Clinical trials: RhA - Rheumatoid Arthritis
Osteoarthritis, Rheumatoid Arthritis
Clinical Investigation of the LCS® Complete Posterior Stabilized Mobile-bearing Total Knee System
Prospective, multi-center clinical study to evaluate the clinical outcomes of the posterior stabilized design of the LCS® Complete Mobile-bearing Total Knee System
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Juvenile Arthritis
- Trial name
- NCT00487565
- Testing
- Total knee arthroplasty
- Where
- 3 sites in United States
- Volunteers
- 210 people
- Sponsor
- DePuy Orthopaedics
Rheumatoid Arthritis
A Randomised, Double-blind, Phase I/II Study to Evaluate the PK, PD, Safety, and Efficacy Between HLX01 and Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis and Inadequate Response to Treatment With DMARDs
To compare the PK profiles of HLX01 and Rituximab in Chinese patients with moderate to severe rheumatoid arthritis.
- Trial name
- NCT03355872
- Testing
- HLX01
- Volunteers
- 194 people
- Sponsor
- Shanghai Henlius Biotech
Rheumatoid Arthritis
An Observational Study to Evaluate Safety and Efficacy of Remsima™ in Patients With RA
An Observational, Prospective Cohort Study to Evaluate Safety and Efficacy of RemsimaTM in Patients with Rheumatoid Arthritis.
- Trial name
- NCT02557295
- Volunteers
- 248 people
- Sponsor
- Celltrion
Wrist Morning Stiffness
Effectiveness of Kinesio Tape in Morning Stiffness and Functional Capacity in Patients With Rheumatoid Arthritis.
The purpose of this study is to determine how the applications of Kinesio Tape affect the morning stiffness in patients with rheumatoid arthritis.
- Trial name
- NCT02367157
- Testing
- Kenzo Kase Method, Kinesio Taping
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Diet Habit, Rheumatologic Disease
Rheumatology Diet Study
This study aims to collect information on rheumatology patients' dietary habits, autoimmune disease activity, dietary changes, disease symptom improvements, and perceptions on their dietary habits and how it affects their…
- Conditions
- Diet Habit, Rheumatologic Disease, Autoimmune Diseases, Rheumatoid Arthritis
- Trial name
- NCT06339957
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Central Florida
Rheumatoid Arthritis
Validation of the French Version of the Health Assessment Questionnaire II (HAQ-II) for Rheumatoid Arthritis
The purpose of the study is to develop a validated French version of the HAQ-II questionnaire for rheumatoid arthritis.
- Trial name
- HAQ-II (NCT03249467)
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Rennes University Hospital
Rheumatoid Arthritis, Periodontitis
Study of the Causal Link Between Rheumatoid Arthritis and Periodontitis Using Mendelian Randomization
This study aims to investigate the causal relationship between rheumatoid arthritis and periodontitis using Mendelian randomization.
- Trial name
- RAPD-MR (NCT06603207)
- Volunteers
- 220,000 people
- Sponsor
- Zhibin Xu
Rheumatoid Arthritis
Multiple Dose Study of UCB4940 as add-on to Certolizumab Pegol in Subjects With Rheumatoid Arthritis
The purpose of this study is to evaluate the safety, efficacy and body distribution of Bimekizumab (UCB4940) when added to Certolizumab Pegol treatment in patients with Rheumatoid Arthritis.
- Trial name
- NCT02430909
- Testing
- Bimekizumab, Certolizumab Pegol
- Where
- 21 sites in Czechia, Hungary and 5 more
- Volunteers
- 159 people
- Sponsor
- UCB Celltech
Rheumatoid Arthritis, Polyarticular Juvenile Idiopathic Arthritis
Comparison of PK and Tolerability of MSB11022 Administered by AI or PFS
The primary objective of this study is to demonstrate equivalence of the pharmacokinetic (PK) profile of MSB11022 administered by either an auto-injector (AI) or a pre-filled syringe (PFS) as single subcutaneous (s.c.) injection…
- Conditions
- Rheumatoid Arthritis, Polyarticular Juvenile Idiopathic Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis
- Trial name
- NCT04018599
- Testing
- 40 mg MSB11022
- Where
- 2 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Fresenius Kabi SwissBioSim GmbH
Rheumatoid Arthritis
SBD121, a Synbiotic Medical Food for RA Management
The aim of this randomised, double-blind, placebo controlled clinical food trial is to determine if the medical food SBD121 Synbiotic (prebiotic and probiotic) will aid in the dietary management of symptoms of early rheumatoid…
- Trial name
- NCT06005220
- Testing
- SBD121
- Where
- 22 sites in Australia, Bulgaria and 2 more
- Volunteers
- 143 people
- Sponsor
- Solarea Bio, Inc
Rheumatoid Arthritis
Effects of Kinesiotaping for Hands Function in Rheumatoid Arthritis
The aim of this research is to compare the effects of I-shape and fan shape kinesiotape techniques on pain, range of motion, grip strength and ADLs of patients with Rheumatoid Arthritis.
