Clinical trials: RhA - Rheumatoid Arthritis
Rheumatoid Arthritis
Lingzhi and Sen Miao San for the Treatment of Rheumatoid Arthritis
To study the efficacy of TCM as an effective supplement in addition to the traditional treatment in RA.
- Trial name
- NCT00432484
- Testing
- Lingzhi and Sen Miao San
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Rheumatoid Arthritis
A Study for Japanese Participants With Rheumatoid Arthritis (RA)
This study will evaluate the safety and tolerability of multiple doses of LY2127399 (tabalumab) in Japanese participants with RA. The study consists of a 20-week treatment period.
- Trial name
- NCT01253226
- Testing
- LY2127399 (Tabalumab)
- Where
- 10 sites in Japan
- Volunteers
- 32 people
- Sponsor
- Eli Lilly and Company
Rheumatoid Arthritis
Exercise-induced Improvements of Inflammatory Status in Patients With Rheumatoid Arthritis
The primary aim of the study is to investigate if 10 weeks of high intensity interval training improve inflammatory status in patients with rheumatoid arthritis.
- Trial name
- NCT01478334
- Testing
- high intensity interval training, Control
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Arthritis, Rheumatoid
Treatments Against RA and Effect on FDG-PET/CT
In a randomized controlled clinical trial, investigators will compare the effects on [18F]-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) from two treatment regimens in rheumatoid arthritis (RA)…
- Trial name
- TARGET (NCT02374021)
- Testing
- Methotrexate, Sulfasalazine, Hydroxychloroquine
- Where
- 31 sites in United States
- Volunteers
- 159 people
- Sponsor
- Brigham and Women's Hospital
Rheumatoid Arthritis
Duration of Immune Response to Influenza Vaccination in Patients With RA
The main objective is to evaluate the strength and duration of immune response after influenza vaccination in patients with Rheumatoid Arthritis (RA) receiving treatment with biological agents as compared to a group healthy…
- Trial name
- NCT02311855
- Testing
- Influenza vaccine
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Bassett Healthcare
Cardiovascular Risk Assessment, Rheumatoid Arthritis (RA)
Twenty-four Hour Movement Behaviors and Atherosclerotic Risk
This observational study aims to investigate how 24-hour movement behaviors are associated with atherosclerotic risk in adults with rheumatoid arthritis. These behaviors include physical activity, sedentary behavior, and sleep.
- Conditions
- Cardiovascular Risk Assessment, Rheumatoid Arthritis (RA), 24-Hour Movement Guidelines
- Trial name
- PASSARO (NCT07774507)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- São Paulo State University
Pulmonary Hypertension, Connective Tissue Disease
Exercise and Respiratory Therapy in Patients With Rheumatoid Arthritis / Collagenosis and Pulmonary Hypertension
In Patients with rheumatic disease exercise training is a well established element of therapy. In contrast patients with severe pulmonary hypertension are advised to avoid physical exertion and must not perform exercise training.
- Trial name
- NCT00491309
- Testing
- exercise training
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Heidelberg University
Rheumatoid Arthritis (RA)
An Observational Study to Evaluate Impact of CRP-Level on Real World Effectiveness of Upadacitinib as Monotherapy or in Combination With MTX in Adult Participants With Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. RA can reduce the ability to perform everyday tasks.
- Trial name
- UPWARDS (NCT04267536)
- Where
- 52 sites in Germany
- Volunteers
- 534 people
- Sponsor
- AbbVie
Rheumatoid Arthritis
A Study of PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02).
The study will assess the efficacy and safety of PF-06438179 and infliximab in combination with methotrexate in subjects with active rheumatoid arthritis who have had an inadequate response to methotrexate.
- Trial name
- NCT02222493
- Testing
- PF-06438179, Infliximab
- Where
- 184 sites in United States, Australia and 26 more
- Volunteers
- 650 people
- Sponsor
- Pfizer
Arthritis, Rheumatoid, Arthritis, Psoriatic
PANLAR's Latin American Registry of Rheumatic Patients Treated With Jak Inhibitors
This prospective, non-interventional, research registry is designed to study the comparative safety and comparative effectiveness of approved Jak Inhibitors treatment for RA-PsA-SpA in a cohort of patients and theirs controls…
- Conditions
- Arthritis, Rheumatoid, Arthritis, Psoriatic, Spondyloarthritis
- Trial name
- PREJAK (NCT04821206)
- Testing
- DMARDs, biologic DMARDs, JAK Inhibitor
- Where
- 2 sites in Argentina
- Volunteers
- 3,000 people
- Sponsor
- Liga Panamericana de Asociaciones de Reumatologia (PANLAR)
Rheumatoid Arthritis
Tetrandrine in the Treatment of Rheumatoid Arthritis
The purpose of this study is to assess the efficacy and safety of tetrandrine, compared with placebo in 12 week or 24 week in RA patients with inadequate response to methotrexate.
