Clinical trials: Rheumatic Disorder
Knee Osteoarthritis
The Effectiveness of Virtual Reality Based Rehabilitation in Patients With Knee Osteoarthritis
We aimed to investigate the effects of virtual reality based rehabilitation program on patients with knee osteoarthritis.
- Trial name
- NCT04011553
- Testing
- Virtual Reality based Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Osteoarthritis, Knee, Arthroplasty
Comparison of Three Knee Replacements
The present randomized controlled trial is designed to compare one novel total knee replacement (TKR) design and two conventional TKR designs in terms of functional outcome.
- Conditions
- Osteoarthritis, Knee, Arthroplasty, Total Knee Replacement
- Trial name
- NCT03339557
- Testing
- NexGen, Persona, PFC
- Where
- Finland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Coxa, Hospital for Joint Replacement
Musculoskeletal Diseases, Osteoarthritis, Knee
Epidemiology and Nutrition
The general purpose of this study is to evaluate the relation between the nutritional status of patients, the features of the orthobiologics products used for patients' treatment and the clinical outcomes after one-step…
- Conditions
- Musculoskeletal Diseases, Osteoarthritis, Knee, Nutrition, Healthy
- Trial name
- Nutririsk (NCT05546541)
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Fibromyalgia
Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia
Fibromyalgia (FM) is a chronic pain condition that disproportionately impacts Veterans. Individuals diagnosed with FM patients experience lower self-esteem and positive affect, as well as greater levels of depression, anxiety…
- Trial name
- RAN (NCT06574165)
- Testing
- Moderate Intensity Continuous Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Osteoarthritis
Intra-Articular Injections of Platelet-Rich Plasma in Knee Osteoarthritis: Unique Application Versus Triple Application
The investigators include patients attending the outpatient clinic in the area of Orthopedics and Traumatology of the investigators hospital with a diagnosis of knee osteoarthritis, which treatment is medical.
- Trial name
- NCT02370420
- Testing
- Platelet-Rich Plasma, rehabilitation exercises
- Where
- Mexico
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Rheumatoid Arthritis
The Health Log: A Randomized Clinical Trial
The goal of the present study is to determine if a health management tool improves self-efficacy, satisfaction with the doctor's visit, and agreement of the statement "How satisfied are you that your concerns were addressed…
- Trial name
- NCT01913080
- Testing
- Health Log
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Rheumatoid Arthritis
Effects of Acute Exercise on BDNF Levels in Rheumatoid Arthritis Patients
Background: RA may progress with articular and non-articular involvement.Depression prevelance is found to increase for RA patients according to healthy population and to be correlated with pain, decreased quality of life…
- Trial name
- NCT04254146
- Testing
- Aerobic exercise
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Knee Osteoarthritis
The Effect Of Pulsed Electromagnetic Field And Progressive Resistance Exercise On Knee Osteoarthritis
The purpose of this study is to investigate the effect of pulsed electromagnetic field and progressive resistance exercise on Knee Osteoarthritis.
- Trial name
- NCT04106986
- Testing
- Pulsed electromagnetic field and Progressives resistance exercise, PRE
- Where
- Jordan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dyslipidemia, Diabetes
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Fructose-containing sugars have been implicated in the epidemics of obesity, diabetes and related cardiometabolic disorders. This view is supported by lower quality evidence from ecological observations, animal models, and select…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT02716870
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Depression, Osteoarthritis
Enhancing Well-Being Through Exercise During Old Age
Determine the feasibility of adapting Fit \& Strong!, an evidence-based group physical activity and health education program, to include affect and mood-related content and of employing this intervention among older adults with a…
- Trial name
- NCT04536727
- Testing
- Fit & Strong!, Wait list
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Osteoarthritis of Knee
Clinical Efficacy and Safety of NEOIAL HC for Intra-articular Use in the Treatment of Severe Knee Osteoarthritis
Osteoarthritis (OA) is one of the most frequent causes of pain and disability in adults. According to the Osteoarthritis Research Society International (OARSI), at least 40% of people over the age of 65 suffer from symptomatic…
- Trial name
- NCT05936762
- Testing
- Neoial HC
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nextrasearch S.r.l.s.
