Clinical trials: Rheumatic Disorder
Sjogren's Syndrome
Assessment of Inflammatory Biomarkers Expressed in a Sjogren's Population: Effect of a Topical Steroid Intervention
The primary purpose of this study is to quantify the change in expression of biomarkers on the ocular surface of Sjogren's Syndrome participants after treatment with Maxidex.
- Trial name
- NCT00631358
- Testing
- Maxidex, No treatment
- Where
- 2 sites in Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Knee Osteoarthritis
Efficacy of Biodex Balance Training Versus Whole Body Vibration Training in Patients With Knee Osteoarthritis
This study will be conducted to answer the research question: Are there differences between the effect of Biodex balance training and Whole-body vibration training on Knee osteoarthritis?
- Trial name
- NCT06563258
- Testing
- Biodex Balance Training, A vibration device, traditional exercises
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Rheumatoid Arthritis
Uromodulin in Rheumatoid Arthritis
The aim of the present study was to evaluate the levels of uromodulin in rheumatoid arthritis (RA) and to investigate whether it was correlated with baseline clinical characteristics.
- Trial name
- NCT03972098
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- neval aksoy
Fibromyalgia
Respiratory Function in Fibromiyalgia Syndrome
Fibromyalgia is a condition that may lead to a decline in respiratory function, as well as impaired oxygen delivery to and utilization by the muscles-factors that contribute to fatigue and reduced exercise capacity.
- Trial name
- NCT07913126
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Osteoarthritis, Hip
Bone Marrow Aspirate Concentrate Use in Hip Osteoarthritis
The purpose of this study is to evaluate the effect of combined Bone marrow aspirate concentrate (BMAC) and Platelet Rich Plasma (PRP) action after a single hip intraarticular injection to young symptomatic patients with primary…
- Trial name
- BMAC (NCT03410355)
- Testing
- BMAC/PRP Injection, Cortisone Injection
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Osteoarthritis, Knee
A Comparison Between GLA:D Canada and an Individualized JointEffort Exercise Program in Knee Osteoarthritis Patients
Osteoarthritis (OA) is the leading cause of disability worldwide and affects more than 4.4 million people in Canada (13% of Canadians).
- Trial name
- NCT03406767
- Testing
- GLA:D Canada Program, JointEffort Program
- Where
- 4 sites in Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Knee Osteoarthritis, Knee Pain Chronic
The Effect of PEMF for Patients With Knee OA
Health care costs are increasing alarmingly, which will impose an overwhelming economic burden to an aging society like that of Hong Kong.
- Trial name
- NCT05548712
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis, Knee
Clinical Trial of YYD302 for Treatment of Osteoarthritis of the Knee
This is a multicenter, randomized, double-blinded, parallel, placebo-controlled, phase I/IIa clinical trial of YYD302 for treatment of osteoarthritis of the knee.
- Trial name
- NCT02965495
- Testing
- YYD302 2ml, YYD302 3ml
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Fibromyalgia, Depression
Effect of Physiotherapy Protocol in Treatment of Depression: Longitudinal Study
The purpose of his study is to investigate the effect of physiotherapy protocol in management of depression in patients with fibromyalgia and in patients with psychogenic depression.
- Trial name
- NCT05786677
- Testing
- Physiotherapy protocol, Selective serotonin reuptake inhibitors (SSRI)
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Cairo University
Rheumatoid Arthritis
Diagnostic Utility of Anti MCV Antibodies,Anti CCPantibodies and RF in RA
Rheumatoid arthritis (RA) is a chronic systemic disease affecting primarily the synovium, leading to joint damage and bone destruction(Gravallese E,2002).
- Trial name
- NCT03224377
- Testing
- anti mutated citrullinated vimentin antibodies
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rheumatoid Arthritis
NIR Fluorescence Imaging of Lymphatic Transport Using ICG
In this phase 1 study, the lymphatic transport will be examined using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities in healthy individuals using a MultiSpectral Imaging System (MSImager).
