Clinical trials: Rheumatic Heart Disease
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Overweight, Obesity
Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease
Since uncontrolled observational studies first linked fructose to the epidemic of obesity almost a decade ago, it has become a focus of intense concern regarding its role in the obesity epidemic and increasing burden of…
- Conditions
- Overweight, Obesity, Dyslipidemia, Hyperlipidemia
- Trial name
- NCT01608620
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Atrial Fibrillation, Rheumatic Heart Disease
Surgical Prevention of Atrial Fibrillation in Patients With Rheumatic Mitral Valve Lesion and Left Atrium Enlargement
This study evaluates the safety and efficiency of surgical prevention of atrial fibrillation in patients with valvular heart disease and left atrium enlargement
- Trial name
- NCT02474108
- Testing
- surgical prevention of atrial fibrillation, cardiomonitor
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Osteoarthritis
Balneotherapy and Echocardiographic Findings in Osteoarthritis
This prospective observational study aims to evaluate changes in heart function using echocardiography before and after a standardized balneotherapy program in adult and elderly patients with osteoarthritis.
- Trial name
- NCT06923969
- Testing
- balneotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Bursa City Hospital
Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease
Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease
rheumatic heart disease remains the majority valvular disease in low and middle income countries, which mostly affected mitral valve, surgical treatment is the most effective strategy to improve the outcomes of middle or…
- Trial name
- NCT04780607
- Testing
- mitral valve repair
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Hemoglobinopathies, Myelodysplastic Syndromes
Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload
This study will evaluate the change in cardiac iron load over a 53 week period measured by MRI in 2 cohorts of patients
- Conditions
- Hemoglobinopathies, Myelodysplastic Syndromes, Other Inherited or Acquired Anaemia, MPD Syndrome
- Trial name
- NCT00673608
- Testing
- deferasirox
- Where
- 4 sites in Australia
- Volunteers
- 118 people
- Sponsor
- Novartis
Knee Osteoarthritis
Safety of Electrotherapy in Patients With Knee Osteoarthritis and Cardiac Diseases
This study aimed to asses whether physyical therapy (e.g. electrotherapy in the form of low, medium or high frequency currents, massage and kinetotherapy) for treatment of knee osteoarthritis can induce or aggravate certain…
- Trial name
- NCT04148079
- Testing
- physical therapy
- Volunteers
- 46 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Neonatal Lupus, Systemic Lupus Erythematosus
The Research Registry for Neonatal Lupus
Women with lupus and other related disorders produce certain antibodies in the blood. Some women have these antibodies even if they have not yet developed symptoms of lupus or Sjogren's syndrome.
- Conditions
- Neonatal Lupus, Systemic Lupus Erythematosus, Sjogren's Syndrome, Congenital Heart Block
- Trial name
- NCT00074373
- Testing
- No intervention; observational
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Arthritis, Rheumatoid, Activities of Daily Living
Adaptation of EDAQ Into Turkish, Examining The Reliability and Validity For People With RA
The aim of the study is to adapt the Evaluation of Daily Activity Questionnaire into Turkish language, and to examine the reliability and validity for people with rheumatoid arthritis.
- Trial name
- NCT05244824
- Testing
- Adaptation into Turkish, Examining The Reliability and Validity for People with RA
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Fibromyalgia Syndrome
Palpitations and Tachycardia in Fibromyalgia Syndrome
Clinically Characterized by the presence of chronic widespread pan and tenderness, Fibromyalgia (FM) is one of the most common "functional" syndromes. FM is currently conceived of as representing a prototype of central pain, i.e.
- Trial name
- NCT01147263
- Testing
- Evaluation of autonomic parameters
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Fibromyalgia Syndrome
Unilateral and Bilateral taVNS in Fibromyalgia
This randomized controlled trial aimed to compare the effects of unilateral (left-sided) and bilateral transcutaneous auricular vagus nerve stimulation (taVNS) combined with a home exercise program on clinical outcomes, autonomic…
- Trial name
- taVNS-FMS (NCT07577102)
- Testing
- taVNS, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Gelisim University
Colon Cancer, Lung Cancer
Predictive Genetic Risk Assessment Trial
This proof-of-principle clinical trial at Mayo Clinic studies how patients and their physicians understand and utilize predictive genetic risk assessment.
