Clinical trials: RhA - Rheumatoid Arthritis
Rheumatoid Arthritis
Relationship Between Grip Endurance, Disability of Upper Extremity and Quality of Life in Patients With RA
The aim of this study is to investigate the relationship between grip endurance, disability of upper extremity and quality of life in patients with rheumatoid arthritis.
- Trial name
- NCT04563455
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Izmir Katip Celebi University
Rheumatoid Arthritis
RA Denosumab on Bone Microstructure Study
The aim of this study is to compare the effects of denosumab and a current standard treatment on cortical and trabecular microarchitecture at the radius and second metacarpal in rheumatoid arthritis (RA) patients with low bone…
- Trial name
- NCT01770106
- Testing
- Denosumab, Alendronate
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Healthy
Pharmacokinetics And Tolerability Of Subcutaneous Administration Of PF 04236921 In Healthy Volunteers
This study will evaluate the safety, tolerability, and pharmacokinetics of PF-04236921 administered as a single subcutaneous dose in healthy volunteers.
- Trial name
- NCT01166555
- Testing
- PF-04236921
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pfizer
Rheumatoid Arthritis
Safety and Effectiveness of Infliximab in Slovakia When Used for Rheumatoid Arthritis (Study P04741)(COMPLETED)
This study will gather information on the safety and efficacy of patients with rheumatoid arthritis (RA) who are starting treatment with infliximab for the first time.
- Trial name
- NCT00724243
- Testing
- Infliximab
- Volunteers
- 33 people
- Sponsor
- Merck Sharp & Dohme LLC
Rheumatoid Arthritis, Psoriasis Arthritis
Prospective Evaluation of the Radiographic Efficacy of Enbrel
It is known from the COMET-trial that patients who start Enbrel treatment early have a great chance of reaching clinical remission and radiographic nonprogression.
- Trial name
- PRERA (NCT01623752)
- Testing
- Etanercept
- Volunteers
- 1,821 people
- Sponsor
- Pfizer
Rheumatoid Arthritis
To Evaluate The Effect Of SAR153191 (REGN88) Added To Other RA Drugs In Patients With RA Who Are Not Responding To Or Intolerant Of Anti-TNF Therapy (SARIL-RA-TARGET)
Primary Objective: To demonstrate that sarilumab added to disease modifying anti-rheumatic drugs (DMARDs) were effective for: reduction of signs and symptoms at Week 24 and improvement of physical function at Week 12 in…
- Trial name
- NCT01709578
- Testing
- Sarilumab, hydroxychloroquine, methotrexate
- Where
- 196 sites in United States, Argentina and 28 more
- Volunteers
- 546 people
- Sponsor
- Sanofi
Rheumatoid Arthritis
Better After CHoosing. Randomly Allocated or Patient Preference Based Treatment With Filgotinib or TNFi in RA (BACH)
Despite their efficacy in the treatment of Rheumatoid Arthritis and their partial advantage over traditional bDMARDs ( biological Disease Modifying antirheumatic drugs), JAK inhibitors (JAKi or tsDMARDs) have not gained…
- Trial name
- BACH (NCT04985435)
- Testing
- Filgotinib, Anti-Tumor Necrosis Factor Alpha Drug (Product), 50 patients will have a Free Choice between Filgotinib and anti TNF
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- R.Bos
Cardiovascular Diseases, Rheumatoid Arthritis
Comprehensive Assessment of Subclinical Atherosclerosis in Patients With Rheumatoid Arthritis
Cardiovascular disease is a leading cause for morbidity and mortality in general population. The incidence of cardiovascular disease and their poor outcome is well documented in a broad spectrum of connective tissue diseases…
- Conditions
- Cardiovascular Diseases, Rheumatoid Arthritis, Atherosclerosis, Coronary
- Trial name
- NCT03813017
- Volunteers
- 100 people
- Sponsor
- Ziv Hospital
External Causes of Morbidity and Mortality
Longterm Followup of Patients With Rheumatoid Arthritis Treated With Methotrexate
Longterm followup of patients with rheumatoid arthritis 30 years after starting a baseline treatment with Methotrexate.
- Trial name
- MTX (NCT02641977)
- Where
- Germany
- Volunteers
- 271 people
- Sponsor
- Ruhr University of Bochum
Rheumatoid Arthritis
Evaluation of Tabalumab Using Auto-Injector or Prefilled Syringe in Participants With Rheumatoid Arthritis (RA)
The purpose of this study is to evaluate the serum concentration of tabalumab after the administration using either prefilled syringe or auto-injector after the initial loading dose and after 12 weeks of treatment.
