Clinical trials: RhA - Rheumatoid Arthritis
Rheumatoid Arthritis, Healthy Controls
Subunit Vaccine Against Herpes Zoster in RA Patients Treated With JAK-inhibitors (VACCIMIL-ZOSTER)
Background. A new subunit vaccine against herpes zoster (HZ) has recently been approved for vaccination of adults i in Sweden. This vaccine (Shingrix) elicits a strong cellular and humoral immune response in healthy adults…
- Trial name
- NCT03886038
- Testing
- Shingrix
- Where
- Sweden
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Region Skane
Osteoarthritis, Rheumatoid Arthritis
Reciprocating Medical Devices - a Study of a New Safety Device
The study design is a randomized study to directly compare the performance and the outcome of syringe and needle procedures with a standard syringe or the new reciprocating procedure device (RDP), which is a type of safety…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Trauma, Thyroid Nodule
- Trial name
- RPD (NCT00651625)
- Testing
- Reciprocating Procedure Device (RPD) - AVANCA Re No. 1091001, conventional syringe - BD Ref 309604
- Where
- United States
- Volunteers
- 437 people
- Sponsor
- University of New Mexico
Rheumatoid Arthritis (RA, Psoriatic Arthritis (PsA
Efficacy Of Upadacitinib In Psoriatic Arthritis And Comparison To Rheumatoid Arthritis.
The general objective of the OPTIMA study is to assess the time course and interrelationship of imaging (ultrasound and magnetic resonance imaging), clinical, laboratory, and Patient Reported Outcome variables in patients with…
- Trial name
- OPTIMA (NCT06630715)
- Testing
- Upadacitinib 15 MG [Rinvoq]
- Where
- 14 sites in Italy
- Volunteers
- 178 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Rheumatoid Arthritis
Intra-articular Injection of Etanercept in Patient Suffering From Rheumatoid Arthritis : a Double-blind Randomized Study
Intra-articular injection of etanercept in patient suffering from rheumatoid arthritis: a double-blind randomized study for evaluation of efficacy and safety of etanercept versus intra-articular steroid injection in acute…
- Trial name
- NCT00522184
- Testing
- intra-articular injection of etanercept, intra-articular injection of steroid
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Rheumatoid Arthritis, Osteoarthritis
Effect of Exercise Type on Muscle Quality in Patients With OA, SARC and RA: an Explorative Study
C4M hypothesizes that patients with low muscle strength may respond differently to different types of exercise intervention, dependent on the underlying aetiology, i.e.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Sarcopenia
- Trial name
- C4M (NCT06480643)
- Testing
- High load exercise type, Low load exercise type
- Volunteers
- 69 people
- Sponsor
- Amsterdam UMC, location VUmc
Rheumatoid Arthritis
Evaluation of Long-term Safety and Effectiveness of Fostamatinib in the Treatment of Rheumatoid Arthritis (RA)
The purpose of this study is to evaluate the long term safety and tolerability of fostamatinib in patients with rheumatoid arthritis (RA).
- Trial name
- OSKIRA-X (NCT01242514)
- Testing
- Fostamatinib
- Where
- 308 sites in United States, Argentina and 29 more
- Volunteers
- 1,917 people
- Sponsor
- AstraZeneca
Rheumatoid Arthritis
China Rheumatoid Arthritis Registry of Patients With Chinese Medicine
A multi-center registration study of clinical characteristics of rheumatoid arthritis (RA) patients with Chinese medicine.
- Trial name
- CERTAIN (NCT05219214)
- Testing
- Chinese medicine
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Arthritis, Rheumatoid, Bone Erosion
Identification of Novel Molecular Targets for Rheumatoid Arthritis Patients
Aims of this study is to identify the mechanisms of the dissociation between the inflammatory activity and the joints destruction in patients with rheumatoid arthritis (RA) in remission but presenting a progression of the bone…
- Trial name
- NCT04201535
- Testing
- Protein arrays on plasma samples
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Rheumatoid Arthritis
Registry of Etanercept Use in Patients With Rheumatoid Arthritis in Clinical Practice in Taiwan
The purpose of this study is to develop a registry with safety and efficacy data on the use of etanercept in clinical practice in Taiwan.
