Clinical trials: Retrospective
Progressive Multifocal Leukoencephalopathy
Retrospective Study of the Survival of Patients Suffering From Hiv-related Progressive Multifocal Leukoencephalopathy
Retrospective medical chart review of HIV-infected patients diagnosed with progressive multifocal leukoencephalopathy
- Trial name
- LEMPMAR (NCT02895581)
- Volunteers
- 34 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Hemoglobinopathies
Prevalence of Hemoglobinopathies Associated With Significant Hb Variants in the Chattogram Region of Bangladesh
Hemoglobinopathies represent a collection of genetic conditions that influence the structure or synthesis of haemoglobin, the protein found in red blood cells that facilitates oxygen transport from the lungs throughout the body.
- Trial name
- Hb variants (NCT07207551)
- Where
- Bangladesh
- Volunteers
- 760 people
- Sponsor
- Bangladesh Bioscience Research Group
Dyslipidemia, Hypercholesterolemia
Real World Adherence of PCSK9 Targeted Therapy
Retrospective observational cohort study to compare medication adherence at 12 months between patients in Japan with dyslipidemia and/or hypercholesterolemia (familial and non-familial hypercholesterolemia) who newly initiate…
- Trial name
- NCT07468500
- Volunteers
- 3,600 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer
ROLL Versus Magnetic Seed for Preoperative Localization of Non-palpable Breast Lesion: Comparison Between Techniques.
Nowadays, Breast Conservative Surgery (BCS) is the standard of care for patients affected by early breast lesions. Screening programmes led to an increase of impalpable breast lesion detection rates.
- Trial name
- SEED01 (NCT05942092)
- Testing
- Breast conserving surgery
- Where
- Italy
- Volunteers
- 1,400 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Wet Macular Degeneration
Real Life of Aflibercept in France in Patients Refractory to Ranibizumab: Observational Study in Wet AMD
The aim of the TITAN study is to describe the clinical practices of a cohort of patients with wAMD refractory to ranibizumab (persistence of intra-retinal and/or subretinal fluid) who switch to aflibercept after less than 12…
- Trial name
- TITAN (NCT02321241)
- Testing
- Aflibercept (EYLEA, BAY-86-5321)
- Where
- France
- Volunteers
- 236 people
- Sponsor
- Bayer
High-Frequency Jet Ventilation, Bronchoscopy
Complications of High Frequency Jet Ventilation
High frequency jet ventilation (HFJV) has been introduced in 1967 as technique allowing ventilation with simultaneous access to the airway for bronchoscopy.
- Trial name
- NCT06285994
- Testing
- High frequency jet ventilation
- Where
- Belgium
- Volunteers
- 1,385 people
- Sponsor
- Erasme University Hospital
Respiratory Distress Syndrome, Adult, Covid19
High-Dose Vitamin C Treatment in Critically Ill COVID-19 Patients
Acute respiratory failure due to COVİD-19 pneumonia has poor prognosis and high mortality . Both the lack of an effective antiviral treatment and the low level evidence of the recommendations presented in the guidelines on other…
- Trial name
- NCT04710329
- Testing
- Ascorbic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Surgery, Proteinuria
Postoperative New-onset Proteinuria and Adverse Outcomes.
We aimed to assess the association between postoperative new-onset proteinuria, all-cause mortality, and decline in kidney function in Chinese people who underwent surgery.
- Conditions
- Surgery, Proteinuria, Mortality
- Trial name
- NCT06339229
- Testing
- proteinuria
- Volunteers
- 2,983,899 people
- Sponsor
- Yaozhong Kong
Chronic Kidney Disease
REVEAL-CKD: Prevalence and Consequences of Undiagnosed Chronic Kidney Disease
This is a retrospective, multinational, non-interventional, observational study. A series of cohort studies will be conducted to assess the prevalence of undiagnosed stage 3 CKD in each region.
- Trial name
- REVEAL-CKD (NCT04847531)
- Where
- 13 sites in United States, Australia and 9 more
- Volunteers
- 1,006,361 people
- Sponsor
- AstraZeneca
Lumbar Disc Herniation
Intradiscal Ozone/Oxygen Injection for Treatment of Contained Lumbar Disc Herniation
This study is retrospectively designed and aims to evaluate and summarize safety and performance data in eligible participants who have undergone Intradiscal ozone-oxygen injection for treatment of lumbar disc herniation with the…
- Trial name
- NCT07910422
- Testing
- Intradiscal ozone-oxygene injection
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Beam Research, Inc.