- Trial name
- NCT05245448
- Testing
- Tetrandrine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University People's Hospital
Early Rheumatoid Arthritis
Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis
The purpose of the study is to assess the safety and efficacy of adalimumab in combination with methotrexate in patients with recent onset rheumatoid arthritis (RA), and to assess the long-term safety and maintenance of efficacy…
- Trial name
- PREMIER (NCT00195663)
- Testing
- Adalimumab, Methotrexate
- Where
- 123 sites in United States, Australia and 17 more
- Volunteers
- 799 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Rheumatoid Arthritis
Effect of Laser Puncture on Rheumatoid Arthritis Patients
Studying the effect of laser puncture on rheumatoid arthritis patients
- Trial name
- NCT04684693
- Testing
- Laser, Control
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Arthritis, Rheumatoid
Ramipril in Rheumatoid Arthritis
The present study is designed to evaluate the hypothesis that the Angiotensin-Converting Enzyme (ACE) inhibitor Ramipril improves vascular function and reduces markers of low-grade chronic inflammation and oxidative stress in…
- Trial name
- NCT00273533
- Testing
- Ramipril
- Volunteers
- 13 people
- Sponsor
- University of Zurich
Active Rheumatoid Arthritis
Study Comparing Etanercept Plus Methotrexate to Either Etanercept or Methotrexate Alone in Rheumatoid Arthritis.
To compare the therapeutic and radiographic effects and safety between etanercept, methotrexate, and the etanercept/methotrexate combination in patients with rheumatoid arthritis.
- Trial name
- NCT00393471
- Testing
- Etanercept
- Where
- 88 sites in Australia, Austria and 17 more
- Volunteers
- 615 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Rheumatoid Arthritis, Interstitial Lung Disease
Tofacitinib in the Treatment of Rheumatoid Arthritis-related Interstitial Lung Disease.
Nowadays, no single drug is approved to treat rheumatoid arthritis-related interstitial lung disease (RA-ILD). The medical management of this clinical condition is empirical and controversial.
- Trial name
- RAILDTo (NCT05246293)
- Testing
- Tofacitinib
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Joint Disease
Post Market Clinical Follow-up Study Protocol for PROFEMUR® Xm Femoral Stems
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) and resurfacing components marketed in the European Union (EU).
- Trial name
- NCT02309593
- Testing
- PROFEMUR® Xm Femoral Stems
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- MicroPort Orthopedics Inc.
Rheumatoid Arthritis
CorEvitas Japan Rheumatoid Arthritis (RA) Registry
The primary objective is to prospectively study the comparative effectiveness and comparative safety of approved therapies for RA in a Japanese cohort of patients treated by rheumatologists.
- Trial name
- NCT02737449
- Volunteers
- 2,000 people
- Sponsor
- CorEvitas
Rheumatoid Arthritis
Study Evaluating Gerilimzumab´s Safety/Efficacy for Patients MTX or TNFα Antagonist Failed in Rheumatoid Arthritis
Phase 2 Study Evaluating Gerilimzumab's Safety/Efficacy for Patients with an Inadequate Response to MTX or a TNFα Antagonist in Rheumatoid Arthritis.
- Trial name
- NCT02795299
- Testing
- Gerilimzumab, Methotrexate, Folic Acid
- Sponsor
- Bird Rock Bio, Inc.
Rheumatoid Arthritis
Assessment of 14-3-3 η (Eta) Protein Antibodies in the Serum of Rheumatoid Arthritis Patients and Its Relation to Atherosclerosis.
The aims of this study are: • To assess 14-3-3 η (eta) protein antibodies in the serum of rheumatoid arthritis patients and its relation to disease activity and severity.
- Trial name
- NCT04937140
- Testing
- 14-3-3 η (eta) protein antibodies in the serum of rheumatoid arthritis patients
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sohag University