Clinical trials: Rhytidoplasty
Skin Aging, Facial Asymmetry
Comparison of an Office-based Limited Facelift and Hospital-based Full Facelift
To compare safety, patient satisfaction, and technical correction between a limited and full facelift, patients meeting strict clinical and safety criteria for both types of facelift will be randomly assigned to have one of these…
- Conditions
- Skin Aging, Facial Asymmetry, Aging Problems
- Trial name
- COAL2 (NCT05419609)
- Testing
- Limited facelift, Full facelift, FACE-Q | Aesthetics - Satisfaction With Lower Face and Jawline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dufresne, Craig, MD, PC
Facelift
Evaluation of Safety and Efficacy of the Apollo™ System for Treatment of Wrinkles and Rhytides
Non-invasive, energy-based, aesthetic treatments are becoming increasingly popular among female and male patients of all ages. Different technologies are presently available to rejuvenate skin, including therapeutic ultrasound…
- Trial name
- NCT01283711
- Testing
- apollo device
- Where
- 2 sites in United States, Israel
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pollogen
Edema Face
Tacrolimus for Malar Edema
Elective lower eyelid surgery is a common cosmetic procedure. Facial swelling is a common complication. Studies suggest that this facial swelling is part of a complex inflammatory process.
- Trial name
- NCT03715387
- Testing
- Tacrolimus Topical 0.1% Topical Ointment, Polysporin Ointment
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Wrinkles, Anti Aging
PER-SAF_PDOS (Performance and Safety of Polydioxanone Suture)
This clinical investigation aims to confirm the safety and efficacy of the ID in facial soft tissue reconstruction, specifically for non-incision surgery to tighten and lift the facial skin for a rejuvenated facial appearance.
- Conditions
- Wrinkles, Anti Aging, Face-lift
- Trial name
- PER-SAF_PDOS (NCT07068061)
- Testing
- PDO suture
- Volunteers
- 50 people
- Sponsor
- 21 Century Medical Co., Ltd.
Tissue Adhesion
Poly-4-Hydroxybutyrate Scaffold in Rhytidectomy
The study is being conducted to objectively assess tissue changes following the use of P4HB in rhytidectomy to understand how the utilization of the surgical mesh may affect tissue mechanical strength and elasticity, wound…
- Trial name
- NCT07132892
- Testing
- Galaflex Lite Scaffold
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jeffrey M. Kenkel
Facelift Surgery, Fat Grafting
Ultrasound-Assessed Facial Macrofat Retention After Facelift
Facelift surgery repositions facial soft tissues but does not by itself restore all age-related volume loss. Autologous macrofat can be placed during the same operation to restore volume, yet the amount of grafted tissue that…
- Trial name
- NCT07805889
- Testing
- Facelift plus facial fat grafting
- Where
- Colombia
- Volunteers
- 400 people
- Sponsor
- Research Inc
Burn of Face, Head and/or Neck, Peeling
Histological Skin Changes of Different Peeling Agents in Surgically Subcutaneous Undermined Skin
The purpose of this study is to examine the histological skin changes induced by different peeling agents (Trichloroacetic acid 25% and 40% and phenol/croton oil) in subcutaneous undermined facial skin flaps.
- Trial name
- NCT02848209
- Testing
- TCA 20% Peeling, Phenol/croton oil Peeling, TCA 40% Peeling
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Aging, Premature Aging
Dissector Assisted Malar Elevation for Rhytidoplasty
BACKGROUND: Endoscopy was first used in plastic surgery for the treatment of frontal rhytides. This minimally invasive approach allows the treatment of frontal wrinkles using a practical procedure that does not directly interfere…
- Trial name
- DAME (NCT00925158)
- Testing
- Dissector Assisted Malar Elevation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
SMG Resection in Comparison to Endoscopic SMG Resection
A Prospective Comparison of Robotic and Endoscopic SMG Resection Via Retroauricular Approach
Traditional transcervical incision of the upper neck is a safe and effective approach for resection of the submandibular gland (SMG).
- Trial name
- NCT01726907
- Testing
- Robotic SMG resection, Endoscopic SMG resection
- Where
- South Korea
- Sponsor
- Yonsei University
Facial Rhytidectomy (Face-lift)
Efficacy and Safety Study of Fibrin Sealant With 4 IU/mL Thrombin, Vapor Heated, Solvent Detergent Treated (FS VH S/D 4) in Face-Lift Procedures
The primary objective of this study is to evaluate the efficacy and safety of fibrin sealant with 4 IU/mL thrombin, vapor heated, solvent detergent treated (FS VH S/D 4) when used to reduce early postoperative bruising in…
- Trial name
- NCT00708071
- Testing
- Fibrin Sealant with 4 IU/ml Thrombin, Vapor-Heated, Solvent Detergent Treated Containing Synthetic Aprotinin (FS VH S/D 4)
- Where
- 6 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Use of the Vloc Suture, Elevation of the Mid-face
Use of V-Loc Suture for Mid-face Lifting in Short-flap Rhytidectomy
This study will evaluate and measure the Vloc suture's ability to elevate the mid-face when using a short flap, short incision technique in during a traditional face-lift.
