Clinical trials: Reverse Shoulder Replacement
Shoulder Arthritis, Blood Loss, Surgical
Effect of TXA on Blood Loss in Reverse Total Shoulder Arthroplasty
Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent that has been well studied and routinely used for hip and knee arthroplasty.
- Conditions
- Shoulder Arthritis, Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
- Trial name
- NCT06638749
- Testing
- Tranexamic Acid, Normal Saline
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Reverse Shoulder Replacement
EMG Biofeedback and NMES of Deltoid in Patients With rTSA
The effect of NMES and surface electromyography (sEMG) biofeedback on the deltoid and associated scapular muscles in scapular kinematics and muscle activation in individual post rTSA
- Trial name
- NCT06873022
- Testing
- neuromuscular electrical stimulation, biofeedback
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- National Taiwan University Hospital
Closed Fracture Proximal Humerus, Four Part
Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures
Will patients who suffer complex humerus fractures have better functional outcomes and less implant failure with shoulder replacement (reverse total shoulder arthroplasty, RTSA) compared to shoulder repair (open reduction and…
- Trial name
- NCT02597972
- Testing
- Fracture repair, Fracture repair with joint replacement
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Diaphragmatic Paralysis, Anterior Suprascapular Nerve Block
Combined Anterior Suprascapular Nerve Block and Superficial Cervical Plexus Block In Shoulder Arthroplasty Surgery
The suprascapular nerve, originating from the C5 trunk, provides innervation to the acromioclavicular and glenohumeral joints. The supraclavicular nerve, a branch of the cervical plexus, contributes to the sensory innervation of…
- Conditions
- Diaphragmatic Paralysis, Anterior Suprascapular Nerve Block, Superficial Cervical Plexus Block, Phrenic Nerve Paralysis
- Trial name
- NCT06146179
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Istanbul Medeniyet University
Rotator Cuff Tear Arthropathy
Impact of Humeral Component Version on Outcomes Following RTSA
The proposed study is a prospective, single-blinded, randomized trial to investigate the impact of humeral component version on shoulder range of motion and patient reported functional outcomes following reverse total shoulder…
- Trial name
- NCT03111147
- Testing
- 0 degrees humeral component version, 30 degrees humeral component retroversion
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Corewell Health East
Rotator Cuff Arthropathy
Focus on the Humeral Component Following Reverse Shoulder Arthroplasty
Reverse total shoulder arthroplasty has been widely used in the treatment of rotator cuff arthropathy. Follow-up has historically focused on the glenoid component because of problems with fixation and scapular notching leading to…
- Trial name
- RSA (NCT04809077)
- Testing
- Reverse total shoulder replacement
- Where
- Belgium
- Volunteers
- 123 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Arthroplasty, Replacement
SMR Stemless Reverse vs SMR Reverse Shoulder System
The SMR Stemless Reverse is intended for total, primary shoulder joint replacement by reducing pain and restoring shoulder articular mobility function.
- Trial name
- NCT04697004
- Testing
- Investigational Arm: SMR Stemless Reverse, Control Arm: SMR Reverse Shoulder System
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- Limacorporate S.p.a
Osteoarthritis, Rotator Cuff Tear Arthropathy
Prediction of Development of Scapular Notching Following Reverse Total Shoulder Arthroplasty
The hypothesis is that computer simulated bony impingement of the bone surrounding the spherical glenoid implant (the glenosphere) along the scapular neck on three-dimensional (3-D) computed tomography (CT) imaging analysis is…
- Conditions
- Osteoarthritis, Rotator Cuff Tear Arthropathy, Reverse Total Shoulder Arthroplasty, Scapular Notching
- Trial name
- NCT02052466
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Eric Ricchetti
Shoulder Injuries, Shoulder Pain
Reverse Shoulder Arthroplasty vs Rotator Cuff Repair for 60+
To compare the one year outcomes between 60 year old patients with a three tendon tear treated as part of their standard of care with either a reverse total shoulder arthroplasty or rotator cuff repair surgery.
- Trial name
- RTSA-RCR (NCT06848023)
- Testing
- Reverse Total Shoulder Arthroplasty, Rotator Cuff Repair
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Campbell Clinic
Shoulder Arthritis, Rotator Cuff Tear Arthropathy
Home Exercise vs PT for Reverse Total Shoulder Arthroplasty
The primary objective of this study is to compare outcomes between formal clinic based physical therapy (PT) rehabilitation and surgeon directed home therapy (HT) after reverse total shoulder arthroplasty (RSA) as measured by…
- Trial name
- NCT03719859
- Testing
- Physical Therapy, Home Therapy
- Where
- 7 sites in United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Arthritis
Evaluation of Implant Fixation in Reverse Total Shoulder Arthroplasty
Reverse total shoulder replacement surgery (RTSA) is performed for individuals with advanced arthritis of the shoulder who also have tears in their rotator cuff muscles.
- Trial name
- NCT02305966
- Testing
- surgery, 0.8 mm diameter Tantalum marker beads
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Reverse Shoulder Replacement
Tornier Blueprint Planning Software in Patients Receiving Reverse Shoulder Arthroplasty
Compare sizing determined in pre-operative planning of reverse shoulder arthroplasty to operative implant size selected.
- Trial name
- NCT04474665
- Testing
- Reverse shoulder arthroplasty utilizing Blueprint Software
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Spine Institute of Louisiana Foundation
Opioid Use, Shoulder Osteoarthritis
Opioid-Free Shoulder Arthroplasty
Purpose of Study: To identify and provide a safe, opioid-free treatment pathway for shoulder arthroplasty with a focus on perioperative pain control and postoperative symptoms from treatment
- Conditions
- Opioid Use, Shoulder Osteoarthritis, Avascular Necrosis, Rotator Cuff Tear
- Trial name
- NCT03540030
- Testing
- Gabapentin, Celecoxib, toradol
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Humeral Fracture, Proximal
Reverse Total Shoulder Arthroplasty Versus Hemiarthroplasty for Displaced 3- and 4-part Proximal Humeral Fractures
Proximal humeral fractures are common injuries with the highest incidence being amongst the elderly. Most proximal humeral fractures are nondisplaced or minimally displaced.
- Trial name
- NCT03383991
- Testing
- Reverse Total Shoulder Arthroplasty, Hemiarthroplasty
- Sponsor
- Karolinska Institutet
Glenohumeral Osteoarthritis
Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis
The primary goal of the investigators prospective randomized study is to determine whether reverse total shoulder arthroplasty (RTSA) have at least as good results as anatomic TSA (non-inferiority), in patients with glenohumeral…
- Trial name
- NCT06513559
- Testing
- Anatomic total shoulder replacement, Reverse total shoulder replacement
- Where
- United States
- Sponsor
- University of Utah
Primary Reverse Total Shoulder Arthroplasty
Does Undergoing a Prehabilitation Protocol Aimed at Optimizing Scapulothoracic Mobility and Strengthening Improve Internal Rotation After Reverse Shoulder Arthroplasty?
Difficulty with internal rotation (IR) after reverse shoulder arthroplasty (RSA) is common. Current rehabilitation protocols may not optimize IR.
- Trial name
- NCT07145957
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Florida
Blood Loss, Anatomic Total Shoulder Arthroplasty
Investigation of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty
To compare intravenous Tranexamic Acid (TXA) versus normal saline placebo to determine whether or not TXA administration reduces blood loss, decrease in hemoglobin, and rate of transfusions following anatomic and reverse total…
- Conditions
- Blood Loss, Anatomic Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Transfusion
- Trial name
- NCT02569658
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Arthroplasty, Replacement, Shoulder, Shoulder Osteoarthritis
Does BIO-RSA Provides Superior Clinical Outcome Compared to Conventional RSA?
The goal of this clinical trial is to compare two different types of reverse shoulder replacements. Researchers will compare a conventional reverse shoulder replacement with a lateralized reverse shoulder replacement to see if…
- Trial name
- CARS-1 (NCT06025331)
- Testing
- BIO-RSA, RSA
- Where
- 2 sites in Norway
- Volunteers
- 130 people
- Sponsor
- Lovisenberg Diakonale Hospital
Shoulder Disease, Rotator Cuff Tear Arthropathy
Sling vs No Sling After Reverse Total Shoulder Arthroplasty
This study involves patients who will be undergoing a reverse total shoulder replacement at Duke University. 100 eligible will be randomly assigned into one of two groups, a sling or no sling group.
- Conditions
- Shoulder Disease, Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
- Trial name
- NCT06092996
- Testing
- Time of Sling Use
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Reverse Shoulder Arthroplasty
Comparison of Lateralized RTSA With and Without Subscapularis Repair
The purpose of this double-blind randomized controlled trial is to compare patient-reported, clinical, and functional outcomes in patients undergoing RTSA with and without subscapularis repair after placement of a modern…
- Trial name
- NCT04728282
- Testing
- RTSA with subscapularis repair, RTSA without subscapularis repair
- Where
- 6 sites in Canada
- Volunteers
- 284 people
- Sponsor
- Panam Clinic