Clinical trials: Rheumatic Disorder
Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease
Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease
rheumatic heart disease remains the majority valvular disease in low and middle income countries, which mostly affected mitral valve, surgical treatment is the most effective strategy to improve the outcomes of middle or…
- Trial name
- NCT04780607
- Testing
- mitral valve repair
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Temporomandibular Degenerative Joint Disease
Topical Diclofenac Efficacy in Symptomatic Relief of Temporomandibular Degenerative Joint Disease
The use of a topical medication was compared to placebo to be applied over the symptomatic temporomandibular joint in women with the diagnosis of osteoarthritis of the temporomandibular joint(s).
- Trial name
- NCT00471393
- Testing
- 1.5% diclofenac in 45.5% DMSO (topical treatment)
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Osteoarthritis, Knee
The Effect of Exercise on Serum Levels of Collagen and Proteoglycan in Patients With Knee Osteoarthritis (EFEX-OA-01)
Aim of EFEX-OA-01: To explore how running, cycling and resting acutely influence levels of collagen and proteoglycan in patients with osteoarthritis knee and in young healthy subjects, as reflected by changes in serum and urine…
- Trial name
- EFEX-OA-01 (NCT04542655)
- Testing
- Ergometer Cycling followed by treadmill running, Treadmill Running followed by ergometer cycling, Rest
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nordic Bioscience A/S
Osteoarthritis, Knee
Standing Computed Tomography (SCT) Imaging of the Knee Joint
This study will help us decide the best way to image the knee for diagnostic purposes: Knee computed tomography vs knee x-ray. The computed tomography will provide a weight bearing 3D view.
- Trial name
- NCT03446404
- Testing
- Standing Computed Tomography
- Where
- United States
- Volunteers
- 826 people, healthy volunteers welcome
- Sponsor
- Neil A Segal
Osteoarthritis, Knee
Study of Various Insoles in Patients With Knee Osteoarthritis
It is critical to improve our understanding of knee osteoarthritis and to design better therapeutic options for this disease. The function of the knee during walking is an important factor in the development and progression of…
- Trial name
- NCT02530684
- Testing
- insole
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Osteoarthritis, Knee
Perineural Steroids for Peripheral Nerve Blocks
This study will look at the efficacy of dexamethasone for prolongation of peripheral nerve blocks.
- Trial name
- NCT02462148
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Anterior Uveitis (AU), Birdshot Chorioretinitis
Quantification & Classification of Inflammatory Cells in Uveitis Using OCT
The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of…
- Conditions
- Anterior Uveitis (AU), Birdshot Chorioretinitis, Behcet Disease, Herpes Simplex Virus
- Trial name
- NCT07065747
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Rheumatoid Arthritis, Inflammation
Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis
Recent studies show beneficial effect of the inhibition of interleukin-6 (IL-6) activity on vascular and left ventricular (LV) function.
- Trial name
- NCT03288584
- Testing
- Tocilizumab (Actemra®), Other biological agent, Corticosteroid and non-biological agents.
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Gout
Topical Application to Relieve Gout: Efficacy Trial & Safety (TARGETS)
This overall goal of this trial will be to demonstrate that DYV700 is safe and effective as a treatment for acute gout flares.
- Trial name
- TARGETS (NCT04130204)
- Testing
- DYV700, Colchicine 0.6 mg
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Dyve Biosciences, Inc.
Anxiety Disorders and Symptoms, Fibromyalgia
The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
Herbal Medicine is known as the medicinal use of herbal substances as a means of treating different conditions in the human body to ensure that the body remains in optimal health and wellness.
