Clinical trials: Rhythm
Sleepiness, Daytime, Fatigue
Lifestyle Medicine Strategies for Combating Sleepiness and Fatigue in Professional Drivers
Sleep has a number of health benefits, including memory and learning, vitality and energy as well as high quality of life levels.
- Conditions
- Sleepiness, Daytime, Fatigue, Sleep Disorders, Circadian Rhythm
- Trial name
- HighWay2Health (NCT05096130)
- Testing
- Lifestyle Medicine Strategies
- Where
- Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Thessaly
Healthy
A Study in Healthy People to Test Whether Different Doses of BI 1015550 Have Potential to Induce Heart Rhythm Abnormalities
The main objective of this trial is to evaluate the effects of a single therapeutic and a single supra-therapeutic dose of BI 1015550 following oral administration on cardiac safety parameters in healthy male and female…
- Trial name
- NCT06107036
- Testing
- BI 1015550, Moxifloxacin
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Sleep, Circadian Rhythm Disorders
Sleep Timing, Eating and Activity Measurement Study
There is strong reason to believe that sleep promotion during adolescence could yield long-term health rewards; the investigators' data show that, when they get more sleep, Morning Larks have impressively reduced intake of…
- Conditions
- Sleep, Circadian Rhythm Disorders, Dietary Habits
- Trial name
- STEAM (NCT04992611)
- Testing
- Sleep Extension (Early), Sleep Extension (Late)
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Breastfeeding, Bottle Feeding
The Effect of Oral Feeding Model With a Chronobiological Approach in Preterm Infants
As in healthy term babies, the ideal food for preterm infants and sick term babies is breast milk. There are many studies indicating that the composition of breast milk can vary from mother to mother, according to the gestational…
- Conditions
- Breastfeeding, Bottle Feeding, Preterm, Chronobiology Disorders
- Trial name
- NCT04992819
- Testing
- Chronobiological Approach Nutrition Model
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Okan University
Persistent Atrial Fibrillation
Utilizing Novel Dipole Density Capabilities to Objectively Visualize the Etiology of Rhythms in Atrial Fibrillation
A prospective, single-arm, multi-center, multi-national, non-randomized, post-market study designed to provide clinical data regarding the use of the AcQMap™ System in the ablation of persistent atrial fibrillation.
- Trial name
- UNCOVER-AF (NCT02825992)
- Testing
- AcQMap System
- Where
- 12 sites in Canada, Czechia and 4 more
- Volunteers
- 129 people
- Sponsor
- Acutus Medical
Hypertension, Eating Behaviors
Early Time-Restricted Eating in Older Adults With Hypertension
The purpose of this study is to find out how early time-restricted eating affects body rhythms and improves cardiometabolic health in older adults.
- Trial name
- NCT07135505
- Testing
- Early time-restricted eating
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Bipolar Disorder, Bipolar I Disorder
The Effect of Interpersonal Relationships and Social Rhythm Therapy Individuals With Bipolar Disorder
Interpersonal and Social Rhythm Therapy (IPSRT) is a type of psychotherapy that applies social rhythm theories in bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- IPSRT (NCT05420792)
- Testing
- Peplau Interpersonal Relations based IPSRT will be applied to the intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ege University
Lung Adenocarcinoma, Sleep Disorders, Circadian Rhythm
Sleep State in Lung Cancer: A Retrospective Analysis
Lung cancer remains the leading cause of cancer-related mortality globally, with tumor progression closely linked to the immune microenvironment.
- Trial name
- NCT06953492
- Testing
- PSQI
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Parkinson's Disease
Bright Light Therapy for Non-motor Symptoms in Parkinson's Disease
Disruption of sleep and alertness is one of the most disabling non-motor symptoms of Parkinson's disease (PD). Mechanisms leading to impaired sleep and alertness in PD are not well understood, and treatment options remain…
- Trial name
- NCT02909192
- Testing
- Light Therapy Device
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital
Obesity
The Effect of Circadian Timing Program on Obesity Management and Sleep Quality
This study, it was aimed to examine the effect of circadian timing program created for obese individuals with evening chronotype on obesity management and sleep quality.
- Trial name
- NCT04665336
- Testing
- Circadian Timing Program, Sleep Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Kocaeli University
Aging
The Fuel and Rhythm (FAR) Phase 2 Study
Both fuel metabolism and circadian rhythms have emerged as important targets to improve cellular and mitochondrial health and ultimately affect function in older adults.
