Clinical trials: RhA - Rheumatoid Arthritis
Arthritis of Temporomandibular Joint, Temporomandibular Arthritis
Treatment of Temporomandibular Joint Osteoarthritis by Viscosupplement. Satisfaction Predictive Factors
The arthritis of temporomandibular joint is the most frequent degenerative disease of the jaw joint. Several clinical studies recommend the recourse to the viscosupplement because of its efficiency in the long term.
- Trial name
- ARTEMIS (NCT03627429)
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Labrha
Rheumatoid Arthritis
A Study to Assess the Effect of Tocilizumab + DMARD Therapy on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis
This 2 arm study will compare the safety and efficacy, with regard to reduction of signs and symptoms, of tocilizumab versus placebo in combination with traditional Disease-Modifying Anti-Rheumatic Drug (DMARD) therapy in…
- Trial name
- NCT00106574
- Testing
- tocilizumab [RoActemra/Actemra]
- Where
- 146 sites in United States, Argentina and 17 more
- Volunteers
- 1,220 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Venlafaxine as Adjunct Therapy in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent inflammation of the joints, leading to pain, swelling, disability, and reduced quality of life.
- Trial name
- NCT07497282
- Testing
- venlafaxine extended-release (XR), Standard conventional Rheumatoid Arthritis Therapy
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Rheumatoid Arthritis
A Study of Tocilizumab as Monotherapy or in Combination With DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis
This open-label single-arm study will evaluate the safety, tolerability and efficacy of tocilizumab [RoActemra/Actemra] in patients with moderate to severe rheumatoid arthritis who experience an inadequate clinical response to a…
- Trial name
- NCT01089023
- Testing
- tocilizumab [RoActemra/Actemra]
- Where
- 9 sites in Bahrain, Iran and 3 more
- Volunteers
- 95 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Predicting the Response of Patients With Rheumatoid Arthritis to Treatment With Genetically Engineered Biological Drugs and Janus (JAK) Kinase Inhibitors
Rheumatoid arthritis (RA) is a chronic disease affecting about 1% of the worldwide population. RA is characterized by inflammation of the synovial membrane joints, which can lead to the destruction of the osteochondral structures…
- Trial name
- NCT06177405
- Testing
- genetically engineered biological drugs, Janus-kinase inhibitors, tumor necrosis factor inhibitors
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Institute of Biomedical Chemistry, Russia
Rheumatoid Arthritis
Coping Skills Training for Early Rheumatoid Arthritis
Rheumatoid arthritis (RA) is the most common inflammatory arthritis and a major health problem. Medical treatments are now being used much earlier in the course of RA, but these treatments do not address the challenges of coping…
- Trial name
- NCT00056394
- Testing
- Comprehensive Coping Skills Training, Arthritis Education Sessions, Standard Care
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- Duke University
Rheumatoid Arthritis
GP2013 in the Treatment of RA Patients Refractory to or Intolerant of Standard Therapy
The purpose of this study is to determine the PK/PD, efficacy and safety of GP2013 in patients with severe rheumatoid arthritis.
- Trial name
- NCT01274182
- Testing
- GP2013, MabThera, Rituxan
- Where
- 57 sites in United States, Argentina and 12 more
- Volunteers
- 312 people
- Sponsor
- Sandoz
Rheumatoid Arthritis
A Non-Comparative Study to Assess the Safety of MabThera (Rituximab) in Patients With Rheumatoid Arthritis.
This single arm study will assess the safety of MabThera plus methotrexate in patients with rheumatoid arthritis who have had a lack of response to 1-5 DMARDs or biological agents.
- Trial name
- NCT00502996
- Testing
- Methotrexate, rituximab [MabThera/Rituxan]
- Where
- 49 sites in Argentina, Brazil and 8 more
- Volunteers
- 246 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis, Rheumatoid Arthritis (RA)
Effect of Roflumilast as Add-On Therapy in Rheumatoid Arthritis
Rheumatoid arthritis is a chronic inflammatory disease that causes joint pain, swelling, and reduced physical function. Although standard disease-modifying antirheumatic drugs are effective for many patients, some individuals…
- Trial name
- NCT07632846
- Testing
- Roflumilast 500 Mcg Oral Tablet
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Horus University
Rheumatoid Arthritis
Doppler Evaluation in RA Patients After Adalimumab.
The purpose is to study the relationship between RA disease activity based on Doppler quantification and the subsequent clinical response (EULAR response) to treatment with Adalimumab during 12 months.