- Conditions
- Colon Cancer, Lung Cancer, Atrial Fibrillation, Diabetes Type 2
- Trial name
- PGT (NCT00782366)
- Testing
- SNP analysis
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Fibromyalgia Syndrome
Auricular Acupuncture for Autonomic Balance and Pain in Fibromyalgia
This longitudinal study evaluates the effects of semi-permanent auricular acupuncture on the Autonomic Nervous System (ANS) activity and pressure pain threshold in adult female patients (aged 35-64) diagnosed with Fibromyalgia…
- Trial name
- NCT07641374
- Testing
- The needles will be applied to specific auricular points: Point Zero, Shen Men, Thalamus, and Master Cerebral Point.
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Italian Association for the Research and the Scientific Update
Right Ventricular Dysfunction, Rheumatic Heart Disease
Right Ventricular Echo Assessment in Mitral Valve Replacement
Rheumatic heart disease remains a major health problem in developing countries. It is the most important sequel of rheumatic fever and occurs in about 30% of patients with rheumatic fever.Rheumatic heart disease presents with…
- Trial name
- NCT03549052
- Volunteers
- 120 people
- Sponsor
- Assiut University
Cancer, Cancer Cachexia
A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss
The purpose of this study is to evaluate the safety and effectiveness of fish oil supplements in maintaining weight in people with disease-related weight loss and/or cachexia.
- Conditions
- Cancer, Cancer Cachexia, Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
- Trial name
- NCT00094562
- Testing
- Fish oil supplement
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Myocardial Inflammation, Rheumatoid Arthritis
Myocardial Inflammation in Rheumatoid Arthritis: A Descriptive Study
Rheumatoid arthritis (RA) patients have a higher prevalence of subclinical atherosclerosis than the general population. In addition, RA patients experience higher rates of heart failure with preserved ejection fraction (HFpEF).
- Conditions
- Myocardial Inflammation, Rheumatoid Arthritis, Coronary Artery Disease, Myocardial Strain
- Trial name
- NCT03776682
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Gonarthrosis, Knee Osteoarthritis
Efficacy of Craniosacral Therapy in Patients With Gonarthrosis
This randomized controlled trial was designed to investigate the effects of craniosacral therapy on pain, heart rate variability, joint stiffness, physical function, quality of life, body image, kinesiophobia, and dynamic balance…
- Trial name
- NCT07372534
- Testing
- Craniosacral Therapy, Home-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara Yildirim Beyazıt University
Rheumatic Heart Disease, Rheumatic Heart Disease in Children
Effectiveness of a School-centered Prevention Program on Prevalence of Latent Rheumatic Heart Disease
The overall objective is to evaluate the effectiveness of a school-centered primary and secondary prevention program on the prevalence of latent rheumatic heart disease among schoolchildren in Nepal, and to investigate the role…
- Trial name
- NEPAL4 (NCT05504928)
- Testing
- School nurse program
- Where
- Nepal
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Rheumatic Heart Disease
Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System
The first primary objective of this study is to determine the diagnostic performance (sensitivity and specificity) of primary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation…
- Trial name
- ADD-RHD 2B (NCT05668611)
- Testing
- Primary Training Phase, Primary Assessment Phase, Primary Screening Phase
- Where
- Uganda
- Volunteers
- 1,628 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Knee Osteoarthritis
Heart Rate Variability Guided Physical Activity and Exercise Prescription in Individuals With Knee Osteoarthritis
The aim of this trial is to conduct a 12-week randomised controlled trial comparing an HRV-guided home exercise program with traditional home exercise program for individuals with knee osteoarthritis (KOA), followed by 24-week…
- Trial name
- HOPE-OA (NCT07391449)
- Testing
- HRV-guided home exercise prescription, Traditional Home Exercise
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The Hong Kong Polytechnic University