Clinical trials: Rheumatic Disorder
Rheumatoid Arthritis
Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio in Rheumatoid Arthritis
Rheumatoid arthritis is an autoimmune disease characterized by synovial inflammation and joint destruction that follows a relapsing- remitting course.Disease activity assessment is important for rheumatoid arthritis management…
- Trial name
- NCT03617250
- Testing
- Disease Activity Score-28
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Osteoarthritis, Knee
Pain Relief Effect of Low-intensity Continuous Ultrasound Stimulator for Knee Arthritis
The goal of this clinical trial is to test low-intensity continuous ultrasound stimulator(LICUS) for patients suffering from knee arthritis. it aims to evaluate the pain relief effect of LICUS.
- Trial name
- NCT05657535
- Testing
- Low-intensity continuous ultrasound stimulator
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kyu Jae Lee
Living Kidney Donation, Living Kidney Donor
Long-Term Risk of Gout in Living Kidney Donors
This population-based, matched, retrospective cohort study will evaluate the long-term risk of gout among living kidney donors compared with matched healthy nondonors, using linked administrative health care databases from…
- Conditions
- Living Kidney Donation, Living Kidney Donor, Gout, Gout and Hyperuricemia
- Trial name
- NCT07546643
- Testing
- Living kidney donation
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Knee Arthritis, Osteoarthritis, Bone Marrow Edema of the Knee
Extracorporeal Shock Wave Therapy in the Treatment of Periarticular Bone Marrow Edema in Patients With Knee Osteoarthritis
Bone marrow edema (BME) is a radiological finding characterized by increased fluid content and structural changes within the bone marrow. It most commonly affects weight-bearing joints such as the hip, knee, and ankle.
- Conditions
- Knee Arthritis, Osteoarthritis, Bone Marrow Edema of the Knee, Bone Marrow Edema
- Trial name
- NCT07887893
- Testing
- Radial Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Rheumatoid Arthritis, Tuberculosis
Comparison of the Tuberculin Skin Test (TST) and QuantiFERON ®-TB Gold Test (QFT-G) In Patients With Rheumatoid Arthritis Being Considered for Anti-TNF-Alpha Therapy
This research will help doctors interested in the usefulness of a new test to discover hidden tuberculosis infections in patients diagnosed with rheumatoid arthritis (RA). This new test is called Quantiferon-Gold (QFT-G).
- Trial name
- NCT00925249
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Patellofemoral Osteoarthritis
Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study
The purpose of this research is to develop and test the feasibility of an exercise intervention for persons with painful knee osteoarthritis involving the patella (kneecap).
- Trial name
- NCT02825238
- Testing
- Supervised exercise program
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
Osteoarthritis, Knee
NEO6860, a TRPV1 Antagonist, First in Human Study
This study is a double blind, placebo controlled, ascending single and multiple oral dose study conducted in two parts, aimed at determining the safety and tolerability of single and multiple oral doses of NEO6860 in healthy…
- Trial name
- NCT02337543
- Testing
- NEO6860
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Neomed Institute
Osteoarthritis, Knee
Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis
Knee osteoarthritis (KOA) is a common chronic painful musculoskeletal condition among older adults. It poses great challenge to the health care system due to its inability to be cured.
- Trial name
- NCT03628508
- Testing
- Exercise
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Primary Sjögren Syndrome
Neurotrophins Implications in Primary Sjögren Syndrome
Neurotrophins (NTs) constitute a family of growth factors, which regulated differentiation, proliferation, and survival of both neuronal cells and astrocytes.
- Trial name
- Neuro-SGSp (NCT01081184)
- Testing
- blood sample
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Osteoarthritis, Knee, Healthy
Generate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects
This is a study of participants that will receive an intravenous (IV) infusion of oxytocin (naturally occurring hormone that is made in the brain).