- Trial name
- NCT01676701
- Testing
- Tabalumab Auto-Injector, Tabalumab Prefilled Syringe
- Where
- 37 sites in United States, Argentina and 4 more
- Volunteers
- 8 people
- Sponsor
- Eli Lilly and Company
Rheumatoid Arthritis
A Study of the Efficacy and Safety of Tocilizumab for Confirmed Rheumatoid Arthritis (RA) Participants in Clinical Practice
This is a single-arm, open-label, non-randomized, multicenter trial to evaluate the efficacy and safety of using tocilizumab for confirmed rheumatoid arthritis participants in clinical practice.
- Trial name
- NCT02616328
- Testing
- No intervention
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 8 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor
This study will evaluate the efficacy and safety of MabThera in patients with active rheumatoid arthritis who have had an inadequate response to one prior anti-TNF alpha inhibitor.
- Trial name
- NCT02079532
- Testing
- rituximab [MabThera]
- Where
- 69 sites in Germany
- Volunteers
- 302 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Reconstitution of CD4+CD25highCD127low/-Tcell
Rheumatoid arthritis (RA) is a systemic disabling inflammatory disease, of autoimmune origin characterized by chronic synovial inflammation resulting in joint damage.
- Trial name
- NCT03736044
- Testing
- TNF-blockers suspension in patients with rheumatoid arthritis
- Volunteers
- 48 people
- Sponsor
- University Hospital of Ferrara
Rheumatoid Arthritis
Uromodulin in Rheumatoid Arthritis
The aim of the present study was to evaluate the levels of uromodulin in rheumatoid arthritis (RA) and to investigate whether it was correlated with baseline clinical characteristics.
- Trial name
- NCT03972098
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- neval aksoy
Rheumatoid Arthritis
The Effect of Distant Reiki Application on Pain, Functional Status and Sleep Quality
Rheumatoid Arthritis (RA) is a chronic, multisystemic, progressive autoimmune disease characterized by joint destruction in synovial tissue, causing joint swelling, pain and morning stiffness.
- Trial name
- NCT05861934
- Testing
- Distant reiki group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Aksaray University Training and Research Hospital
Rheumatic Disease
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty
The purpose of this study is to assess the incidence of rheumatologic flares, changes in pain scores (VAS), changes in functional outcomes (PROMIS), wound complications, surgical site infections, and return trips to the operating…
- Trial name
- NCT07138898
- Testing
- Methotrexate, Sulfasalazine, Hydroxychloroquine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- NYU Langone Health
Rheumatoid Arthritis, Depression
Depression and Anxiety in Rheumatoid Arthritis
The primary endpoint of this study is to evaluate the prevalence of anxiety and depressive disorders, and their relationship with disease activity, in patients with rheumatoid arthritis treated with biological drugs
- Conditions
- Rheumatoid Arthritis, Depression, Anxiety
- Trial name
- DEAR (NCT02122406)
- Testing
- Hospital Anxiety and Depression Scale (HADS) questionnaire
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Pavia
Arthritis, Rheumatoid
Determine the Improvement in Activity Status/Quality of Life (QoL) of Patients With Rheumatoid Arthritis (RA) During Treatment With Lodotra (Prednisone)
Rheumatoid arthritis is the most common rheumatic disease with symptomatic morning stiffness which entails a quite essential restriction in the everyday life and in the life quality.
- Trial name
- LODOTRA (NCT01075711)
- Testing
- Prednisone
- Where
- Germany
- Volunteers
- 2,728 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Rheumatoid Arthritis
Marine Oils and Arthritis
NSAIDS are associated with adverse GI effects and COX-2 inhibitors have cardiovascular risk. Long-term oral supplementation with fish oil reduce e.g.
- Trial name
- NCT00805116
- Testing
- Whale blubber oil, Cod liver oil
- Volunteers
- 7 people
- Sponsor
- National Institute of Nutrition and Seafood Research, Norway
Rheumatoid Arthritis
Evaluation of the Precision and Sensitivity of Tilmanocept Uptake Value (TUV) on Tc 99m Tilmanocept Planar Imaging
This clinical trial will look at scans of the hands and wrists taken from healthy control subjects (HCs) and from subjects with rheumatoid arthritis (RA).
- Trial name
- NCT03938636
- Testing
- Tc 99m tilmanocept
- Where
- 10 sites in United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Navidea Biopharmaceuticals
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