Clinical trials: Retina Detachment
Exudative Retinal Detachment, Uveal Melanoma
TTT Versus TTT and Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy
Proton beam therapy is a safe irradiation modality for choroidal melanoma. But often after irradiation the exudation increases resulting in an exudative retinal detachment requiring vitreoretinal surgery.
- Trial name
- NCT02379000
- Testing
- Triamcinolone Acetonide, Transpupillary thermotherapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Glaucoma Eye, Macular Degeneration
Retinal Oxygenation Estimation Trial With Mantis Photonics Hyperspectral Camera
An explorative study of the Mantis Photonics hyperspectral camera for retinal imaging and estimation of retinal oxygenation. Primary objective: To evaluate the performance of the hyperspectral camera for non-invasive retinal…
- Conditions
- Glaucoma Eye, Macular Degeneration, Macula Abnormality, Retinal Detachment
- Trial name
- NCT05566626
- Testing
- Hyperspectral retinal image, Mydriacyl Ophthalmic Product
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mantis Photonics AB
Retinal Detachment
Subconjunctiva Bupivacaine as Analgesia in Intravitreal Silicone Oil Removal
The study aimed to investigate the effectivity of bupivacaine 0,5% as post-operative analgesia in intravitreal silicone evacutaion surgery
- Trial name
- NCT03046719
- Testing
- Bupivacaine 0,5%, NaCl 0,9%
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Indonesia
Vitreoretinal Detachment, Vitreo-Retinal Adhesion
Microarchitecture of Vitreoretinal Contact
Investigation of the vitreoretinal contact microarchitecture in the macular and paramacular zones of the human retina.
- Trial name
- NCT04802889
- Testing
- scanning electron microscopy
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Proliferative Vitreoretinopathy
Triamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative Vitreoretinopathy
To evaluate the effect of triamcinolone acetonide in silicone-filled eyes on the outcome of surgery for PVR.
- Trial name
- NCT00373282
- Testing
- Triamcinolone acetonide
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Retinal Detachment
Proof of Concept - Digital Electro-optical Surgical Platform as Replacement for Operational Microscopes
Evaluate the use of Elbit's digital electro-optical systems for generating detailed high quality video imaging during surgery, and thus improving the surgeon's visualization, performance and outcome.
- Trial name
- NCT02715388
- Testing
- GlasScope Surgical Microscope
- Where
- Israel
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Elbit Systems LTD
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Retinal Detachment
Randomized Controlled Trial of LUtein as a Novel Neuroprotective Adjunctive Therapy to Improve Visual Outcome of Rhegmatogenous Retinal Detachment (LUNAR Study)
Retinal detachment is a major cause of blindness, particularly among contemporary Asian populations due to the high prevalence of myopia. Without timely treatment, retinal detachment invariably results in blindness.
- Trial name
- NCT03932305
- Testing
- Lutein
- Volunteers
- 110 people
- Sponsor
- Singapore National Eye Centre
Macular Holes, Retinal Detachment
Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery
The purpose of this study is to evaluate the effects of a structured exercise program on musculoskeletal pain of patients in face-down posture after retinal surgery.
- Trial name
- NCT04535622
- Testing
- A structured exercise
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Samsung Medical Center
Proliferative Vitreoretinopathy, Retinal Detachment
The Silicone Study
To compare, through a randomized, multicenter surgical trial, the postoperative tamponade effectiveness of intraocular silicone oil with that of an intraocular long-acting gas (initially sulfur hexafluoride [SF 6 ], later…
- Trial name
- NCT00000140
- Testing
- Perfluoropropane, Sulfur Hexafluoride, Silicone Oil
- Sponsor
- National Eye Institute (NEI)
Rhegmatogenous Macula-off Retinal Detachment
Safety and Efficacy of Brimonidine Tartrate Posterior Segment Drug Delivery System in Improving Visual Function
This study will evaluate the efficacy and safety of the Brimo PS DDS® Applicator System (200 μg and 400 μg brimonidine tartrate) on visual function in patients with previous rhegmatogenous macula-off retinal detachment.
