Clinical trials: Retina Detachment
Retinal Detachment, Proliferative Vitreoretinopathy
Bevacizumab Against Recurrent Retinal Detachment
The investigators hypothesize that bevacizumab instilled into the vitreous after primary retinal detachment surgery will reduce the formation of proliferative vitreoretinopathy and subsequent retinal re-detachment.
- Trial name
- BEARRD (NCT02192970)
- Testing
- Bevacizumab
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Wisconsin, Madison
Retinal Detachment, Rhegmatogenous Retinal Detachment
Lamivudine and Plasma Markers of Inflammation in Retinal Detachment
The goal of this clinical trial is to test whether an oral medication (lamivudine) enters the eye and reduces blood markers of inflammation in people who undergo retinal detachment surgery (pars plana vitrectomy).
- Trial name
- NCT06056596
- Testing
- Lamivudine 300 MG
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison
Retinal Detachment
Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery.
Purpose: to assess the efficacy and safety of double tamponade versus silicone oil tamponade. Design: parallel-group study with balanced [1:1] stratified block randomization.
- Trial name
- NCT01959568
- Testing
- Vitrectomy and tamponade
- Where
- Russia
- Volunteers
- 290 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Rhegmatogenous Retinal Detachment, High-risk for Proliferative Vitreoretinopathy (PVR)
Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment.
This study investigates the effectiveness of a simple treatment to prevent proliferative vitreoretinopathy (PVR). Intraoperative intravitreal 5-fluorouracil (5-FU) and low molecular weight heparin (LMWH) is used as a prophylactic…
- Trial name
- PRIVENT (NCT02834559)
- Testing
- 5-fluorouracil and low molecular weight heparin
- Where
- 13 sites in Germany
- Volunteers
- 326 people
- Sponsor
- Universitätsklinikum Köln
Rhegmatogenous Retinal Detachment, Primary Vitrectomy
Primary Vitrectomy With Endolaser or Encircling Band for Rhegmatogenous Retinal Detachment
Comparing primary PPV with 360° endolaser photocoagulation with primary PPV with an encircling band for patients with RRDs.
- Conditions
- Rhegmatogenous Retinal Detachment, Primary Vitrectomy, Encircling Band, Endolaser Treatment
- Trial name
- NCT00757536
- Testing
- Encircling Band, Endolaser Photocoagulation
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Retinal Detachment
Flexibility, Efficacy, and Safety of a Foldable Capsular Vitreous Body in the Treatment of Severe Retinal Detachment
The purpose of this study is to determine the feasibility, primary safety and efficacy of foldable capsular vitreous body (FCVB) in the treatment of retinal detachment, based on the multi-center clinical trial.
- Trial name
- NCT01261533
- Testing
- foldable capsular vitreous body(FCVB)
- Where
- 9 sites in China
- Volunteers
- 122 people
- Sponsor
- GuangZhou WeiShiBo Biotechnology Co., ltd
Retinal Detachment Rhegmatogenous
Use of Preoperative Gas in Eyes With Macula-off Rhegmatogenous Retinal Detachment (RRD)
The purpose of this study is to evaluate whether a preoperative intraocular gas injection improves visual outcomes in patients with a macula-off rhegmatogenous retinal detachment (RRD).
- Trial name
- NCT07855770
- Testing
- Intravitreal 100% C3F8 Injection, Pars plana vitrectomy or pars plana vitrectomy with scleral buckle
- Where
- 2 sites in United States
- Volunteers
- 190 people
- Sponsor
- Wills Eye
Macular Hole Retinal Detachment, Myopic Traction Maculopathy
Vitrectomy and Scleral Shortening for Macular Hole Retinal Detachment or Myopic Traction Maculopathy
The medical records of 16 eyes of 16 patients with macular hole retinal detachment or myopic traction maculopathy who received viterctomy including internal limiting membrane peeling and scleral shorting surgery were reviewed.
- Trial name
- NCT02528045
- Testing
- Vitrectomy with scleral shortening
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Kyorin University
Cataract, Vitreous Hemorrhage
Surgical Procedure Efficiency Evaluation stuDy
The purpose of this real-world evidence study is to compare surgical procedure times for UNITY® VCS and CONSTELLATION® Vision System.
- Conditions
- Cataract, Vitreous Hemorrhage, Retinal Detachment, Macular Pucker
- Trial name
- NCT07228091
- Testing
- UNITY VCS, CONSTELLATION
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Alcon Research
Retinal Detachment
Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment
Retinal detachment occurs when fluid separates the retina (a thin, light sensing tissue) from its usual attachment at the back of the eye.
