Clinical trials: Rheumatic Disorder
Osteoarthritis of the Knee
Effects of Aquamin F on NSAID Dose Reduction in Osteoarthritis of the Knee
The objective of this trial is to evaluate the effect of Aquamin F versus placebo on NSAID (non-steroidal anti-inflammatory drug) dose reduction in subjects with osteoarthritis of the knee.
- Trial name
- NCT00755482
- Testing
- Aquamin F
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Marigot Ltd.
Sjögren's Syndrome, Systemic Lupus Erythematosus
Objective Measurement With TCM Pattern for AIDDES
To explore the association with TCM pattern and TCM tongue diagnosis for Autoimmune disease and Dry eye syndrome.
- Conditions
- Sjögren's Syndrome, Systemic Lupus Erythematosus, Dry Eye Syndrome
- Trial name
- NCT04747288
- Testing
- Traditional Chinese Medicine pattern, Traditional Chinese Medicine tongue diagnosis, Heart rate variability
- Where
- Taiwan
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Osteoarthritis of the Knee
Effect Of Meloxicam Versus Placebo In Mainland Chinese Patients With Osteoarthritis Of The Knee
This study is to validate the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) tool in mainland Chinese patients with osteoarthritis of the knee .
- Trial name
- NCT01430559
- Testing
- Meloxicam
- Where
- 25 sites in China
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Study To Estimate The Amount Of CP-690,550 (Study Drug) That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of CP-690,550 In Tablet Form
In this study, a 10 mg dose of CP-690,550 will be given to study subjects on two separate occasions by two different routes of administration: One time by mouth in tablet form and one time by vein (intravenous form).
- Trial name
- NCT01143805
- Testing
- Tasocitinib 10 mg oral tablet, Tasocitinib 10 mg IV Infusion
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Osteoarthritis
Vascular Occlusion in Patients With Osteoarthritis
Resistance exercise plus vascular occlusion may induce greater improvements in strength and muscle mass than resistance training alone.
- Trial name
- NCT01483131
- Testing
- Exercise training, Resistance training with vascular occlusion
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Degenerative Arthritis
Combined Administration of Intravenous and Topical Tranexamic Acid in Total Knee Arthroplasty
This prospective randomized controlled trial was conducted To compare the efficacy of TNA in terms of total blood loss and the allogenic transfusion rate among the three study groups; intravenous alone, combined intravenous and…
- Trial name
- NCT02286973
- Testing
- Tranexamic Acid
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Total Knee Anthroplasty, Knee Osteoarthritis
IPACK vs Adductor Magnus Plane Block Added to Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty (TKA) is among the most frequently performed surgical procedures for degenerative joint diseases, including advanced knee osteoarthritis, rheumatoid arthritis, and post-traumatic arthritis.
- Conditions
- Total Knee Anthroplasty, Knee Osteoarthritis, Postoperative Pain Management
- Trial name
- NCT07643883
- Testing
- ACB+IPACK, ACB+AMM
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Osteoarthritis, Knee, Mobility Limitation
Effects of Improved Calf Muscle Function on Gait, Balance and Joint Loading in Older Adults
This study investigates the role of calf muscle function in gait performance, balance and knee joint loading. Previous studies have linked age-related loss of calf muscle function with impairments in gait performance and balance…
- Conditions
- Osteoarthritis, Knee, Mobility Limitation, Accidental Fall
- Trial name
- NCT03921801
- Testing
- Gait retraining, Gait retraining + strength training
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Fibromyalgia, Chronic Fatigue Syndrome
Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes.
This study will use brain Positron Emission Tomography/ Magnetic Resonance Imaging (PET/MRI) and an investigational radioactive drug called [Zr-89]oxine to track the location of white blood cells (also called leukocytes) in the…
- Conditions
- Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Healthy
- Trial name
- NCT03807973
- Testing
- [Zr-89]Oxine-labeled leukocytes PET/MRI
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis, Osteoarthritis, Knee
Reliability of Measuring Walking-related Performance Fatigability Using Six Minute Walk Test in Persons With Knee Osteoarthritis
Evidence has shown that knee osteoarthritis causes an increase in base of support and a decrease in stride length and gait velocity which results in an increase in energy expenditure during walking.