- Conditions
- Anxiety Disorders and Symptoms, Fibromyalgia, Arthritis, Chronic Pain
- Trial name
- NCT05067998
- Testing
- IV Vitamin Infused Therapy Treatment, Herbal medicine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Faith A. Richardson
Osteoarthritis
A Randomized, Double-Blind, Controlled Trial to Assess the Efficacy of a Fortetropin Supplement in Improving Symptoms of Osteoarthritis
This is a hybrid, double-blind, randomized, placebo-controlled clinical trial that will last 12 weeks. Participants will be randomized into either the intervention product or control group and will consume the test product or…
- Trial name
- NCT06021665
- Testing
- Fortetropin supplement, Cheese protein
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MYOS Corp
Rheumatoid Arthritis
Evaluation of Rheumatoid Arthritis Disease Education Literature
Rheumatoid arthritis is an inflammatory disease that results in joint inflammation, pain and swelling. It may progress to advance stages that render patients unable to carry out their daily activities.
- Trial name
- ERADEL (NCT03336684)
- Testing
- Patient education
- Where
- 2 sites in Pakistan
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Gout, Hyperuricemia
Research and Development of a New Technology for Detection of Abnormal Excretion of Intestinal Uric Acid Involved in the Incidence of Gout
To evaluate differences in specific SNPs and intestinal microflora between patients with gout and hyperuricemia and healthy controls.
- Conditions
- Gout, Hyperuricemia, Gut Microbiota, Uric Acid
- Trial name
- NCT04953533
- Testing
- no intervention
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Osteoarthritis, Knee
The Osteoarthritis Prevention Study
The goal of this study is to establish the efficacy of an intervention of dietary weight loss, exercise, and weight-loss maintenance for knee Osteoarthritis (OA) prevention in adult females aged ≥ 50 years with obesity and no or…
- Trial name
- TOPS (NCT05946044)
- Testing
- Diet and Exercise
- Where
- 4 sites in United States, Australia
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Arm, Rheumatic Diseases
Validity and Reliability of "Shriners Hospital Upper Extremity Evaluation" in Children With Rheumatic Disease
The most commonly used performance tests to evaluate upper extremity function in children diagnosed with rheumatic disease are the 9-hole peg test and Jebsen Taylor hand function tests.
- Conditions
- Arm, Rheumatic Diseases, Child, Only
- Trial name
- NCT04685434
- Testing
- Shriners Hospital for Children Upper Extremity Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Arthritis, Juvenile Rheumatoid
Safety and Efficacy of Measles, Mumps, Rubella Vaccination in Juvenile Idiopathic Arthritis
Background: The safety of vaccination in patients with autoimmune diseases using immune suppressive therapy is often discussed. Previous studies in Juvenile Idiopathic Arthritis (JIA) patients showed no increase in disease…
- Trial name
- VAART (NCT00731965)
- Testing
- Measles, Mumps, Rubella vaccination
- Where
- 5 sites in Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- N.M. Wulffraat
Fibromyalgia, Work Productivity
Evaluation of Work Productivity and Activities of the Fibromyalgia Patients' Relatives
Patients suffering from fibromyalgia (FM) are challenged by symptoms such as chronic pain, fatigue, sleep disturbance and emotional distress.
- Conditions
- Fibromyalgia, Work Productivity, Quality of Life, Pain, Chronic
- Trial name
- NCT06357793
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Dementia, Depression
Vegetarian Diet and Chronic Degenerative Diseases
To investigate the prospective association between a vegetarian diet and chronic degenerative diseases in two cohorts of Taiwanese Buddhists
- Conditions
- Dementia, Depression, Cardiovascular Diseases, Stroke
- Trial name
- NCT03470584
- Testing
- Diet Exposure
- Where
- Taiwan
- Volunteers
- 18,064 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Knee Osteoarthritis
Retro-walking in Knee Osteoarthritis
In osteoarthritis the most affected joint is knee due to degenerative changes. Degenerative changes cause age-related wear-and-tear and may be accelerated by injury, health and lifestyle factors, and possibly by genetic…
- Trial name
- NCT04546659
- Testing
- Retrowalking, Conventional Therapy
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Juvenile Idiopathic Arthritis
Oral Health, Saliva Bacteria, and Disease Activity in Children With JIA: A Cross-Sectional Study.
The goal of this observational study is to learn about the relationship between disease activity and oral health status in children with juvenile idiopathic arthritis (JIA).
- Trial name
- JIA (NCT07799831)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.