- Trial name
- NIR-ICG (NCT02680067)
- Testing
- Indocyanine Green, MultiSpectral Imaging System
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Osteoarthritis, Knee
Oral Steroid Taper After Total Knee Arthroplasty
This study aims to evaluate the effectiveness of an oral methylprednisolone taper in reducing postoperative pain, opioid consumption, and nausea following primary total knee arthroplasty (TKA).
- Trial name
- NCT07070882
- Testing
- Methylprednisolone
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Columbia University
Knee Osteoarthritis
Ketorolac Versus Triamcinolone Knee Injections for Osteoarthritis
Osteoarthritis is a disabling disease of the joint spaces and has a high impact on society due to the amount of people who are affected by the disease. Nonoperative management is a mainstay of therapy in most patients.
- Trial name
- NCT02295189
- Testing
- Ketorolac Tromethamine, Triamcinolone Acetonide
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Osteoarthritis, Knee
Estimate Serum Oxytocin PD Range in the Periphery
The main purpose of this study is to define the maximum effect oxytocin (naturally occurring hormone that is made in the brain) has on pain from a 5 minute heat probe applied to the skin and to get an estimate for the…
- Trial name
- NCT04431193
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Rheumatoid Arthritis, Bone Resorption
Differences in Bone Cell Activity Between Rheumatoid Arthritis and Ankylosing Spondylitis
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are characterized by chronic systemic inflammation and share common pathogenic pathways.
- Conditions
- Rheumatoid Arthritis, Bone Resorption, Ankylosing Spondylitis
- Trial name
- NCT01417455
- Where
- Portugal
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Instituto de Medicina Molecular João Lobo Antunes
Gulf War Illness, Persian Gulf War Syndrome
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
Determine if: genetic differences of CNDP1 gene the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents psychometric other variables can differentiate between veterans of the 1990-1991…
- Trial name
- NCT00810225
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Sjögren's Syndrome
Modulation of Immunity-related Gene Expression Under the Chinese Herbal Formula SS-1 Treatment for Sjögren's Syndrome
To evaluate the modulation of immunity-related gene expression for the Sjögren's syndrome under Chinese herbal medicine (SS-1) treatment.
- Trial name
- NCT02855658
- Testing
- SS-1
- Where
- 2 sites in Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Gout
NSAID Drug Interaction Study
This is a drug-drug interaction study in healthy volunteers to evaluate the potential pharmacokinetic (PK) effects of non-steroidal anti-inflammatory drugs on lesinurad and leinurad on the non-steroidal anti-inflammatory drugs.
- Trial name
- NCT01884272
- Testing
- lesinurad 400 mg, naproxen 250 mg, indomethacin 25 mg
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ardea Biosciences, Inc.
Rheumatoid Arthritis, Spondylitis, Ankylosing
Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases
Introduction: Patients with autoimmune rheumatic diseases (ARDs), rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PAs), ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), primary…
- Conditions
- Rheumatoid Arthritis, Spondylitis, Ankylosing, Spondyloarthritis, Systemic Lupus Erythematosus
- Trial name
- RZVRheum (NCT05879419)
- Testing
- Recombinant Herpes Zoster Vaccine (RZV), MTX Discontinuation, MMF Discontinuation
- Where
- Brazil
- Volunteers
- 2,005 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Fibromyalgia, Physical Function
The Role of Resilience for Physical Functioning of Patients With Fibromyalgia Syndrome Using the 6-Min Walk Test
Fibromyalgia (FM) is a prevalent chronic pain disorder, characterized by widespread musculoskeletal pain and fatigue that is associated with significant functional limitations. Its mechanisms are only partially understood.
- Conditions
- Fibromyalgia, Physical Function, Six-minute Walk Test
- Trial name
- 6MWT (NCT07611539)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Florida
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