- Trial name
- Muscara (NCT01609205)
- Testing
- Adalimumab
- Where
- 2 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Hamed Rezaei
Psoriasis, Rheumatoid Arthritis
BE Study in Patients - Methotrexate Tablets
To characterize the pharmacokinetic profile of the Test product - Methotrexate Tablets USP, 2.5 mg of Amneal Pharmaceuticals, compared to that of the corresponding Reference product - Methotrexate Tablets USP 2.5 mg manufactured…
- Trial name
- NCT02940561
- Testing
- Methotrexate - Amneal, Methotrexate - DAVA
- Where
- 3 sites in India
- Volunteers
- 48 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Autoimmune Diseases
Characterization of the Phenotypic Markers of B Cell Lymphocytes in Rheumatoid Arthritis
Rheumatoid Arthritis (RA): RA is a chronic inflammatory autoimmune disease that primarily affects the small joints, eventually leading to bone erosion and an inability to move (1).
- Trial name
- NCT03793270
- Testing
- for patients and healthy donors
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rheumatoid Arthritis (RA)
Efficacy of Structured Progressive Training Exercise on Muscle Strength of Patients With Rheumatoid Arthritis
This study aims to find out if a specific exercise program helps patients with Rheumatoid Arthritis (RA). RA is a chronic autoimmune disease that causes pain, weakness, and reduced function in the joints and muscles.
- Trial name
- RA (NCT07487779)
- Testing
- Progressive Resistance Training
- Volunteers
- 118 people
- Sponsor
- Kufa University
Rheumatoid Arthritis Disease Flare
Prognostic Factors and Predictors of Disease Flare in Patients With Rheumatoid Arthritis
The goal of this observational study is to help find better ways to predict when a flare of your disease (rheumatoid arthritis) might happen.
- Trial name
- NCT07381296
- Testing
- Clinical and Laboratory Monitoring for RA Disease Flare
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Rheumatoid Arthritis
Pictorial Representation of Illness and Self Measure
PRISM (Pictorial Representation of Illness and Self Measure) has been developed since the mid-1990s; the task was first developed as a simple measure of how a person was coping with his or her experience of illness.
- Trial name
- PRISM (NCT01707186)
- Where
- United Kingdom
- Volunteers
- 220 people
- Sponsor
- University of Oxford
Rheumatic Disease, Rheumatoid Arthritis
The Usefulness of Interferon-γ Release Assays and Tuberculin Skin Test for Detection of Latent Tuberculosis Infection
The purposes of this study 1. to compare the positivity of tuberculin skin test(TST) and QuantiFERON-TB Gold (QFT-G), and determine the level of agreement between two tests in patients with rheumatic diseases 2.
- Conditions
- Rheumatic Disease, Rheumatoid Arthritis, Ankylosing Spondylitis, Tuberculosis
- Trial name
- NCT01685905
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Hanyang University
Rheumatoid Arthritis
Long-term Experience With Abatacept SC in Routine Clinical Practice
The purpose of this study is to estimate the retention rate of Abatacept SC over 24 months in routine clinical practice, in rheumatoid arthritis patients, in each country involved in the study.
- Trial name
- ASCORE (NCT02090556)
- Where
- 12 sites in Australia, Austria and 9 more
- Volunteers
- 2,954 people
- Sponsor
- Bristol-Myers Squibb
Systemic Lupus Erythematosus, Rheumatoid Arthritis
Safety and Tolerability Study Of PF-06835375 In Subjects With Seropositive Systemic Lupus Erythematosus Or Rheumatoid Arthritis
This is a Phase 1 single and multiple dose escalation study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06835375 in subjects with seropositive SLE or RA.
- Trial name
- NCT03334851
- Testing
- PF-06835375
- Where
- 17 sites in United States
- Volunteers
- 74 people
- Sponsor
- Pfizer
Rheumatoid Arthritis
Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Biological Drug Concentration and Clinical Response in Rheumatoid Arthritis Patients Treated With Subcutaneous Injectable Methotrexate and a First Biological Drug
The combination of methotrexate (MTX) with a biological disease-modifying antirheumatic drugs (bDMARD) is the next step in treatment with MTX monotherapy in rheumatoid arthritis (RA).
- Trial name
- POLYbio (NCT04470453)
- Testing
- Blood sample, CRQ
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Rheumatoid Arthritis
A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Therapies.
This single arm study will evaluate the efficacy and safety of MabThera in combination with methotrexate in patients with rheumatoid arthritis who have had an inadequate response to one or more anti-TNF therapies.
- Trial name
- NCT00462345
- Testing
- rituximab, Methotrexate, Corticosteroid or NSAID
- Where
- 4 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Hoffmann-La Roche
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.