Clinical trials: Retrospective
Exudative Age-Related Macular Degeneration
Study of Switching to Aflibercept 8 mg in Patients With Refractory or Dependent Exudative Age-related Macular Degeneration
Age-related macular degeneration is a leading cause of visual impairment in older adults. In its exudative form, repeated intravitreal injections of anti-VEGF agents are required to control disease activity.
- Trial name
- AFLIWEST (NCT07423429)
- Testing
- aflibercept 8 mg
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Analgesics Grade 2's Addiction
Prevalence, Management and Follow-up of Patients With Addiction to Opioid Analgesics
The demand for addiction care for patients with addiction to analgesics increases with the number of prescription of analgesics grade 2; this is a public health problem There is no support for repositories to date in the context…
- Trial name
- NCT03297853
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Montpellier
Rhabdomyolysis, Myoglobinuria
Incidence of Rhabdomyolysis Among Patients Admitted With Jimsonweed Ingestions
Retrospective chart review to determine the presence of rhabdomyolysis among patients admitted to CHMCA from 1997-2007 with Jimsonweed ingestions and to define possible risk factors predisposing patients to the developement of…
- Conditions
- Rhabdomyolysis, Myoglobinuria, Hemoglobinuria
- Trial name
- NCT00592657
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Akron Children's Hospital
Cerebrospinal Fluid Leak
Suturable DuraGen™ PMCF Study
The primary goal of this study is to retrospectively collect data on the safety and efficacy of Suturable DuraGen™.
- Trial name
- NCT04923867
- Testing
- Suturable DuraGen™
- Where
- 3 sites in United States
- Volunteers
- 106 people
- Sponsor
- Integra LifeSciences Corporation
Alpine Accident, Frostbite
10-years Nationwide Alpine Accidents in Austria
This observational study intends to analyze the characteristic of specific accidents happened in Austrian's mountainous regions.
- Conditions
- Alpine Accident, Frostbite, Cardiopulmonary Arrest With Successful Resuscitation, Lightning Injuries
- Trial name
- NCT03405467
- Testing
- general and specific data
- Where
- Austria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Hip Fractures
Haemodynamic Effects of Low-dose Spinal Anaesthesia for Hip Fracture Surgery.
Approximately 65, 000 hip fractures occur in the United Kingdom (UK) each year, and more than 99% are repaired by surgery. Roughly half of patients receive spinal anaesthesia, where a small amount (usually less than half a…
- Trial name
- NCT05799300
- Testing
- Intrathecal anaesthesia
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Royal Sussex County Hospital
Malocclusion, Angle Class II
Therapeutic Effects of Class II Elastics on Aligners in Different Vertical Skeletal Patterns
The objective is to compare the dento-alveolar therapeutic effects of wearing class II inter-arch traction elastics on aligners versus multi-brackets in an adult population.
- Trial name
- NCT05853211
- Testing
- Aligner and inter-arch elastics
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Breast Cancer Survivors, Range of Motion
Effects of MMV Exercise With and Without Verbal Guidance on Shoulder Movement, Fatigue, and Stress in Breast Cancer Survivors
The goal of this clinical trial is to learn whether a multimodal exercise rehabilitation program with verbal cueing is more effective than the same exercise program without verbal cueing in improving shoulder movement, reducing…
- Conditions
- Breast Cancer Survivors, Range of Motion, Cortisol, Shoulder Dysfunction
- Trial name
- NCT07367334
- Testing
- Multimodal Exercise Rehabilitation With Verbal Cueing, Multimodel Exercises Rehabilitation without Verbal cues
- Where
- India
- Volunteers
- 34 people
- Sponsor
- Saveetha University
Cytomegalovirus (CMV)
A Study on Cytomegalovirus (CMV) Infection Outcomes Among Hematopoietic Stem Cell Transplant (HSCT) Participants in Europe and Canada
The main aim of the study is to assess the clinical outcomes of current CMV management across different regions of the world (Europe [EU] and Canada [CAN]). Data will be collected retrospectively from medical charts.
- Trial name
- NCT05571137
- Where
- 11 sites in Austria, Belgium and 5 more
- Volunteers
- 118 people
- Sponsor
- Takeda
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University
Pneumonia
5 Years Mortality-rate in Patients Treated for Severe Pneumonia in an ICU - a Retrospective Study
Severe pneumonia has a high in-hospital mortality. There are few studies which investigate the long-term mortality in patients that are discharged alive from the hospital.