- Trial name
- NCT04530266
- Testing
- Six minute walk test
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Fibromyalgia
Acupuncture and Pain Processing
The purpose of this study is to test the hypothesis that acupuncture will reduce Fibromyalgia pain, via alterations in the processing of pain in the central nervous system.
- Trial name
- NCT01270607
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Osteoarthritis
Self-Management of Osteoarthritis
The purpose of this study is to examine whether a telephone-based self-management intervention improves pain, physical function, and other outcomes among veterans with osteoarthritis of the hip or knee.
- Trial name
- SeMOA (NCT00288912)
- Testing
- Health Education, Osteoarthritis Self-Management
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Fibromyalgia, Fibromyalgia (FM)
Feasibility and Preliminary Effects of an Asynchronous Microlearning Intervention on Fibromyalgia Knowledge Among Primary Health Care Workers
This randomized controlled pilot trial will evaluate the feasibility and preliminary effects of an asynchronous microlearning intervention on fibromyalgia knowledge among Primary Health Care workers.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome
- Trial name
- FIBROK-PILOT (NCT07865767)
- Testing
- Written Educational Material on Fibromyalgia, Asynchronous Microlearning Intervention on Fibromyalgia
- Where
- Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Instituto Neurociencia Del Dolor
Osteoarthritis
The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty
The purpose of this study is to use a new combination of anesthesia techniques in an attempt to minimize early pain after surgery and improve the patient's ability to participate more fully with physical therapy.
- Trial name
- NCT00620828
- Testing
- Ropivicaine 0.5%
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Duke University
Diabetic Peripheral Neuropathy, Fibromyalgia
Pharmacokinetics of Two Formulation of Pregabalin
A Randomized, Single-Dose, Parallel-Group Study to Evaluate the Pharmacokinetic Profiles of Two Formulations of Pregabalin after Oral Administration in Healthy Volunteers under Fasting Conditions
- Conditions
- Diabetic Peripheral Neuropathy, Fibromyalgia, Partial Seizure Disorder
- Trial name
- NCT03712475
- Testing
- Pregabalin
- Where
- Taiwan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Osteoathritis
Medial-Wedge Insole is Highly Effective in the Treatment of Valgus Knee Osteoarthritis
To assess the efficacy of medial-wedge insole in valgus knee osteoarthritis (OA). We hypothesized that medial-wedged insoles are biomechanically effective and should reduce lateral compartment loading in persons with valgus knee…
- Trial name
- NCT00467337
- Testing
- Medial-Wedge Insole intervention
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Fibromyalgia, Whiplash
Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain
Diffuse noxious inhibitory control In order to quantify central sensitization in chronic pain patients, the Diffuse Noxious Inhibitory Control (DNIC) model has been used frequently.
- Conditions
- Fibromyalgia, Whiplash, Chronic Pain
- Trial name
- NCT01172795
- Testing
- Relaxation session, Neurocognitive test battery
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Osteoarthritis, Knee
Clinical Outcomes of MP Persona vs. Persona Knee-PS
Knee osteoarthritis (OA) is a highly prevalent condition that results in substantial pain and loss of function. The end stage treatment for knee OA is total knee arthroplasty (TKA), a common and safe procedure typically performed…
- Trial name
- MP-Persona (NCT03681977)
- Testing
- Zimmer MP Persona, Zimmer Persona Knee-PS
- Where
- 3 sites in Canada
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Osteoarthritis, Traumatic Arthritis
Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee
The purpose of the study is to assess the long-term performance of the NexGen LPS-Flex Mobile Bearing Knee in the treatment of patients with severe knee pain or degenerative knee disease.
- Conditions
- Osteoarthritis, Traumatic Arthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus
- Trial name
- NCT00854295
- Testing
- NexGen LPS-Flex Mobile Bearing Knee
- Where
- 3 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
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