Clinical trials: Rhinoplasty
Pain, Postoperative, Rhinoplasty
Sphenopalatine Ganglion Block in Septorhinoplasty
Septorhinoplasty is a widely performed surgery that aims to correct both functional and aesthetic problems of the nose. Despite its expected clinical benefits, septorhinoplasty surgery causes postoperative pain, which affects the…
- Trial name
- NCT06157970
- Testing
- Sphenopalatine Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medeniyet University
Pain, Postoperative, Local Anesthetic
The Utility of Long-acting Local Anesthetic Agents in Reducing Post-operative Opioid Requirements Following Rhinoplasty
On average, more than 130 Americans die every day from opioid overdose. Surgeons provide 37% of all opioid prescriptions in the United states, second only behind pain management physicians.
- Trial name
- NCT04377204
- Testing
- marcaine bupivacaine, Lidocaine
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital
Edema, Bruising
Steroids for Rhinoplasty: Pain, Nausea, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of medrol dosepaks (oral corticosteroids) on postoperative outcomes among patients undergoing rhinoplasty by Facial Plastic Surgeons at Vanderbilt.
- Conditions
- Edema, Bruising, Nasal Obstruction, Postoperative Pain
- Trial name
- NCT06483204
- Testing
- Medrol 4 MG Oral Tablet Includes Medrol Dosepak
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cleft Lip, Cleft Palate
Use of Titanium Plate in Rhinoplasty in Patients With Cleft Lip and Palate : Aesthetic and Functional Impact.
The patients in this study are all born with a cleft lip and palate. They underwent several interventions in childhood to take care of it.
- Trial name
- PETROL/TROPHIC (NCT03572907)
- Testing
- Rhinoplasty questionnaire
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Hypotension, Surgery-Complications
The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension
In this study, the effects of nicardipine and esmolol applied for controlled hypotension in rhinoplasty on hemodynamics and regional renal oxygenation will be investigated.
- Conditions
- Hypotension, Surgery-Complications, Oxygen Deficiency
- Trial name
- NCT05430724
- Testing
- Controlled hypotention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Yuzuncu Yil University
Rhinoplasty
The Effect of Ice Cold Mentholated Water Spray After Rhinoplasty
This clinical trial aims to evaluate the effects of a menthol-infused cold water spray on thirst perception, dry mouth, nausea, and physiological parameters in patients after rhinoplasty.
- Trial name
- NCT07233057
- Testing
- Menthol Cool Water Spray, Ice water spray
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Firat University
Rhinoplasty, Edema
Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre
This single-centre, randomized, double-blind, sham-controlled clinical trial evaluates whether preoperative photobiomodulation (PBM) with red and infrared light can reduce early postoperative periorbital edema in patients…
- Trial name
- NCT07033039
- Testing
- Photobiomodulation, Simulation of Photobiomodulation, Standard treatment protocol
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Nasal Obstruction
Medical Rhinoplasty: Evaluation of the Efficacy of Hyaluronic Acid in the Treatment of Internal Nasal Valves.
Nasal obstruction is a possible complication of rhinoplasty surgery. Several causes can explain it: deviation of the nasal septum, appearance of mucosal flanges inside the nasal cavity, but also collapse of the internal valve by…
- Trial name
- Rhinomedifon (NCT05134831)
- Testing
- Rhinomanometry
- Sponsor
- Hospices Civils de Lyon
Nasal Obstruction, Bilateral
Effects of Preservation Rhinoplasty Nasal Valve Angle and Area
The study planned to compare the internal nasal valve angle measurements of patients who underwent preservation rhinoplasty before and after surgery.
- Trial name
- NCT06264089
- Testing
- Preservation Rhinoplasty Nasal Valve Angle and Area
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Sleep Apnea, Obstructive
Virtual Surgery of the Upper Airways
Obstructive sleep apnea (OSA) is a sleep related breathing disorder caused by repetitive collapses of the upper airways resulting in impaired breathing, oxygen desaturation and sleep disturbances.
- Trial name
- VirtuOSA (NCT04829201)
- Testing
- functional septorhinoplasty or oropharyngeal/orthognathic surgery
- Where
- 2 sites in Norway
- Volunteers
- 30 people
- Sponsor
- Norwegian University of Science and Technology
Rhinoplasty, Nasal Surgery
Lateral Crural Steal With Columellar Strut Graft in Primary Open Rhinoplasty
The goal of this clinical trial is to assess the effect of Lateral crural steal with Columellar strut graft done in Primary Open Rhinoplasty and its long-term sustainability on nasal tip projection and nasal tip rotation.