- Trial name
- pneumonia (NCT02212093)
- Where
- Norway
- Volunteers
- 236 people
- Sponsor
- University Hospital, Akershus
Wrinkles and Rhytides
Treatment of Aging Signs of the Skin With Bipolar Radiofrequency
This is a retrospective data collection from patients treated with the bipolar radiofrequency applicator (Coaxipolar) of the Accent devices.
- Trial name
- NCT07739212
- Where
- Kosovo
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Alma Mater Europaea College of Medical Sciences "Rezonanca"
Sickle Cell Disease
Is the Preoperative Preparation of Sickle Cell Patients Optimal: Assessment of Practices and Post-operative Complications
Children with sickle cell disease systematically receive a transfusion 2 to 5 days before scheduled surgery (with the exception of minor surgeries) in order to avoid post-operative complications of which the vaso-occlusive crisis…
- Trial name
- NCT04264871
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Queen Fabiola Children's University Hospital
Colon Adenocarcinoma
COLON ERDERLY LOW DOSE
In this retrospective observational study, the case series of patients undergoing first-line treatment for metastatic colorectal adenocarcinoma with doublet fixed-dose and reduced-dose chemotherapy in combination with full-dose…
- Trial name
- CELOW (NCT06840977)
- Where
- 2 sites in Italy
- Volunteers
- 51 people
- Sponsor
- Matteo Clavarezza
Diabetes Mellitus, Type 2
Real World Effectiveness of Oral Semaglutide in Thailand Participants With Type 2 Diabetes
This study aims to describe the effectiveness of oral semaglutide on glycemic control and body weight control and describe characteristics of type 2 diabetes (T2D) adult patients who are being treated with oral semaglutide in…
- Trial name
- REALISED (NCT06507475)
- Testing
- Semaglutide
- Where
- Thailand
- Volunteers
- 209 people
- Sponsor
- Novo Nordisk A/S
Non Small Cell Lung Cancer
A Retrospective Study: Evaluation of the Efficacy of Immunotherapy With Rare Mutations in Non-small Cell Lung Cancer
In advanced non-small cell lung cancer, there will be some rare mutations, such as ALK, KRAS, etc. The efficacy of these immunotherapies on these different rare mutations has not been reported.
- Trial name
- NCT04777175
- Testing
- immunity therapy
- Where
- 2 sites in China
- Volunteers
- 186 people
- Sponsor
- Yongchang Zhang
Chronic Granulomatous Disease
IL-1 Receptor Inhibitor for Granulomatous Complications in Patients With Chronic Granulomatous Disease
"Kineret" (INN: Anakinra) neutralizes the biological activity of interleukin-1α (IL-1α) and interleukin-1β (IL-1β) by the concurrent inhibition of binding to interleukin-1 receptor I (IL-1RI).
- Trial name
- NCT04136028
- Testing
- Kineret
- Where
- Russia
- Volunteers
- 13 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Pleomorphic Lobular Breast Carcinoma in Situ, Breast Florid Lobular Carcinoma in Situ
Pure Florid and Pleomorphic Lobular Carcinoma in Situ of the Breast: Towards an Increasingly Uniform Management
The goal of this retrospective multicenter observational study is to understand and evaluate the diagnostic and therapeutic management of pure forms of Florid Lobular Carcinoma In Situ (FLCIS) and Pleomorphic Lobular Carcinoma In…
- Trial name
- NCT06133465
- Testing
- Surgical wide local excision, Cavity shaving, Excision margin surgical clearance
- Where
- Italy
- Volunteers
- 1,063 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Type 1 Diabetes Mellitus
CloudConnect: Predictive And Retrospective Clinical Decision Support For Chronic Disease Management
This study is to assess an approach of self-management called CloudConnect, evaluating the impact of CloudConnect Reports on patient engagement, adolescent/parent discussion, and clinical outcomes in adolescent Type 1 Diabetes…
- Trial name
- NCT03676465
- Testing
- CloudConnect Report, Will not receive a CloudConnect Report
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Virginia
Tumor Microenvironment, Antibody
A Pan-Cancer Retrospective Study on the Relationship Between Tumor Microenvironment Composition and Efficacy of Antibody-Based Antitumor Therapy
This study is a single-center, retrospective, observational cohort investigation conducted at Tianjin Cancer Hospital that aims to evaluate the relationship between tumor microenvironment (TME) composition and the efficacy of…
- Trial name
- NCT07584044
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
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