Clinical trials: RhA - Rheumatoid Arthritis
Rheumatoid Arthritis
A Phase III Study to Evaluate the Efficacy and Safety of ENIA11 in Combination With Methotrexate Versus Methotrexate Alone in Patients With RA
A Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of ENIA11 in Combination with Methotrexate versus Methotrexate Alone in Patients with…
- Trial name
- ENIA11 (NCT01709760)
- Testing
- Methotrexate, ENIA11
- Where
- 8 sites in Taiwan
- Volunteers
- 91 people
- Sponsor
- Mycenax Biotech Inc.
Rheumatoid Arthritis
Exercise Perceptions and Preferences Among Rheumatoid Arthritis Patients
The purpose of the study is to analyse exercise behaviour of rheumatoid arthritis patients.
- Trial name
- NCT01596348
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Lausanne
Rheumatic Diseases, Lupus Erythematosus, Systemic
Pain Phenotyping of Rheumatic Diseases - An Observational Study
Background: Rheumatic diseases can affect the joints, ligaments, tendons, bones, muscles, and skin. They can also cause inflammation, damage body tissues, and change nerve signals in the brain.
- Conditions
- Rheumatic Diseases, Lupus Erythematosus, Systemic, Lupus Vasculitis, Central Nervous System, Arthritis
- Trial name
- NCT07829497
- Testing
- Bedside quantitative sensory testing
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Rheumatoid Arthritis, Osteoarthritis
Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement
The purpose of this study is to monitor the performance of a large metal-on-metal bearing from the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery or a total hip…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872547
- Testing
- DePuy ASR™ Hip System, DePuy ASR™ XL Head / ASR™ Acetabular Cup System
- Where
- 8 sites in Austria, Czechia and 6 more
- Volunteers
- 329 people
- Sponsor
- DePuy International
Rheumatoid Arthritis
Natrunix or Placebo in Combination With Methotrexate in Rheumatoid Arthritis
Phase II, Double-Blind, Placebo-Controlled, Randomized Trial Examining Natrunix in Combination with MTX (+Folate) for the Treatment of Rheumatoid Arthritis
- Trial name
- NCT05363891
- Testing
- Natrunix
- Where
- 26 sites in United States
- Volunteers
- 243 people
- Sponsor
- XBiotech, Inc.
Rheumatoid Arthritis, Periodontitis
Prolactin Hormone in Rheumatoid Arthritis Patients With Periodontitis
In this study we will assess the presence of prolactin hormone in the gingival crevicular fluid , and synovial fluid of patient with rheumatoid arthritis and periodontitis
- Trial name
- NCT04279691
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Rheumatoid Arthritis
A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)
To investigate the efficacy and safety of AK106-001616 in patients with rheumatoid arthritis.
- Trial name
- NCT01285752
- Testing
- AK106-001616, Active comparator
- Where
- 26 sites in Czechia, Germany and 5 more
- Volunteers
- 240 people
- Sponsor
- Asahi Kasei Therapeutics Corporation
Inflammatory and Non-inflammatory Bone and Joint Diseases
"Translating Articular Biomarkers Into Diagnoses"
Early diagnosis is a key factor in the prevention and management of rheumatic diseases. Rheumatic diseases are classically diagnosed based on criteria combining clinical, biological and radiological features.
- Trial name
- ARTBioSes (NCT06312943)
- Testing
- Collection of joint fluid or tissue sample
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Pain, Rheumatoid Arthritis
Effects of Virtual Reality on Brain Hemodynamic Activity in Chronic Pain
Virtual reality systems have been applied in recent years to reduce pain intensity and fear of movement in individuals with acute and chronic pain.
- Conditions
- Chronic Pain, Rheumatoid Arthritis, Virtual Reality
- Trial name
- NCT06154850
- Testing
- Immersive virtual reality, Non-immersive virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Acibadem University
Rheumatoid Arthritis, Arthritis, Rheumatoid
Educational Intervention to Improve Patient-Physician Awareness of Cardiovascular Risk in Rheumatoid Arthritis.
This study will provide an educational intervention through means of a video to educate subjects on the risk of cardiovascular health on Rheumatoid arthritis.