- Conditions
- Rhinoplasty, Nasal Surgery, Aesthetic Outcomes
- Trial name
- LCS/CS (NCT07317947)
- Testing
- Lateral crural steal with columellar strut graft in Primary Open Rhinoplasty
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Kafrelsheikh University
Rhinoplasty, Non-steroidal Ant Inflammatory Drugs
Narcotics vs NSAIDs for Post-operative Analgesia in Outpatient Rhinoplasty
The purpose of this study is to compare the efficacy and safety of oral opiate pain medication vs non-steroidal ant inflammatory drugs (NSAIDs) in the treatment of postoperative rhinoplasty pain.
- Conditions
- Rhinoplasty, Non-steroidal Ant Inflammatory Drugs, Opioid Use
- Trial name
- NCT03457116
- Testing
- Norco, NSAID
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- NYU Langone Health
Nasal Obstruction, Rhinoplasty
Inferior Turbinate Surgery in Rhinoseptoplasty: a Randomized Clinical Trial With Quality of Life Outcomes
The purpose of this study is to determine whether inferior turbinate surgery during rhinoseptoplasty is effective in improving quality of life and acoustic rhinometry outcomes.
- Conditions
- Nasal Obstruction, Rhinoplasty, Rhinoseptoplasty, Turbinate Surgery
- Trial name
- NCT01457638
- Testing
- Inferior turbinate surgery, No iInferior turbinate surgery
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Rhinoplasty
Use of Allograft Cartilage in Cosmetic and Reconstructive Rhinoplasty
This is a single-center, blinded, controlled trial, conducted in healthy adult subjects undergoing a reconstructive or cosmetic rhinoplasty involving the use of cartilaginous graft (either non-irradiated cartilage sheet allograft…
- Trial name
- NCT05566808
- Testing
- Autologous Costal Cartilage Graft, Costal Cartilage Allograft.
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Musculoskeletal Transplant Foundation
Hypotensive Anesthesia
Regional Block of the Nose for Hypotensive Anaesthesia in Septo-rhinoplasty
Septorhinoplasty is a cosmetic surgery that many people are choosing to undergo. It can be done under general anesthesia, twilight anesthesia or regional anesthesia.
- Trial name
- NCT03774693
- Testing
- General anesthesia with fentanyl boluses, Regional block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Plastic Surgery Procedures
Non-surgical Rhinoplasty After Nasal Skin Cancer Reconstruction: Enhancing Aesthetic Outcomes
Reconstruction of the nasal pyramid after skin cancer is a complex surgery, often involving multiple stages. For some patients, the final result may be considered insufficient, affecting their quality of life and leading to…
- Trial name
- NCT07094620
- Testing
- Non-surgical rhinoplasty
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pain, Postoperative
Postoperative Pain Management in Rhinoplasty
The primary purpose of the study is to determine adequacy of postoperative pain control after nasal surgery in patients prescribed Acetaminophen (325mg) + Hydrocodone (5mg) compared to Acetaminophen(325mg) + Ibuprofen (200mg)for…
- Trial name
- NCT03584152
- Testing
- Norco 5Mg-325Mg Tablet, Tylenol 325Mg Caplet, Ibuprofen 200 mg
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Stanford University
Pain, Postoperative, Opioid Use
A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty
Adding a single preoperative dose of gabapentin to the standard pain regimen will reduce postoperative opioid consumption within the first 72 hours in patients undergoing rhinoplasty.
- Trial name
- NCT03498261
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Rhinoplasty
Effect of Systemic Inflammatory Index and Systemic Immune Inflammation Index on Ecchymosis, Bleeding and Edema
Rhinoplasty is a cosmetic surgical procedure that is widely applied today and is characterized by edema in the postoperative period.
- Trial name
- NCT06649370
- Testing
- Hypotensive Drugs and/or Vasoactive Drugs
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Anesthesia; Functional
Evaluation of Oxygenation Parameters in Patients Undergoing Rhinoplasty Under General Anesthesia
The investigators are planning to compare the oxygenation values (Pao2/fio2, lactate etc.) in patients who underwent TCI and inhalation anesthesia in rhinoplasty operation.
- Trial name
- NCT05754515
- Testing
- target controlled infusion (TCI) group
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Duzce University