- Trial name
- NOMAD (NCT06587945)
- Testing
- Nicotinamide Riboside, Vitrectomy and Gas tamponade
- Where
- 5 sites in Australia
- Volunteers
- 144 people
- Sponsor
- Center for Eye Research Australia
Retinitis Pigmentosa, Maculopathy, Age Related
Bimodal and Coaxial High Resolution Ophtalmic Imaging
The knowledge of the pathogenesis of retinal affections, a major cause of blindness, has greatly benefited from recent advances in retinal imaging.
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema
- Trial name
- AOSLO-OCT (NCT04620876)
- Testing
- Bimodal high resolution imaging of the retina
- Where
- France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Rhegmatogenous Retinal Detachment
Foldable Capsular Scleral Buckling Versus Vitrectomy in Medium-complex Rhegmatogenous Retinal Detachment Treatment
The objective of the study is to evaluate: 1. Safety and efficacy of a novel foldable capsular scleral buckle (FCSB) in scleral buckling for primary rhegmatogenous retinal detachment (RRD) of medium complexity. 2.
- Trial name
- FCSB (NCT06610786)
- Testing
- foldable capsular scleral buckling, vitrectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Rhegmatogenous Retinal Detachment
Axial Length Change in Eyes Treated by Silicone Sponge Scleral Buckling
All existing medical literatue regarding axial length (AL) changes after scleral buckling surgery for retinal detachment, descibes changes after solid silicone buckling.
- Trial name
- NCT01647373
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
PArs Plana Vitrectomy, Retinal Detachment
Quantification of Silicone Oil Emulsification After Pars Plana Vitrectomy
silicone oil tamponade removal after previous injection of complicated retinal detachment can be achieved with active suction followed by triple air-fluid exchange or prolonged lavage of the vitreous chamber to remove…
- Conditions
- PArs Plana Vitrectomy, Retinal Detachment, Silicone Oil Droplets on Intraocular Lens
- Trial name
- NCT04774146
- Testing
- pars plana vitrectomy
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Ospedale Policlinico San Martino
Diabetic Retinopathy, Retinal Detachment
Diabetic Retinopathy Vitrectomy Study (DRVS)
To compare two therapies, early vitrectomy and conventional management, for recent severe vitreous hemorrhage secondary to diabetic retinopathy.
- Conditions
- Diabetic Retinopathy, Retinal Detachment, Vitreous Hemorrhage
- Trial name
- NCT00000154
- Testing
- Vitrectomy
- Sponsor
- National Eye Institute (NEI)
Retinal Detachment
A Study in Subjects With Retinal Detachment
The purpose of this trial is to access the tolerability of INS37217 Intravitreal Injection when administered intravitreally in subjects with macula-on or macula-off rhegmatogenous retinal detachment (RRD).
- Trial name
- NCT00210067
- Testing
- denufosol tetrasodium (INS37217) Intravitreal Injection
- Volunteers
- 14 people
- Sponsor
- Merck Sharp & Dohme LLC
Rhegmatogenous Retinal Detachment
Combined Laser-surgical Technology of RRD Treatment
Purpose: to assess the efficacy and safety of combined laser-surgical technology of RRD treatment
- Trial name
- NCT04403750
- Testing
- Combined laser-surgical technology of RRD treatment
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Epiretinal Membranes, Retinal Detachment
Subjective Pain Scoring for Subtenonal Anesthesia During Vitrectomy
Subtenonal anesthesia is a well-known technique of local anesthesia for patients undergoing pars plana vitrectomies. It was described to be efficient with respect to anesthesia of the eye and it showed less risks compared to…
- Conditions
- Epiretinal Membranes, Retinal Detachment, Full Thickness Macular Hole
- Trial name
- NCT06830070
- Testing
- subjective pain score assessment
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Retinal Detachment
Impact of ILM Peeling in RRD/ I-Peel
Retinal detachment is associated with a substantial risk of re-detachment in 10-20% and to the formation of secondary epiretinal membranes in up to 15%.
- Trial name
- I-Peel (NCT04767555)
- Testing
- ILM (inner limiting membrane) peeling
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Berner Augenklinik
Rhegmatogenous Macula-off Retinal Detachment
Corneal Endothelial Cell Changes In Silicon Filled Eye
The aim of this study is to evaluate corneal endothelial cell changes after pars plana vitrectomy in Rhegmatogenous Retinal detachment , compare the results using different silicon oil viscositites , and assess whether these…
- Trial name
- Endothelium (NCT07418606)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University