- Trial name
- NCT03495791
- Testing
- YouTube Video
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Rush University Medical Center
Arthritis, Rheumatoid
ULTRACET (Tramadol Hydrochloride and Acetaminophen) for the Treatment of Rheumatoid Arthritis Pain.
The purpose of this study is to assess the effectiveness of ULTRACET® (a combination analgesic) as add-on therapy in rheumatoid arthritis patients taking an NSAID (e.g.
- Trial name
- NCT00246168
- Testing
- tramadol hydrochloride + acetaminophen
- Volunteers
- 277 people
- Sponsor
- Janssen Korea, Ltd., Korea
Rheumatoid Arthritis
An Open-label Extension Study Evaluating the Safety and Efficacy of Upadacitinib (ABT-494) in Adults With Rheumatoid Arthritis
The primary objective of the study is to evaluate the long-term safety, tolerability, and efficacy of upadacitinib in adults with rheumatoid arthritis (RA) who have completed a preceding randomized controlled trial with…
- Trial name
- BALANCE-EXTEND (NCT02049138)
- Testing
- Upadacitinib, Pneumococcal 13-valent conjugate vaccine (PCV-13)
- Where
- 124 sites in United States, Belgium and 16 more
- Volunteers
- 493 people
- Sponsor
- AbbVie
Osteoarthritis, Rheumatoid Arthritis
Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501, a fixed-dose combination oral tablet of 800 mg ibuprofen and 26.6 mg famotidine for patients that require long-term NSAID treatment.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- NCT00984815
- Testing
- HZT-501
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Amgen
Rheumatoid Arthritis
Laser Acupuncture in Rheumatoid Arthritis Geriatric Patients
Studying the effect of laser acupuncture on geriatric patients with rheumatoid arthritis
- Trial name
- NCT04758689
- Testing
- Laser, exercise, and methotrexate, Exercise, and methotrexate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Rheumatoid Arthritis
Clinical Trial to Compare Treatment With GP2017 and Humira® in Patients With Rheumatoid Arthritis
Clinical trial to compare treatment with GP2017 and Humira® in patients with Rheumatoid Arthritis
- Trial name
- ADMYRA (NCT02744755)
- Testing
- Adalimumab - GP2017, Adalimumab - US licensed Humira
- Where
- 83 sites in United States, Czechia and 11 more
- Volunteers
- 353 people
- Sponsor
- Sandoz
Rheumatoid Arthritis
Efficacy and Safety Study of MK0359 in Patients With Arthritis (0359-017)
Efficacy and Safety Study of MK0359 in Patients with Arthritis
- Trial name
- NCT00482417
- Testing
- MK0359
- Volunteers
- 11 people
- Sponsor
- Merck Sharp & Dohme LLC
Arthritis, Rheumatoid
Study Of 90mg Of GW274150 In Subjects Over 50 Years, Who Have Rheumatoid Arthritis (RA)
This is a study of GW274150, an iNOS (inducible nitric oxide synthase) inhibitor to investigate safety, tolerability and pharmacokinetics (PK) in the rheumatoid arthritis (RA) population (greater than 50 years).
- Trial name
- NCT00370435
- Testing
- GW274150
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- GlaxoSmithKline
Rheumatoid Arthritis
Italian Registry of Arthritis on Biologic Therapy
The biologic drugs targeting TNFa, IL-6, IL-1, T cells, B cells have represented a fundamental discovery to treat rheumatic patients whose disease appears to be refractory to conventional therapy.
- Trial name
- GISEA (NCT01543594)
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Gruppo Italiano Studio Early Arthritis
Rheumatoid Arthritis, Psoriatic Arthritis
Mindfulness Based Stress Reduction in Rheumatic Diseases
This study will assess the mental health and clinical benefits of Mindfulness Based Stress Reduction (MBSR) in patients with rheumatic disease who have anxiety or depression.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Scleroderma
- Trial name
- MBSR (NCT03411057)
- Testing
- Mindfulness Based Stress Reduction (MBSR), Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Rheumatoid Arthritis (RA)
Validity And Reliability Of The Four Square Step Test In Individuals With Rheumatoid Arthritis
This cross-sectional observational study aims to evaluate the validity and reliability of the Four Square Step Test (FSST) in individuals with rheumatoid arthritis.
- Trial name
- NCT07264101
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Inonu University
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