Clinical trials: Rhinoplasty
Rhinoplasty, Pain Management
Efficacy of Liposomal Bupivacaine Post Septorhinoplasty
The objective of this study is to determine if there is a difference in post-operative pain after septorhinoplasty when long-acting liposomal bupivacaine is used for local anesthesia compared to other standard local anesthetic…
- Trial name
- NCT05964868
- Testing
- Liposomal Bupivacaine, 0.25% bupivacaine with 1:200,000 epinephrine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Jessyka Lighthall
Subjects Requesting and Requiring an Open Rhinoplasty
A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty
Rhinoplasty (nasal reconstruction i.e. "a nose job") is a surgical procedure performed on the nose to correct a medical problem or change the appearance of the nose.
- Trial name
- NCT01684020
- Testing
- ARTISS human fibrin sealant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- DeNova Research
Wound Healing
Arnica Montana and Bromelain in Rhinoplasty
The purpose of this study is to assess the perioperative use of Arnica Montana and the combined use of Arnica Montana and Bromelain in aiding the body's wound healing functions during the postoperative period after rhinoplasty.
- Trial name
- NCT03586232
- Testing
- Arnica Montana, Bromelain
- Where
- United States
- Sponsor
- Boston Medical Center
Nasal Valve Incompetence, Alar Collapse
Measurement of Age and Sex Related Changes in Nasal Tip Support Using Digital Newton Meter
Background: It is predicted that the nasal tip support will decrease with aging due to weakening of cartilage and connective tissues. However, there is no consensus on the age at which this change began.
- Trial name
- NCT04017923
- Testing
- measurement of nasal tip support in different age groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Postoperative Ecchymosis
DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty
This is study looking at the use of a medication, Desmopressin acetate (DDAVP), to reduce bleeding, swelling, and bruising in patients undergoing cosmetic nose surgery. DDAVP is a drug used in patients with bleeding disorders.
- Trial name
- NCT01982760
- Testing
- DDAVP
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University Hospitals Cleveland Medical Center
Nasal Deformity, Rhinoplasty
Patient-Reported Outcomes and Complications After Structural Rhinoplasty Using Septal Extension Grafts
Structural rhinoplasty with septal extension graft (SEG) is commonly used to achieve stable nasal tip support and predictable long-term outcomes.
- Conditions
- Nasal Deformity, Rhinoplasty, Nasal Obstruction
- Trial name
- SEG-PROM (NCT07531810)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cumhuriyet University Hospital
Fractures
CT Analysis of Structural Buttresses in the Traumatised Nose
Hypothesis: There are 5 support buttresses in the complex osteocartilaginous architecture of the nose. 1. The membranous septum; 2. The Right nasal bone; 3. The Left nasal bone; 4. The perpendicular plate of the ethmoid; 5.
- Trial name
- NCT01136616
- Where
- Singapore
- Volunteers
- 67 people
- Sponsor
- National University Hospital, Singapore
Anesthesia
Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty
To compare the effect of intramuscular dexmedetomidine versus oral gabapentin premedication on the emergence agitation after rhinoplasty.
- Trial name
- NCT05626998
- Testing
- Dexmedetomidine, Gabapentin
- Where
- Egypt
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Sleep Disturbances
Comparison Of The Effects Of Melatonin Premedication And Ketamine On Postoperative Sleep Quality İn Rhinoplasty
Background Postoperative sleep disorders are common complications of surgery and anesthesia that prolong morbidity and hospital stay. Various methods are being explored to prevent and treat these issues.
- Trial name
- NCT06898463
- Testing
- Melatonin (N-acetyl-5-methoxytryptamine), Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Konya City Hospital
Nasal Deformity, Acquired, Septum; Deviation, Congenital
The Evaluation of Piezo and Endonasal Osteotomy Methods on Postoperative Healing Process in Septorhinoplasty
The goal of this observational study is to compare the effect of Piezo and endonasal osteotomy techniques on the healing process of patients undergoing septorhinoplasty surgery.
- Trial name
- NCT06094348
- Testing
- Endonasal osteotomy, Piezo assisted osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Anesthesia, Local
The Effect of Bilateral Infraorbital+ Infratrochlear Nerve Block for Rhinoplasty Operations
The aim of our study is to examine the effect of bilateral infraorbital and infratrochlear nerve blocks for rhinoplasty operations on perioperative remifentanil need and postoperative pain scores.
