Clinical trials: Rheumatic Disorder
Knee Osteoarthritis
Effects of a New Knee Brace for Treatment of the Knee Osteoarthritis
The purpose of this study is to evaluate the immediate effects of a knee brace with a new mechanism on the pain and medial knee loading during gait among medial knee osteoarthritis patients.
- Trial name
- NCT01866176
- Testing
- Stabilizing Knee Brace, Valgus Knee Brace, New Knee Brace
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Laval University
Rheumatoid Arthritis
Montelukast Use in Rheumatoid Arthritis
Montelukast is widely used in patients with asthma. Several preclinical data suggest that it could be repositioned as novel strategy for managing rheumatic patients by decreasing inflammatory mediators.
- Trial name
- NCT05447520
- Testing
- Montelukast, Conventional DMARDs
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Noha Mansour
Fibromyalgia
A Comparison of the Effect of Two Types of Whole Body Vibration on Fibromyalgia. A Randomized Controlled Trial.
The objective of this study is to compare the effectiveness of two types of body vibration platform, one vertical and one rotational, through a 12-week training in patients with fibromyalgia.
- Trial name
- NCT04128813
- Testing
- Vertical whole body vibration
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Osteoarthritis of Hip, Failure of Primary THA
Stability of Revision Total Hip Arthroplasty Implants Using Radiostereometric Analysis
The specific aim is to quantify the stability of the acetabular and femoral components of a revision total hip arthroplasty (THA) in vivo as currently performed at our institution.
- Trial name
- NCT01668160
- Testing
- Bead placement during revision hip replacement surgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Knee
The Treatment of Knee Osteoarthritis With Balanced Buttress Absorbable Spacer
The investigators randomly divided the knee osteoarthritis patients met the inclusive criteria into two groups (study group and control group).
- Trial name
- NCT03060382
- Testing
- balanced buttress absorbable spacer, total knee arthroplasty
- Where
- 2 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hebei Medical University Third Hospital
Osteoarthritis, Osteoarthritis, Knee
Medacta GMK Sphere® vs. Medacta GMK PS Post-Market Outcomes Study
The study is a prospective, randomized comparison of total knee arthroplasty with the Medacta GMK Sphere® knee compared to the Medacta GMK PS knee, with comparison to data from previous trials of similar study design.
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Joint Disease
- Trial name
- NCT03391323
- Testing
- Medacta GMK Sphere® Medial-Pivot Knee Prosthesis, Medacta GMK PS Posterior Stabilized Knee Prosthesis
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- David F. Scott, MD
Nasal Obstruction, Arthrosis
Role of Airtraq Mobile to Improve Intubation Conditions With Airtraq
Airtraq sp has been proven effective for intubating patients presenting with difficult airway. The Airtraq sp allows visualisation of the tracheal inlet only for the intubator.
- Trial name
- AirtraqMob (NCT02510924)
- Testing
- Tracheal intubation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Osteoarthritis of Hip
A Study of Posterior Hip Precautions After Total Hip Arthroplasty
The purpose of this study is to perform a randomized controlled study to compare patients undergoing THA via a posterolateral approach to receive either standard of care post-surgery hip restrictions or to receive no…
- Trial name
- HIPPRECAU (NCT03341442)
- Testing
- No hip precautions
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Fibromyalgia
Isometric Exercise and Endogenous Pain Inhibition
The purpose of this study is to identify the acute effects of isometric exercise on the inhibition of pain in individuals with fibromyalgia.
- Trial name
- NCT03778476
- Testing
- Isometric Exercise
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Marquette University
Arthritis, Rheumatoid, Healthy
Steroid Hormones, TH1/TH2 Cytokines and Reproductive Status
This study is designed to evaluate blood Th1 and Th2 immunoregulatory cytokine production and hormonal levels associated with the third trimester of pregnancy and the postpartum state.
- Conditions
- Arthritis, Rheumatoid, Healthy, Pregnancy
- Trial name
- NCT00001376
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Borderline Personality Disorder
Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.
- Trial name
- NCT01912391
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mood and Anxiety Research, Inc
Knee Osteoarthritis
Porous Baseplate in Total Knee Replacement
This is a multi-centre single cohort trial of patients undergoing cruciate-retaining total knee arthroplasty with the Advance Porous fixed bearing tibial baseplate and compatible femoral, patellar, and bearing components.
- Trial name
- NCT05226689
- Testing
- POROUS TIBIA BASEPLATE W/ JRNY LOCK
- Where
- 2 sites in Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Hip Osteoarthritis, Arthropathy of Hip
Total Hip Arthroplasty: Fast Track Protocol is the Future?
Fast-track total hip arthroplasty (THA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-H (NCT03875976)
- Testing
- Fast Track Protocol, Standard Care Protocol
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis
Developing Allogeneic Musculoskeletal Therapies
The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other…
- Trial name
- NCT06167928
- Where
- United Kingdom
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Keele University
Juvenile Idiopathic Arthritis, Familial Mediterranean Fever
Assessment of Cardiorespiratory Fitness Using the PACER in Patients With Juvenile Idiopathic Arthritis and Familial Mediterranean Fever
Juvenile Idiopathic Arthritis (JIA) and Familial Mediterranean Fever (FMF) are the most common autoimmune and autoinflammatory rheumatic diseases in childhood.
- Conditions
- Juvenile Idiopathic Arthritis, Familial Mediterranean Fever, Healty Controls
- Trial name
- NCT06697028
- Testing
- Usability and Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Fibromyalgia
Electrophysiological Findings in Fibromyalgia Patients
Fibromyalgia Syndrome (FMS); It is a chronic condition characterized by widespread body pain, sleep disturbance, fatigue, impaired cognitive functions, and anxiety (1).
- Trial name
- NCT04845737
- Testing
- sympathetic skin response measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Knee Osteoarthritis
Serum COMP and MMP-3 in Knee Osteoarthritis
Knee osteoarthritis is a common degenerative joint disease characterized by pain, stiffness, and functional limitation, significantly affecting quality of life.
- Trial name
- KOACOMP (NCT07528872)
- Testing
- Observational Study
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Fibromyalgia
Effectiveness of Myofascial Release Versus Manual Lymphatic Drainage After Breast Cancer Surgery
Objective. To compare the effectiveness of myofascial therapy against manual lymphatic drainage in the reduction of sequelae secondary to conservative surgery and radiotherapy in women who survived breast cancer. Design.
- Trial name
- MRvsMLD (NCT03182881)
- Testing
- Lymphatic Drainage, Myofascial Release
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
RA - Rheumatoid Arthritis
Pentacam Study of the Cornea in RA Patients
To evaluate the effect of rheumatoid arthritis (RA) activity on the corneal densitometry, corneal curvature (CC), central corneal thickness (CCT), and lens densitometry by Pentacam and compared these parameters with those of…
- Trial name
- NCT05241639
- Testing
- Pentacam
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Arthritis, Gouty
The MAD Study of SSGJ-613 in Healthy Subjects
To evaluate the safety and tolerability of SSGJ-613 after multiple subcutaneous injections in healthy subjects.
- Trial name
- NCT05966701
- Testing
- SSGJ-613
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
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