
- Trial name
- NCT03835325
- Testing
- Cogmax®
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Cognitive Decline, Memory Loss
Effects of Music and Dance on Cognition, Frailty, and Burden in Elderly Caregivers Living in Rural Communities
This research aims to analyze the effects of senior dance on the cognition, frailty, and burden in elderly caregivers of rural communities.
- Conditions
- Cognitive Decline, Memory Loss, Frail Elderly Syndrome, Burden, Dependency
- Trial name
- NCT03068299
- Testing
- Dance, Health care guidance
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Cognitive Impairment, Mild, Cognitive Dysfunction
MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment
This is a randomized, double-blind, placebo-controlled, parallel group study. The use of placebo is appropriate to minimize bias related to treatment expectations of the subject, study partner, and site investigator, as well as…
- Conditions
- Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque, Neurodegenerative Disease, Hereditary
- Trial name
- NCT06177028
- Testing
- Lenalidomide 10 mg
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Aging, Anxiety
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Two hallmarks of both healthy aging and age-related disease are 1) memory and navigational deficits, particularly in orienting towards goal locations and planning how to navigate to them, and 2) increased susceptibility to stress…
- Conditions
- Aging, Anxiety, Memory Impairment
- Trial name
- NCT03896529
- Testing
- Anticipatory psychological stress
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Alzheimer Disease, Neurodegenerative Diseases
Memory Deterioration in Alzheimer Disease
Semantic AD
- Conditions
- Alzheimer Disease, Neurodegenerative Diseases, Magnetic Resonance Imaging, Memory Impairment
- Trial name
- MemAD (NCT07118137)
- Testing
- 7T MRI, EEG, Blood samples
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Memory Loss
Dietary Flavanols and Dentate Gyrus Function
to assess the effect of differing amounts of a cocoa-derived dietary flavanol (epicatechin ) on dentate gyrus function and corresponding cognitive function
- Trial name
- NCT02312310
- Testing
- Cocoa Flavanol
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Fluid Retention, Sodium Retention
The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress
The primary purpose of the proposed study is to evaluate the effects of a topical sodium bicarbonate lotion (PR Lotion, AMP Human, Park City, UT) on measures of hydration status and fluid balance in humans when exposed to the…
- Conditions
- Fluid Retention, Sodium Retention, Heat Stress, Dehydration (Physiology)
- Trial name
- AMP2 (NCT05092854)
- Testing
- PR Lotion - AMP Human Performance, AminoVital - Rapid Recovery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Memory Disorders, Neurocognitive Disorders
Creation of an Ecological Tool Assessing Episodic Memory in Geriatrics
In this study the participants can be recruited via scheduled consultation and external institutions (associations, senior club..).
- Trial name
- ECOTESTGER (NCT05668598)
- Testing
- ecological MAI test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Lens
Mild Cognitive Impairment
Water-based Activity to Enhance Recall in Veterans
This two-year study will evaluate the feasibility of an exercise training augmentation for cognitive training intervention to improve memory performance in Veterans with a diagnosis of amnestic Mild Cognitive Impairment (aMCI).
- Trial name
- WATER-VET (NCT02614092)
- Testing
- Water-based Activity + Cognitive Training
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Lack of Satiety, Dietary Modification
Breakfast Consumption in Preschoolers: Satiety, Diet Quality and Memory
One important factor determining school performance is the consumption of breakfast. While research has shown that older children perform better in school after consuming breakfast, there are little data for preschool-age…
- Conditions
- Lack of Satiety, Dietary Modification, Memory Deficits, Obesity
- Trial name
- NCT02122224
- Testing
- High fiber breakfast, High Protein Breakfast, High Protein/High Fiber Breakfast
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Purdue University