Clinical trials: Rheumatoid Arthritis (RA)
Rheumatoid Arthritis
PK, PD, Safety, and Efficacy of SAIT101 Versus MabThera® Versus Rituxan® in Patients With Rheumatoid Arthritis
A randomised, double blind, parallel group, multicentre study yo compare the pharmacokinetics, pharmacokinetics, safety and efficacy of SAIT101 versus MabThera® versus Rituxan® in patients with rheumatoid arthritis.
- Trial name
- NCT02819726
- Testing
- SAIT101, MabThera, Rituxan
- Where
- 75 sites in United States, Bosnia and Herzegovina and 9 more
- Volunteers
- 294 people
- Sponsor
- Archigen Biotech Limited
Knee Osteoarthritis, Rheumatoid Arthritis (RA)
Comparative Study on the Medium- and Long-term Benefits of Prosthesis Selection in Total Knee Arthroplasty
This retrospective real-world study aims to compare the medium- and long-term clinical outcomes, safety, and economic benefits of different knee prosthesis brands used in primary unilateral total knee arthroplasty (TKA) at our…
- Trial name
- NCT07553871
- Volunteers
- 3,500 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Rheumatoid Arthritis (RA)
National Cohort of Subjects at Risk of Developing Rheumatoid Arthritis
PROMESS 1 is a multicenter cohort interventional study aiming at analyzing the factors associated with the risk of developing clinical arthritis among exposures or combinations of exposures in patients at risk of rheumatoid…
- Trial name
- PROMESS_1 (NCT06876064)
- Testing
- Blood test, Urine test, stool collection
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis Associated Interstitial Lung Disease
Treatment Strategy for Patients With RA-ILD
This is a 52-week, multicenter, prospective, open-label, randomized controlled clinical study, comparing the efficacy and safety of tocilizumab, rituximab, and csDMARD methotrexate in patients with RA-ILD.
- Trial name
- NCT07643038
- Testing
- Tocilizumab, Rituximab (RTX), Methotrexate
- Where
- 22 sites in China
- Volunteers
- 204 people
- Sponsor
- Chinese SLE Treatment And Research Group
Rheumatoid Arthritis (RA)
Use of Acthar in Rheumatoid Arthritis (RA) Related Flares
This is a Rheumatoid Arthritis (RA) study. The purpose of this research study is to determine in RA flare, whether musculoskeletal ultrasound (MSUS) inflammatory scores and/or disease activity scores improve with Acthar treatment.
- Trial name
- NCT02541955
- Testing
- Acthar
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Veena Ranganath, MD, MS
Rheumatoid Arthritis (RA)
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)
Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function.
- Trial name
- NCT04888585
- Testing
- ABBV-154
- Where
- 220 sites in United States, Australia and 19 more
- Volunteers
- 473 people
- Sponsor
- AbbVie
Rheumatoid Arthritis (RA), Rheumatoid Arthritis-Associated Interstitial Lung Disease
Clinical Cohort Construction and Therapeutic Effect Evaluation of Integrated Traditional Chinese and Western Medicine in the Treatment of Rheumatoid Arthritis
This is a large-scale, multicenter observational study on the treatment of rheumatoid arthritis (RA) with integrated Traditional Chinese and Western medicine.
- Conditions
- Rheumatoid Arthritis (RA), Rheumatoid Arthritis-Associated Interstitial Lung Disease, Difficult-to-Treat Rheumatoid Arthritis
- Trial name
- NCT07484243
- Testing
- Integrated Traditional Chinese and Western Medicine
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Dongyi He
Rheumatoid Arthritis
Clinical Outcomes, Compliance and Effectiveness of Switching From Infliximab or Etanercept to Adalimumab in Patients With Active Rheumatoid Arthritis (RA). A Multicenter Post-Marketing Observational Study in Routine Clinical Use
This is a prospective, single-arm, post marketing observational study in adult patients with active rheumatoid arthritis (RA) who are discontinuing treatment due to lack of efficacy, intolerance or to an incomplete response with…
- Trial name
- FALLA (NCT01083160)
- Where
- 12 sites in Mexico
- Volunteers
- 82 people
- Sponsor
- Abbott
Rheumatic Diseases, Rheumatoid Arthritis (RA)
Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis
In the context of this randomized controlled study, patients who are diagnosed with Rheumatoid arthritis in Cerrahpaşa Faculty of Medicine Hospital, will be taken into a rehabilitation program by a qualified physiotherapist to…
- Trial name
- NCT07274124
- Testing
- Pain Neuroscience Education, Vagal Nerve Stimulation, Structured Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Medipol University
Rheumatoid Arthritis
Cost Utility Analyses of Adalimumab Treatment in Patients With Rheumatoid Arthritis (RA)
Evaluation of Health Related Quality of Life (HRQL) is of a paramount importance in assessing the impact of rheumatoid arthritis on patients' health status, however when costs associated with rheumatoid arthritis are also taken…
- Trial name
- HEOR (NCT01078116)
- Where
- 10 sites in Greece
- Volunteers
- 124 people
- Sponsor
- Abbott
Rheumatoid Arthritis
Comparison of Tc 99m Tilmanocept Imaging With IHC Analysis of CD206 Expression in Synovial Tissue of Subjects With RA
This study is a comparison of quantitative Tc 99m tilmanocept imaging with IHC analysis of CD206 expression in synovial tissue of RA subjects.