- Trial name
- NCT05671237
- Testing
- bilateral infraorbital+infratrochlear block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Controlled Hypotension for Nasal Surgeries
Effects of Different MAP Targets on Ocular Perfusion and Optic Nerve Microvasculature During Rhinoplasty
This randomized controlled trial aims to evaluate the effects of two different mean arterial pressure (MAP) targets during controlled hypotension on ocular perfusion and optic nerve head microvasculature in patients undergoing…
- Trial name
- NCT07832305
- Testing
- Lower MAP Target Strategy (50-60 mmHg), Higher MAP Target Strategy (60-70 mmHg)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Rhinoplasty, Dexmedetomidine
Comparison of the Effects of Remifentanil and Dexmedetomidine Administered Under General Anesthesia in Rhinoplasty
The investigators compared the effects of remifentanil and dexmedetomidine administered under general anesthesia on hemodynamics, postoperative pain, recovery, postoperative nausea, vomiting, shivering, patient's and surgeon's…
- Conditions
- Rhinoplasty, Dexmedetomidine, Remifentanil
- Trial name
- NCT05572723
- Testing
- Remifentanil 2 MG, dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University
Rhinoplasty
The Effect of Different Bed Head Heights on Patients After Rhinoplasty
This study will be conducted to evaluate the effect of different bed head heights (thirty degrees and forty-five degrees) given to patients after rhinoplasty surgery on periorbital edema, periorbital ecchymosis, respiratory…
- Trial name
- NCT05695794
- Testing
- the group with a bed head height of 45 degrees, the group with a bed head height of 30 degrees
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Rhinoplasty, Oxidative Stress
Effect of ORI-guided Oxygen Titration on Oxidative Stress in Rhinoplasty Surgery
The aim of this study is to evaluate whether the use of Oxygen Reserve Index (ORİ) can prevent hyperoxia in patients undergoing rhinoplasty surgery and whether it can reduce oxidative stress caused by hyperoxia.
- Conditions
- Rhinoplasty, Oxidative Stress, Hyperoxia, Oxygen Reserve Index
- Trial name
- NCT07158073
- Testing
- FiO₂ titration, under the guidance of ORI, Conventional oxygen administration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Rhinoplasty Techniques
Spreader Graft and Lateral Crural Overlay Technique in Rhinoplasty
Most of the studies performed to compare the present techniques of rhinoplasty have been based on the clinical examination and change of postoperative complaints that cannot be very precise in evaluating the advantages of one…
- Trial name
- NCT01852643
- Testing
- Spreader graft, Lateral crural overlay
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Isfahan University of Medical Sciences
Rhinoplasty Techniques
Hybrid Osteoplasty Versus Osteotomy in Rhinoplasty
This study is designed to compare two common techniques for reducing the nasal hump during rhinoplasty: the traditional method using osteotomes and rasps, and a newer technique called hybrid osteoplasty that uses a surgical…
- Trial name
- NCT07142525
- Testing
- Hybrid Osteoplasty, Traditional Osteotomy and Rasping
- Where
- Iraq
- Volunteers
- 200 people
- Sponsor
- University of Sulaimani
Rhinoplasty, Quality of Life
Rhinoplasty and Quality of Life
Quality of life and satisfaction in aesthetic surgery is still under-evaluated. It is a prospective and multicenter study with a 4 months follow-up of patients under rhinoplasty or rhinoseptoplasty procedure.
- Trial name
- FACE-Q (NCT03519100)
- Testing
- quality of life evaluation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty
Unilateral Septal Extension Graft and Bilateral Septal Extension Graft in Droopy Tip and Its Effect on Tip Deviation
This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation.
- Conditions
- Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty, Nasal Projection
- Trial name
- NCT07446426
- Testing
- Unilateral septal extension graft, Bilateral septal extension graft
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Tanta University
Remimazolam, Emergence Delirium
Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty
The aim of this research is to confirm the effectiveness of remimazolam in preventing delirium during recovery from anesthesia in adult patients who have undergone one of the rhinological surgeries (septoplasty, rhinoseptoplasty…
- Conditions
- Remimazolam, Emergence Delirium, Rhinoplasty
- Trial name
- NCT06398275
- Testing
- Remimazolam 20 MG Injection [Byfavo], NaCl 0.9%
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University Hospital of Split