- Trial name
- NCT04431206
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Systemic Lupus Erthematosus, Sjogren's Syndrome
Mass Spectrometry-based Immune Profiling in Autoimmune Diseases
Based on mass spectrometry flow method, this study analyzed the typing of new T, B, NK and DC cell subsets in peripheral blood of common autoimmune diseases and their correlation with disease activity, aiming at establishing an…
- Conditions
- Systemic Lupus Erthematosus, Sjogren's Syndrome, Inflammatory Myopathies, Systemic Sclerosis (SSc)
- Trial name
- NCT07188285
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Osteoarthritis
Bilateral Total Knee Arthroplasty vs Unicompartment Arthroplasty Retrospective and Clinical Outcome Study
To determine if there is a patient satisfaction preference of Total Knee Arthroplasty (TKA) vs Unicompartmental Knee Arthroplasty (UKA) in patients with bilateral knee osteoarthritis who underwent a primary TKA one side and a…
- Trial name
- NCT02583113
- Testing
- Total and Unicompartment Knee Replacement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medacta USA
Rheumatic Disease
Safety and Immunogenicity of Sars-cov-2 Vaccine in Patients With Rheumatic Diseases
The purpose of this study was to preliminarily evaluate the immunogenicity of sars-cov-2 vaccine in patients with rheumatic diseases.
- Trial name
- NCT05191368
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yunnan University of Chinese Medicine
Rheumatoid Arthritis
Study of Some Risk Factors for Developing RA
Introduction Rheumatoid arthritis (RA), a chronic autoimmune disease of unknown etiology, .If not managed early , RA can result in irreversible, painful, and disabling joint damage.
- Trial name
- NCT03624179
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Juvenile Idiopathic Arthritis
Immersive Virtual Reality Exergaming Program in Adolescents Diagnosed With Juvenile Idiopathic Arthritis
The aim of the study is to investigate the effect of home-based exercise program versus personalized IVR exergame (Fit-XR) program on physical fitness, functional capacity and physical activity in adolescents with Juvenile…
- Trial name
- JiaFiT-XR (NCT06176846)
- Testing
- Immersive Virtual Reality Exergaming Program, Home-Based Exercise Program
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Osteoarthritis, Spinal Diseases
The Effect of AposTherapy on the Level of Pain, Function and Quality of Life in Patients With Neuro-muscular and Neurological Disorders
The purpose of the study is to examine the effect of a new biomechanical device and treatment methodology (AposTherapy) on gait patterns, pain, function and quality of life of patients with musculoskeletal and neurological…
- Conditions
- Osteoarthritis, Spinal Diseases, Ligament Rupture, Lower Extremity Fracture
- Trial name
- NCT01266382
- Testing
- AposTherapy
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Osteoporosis, Postmenopausal, Osteoarthritis, Knee
The Effect of High Impact Exercise on Bone and Articular Cartilage in Post-menopausal Women
Osteoarthritis (OA) and osteoporosis (OP) affect large numbers of the population. Around 8 million people in the UK are affected by OA and over 300,000 people present with fragility fractures in the UK each year.
- Conditions
- Osteoporosis, Postmenopausal, Osteoarthritis, Knee, BMD
- Trial name
- NCT03225703
- Testing
- Hopping
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Early Rheumatoid Arthritis
A Randomized Clinical Trial Evaluating the Efficacy of Clinical Pharmacist Assistance Along With Pharmaceutical and Non-pharmaceutical Therapy in the Early Rheumatoid Arthritis
Background: Rheumatoid arthritis (RA) is a progressive chronic autoimmune disease with a rising global burden, in which early diagnosis and timely therapeutic intervention are critical to preventing irreversible joint damage and…
- Trial name
- NCT07726355
- Testing
- Clinical Pharmacist Led Intervention, DMARD Therapy
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Deraya University
Fibromyalgia, Covid-19 Fear
The Effects of Covid-19 Pandemic on The Patients With Fibromyalgia
The investigators planned to analyze the effect of Covid-19 fear and anxiety on the daily life, sleep quality and depression-anxiety levels of fibromyalgia patients.
- Conditions
- Fibromyalgia, Covid-19 Fear, Covid-19 Anxiety, Daily Life
- Trial name
- NCT04686578
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809-T2
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214690
- Testing
- DW1809-T2, DW1809-1
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
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