- Trial name
- NCT04078191
- Testing
- Tc 99m tilmanocept
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 20 people
- Sponsor
- Navidea Biopharmaceuticals
Rheumatoid Arthritis, Osteopenia or Osteoporosis
To Evaluate the Efficacy and Safety of Amorphous Calcium Carbonate in RA Patient With Osteopenia or Osteoporosis
DensityTM, an amorphous calcium carbonate (ACC) imported by Universal Integrated Corporation, is tried to demonstrate its efficacy and safety in rheumatoid arthritis patient with osteopenia or osteoporosis, compared to…
- Trial name
- NCT05443360
- Testing
- DENSITY™ (Amorphous calcium carbonate, ACC), Crystalized calcium carbonate (CCC)
- Where
- 2 sites in Taiwan
- Volunteers
- 180 people
- Sponsor
- China Medical University Hospital
Rheumatoid Arthritis (RA), Anxiety
Mobile App-Based Yoga and Meditation in Rheumatoid Arthritis
The goal of this single-blind, randomized controlled trial is to evaluate the clinical effectiveness and short-term economic impact of a mobile application-based, personalized yoga and meditation program in adult patients with…
- Conditions
- Rheumatoid Arthritis (RA), Anxiety, Depression Anxiety Disorder, Mobile Health Technology (mHealth)
- Trial name
- NCT07666594
- Testing
- Mobile App-Based Yoga and Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Tugba Civi Karaaslan
Rheumatoid Arthritis
A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)
This will be a Phase II, multi-centre study consisting of 2 parts. Part 1: Clinical Pharmacology Study (drug-drug interaction between AK106-001616 and methotrexate) Part 2: Proof of Concept Study
- Trial name
- NCT00902369
- Testing
- AK106-001616, Active comparator
- Where
- 12 sites in Czechia, Germany and 4 more
- Volunteers
- 130 people
- Sponsor
- Asahi Kasei Therapeutics Corporation
Rheumatoid Arthritis
A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of MTRX1011A in Patients With Rheumatoid Arthritis
This is a Phase I multicenter study that will be conducted in the United States and consists of a double-blind, placebo-controlled, SAD stage, followed by a double-blind, placebo controlled MAD stage.
- Trial name
- NCT00718588
- Testing
- MTRX1011A
- Volunteers
- 66 people
- Sponsor
- Genentech, Inc.
Rheumatoid Arthritis (RA
Effects of Chronic Non-invasive Vagus Nerve Stimulation in an Asplenic Individual Suffering From Rheumatoid Arthritis
The goal of this clinical trial is to learn if chronic self-administrated non-invasive vagus nerve stimulation works to improves the disease activity in a single asplenic patient suffering from rheumatoid arthritis.
- Trial name
- NCT07646470
- Testing
- Trans-auricular vagus nerve stimulation
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Osteoflow Health Clinic
Rheumatoid Arthritis
A Study Exploring the Safety, Tolerability, and Efficacy of a 28 Day Course Followed by an Additional 56 Day Course of Itacitinib in Subjects With Active Rheumatoid Arthritis
This is a study evaluating a 28-day course followed by a 56-day course of itacitinib in patients with active rheumatoid arthritis (RA). The study will evaluate safety and efficacy parameters of itacitinib.
- Trial name
- NCT01626573
- Testing
- Itacitinib
- Where
- 18 sites in United States, Puerto Rico
- Volunteers
- 106 people
- Sponsor
- Incyte Corporation
Rheumatoid Arthritis
A Study to Evaluate the Safety and Efficacy of VIB4920 in Participants With Rheumatoid Arthritis
The purpose of the study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of VIB4920 (formerly MEDI4920) in adult participants with rheumatoid arthritis (RA).
- Trial name
- MIDORA (NCT04163991)
- Testing
- VIB4920
- Where
- 25 sites in United States, Poland
- Volunteers
- 78 people
- Sponsor
- Amgen
Arthritis, Rheumatoid
Study to Evaluate SC Route of Administration of Ofatumumab in RA Patients
This study will examine the safety and tolerability, PK and PD of subcutaneously administered GSK1841157 in patients with RA on stable dose Methotrexate.
- Trial name
- NCT00686868
- Testing
- ofatumumab
- Where
- 17 sites in United States, Australia and 7 more
- Volunteers
- 35 people
- Sponsor
- GlaxoSmithKline
Rheumatoid Arthritis, Interstitial Lung Disease
Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease
A study to identify patients with Rheumatoid Arthritis - Associated Interstitial Lung Disease (RA-ILD) that are at the highest risk for progression.
- Trial name
- MOUNTAIN (NCT06397677)
- Testing
- Research Testing Performed (Laboratory), Information Collected as Standard of Care, Research Testing Performed
- Where
- 4 sites in United States
- Volunteers
- 450 people
- Sponsor
- University of Colorado, Denver