Clinical trials: RhA - Rheumatoid Arthritis
Rheumatoid Arthritis
A Study of P38 Inhibitor (4) Monotherapy in Patients With Active Rheumatoid Arthritis
This 4 arm study will compare the safety and efficacy, with regard to reduction of signs and symptoms, of P38 Inhibitor (4) (50, 150 or 300mg po qd) monotherapy versus methotrexate monotherapy in adult patients with active…
- Trial name
- NCT00303563
- Testing
- P38 Inhibitor (4)
- Where
- 61 sites in United States, Canada and 10 more
- Volunteers
- 204 people
- Sponsor
- Hoffmann-La Roche
Fatigue, Rheumatoid Arthritis
Fatigue in People With Rheumatoid Arthritis- Randomized Controlled Trial
Aim: To study if a person-centered physical therapy intervention program contributes to diminished fatigue in people with Rheumatoid Arthritis (RA).
- Trial name
- RAFatigueRCT (NCT02120963)
- Testing
- Person-centered physical therapy intervention program
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Göteborg University
Rheumatoid Arthritis
Cell Immunity Response to Vaccination Against Influenza in Patients With Rheumatoid Arthritis
The efficacy of vaccination against influenza in patients with rheumatoid arthritis has been assessed using humoral response. However, the cellular immunity is another important pathway of response to vaccination.
- Trial name
- NCT01002716
- Testing
- Agrippal S1 (Influenza vaccination)
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Herpes Zoster, Inflammatory Disease
The Immunogenicity and Safety of Zostavax® and Shingrix® in Rheumatoid Arthritis Patients Using Abatacept
This investigator-initiated study will serve as a sub-study for the American College of Rheumatology-sponsored VERVE protocol currently funded by the NIH.
- Conditions
- Herpes Zoster, Inflammatory Disease, Rheumatoid Arthritis
- Trial name
- BMS-188667 (NCT03604406)
- Testing
- Varicella Zoster Vaccine
- Where
- 5 sites in United States
- Volunteers
- 154 people
- Sponsor
- Kevin Winthrop
Rheumatoid Arthritis, Ankylosing Spondylitis
Impact of Air Pollution on the Course of Inflammatory Rheumatism
The objective of this study is to see if there is a link between air pollution and inflammatory rheumatism (rheumatoid arthritis and ankylosing spondylitis) To do this, the investigators are going to follow a cohort of about…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT05862584
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Rheumatoid Arthritis, Atherosclerosis
Effect of Sarilumab on Atherosclerotic Disease Assessed by PET/CET in Patients With RA (SARIPET)
Rheumatoid arthritis (RA) is a condition associated with a high incidence of cardiovascular disease (CV), primarily as a result of accelerated atherosclerosis .
- Trial name
- SARIPET (NCT04350216)
- Testing
- Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA]
- Volunteers
- 20 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Rheumatoid Arthritis (RA)
Plant-Based Diet for Patients With Rheumatoid Arthritis
The goal of this clinical trial is to evaluate the effect of a plant-based diet (PBD) intervention in adults with Rheumatoid Arthritis (RA) on disease activity.
- Trial name
- NCT07268326
- Testing
- Plant-based diet
- Where
- 2 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- Center for Clinical Research and Prevention
Rheumatoid Arthritis
Effects of Abatacept in Patients With Early Rheumatoid Arthritis
The purpose of this study is to determine if abatacept is effective in the treatment of early rheumatoid arthritis.
- Trial name
- AVERT-2 (NCT02504268)
- Testing
- Abatacept, Methotrexate
- Where
- 201 sites in United States, Argentina and 29 more
- Volunteers
- 994 people
- Sponsor
- Bristol-Myers Squibb
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Rheumatoid Arthritis, Ankylosing Spondylitis
Quality of Life Outcomes of HUMIRA in Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS) After Unsustainable Response to Biologicals and Disease Modifying Antirheumatic Drugs
The aim of this post-marketing observational study is to obtain further data on the evaluation of quality of life outcomes of HUMIRA® in routine clinical use in patients with Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA)…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT01083693
- Where
- 20 sites in Austria
- Volunteers
- 162 people
- Sponsor
- Abbott
Rheumatoid Arthritis
A Study Comparing CRx-102 Plus Disease-modifying Anti-rheumatic Drug (DMARD) Therapy to Placebo Plus DMARD Therapy in RA
This study was a Multicenter, Randomized, Blinded Study Comparing the Effect of CRx-102 Plus DMARD Therapy to that of Placebo Plus DMARD Therapy on Serum C Reactive Protein (CRP) and Cytokines in Subjects with Rheumatoid…
- Trial name
- NCT00747214
- Testing
- CRx-102, DMARD Therapy
- Volunteers
- 59 people
- Sponsor
- Zalicus
Rheumatoid Arthritis - Hand Joint
Patient Satisfaction After Silicone Metacarpophalangeal Arthroplasty
The primary objective of this study is to identify determinants of long-term patient satisfaction after hand reconstruction using silicone metacarpophalangeal arthroplasty (SMPA).