Uric Acid, Cardiovascular Diseases
Acute Effects of Tart Cherry on Uric Acid and Biomarkers of CVD Risk in Healthy Individuals
This study aims to provide evidence as to whether consumption of tart cherry juice can reduce the risk of gout and cardiovascular disease (CVD) in an acute context.
- Conditions
- Uric Acid, Cardiovascular Diseases, Gout
- Trial name
- NCT04960527
- Testing
- Tart cherry juice, Water
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Fibromyalgia
Effect of Low-impact Aerobic Exercise and Music Therapy in Fibromyalgia
The idea of this study is the combination of these two techniques (low-impact aerobic exercise through functional movements and music therapy) that have proven to be effective separately.
- Trial name
- EffMusFibro (NCT02516761)
- Testing
- Low-impact aerobic exercise combined with music therapy, Low-impact aerobic exercise, Control group
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Rheumatoid Arthritis
Comparative Pharmacokinetic Study of Three Abatacept Products in Male Normal Healthy Volunteers by the Subcutaneous Route
This is a randomised, double-blind, single dose, parallel groups study to compare the PK, immunogenicity, and safety of 3 abatacept products (DRL_AB, RP and RMP) in male NHV.
- Trial name
- NCT06126042
- Testing
- Test Product, Reference product, Reference Medicinal Product
- Where
- 3 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Osteoarthritis
Autologous Conditioned Plasma (ACP) Intra-articular (IA) Injections for Knee Osteoarthritis (OA)
This study is primarily investigating the effectiveness of Autologous Conditioned Plasma (ACP) Intra-articular (IA) in patients with Osteoarthritis (OA) in the knee.
- Trial name
- NCT02713542
- Testing
- ACP
- Where
- 4 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Arthrex, Inc.
Osteoarthritis, Knee
Antibiotic Loaded Bone Cement in Prevention of Periprosthetic Joint Infections in Primary Total Knee Arthroplasty
Introduction: The current evidence on the efficacy of Antibiotic Loaded Bone Cement (ALBC) in reducing the risk of periprosthetic joint infections (PJI) after primary joint reconstruction is insufficient.
- Trial name
- ALBA (NCT04135170)
- Testing
- ALBC vs plain bone cement
- Where
- Norway
- Volunteers
- 9,172 people, healthy volunteers welcome
- Sponsor
- The Norwegian Arthroplasty Register
Rheumatoid Arthritis
Study to Evaluate the Bioequivalence of Pfizer Korea Inc. "XELJANZ 5Mg Tablet" in Healthy Volunteers
This study is an open-label, randomized, fasted, single dose, crossover study to evaluate the bioequivalence of Chong Kun Dang Pharmaceutical "Chong Kun Dang Tofacitinib Tablet" and Pfizer Korea Inc.
- Trial name
- NCT03868072
- Testing
- XELJANZ 5Mg Tablet, Chong Kun Dang Tofacitinib Tablet
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Osteoarthritis, Ankylosing Spondylitis
15-Hydroxyprostaglandin Dehydrogenase in Osteoarthritis and Ankylosing Spondylitis
To evaluate serum and synovial fluid 15-PGDH levels in patients with osteoarthritis and ankylosing spondylitis and determine their associations with clinical and musculoskeletal ultrasound features.
- Trial name
- HPGD-OA-AS-US (NCT07751263)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Assiut University
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Fibromyalgia, Resilience
Fibromyalgia Severity: Role of Resilience and Family Dynamics
This cross-sectional survey study aims to examine the resilience and family dynamics between newly diagnosed fibromyalgia (FM) patients and healthy individuals.
- Trial name
- FSRRFD (NCT06777667)
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital