Clinical trials: Rhino-conjunctivitis
Hypersensitivity, Immediate, Allergy
Tromsø Birch Rust Allergy Study. Allergy to Birch Rust, a Possible Explanation to Seasonal Airway Allergy During Autumn?
In this project we study if spores from birch rust fungi (Melampsoridium Betulinum = MB) may be the eliciting allergen in patients with seasonal airway allergy during autumn in North Norway.
- Trial name
- Tro-BRA (NCT04322838)
- Testing
- MeDALL questionnaire for allergic diseases, Registration of allergic symptoms, Skin Prick Test
- Where
- Norway
- Volunteers
- 48 people
- Sponsor
- University Hospital of North Norway
Rhino-conjunctivitis
Comparison of Different Up-dosing Schedules With Osiris Phleum Pratense
The purpose of this trial is to investigate the tolerability of Osiris Phleum pratense used with 2 simplified up-dosing schedules compared to the up-dosing schedule used in current practice.
- Trial name
- Osiris (NCT01425788)
- Testing
- Osiris Phleum pratense
- Where
- Poland
- Volunteers
- 236 people
- Sponsor
- ALK-Abelló A/S
Allergic Conditions
Efficacy and Safety of LAIS® Mites Sublingual Tablets
Evaluation of the efficacy and safety of SLIT with LAIS® Mites Sublingual tablets compared to standard drug treatment in patients aged over 60 years suffering from house dust mite (HDM) induced allergic rhino-conjunctivitis…
- Trial name
- korLAIS (NCT02277483)
- Testing
- LAIS®
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Ajou University School of Medicine
Hypersensitivity, Asthma
Quality of Life and Health Economic Measurements in Allergic Patients Treated With Immunotherapy
Grass pollen and house dust mites (HDM) are the most common allergens causing allergic rhino-conjunctivitis (RC) and/or asthma (A). Subcutaneous allergen specific immunotherapy (SCIT) reduces symptoms and use of medication.
- Conditions
- Hypersensitivity, Asthma, Rhino-Conjunctivitis, Quality of Life
- Trial name
- SABAL (NCT01486498)
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Allergic Rhino-Conjunctivitis, Urticaria
To Compare and Evaluate the Oral Bioavailability of Bilastine 20 mg Orally Dispersible Tablet With That of Bilaxten (Bilastine) 20 mg Orally Dispersible Tablet in Healthy, Adult, Human Subjects Under Fasting Conditions
An open label, balanced, randomized single-dose, two-treatment, two sequence, four-period, Full Replicate, crossover oral bioequivalence study in healthy, adult, human subjects under fasting condition.
- Trial name
- NCT07042828
- Testing
- Bilastine oral dispersible tablets, Bilaxten oral dispersible tablets
- Where
- India
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Seasonal Allergic Rhinitis, Hay Fever
Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic Treatment of SAR
Evaluate the relative efficacy of four dosing regimens of bilastine tablets (given either once or twice per day) versus placebo in patients with Seasonal Allergic Rhinitis (SAR) in the Mountain Cedar season in south Texas and…
- Conditions
- Seasonal Allergic Rhinitis, Hay Fever, Allergic Conjunctivitis, Hypersensitivity
- Trial name
- NCT00574379
- Testing
- Bilastine
- Where
- 13 sites in United States
- Volunteers
- 805 people
- Sponsor
- Faes Farma, S.A.
Allergic Rhino-Conjunctivitis
Compare Dose Regimens of AllerT, in Adults With Allergic Rhino-Conjunctivitis to Birch Pollen Studied in EEC
The purpose of this study is to find the optimal dose of AllerT that should be used to treat moderate to severe allergies due to birch tree pollen.
- Trial name
- NCT02271009
- Testing
- AllerT
- Where
- Canada
- Volunteers
- 213 people
- Sponsor
- Anergis
Birch Pollen Allergy, Allergic Rhinoconjunctivitis
S.C. Immunotherapy With BM41 in Patients With Allergic Rhino-conjunctivitis Caused by Birch Pollen
The aim of this clinical phase I single centre, randomized, double-blind, placebo-controlled study with open comparator is to investigate tolerability and safety as well as the immunological effects of BM41 in comparison to…
- Trial name
- BM41 (NCT04912076)
- Testing
- BM41, ALK Alutard SQ Betula verrucosa
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital
Hypersensitivity, Immediate
Norwegian Birch Rust Allergy Study
This study investigates whether spores from birch rust fungi (Melampsoridium Betulinum = MB) may be the eliciting allergen in patients with seasonal airway allergy during autumn in North Norway.
- Trial name
- Nor-BRA (NCT05661812)
- Testing
- Quationnaires and symptom registration, PNIF and spirometry, SPT, spesific IgE, pBAT and NPT
- Where
- Norway
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Perennial Allergic Rhinoconjunctivitis, Allergic Asthma
Effect of an Allergen Vaccine in Patients With Allergic Rhino-Conjunctivitis and Asthma Due to House Dust Mite Allergy
The purpose of the study is to test the safety, tolerability, immunogenicity and clinical efficacy of the combination treatment AllQbG10 in patients with rhino-conjunctivitis and asthma due to house dust mite allergy in a…
- Trial name
- NCT00652223
- Testing
- CYT005-AllQbG10
- Where
- Switzerland
- Volunteers
- 21 people
- Sponsor
- Cytos Biotechnology AG
Hypersensitivity
DBPC-Dose-finding-trial of Vitamin D3 for SCIT in Birch Pollen Allergic Patients.
Low Vitamin D3 (VD3) levels have been reported to be associated with the risk of allergic diseases like asthma. VD3 has been demonstrated in vitro, ex vivo and in animal models to program the immune system towards…
- Trial name
- BM4SIT (NCT02686827)
- Testing
- Paricalcitol
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Laurian Jongejan