Severe Asthma
Study in Portuguese Hospitals to Describe Patient Characteristics, Treatment Patterns and Outcomes
Benralizumab is indicated as an add-on maintenance treatment in adult patients with severe eosinophilic asthma inadequately controlled despite high-dose inhaled corticosteroids plus long-acting β2-agonists.
- Trial name
- Betreat (NCT07159295)
- Where
- 16 sites in Portugal
- Volunteers
- 74 people
- Sponsor
- AstraZeneca
Post Concussive Syndrome, Chronic, Post Concussion Symptoms
Accelerated Transcranial Magnetic Stimulation Intervention for Post-Concussion Syndrome
This study looks at the effects of accelerated intermittent theta burst stimulation (aiTBS) on patients with chronic and acute post-concussion syndrome.
- Conditions
- Post Concussive Syndrome, Chronic, Post Concussion Symptoms, Post Concussive Syndrome, Post Concussion Syndrome
- Trial name
- NCT07211919
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Cognitive FX
Heart Failure
Heart Failure Treatment Pattern Analysis of HF Patients in HF Centers and Non-HF Centers in China
This is a retrospective, researcher-initiated, database-based study that will retrospectively observe the treatment and medication patterns of about 22,500 patients with heart failure from 25 heart failure centers and 25…
- Trial name
- NCT06099028
- Testing
- no intervention
- Where
- China
- Volunteers
- 22,500 people
- Sponsor
- Peking University First Hospital
Chronic Obstructive Pulmonary Disease COPD
Long-term Real-world Study of Dupilumab in COPD : Patient Characteristics, Safety and Patient-reported Outcomes
The OBS19236 is a retrospective and prospective, non-interventional observational study in COPD patients treated with dupilumab as part of routine clinical care.
- Trial name
- AURORA (NCT07380711)
- Where
- 28 sites in France
- Volunteers
- 500 people
- Sponsor
- Sanofi
Pemphigus Disease, Rituximab (RTx)
Efficacy and Safety of Different Doses of Rituximab Therapy in Pemphigus Patients
Investigating the clinical efficacy of different doses of rituximab in patients with pemphigus
- Trial name
- NCT07457944
- Where
- China
- Volunteers
- 275 people
- Sponsor
- Ruijin Hospital
COVID-19, COVID-19 Pandemic
Accelerating COVID-19 Clinical Recovery in the Outpatient Setting: Retrospective Analysis
The purpose of this retrospective study is to evaluate the effectiveness of CPM nasal spray as part of the treatment of COVID-19 and its impact on clinical symptoms. Two cohort groups will be compared (CPM vs. standard care).
- Conditions
- COVID-19, COVID-19 Pandemic, COVID-19 Respiratory Infection, SARS CoV 2 Infection
- Trial name
- ACCROS-R (NCT05520944)
- Testing
- ClorNovir® (Chlorpheniramine) 0.4% Nasal Spray
- Where
- Dominican Republic
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dr. Ferrer BioPharma
Interstitial Lung Disease
Interstitial Lung Disease Registry Study: Prospective and Retrospective Observational Study in Austria
The goal of this registry is to systematically record epidemiological and clinical data throughout the whole interstitial lung disease course - starting with the diagnosis, therapy, follow up of lung function, symptom control…
- Trial name
- NCT06522334
- Where
- 5 sites in Austria
- Volunteers
- 400 people
- Sponsor
- Ludwig Boltzmann Institute for Lung Health
Guideline Implementation
Retrospective Evaluation of ASIPP Guidelines Implementation
To demonstrate clinically significant improvements in the patients treated following ASIPP guidelines compared to the patients who were treated prior to the establishment of ASIPP guidelines.
- Trial name
- NCT00372164
- Testing
- American Society of Interventional Pain Physician Guidelines
- Where
- United States
- Sponsor
- Pain Management Center of Paducah
Breast Cancer
Exploring the Role of Serum Methylmalonic Acid (MMA) in Breast Cancer
This project aims to investigate the role of MMA in breast cancer. To this end, we will measure MMA on serum samples collected at the time of breast cancer diagnosis, to investigate the role of MMA in predicting long-term…
- Trial name
- NCT05352737
- Testing
- methylmalonic acid testing
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Talus Fracture
Treatment of Talus Fractures: a Retrospective Study
The main purpose of this retrospective case series study was to evaluate long-term radiographic and clinical outcomes of a consecutive series of patients with diagnosis of isolated, displaced, closed talar neck or body fractures…
- Trial name
- TTF2017 (NCT03639272)
- Testing
- open reduction and internal fixation (ORIF).
- Volunteers
- 40 people
- Sponsor
- University of Padova
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