- Trial name
- NCT02023307
- Testing
- V-Loc Suture
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lifestyle Lift
Surgical Scar, Breast Augmentation
Treatment of Surgical Scars Following Breast Augmentation, Abdominoplasty or Face Lift
Evaluator-blinded study of the safety and performance of fractional radiofrequency (FRF) for the treatment of surgical scars following breast augmentation, abdominoplasty or facelift.
- Conditions
- Surgical Scar, Breast Augmentation, Abdominoplasty, Face Lift
- Trial name
- NCT03467724
- Testing
- Fractional Radiofrequency (FRF)
- Where
- Spain
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Hemophilia, Hemorrhage
Topical and Local TXA in Facelifts - A Randomized Controlled Double Blinded Study
Tranexamic acid (TXA) is a fibrinolytic inhibitor which prevents prolonged bleeding by interfering with fibrin clot breakdown by competitively binding to lysine receptors on plasminogen; this prevents the conversion of…
- Conditions
- Hemophilia, Hemorrhage, Facelift Surgery
- Trial name
- NCT06345833
- Testing
- 1%Tranexamic acid with standard local, 3% TXA, 1% TXA with local plus 3% TXA-soaked pledgets
- Where
- United States
- Sponsor
- University of Minnesota
Skin Laxity, Tissue Degeneration
Histological Evaluation of Human Skin Bx to Assess the Effects of APR Tx as an Adjunct Procedure in Facelift Surgery
The goal of this prospective, single-arm clinical study is to gather quantifiable data on Renuvion's impact on skin elasticity and hydration, indicators of skin quality and estimate the biological skin age using DNA methylation…
- Conditions
- Skin Laxity, Tissue Degeneration, Tissue Breakdown, Collagen Degeneration
- Trial name
- NCT06243744
- Testing
- Renuvion APR System
- Where
- 2 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Bleeding, Bruising Face
Intravenous Tranexamic Acid During Rhytidectomy
This is a prospective, randomized, double-blind study investigating whether intravenous tranexamic acid has any effect on rhytidectomy surgery, or the subsequent postoperative sequelae.
- Conditions
- Bleeding, Bruising Face, Swelling Lips & Face
- Trial name
- NCT03970213
- Testing
- Tranexamic Acid 100Mg/Ml Inj Vil 10Ml, Normal Saline 0.9% Infusion Solution Bag
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Glasgold Group Plastic Surgery
Rhytidoplasty
Anesthetics in Rhytidoplasty - A Comparison Study
This study is a prospective, double-blind, randomized comparison study of different anesthesia methods in rhytidoplasty surgery.
- Trial name
- NCT02410460
- Testing
- clonidine, glycopyrrolate, propofol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mercy Facial Plastic Surgery Center
Brow Ptosis
Photographic Assessment of Eyebrow Position and Range of Motion
Forehead and eyebrow surgery is a frequently performed cosmetic surgical procedure in which the eyebrows are raised to a more aesthetically pleasing position.
- Trial name
- NCT00347308
- Testing
- Eyebrow Position
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Face Lift, Suspension Technique
Thread Lift by Use of Retaining Ligaments
In facial rejuvenating surgery, the current trend calls for fewer and less noticeable scars with desired results. Especially to improve the jowls and nasolabial folds, the thread lift is a simple and inexpensive technique for…
- Conditions
- Face Lift, Suspension Technique, Minimal Invasive Surgery
- Trial name
- TL (NCT02235363)
- Testing
- thread lift
- Where
- South Korea
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Winners Clinic
Face-lift, Facial Rhytidectomy
Efficacy and Safety of FS VH S/D 4 S-apr for Flap Adherence in Rhytidectomy
The purpose of the study is to compare the safety and efficacy of FS VH S/D 4 s-apr versus standard of care in adhering tissue and improving wound healing in subjects undergoing facelift.
- Trial name
- NCT00999141
- Testing
- FS VH S/D 4 s-apr
- Where
- 6 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Skin Laxity
Feasibility Study: Histological Characterization After Treatment With the Ulthera® System
Up to 6 subjects will be enrolled. Subjects who have already chosen to have a surgical facelift procedure will be enrolled. Subjects will receive selective Ulthera® ultrasound exposures in the pre-auricular regions.
- Trial name
- NCT01713569
- Testing
- Ulthera Treatment
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc