Clinical trials: Retina Disease
Retina Disease
Modified P200TE Data Collection
Images will be collected on the modified P200TE
- Trial name
- NCT07796230
- Testing
- imaging device
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Epiretinal Membrane, Dry Age Related Macular Degeneration
(CIRRUS-2023-1) CLINICAL CLIN Assessment of PathFinder 1.0 on the CIRRUS 6000 and the CIRRUS 5000
This study will measure how well PathFinder 1.0 detects retinal abnormalities on macular cube OCT B-scans by assessing its sensitivity and specificity.
- Conditions
- Epiretinal Membrane, Dry Age Related Macular Degeneration, Macular Abnormalities, Retina Disease
- Trial name
- NCT07680244
- Testing
- PathFinder 1.0 on CIRRUS HD-OCT
- Where
- 6 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec-Dublin CoCe
Glaucoma Associated With Other Ocular Disorders, Retina Disorder
AOSLO Imaging for the Study of Cellular Alterations in Retinal Neurodegeneration
Primary objective: Acquisition and analysis of images for non-medical purposes using the MONA IV system, an adaptive-optics-corrected scanning ophthalmoscope.
- Trial name
- RETION (NCT07725055)
- Testing
- MONA Imaging System
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Cardiovascular Diseases, Retina; Change
Imaging of Retinochoroidal Vasculature in Patients Being Assessed for Cardiovascular Disease
This study aims to determine whether changes in retinal vasculature seen on SS-OCTA can be correlated to degree of cardiovascular disease as measured by carotid duplex ultrasonography.
- Trial name
- NCT05082402
- Testing
- Swept Source Optical Coherence Tomography Angiography
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Optical Coherence Tomography of Retina, Alzheimer Disease
Comparative Study of High Performance Low-Cost Optical Coherence Tomography (Stage 1B, 2 and 3)
The purpose of this study is to complete performance testing of our custom optical coherence tomography (OCT) device to verify it can deliver retinal images of similar quality to a commercial OCT device.
- Trial name
- NCT07425106
- Testing
- retinal imaging with low-cost OCT-a/LCI device
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Duke University
Optical Coherence Tomography, Optical Coherence Tomography Angiography
Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers
Alzheimer disease is hard, long and expensive to diagnose. In order to help the clinician, a new biomarker in Alzheimer disease seems to be very useful.
- Conditions
- Optical Coherence Tomography, Optical Coherence Tomography Angiography, Retinal Thickening, Alzheimer Disease
- Trial name
- RETEVAL (NCT04794634)
- Testing
- Optical coherence tomography (OCT), Optical coherence tomograpohy angiography (OCTA)
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Myopia, Refractive Errors
Effect of Repeated Low-Level Red-Light Therapy on Retinal Function and Structure
The purpose of this clinical trial is to evaluate the effect of repeated low-level red-light (RLRL) therapy on the retinal function and structure among myopic teenagers.
- Conditions
- Myopia, Refractive Errors, Eye Diseases, Retina; Change
- Trial name
- NCT05597397
- Testing
- RLRL
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Retina Disease, Glaucoma
Optic Disc Photograph Collection Study
The objective of this study is to collect stereo-optic disc photographs for potential future analysis.
- Conditions
- Retina Disease, Glaucoma, Normal
- Trial name
- NCT05532410
- Testing
- Fundus Camera
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Normal, Retina Disease
P200TE and Predicate Agreement and Precision Study
This study is a prospective comparative, randomized, single center study to assess agreement and precision of the P200TE in comparison to the predicate device in normal subjects, subjects with glaucoma, and subjects with retinal…
- Conditions
- Normal, Retina Disease, Glaucoma
- Trial name
- NCT05624593
- Testing
- P200TE, Predicate
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Retina Disease, Glaucoma
P200TE Agreement and Precision Study
This study is a prospective comparative, randomized, single center study to assess agreement and precision of the P200TE in comparison to the predicate device in normal subjects, subjects with glaucoma, and subjects with retinal…
- Conditions
- Retina Disease, Glaucoma, Normal
- Trial name
- NCT05536401
- Testing
- P200TE, Predicate Device
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Retina Disorder
A New Technique For Retinal Disease Treatment
With the advent of the era of precision medicine, based on FFA image deep learning to identify the area of fundus lesions, registration of fundus images, according to the severity of fundus diseases to design the optimal laser…
- Trial name
- NCT04718532
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Retinal Vascular, Retinal Disease
Perifoveal Vascular Network Assessed by OCT-Angiography in Type I Diabetes Mellitus
This study is directed to evaluate the role of Optical Coherence Tomography Angiography (OCT-A) in the evaluation of the perifoveal vascular network in type 1 diabetic patients, and to investigate the relationship between…
- Conditions
- Retinal Vascular, Retinal Disease, Retinal Ischemia, Retinal Ischaemia Due to Type 1 Diabetes Mellitus
- Trial name
- NCT03422965
- Testing
- Optical Coherence Tomography Angiography, Blood test, Urine test
- Where
- 2 sites in Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Retina--Diseases, Retinal Detachment
Evaluation of Discomfort Associated With Scleral Depression During Retina Examinations
Scleral depression is an important technique used to examine the peripheral retina but often causes patient discomfort. The goal of this study was to compare levels of discomfort during scleral depression with a Schocket scleral…
- Conditions
- Retina--Diseases, Retinal Detachment, Retinal Degeneration
- Trial name
- DEPRESS (NCT04115917)
- Testing
- Schocket scleral depressor, Cotton tipped applicator
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Macula; Degeneration, Congenital or Hereditary, Retina Disorder
Objective Assessment of Macular Function at Retinal and Cortical Levels
Research questions/hypotheses: About 15% of the population over 40 years of age are affected by diseases of the retina. Accurate measurement of the extent of visual field impairment is of highest importance for disease subtype…
- Trial name
- NCT03517241
- Testing
- functional magnetic resonance imaging (fMRI), Microperimetry (MP), Optical coherence tomography (OCT)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Eye Diseases, Retina; Lesion
Comparison of Non-mydriatic Camera Systems in a Female Health Hospital
1. To compare quality and usability of images taken by two different camera-systems without dilating the pupil. 2. To compare the retinal vessel diameters based on the images of to different camera-systems. 3.
- Conditions
- Eye Diseases, Retina; Lesion, Optic Disc Structural Anomaly
- Trial name
- NCT02089009
- Testing
- Retinal imaging, Vessel measurements, Change in vessel diameters
- Where
- 2 sites in Germany
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Dr. Martin Leitritz
Cornea, Retina
Spectral-domain Optical Coherence Tomography of the Eye
An increasing number of clinical studies on SD-OCT of ocular pathologies and potential new clinical applications has recently been published in the peer-reviewed literature.
- Conditions
- Cornea, Retina, Refractive Surgery, Macular Edema
- Trial name
- NCT02614625
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Augenabteilung Allgemeines Krankenhaus Linz