- Trial name
- NCT00972374
- Testing
- 400 ug Brimonidine Implant, 200 ug Brimonidine Implant
- Where
- 6 sites in United States, India and 4 more
- Volunteers
- 44 people
- Sponsor
- Allergan
Conjunctivitis, Glaucoma
Feasibility Study and Preliminary Application Study on Iris OCTA
All participants will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. The main outcomes are iris blood flow density and vascular density.
- Conditions
- Conjunctivitis, Glaucoma, Myopia, Diabetic Retinopathy
- Trial name
- NCT03631108
- Testing
- OCTA (ZEISS)
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Retinal Detachment, Metamorphopsia
Retinal Displacement After Pneumatic Versus Vitrectomy for Retinal Detachment (ALIGN)
This is a prospective cohort study, comparing the functional outcomes and the retinal displacement rates between two techniques for primary rhegmatogenous retinal detachment repair: Pars Plana Vitrectomy (PPV) and Pneumatic…
- Conditions
- Retinal Detachment, Metamorphopsia, Aniseikonia
- Trial name
- ALIGN (NCT04089033)
- Testing
- Pneumatic Retinopexy, Pars Plana Vitrectomy
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Unity Health Toronto
Retinal Detachment
The Posturing After Retinal Detachment (Post RD) Trial
A randomised controlled trial to evaluate the effect of face-down posturing on retinal displacement and distortion following retinal detachment repair.
- Trial name
- NCT02748538
- Volunteers
- 262 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
AMD - Age-Related Macular Degeneration
Comparison of the Sensibility of Swept Source Optical Coherence Tomography Devices in the Detection of Neovascularisation in Large Pigment Epithelium Detachments
The goal of this observational study is to compare swept source optical coherence tomography devices ability to detect macular neovascularisation when there is a large pigment epithelium detachment higher than 250 microns
- Trial name
- NCT07143526
- Testing
- Optical Coherence Tomography Angiography (OCT-A)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University of Trieste
Retina; Detachment, Rhegmatogenous
Head Positioning After Retina Detachment Repair
This study aims to determine if one day post-operative prone head positioning can be as good as seven days post-operative prone head positioning in patients with retinal detachments with inferior retinal breaks after pars that…
- Trial name
- NCT03714503
- Testing
- Retina re-attachment repair using C3F8 gas tamponade
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Retinal Detachment Rhegmatogenous
Emulsification of Different Viscosity Silicone Oil After Complicated Retinal Detachment Surgery
Silicone oil has been used as a surgical tool in complicated retinal detachment surgery. There are some complications occurring in pars plana vitrectomy with silicone oil tamponade.
- Trial name
- NCT02988583
- Testing
- Surgery using low viscosity silicone oil, Surgery using high viscosity silicone oil
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Khon Kaen University
Vitreous Injury, Retinal Detachment
Pars Plana Vitrecromy in Patients Aged 85 Years and Above
We reviewed the records of 120 consecutive patients (male and female), aged 85 years and above, who underwent pars plana vitrecromy in the Tel Aviv Medical Center during the years 01/01/2006 - 31/12/2013, and were followed by…
- Conditions
- Vitreous Injury, Retinal Detachment, Age Related Macular Degeneration
- Trial name
- PPV (NCT03222362)
- Testing
- Surgery
- Volunteers
- 120 people
- Sponsor
- Tel Aviv Medical Center
Rhegmatogenous Retinal Detachment
Combined Laser-surgical Technology of RRD Treatment
Purpose: to assess the efficacy and safety of combined laser-surgical technology of RRD treatment
- Trial name
- NCT04403750
- Testing
- Combined laser-surgical technology of RRD treatment
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Retinal Detachment
Spring Loaded Syringe for Active Silicon Oil Extraction
The aim of our study is to compare between two techniques used for active SOR. The outcomes include efficiency and safety. Patients with silicon filled eyes and prepared for SOR 540 eyes of 505 patients (one eye in 470 patients…
- Trial name
- NCT07363889
- Testing
- Vitrectomy machine, Spring loaded syringe
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University