- Trial name
- NCT00888576
- Where
- 23 sites in Taiwan
- Volunteers
- 441 people
- Sponsor
- Pfizer
Rheumatoid Arthritis, Rheumatic Diseases
Relationship Between Rheumatoid Arthritis Severity and Cognition in the Elderly: The Role of Nociplastic Pain
this study aims to determine if nociplastic pain mediates the relationship between rheumatoid arthritis (RA) severity and cognitive impairment in geriatric patients 100 patients aged 65-90 years with long-standing RA and assess…
- Conditions
- Rheumatoid Arthritis, Rheumatic Diseases, Rheumatoid Polyarthritis
- Trial name
- NCT05934721
- Testing
- Questionnaire and physical assessments
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahram Canadian University
Rheumatoid Arthritis, Ankylosing Spondylitis
Assessment of Treatment Safety and Quality of Life in Patients Receiving Etanercept Biosimilar for Autoimmune Arthritis
In this open-label, multi-center, observational, post-marketing surveillance study, patients with ankylosing spondylitis, psoriatic arthritis, or rheumatoid arthritis received biosimilar etanercept 25 mg twice weekly or 50 mg…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- ASQA (NCT04582084)
- Testing
- Etanercept
- Where
- 10 sites in Iran
- Volunteers
- 583 people
- Sponsor
- AryoGen Pharmed Co.
Rheumatoid Arthritis
Enhancing Patient Ability to Understand and Utilize Complex Information Concerning Medication Self-management
The aim of the proposed project is to compare the effectiveness of two strategies designed to enhance patient understanding of medication risks/benefits: (1) Medication Guides, mandated for many medications by the Food and Drug…
- Trial name
- NCT02820038
- Testing
- Medication Guides, SMART Program, Drug Facts Boxes
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- University of North Carolina, Chapel Hill
Rheumatoid Arthritis
Study of NI-071 in Comparison With Remicade in Patients With Rheumatoid Arthritis
The purpose of this study is to compare the safety of NI-071 with Remicade® (infliximab) in patients with Rheumatoid Arthritis inadequately treated with Methotrexate.
- Trial name
- NCT01567358
- Testing
- Infliximab
- Where
- Japan
- Volunteers
- 14 people
- Sponsor
- Nichi-Iko Pharmaceutical Co., Ltd.
Rheumatoid Arthritis
The Effects of Acthar on Synovial Inflammation in Rheumatoid Arthritis
Patients will be assigned to receive either Depo Medrol or Acthar treatment. A synovial biopsy, blood draws, synovial fluid aspiration, and physician assessments will be performed before and after initiating treatment.
- Trial name
- NCT03511625
- Testing
- Acthar Injectable Product, Depo medrol
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Attune Health Research, Inc.
Rheumatoid Arthritis
A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX
This randomized, multicenter, double-blind, parallel group study will evaluate the impact of MTX discontinuation on the efficacy of SC TCZ in participants with moderate to severe active rheumatoid arthritis who have an inadequate…
- Trial name
- NCT01855789
- Testing
- Tocilizumab (TCZ), Methotrexate (MTX)
- Where
- 155 sites in United States
- Volunteers
- 718 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to Methotrexate
Study in participants with RA who have an inadequate response to methotrexate.
- Trial name
- NCT00950989
- Testing
- Brodalumab, Methotrexate, folic acid
- Volunteers
- 252 people
- Sponsor
- Amgen
Rheumatoid Arthritis
Exploiting Leading Edge 7T MRI Brain Imaging to Decipher Olumiant's Mode of Analgesic Action in Rheumatoid Arthritis
The revolution in treatments for rheumatoid arthritis (RA) has transformed patient outcomes, but many patients continue to experience life disabling pain.
- Trial name
- SOAR (NCT05112120)
- Testing
- Olumiant
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- NHS Greater Glasgow and Clyde
Rheumatoid Arthritis
Assessment of Leflunomide Efficacy and Hepatotoxicity in Patients With Rheumatoid Arthritis Through Pharmacokinetic and Genetic Approaches
The RA patients receiving leflunomide for more than one month, and not receiving other DMARDs (except hydroxychloroquine), will be enrolled to assess their disease activity.
- Trial name
- NCT04022525
- Testing
- Leflunomide 20Mg Tab
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Rheumatoid Arthritis
Feasibility of a Cytokine Expression Profile in Immune Cells as an Orientation Tool in Therapeutic Decisions for Auto-inflammatory and Auto-immune Diseases
This study will assess the feasibility of using cytokine expression profiles in blood samples as a method for evaluating rheumatoid polyarthritis
- Trial name
- IL-MAI (NCT03280797)
- Testing
- Blood sample
- Where
- 2 sites in France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Arthritis, Rheumatoid
Bone MicroArchitecture Abatacept (BMA2)
Rheumatoid Arthritis patients management reposes primarily on the use of disease-modifying antirheumatic drugs (DMARDs). Among DMARDs available in 2015, researchers demonstrated the ability to reduce synovitis, biomarkers of…
- Trial name
- BMA2 (NCT02675218)
- Testing
- Patients with rheumatoid arthritis
- Where
- 5 sites in France
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
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