- Trial name
- NCT05482711
- Testing
- Time Restricted Eating Intervention
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Florida
Respiratory Rhythm Disorder
The Effect of Active Breathing Exercises in Stroke Patients With Respiratory Rhythm Disorder
The goal of this clinical trial is to explore The Effect of Active Breathing Exercises in Stroke Patients With Respiratory Rhythm Disorder.
- Trial name
- ABE-S (NCT06265818)
- Testing
- Rehabilitation training, Active Breathing Exercises
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Zeng Changhao
Thyroid Cancer, Breast Cancer
The Incidence of Breast and Other Cancers Among Female Flight Attendants
Flight attendants may be at an increased risk of breast and other cancers due to work-place exposures including cosmic radiation and circadian rhythm disruption form traveling across multiple time zones.
- Conditions
- Thyroid Cancer, Breast Cancer, Non-Melanoma Skin Cancer, Melanoma
- Trial name
- NCT00342407
- Where
- United States
- Volunteers
- 6,093 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Sleep, HIV Infections
Ai Youmian (Love Better Sleep) for People Living With HIV
People living with HIV (PLWH) frequently report sleep disturbances. The social rhythm theory, which proposes that stressful life events can interfere with sleep by disrupting the stability of daily routines, provides new insights…
- Trial name
- NCT05576844
- Testing
- 8-week interpersonal and social rhythm intervention, Usual care
- Where
- China
- Volunteers
- 113 people
- Sponsor
- Central South University
Smith Magenis Syndrome
Observational Study to Investigate the Melatonin and Cortisol Circadian Rhythms of Individuals With Smith-Magenis Syndrome (SMS)
The purpose of this study is to characterize the circadian rhythm disruption experienced by patients as determined by plasma melatonin, cortisol, and other circadian analytes
- Trial name
- NCT02180451
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vanda Pharmaceuticals
Atrial Fibrillation (AF), Atrial Fibrillation (Prevention of Stroke)
Responding to AF: Pill-in-Pocket Anticoagulation Guided by Automated Monitoring and Alerts
Atrial Fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting 1-2 million people in the UK. AF is characterised by uncoordinated electrical activation and ineffective contraction of the upper cardiac…
- Trial name
- RESPOND-AF (NCT06922695)
- Testing
- Pill-in-pocket anticoagulation
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Oxford University Hospitals NHS Trust
Sleep Disorders, Circadian Rhythm
Actigraphic Measurement of a Neurosurgical Procedure
The study examines and illustrates the utility of utilizing actigraphic measurements to assess treatment response.
- Conditions
- Sleep Disorders, Circadian Rhythm, Pain, Rehabilitation
- Trial name
- NCT00945230
- Testing
- Re-section of a large left anterior cranial fossa meningioma
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Child Psychopharmacology Institute
Cardiac Event
PREVENT - Prospective Rhythm Event Surveillance in the ER With NetGuard
The purpose of this study is to determine the incidence of clinically significant rhythm and rate changes in ED patients who are not placed on conventional telemetry, and to test the user-friendliness of a automated clinician…
- Trial name
- PREVENT (NCT00750958)
- Testing
- NetGuard Automated Clinician Alert System
- Where
- 2 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Datascope Patient Monitoring
Atrial Fibrillation, Atrial Fibrillation Recurrent
DIGITal mOnitoring afTer Af abLation
Recurrence of atrial fibrillation (AF) after a pulmonary vein isolation (PVI) procedure is frequent. Current follow up with Holter monitoring and electrocardiograms (ECG) during outpatient clinic consultations cover only short…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Recurrent, PVI
- Trial name
- DIGITOTAL (NCT05486364)
- Testing
- Digital Monitoring, Standard of care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Ziekenhuis Oost-Limburg
Major Depressive Disorder, Bipolar 1 Disorder
Efficacy of the Mobile Application for Prediction and Prevention of Mood Episode Recurrence Based on Machine Learning
This study was designed to evaluate the efficacy of the mobile application named Circadian Rhythm for Mood (CRM), which was developed to prevent recurring episodes of mood disorders (major depressive disorders, bipolar disorders…
- Conditions
- Major Depressive Disorder, Bipolar 1 Disorder, Bipolar II Disorder
- Trial name
- NCT05400785
- Testing
- Circadian Rhythms for Mood (CRM) application - Active
- Where
- South Korea
- Volunteers
- 93 people
- Sponsor
- Hucircadian
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