- Trial name
- NCT05039242
- Testing
- Conventional Physical Therapy), Kinesiotaping with I shaped application, Kinesiotaping with Fan-shaped Application
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Rheumatoid Arthritis
Inflammation and the Heart
Studies have shown that people with rheumatoid arthritis (RA) have a higher rate of heart disease than people that do not have RA. we believe this is caused by the inflammation produced by RA.
- Trial name
- NCT01589770
- Testing
- cardiac Magnetic Resonance imaging
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Rheumatoid Arthritis
An Open-Label Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis
This open-label, single-arm study will evaluate the efficacy and safety of tocilizumab in patients with active moderate to severe rheumatoid arthritis.
- Trial name
- NCT01951170
- Testing
- Tocilizumab
- Where
- 10 sites in Australia
- Volunteers
- 52 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
BIIB023 (Anti-TWEAK) in Subjects With Rheumatoid Arthritis
Phase I study designed to determine the safety and tolerability of a single dose of BIIB023 administered intravenously versus placebo to subjects with RA.
- Trial name
- NCT00771329
- Testing
- BIIB023
- Where
- 6 sites in United States, Russia
- Volunteers
- 53 people
- Sponsor
- Biogen
Osteoarthritis, Rheumatoid Arthritis
The Standard Care Versus Celecoxib Outcome Trial
The Standard Care versus Celecoxib Outcome Trial (SCOT) is a large streamline safety study designed to compare the cardiovascular safety of celecoxib versus traditional non-selective Non Steroidal Anti-Inflammatory Drug (NSAID)…
- Trial name
- SCOTLSSS (NCT00447759)
- Testing
- Celecoxib, Diclofenac
- Where
- 10 sites in Denmark, Netherlands and 1 more
- Volunteers
- 7,297 people
- Sponsor
- University of Dundee
Abnormality in Synovial Tissue
Examination of Biopsies From Healthy Knee Joints
The purpose of the project is to examine what kind of molecular mechanism which causes inflammatory joint diseases. This examination is carried out by a collection and analysis of synovial tissues for patients without…
- Trial name
- NCT02458170
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Rheumatoid Arthritis (RA), Inflammatory Bowel Disease - IBD1
Phase I Clinical Study of ZL-82 Tablets
ZL-82 is an oral janus kinase (JAK) inhibitor. In vitro biological mass spectrometry identification test proves that ZL-82 can selectively and irreversibly inhibit JAK3.
- Trial name
- NCT06055023
- Testing
- ZL-82 12.5mg, ZL-82 25mg, ZL-82 50mg
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Chengdu Zenitar Biomedical Technology Co., Ltd
Rheumatoid Arthritis
Tight Control of Disease Activity Among Patients With RA Based on a Systematic Telemedicine Treatment Strategy
The study aims to investigate the effect a systematic telemedicine intervention, based on the tigth control principals, as a platform for disease monitoring among patients with rheumatoid arthritis.
- Trial name
- TeRA (NCT02155894)
- Testing
- Disease control, Telemedicine, doctor, Disease control, Telemedicine, nurse
- Where
- 2 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- University of Aarhus
Rheumatoid Arthritis
Effect of Some Drugs on Rheumatoid Arithritis Activity
Effect of Some Drugs on Rheumatoid Arithritis Activity.
- Trial name
- NCT03770923
- Testing
- Rupatadine, Montelukast
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Sherief Abd-Elsalam
Rheumatoid Arthritis
An Observational Study of Dosage Patterns in Routine Clinical Practice in Patients With Rheumatoid Arthritis (ACT-LIFE)
This observational study will evaluate the dosage patterns, safety and efficacy of RoActemra/Actemra (tocilizumab) in clinical practice in patients with moderate to severe rheumatoid arthritis who have not responded or are…
- Trial name
- NCT01338545
- Where
- 48 sites in United States, Spain
- Volunteers
- 400 people
- Sponsor
- Hoffmann-La Roche
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