- Trial name
- NCT03626116
- Testing
- silicone metacarpophalangeal arthroplasty (SMPA)
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Schulthess Klinik
Rheumatoid Arthritis
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.
This single arm study will evaluate the safety and efficacy of MabThera in patients with active rheumatoid arthritis who are receiving methotrexate treatment, and who have had an inadequate response to one anti-TNF alpha therapy.
- Trial name
- NCT00576433
- Testing
- Methotrexate, rituximab [MabThera/Rituxan]
- Where
- 18 sites in Russia
- Volunteers
- 60 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Description of Joint Population and Assessment of Impact on Health Status of Orencia in Patients With Rheumatoid Arthritis in France. A Database Analysis Based on SFR's ORA Long-term Cohort Study
Database analysis: To describe how Orencia is prescribed in France in Rheumatoid Arthritis (RA) To describe joint population of Orencia To assess the impact of the treatment on health status of the treated population as assessed…
- Trial name
- NCT01694693
- Testing
- Orencia
- Sponsor
- Bristol-Myers Squibb
Rheumatoid Arthritis
Oral CF101 and Methotrexate Treatment in Rheumatoid Arthritis Patients
This trial will test the hypothesis that the addition of CF101, a novel anti-inflammatory agent, will improve the clinical condition of patients with rheumatoid arthritis who still have active joint inflammation despite taking…
- Trial name
- NCT00280917
- Testing
- CF101
- Where
- 35 sites in United States, Bulgaria and 5 more
- Volunteers
- 254 people
- Sponsor
- Can-Fite BioPharma
Rheumatoid Arthritis
Effect of Butyrate Supplement on Rheumatoid Arthritis
This study is a pilot study to evaluate the safety and efficacy of administering butyrate supplement on rheumatoid arthritis patients. Thirty participants will be included to receive butyrate supplement for 12 weeks.
- Trial name
- NCT05576597
- Testing
- Sodium Butyrate
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital
Rheumatoid Arthritis
Evaluating the Safety of Extended Treatment With Pegsunercept (PEG sTNF-RI)in Subjects With Rheumatoid Arthritis (RA)
The purpose of this study is to evaluate the safety of an additional 28 weeks of treatment with pegsunercept for subjects who have completed treatment in a previous double-blind study (20000201 or 20000198).
- Trial name
- NCT00111423
- Testing
- Pegsunercept (PEG sTNF-RI)
- Volunteers
- 216 people
- Sponsor
- Amgen
Systemic Sclerosis (SSc), Idiopathic Inflammatory Myopathy (IIM)
Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases
A Phase 1 study of HBI0101 BCMA-CART in B-Cell Mediated Autoimmune Rheumatic Diseases. The goal of the study is evaluation of safety and identification of the maximum HBI0101 CART dose that may be administered safely to patients…
- Conditions
- Systemic Sclerosis (SSc), Idiopathic Inflammatory Myopathy (IIM), Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE)
- Trial name
- NCT07085676
- Testing
- HBI0101 CART
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Polina Stepensky
Rheumatoid Arthritis
Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Rheumatoid Arthritis (RA)
This is a two part study comparing CHS-0214 to Enbrel in patients with active rheumatoid arthritis and an inadequate response with Methotrexate (MTX) who are naive to biologic therapies.
- Trial name
- CHS-0214-02 (NCT02115750)
- Testing
- Etanercept, CHS-0214
- Where
- 141 sites in United States, Belarus and 10 more
- Volunteers
- 647 people
- Sponsor
- Coherus Oncology, Inc.
Disease Activity
14.0- 3.0- 3.0- η Protein With Rheumatoid Arthritis
Aim of work: to explore the potential association between serum 14.0-3.0-3.0- η protein level with disease activity and bone mineral density (BMD) in Egyptian patients with rheumatoid arthritis (RA).
- Trial name
- NCT05366608
- Testing
- Serum level of 14.0- 3.0- 3.0- η protein and IL_.6
- Where
- Egypt
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Mansoura University
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