Clinical trials: Rickettsia Infections
Leishmaniasis, Leptospirosis
Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne Diseases
Zoonoses and arboviroses refer to a group of diseases transmitted from animals to humans, either directly or indirectly (via mosquitoes, ticks or contact with contaminated environments).
- Conditions
- Leishmaniasis, Leptospirosis, Brucellosis, Q Fever
- Trial name
- SEZAM (NCT06859619)
- Testing
- Peripheral venous blood sample
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Montpellier
TIBOLA, Rickettsia Infections
TIBOLA : Multicenter Descriptive Study in Eastern France
TIBOLA (TIck-BOrne LymphAdenopathy) is a tick-borne disease. The pathogen is most often rickettsia (R. slovaca or R. raoultii), but other strict intracellular bacteria have been described (Francisella tularensis, Coxiella…
- Trial name
- NCT05458245
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Q Fever
Safety Evaluation of a Q-fever Vaccine, NDBR 105
The purpose of this study is to evaluate the safety of Q Fever vaccine, NDBR 105, and collect data on incidence of occupational Q Fever infection in at risk personnel.
- Trial name
- NCT00584454
- Testing
- Q Fever Vaccine (NDBR 105
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Rickettsial Disease
Causes of Fever in Bangladeshi Patients
Background: The clinical features and prevalence of tropical rickettsial illnesses such as murine and scrub typhus in Bangladesh are unknown.
- Trial name
- NCT02339259
- Testing
- Observation
- Where
- Bangladesh
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Compulsive Buying
Memantine Treatment of Compulsive Buying
This is an 8-week, open-labe study of memantine in the treatment of compulsive buying.
- Trial name
- NCT00830375
- Testing
- Memantine
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Tick Borne Encephalitis (TBE), Lyme Borreliosis
FINtick - a Prospective Multicenter Study on Tick-borne Infections in Finland
Ticks in Finland can carry several microbes that may infect humans. The best known tick-borne diseases are Lyme borreliosis and tick-borne encephalitis (TBE).
- Conditions
- Tick Borne Encephalitis (TBE), Lyme Borreliosis, Neoehrlichiosis, Tick-Borne Diseases
- Trial name
- FINtick (NCT07897825)
- Where
- 3 sites in Finland
- Volunteers
- 850 people
- Sponsor
- Turku University Hospital
Rickettsiosis
The Surveillance Clinical Study of Rickettsiosis
The purpose of this surveillance (non-interventional) clinical study is to genotype the causative agents of rickettsioses in biological samples of patients from the regions of Russia.
- Trial name
- NCT06162975
- Where
- 24 sites in Russia
- Volunteers
- 2,000 people
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Infectious Disease, Therapeutics
Rickettsia Clearance Study
Murine typhus is a disease caused by Rickettisa typhi, an obligate intracellular bacterium transmitted by rodent fleas. The disease has a worldwide distribution; however the true burden is unknown, related to its non-specific…
- Trial name
- RiCS (NCT05972772)
- Testing
- Doxycyclin, Azithromycin
- Where
- 2 sites in Laos
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit
Rickettsioses
Laboratory Diagnosis of of Rickettsial and Rickettsia-like Diseases
The low confirmed rickettsioses cases rate may indicate the presence of rickettsiosis other than scrub typhus, murine typhus, and Q fever.
- Trial name
- NCT01137175
- Where
- Taiwan
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Rocky Mountain Spotted Fever
Efficacy of Azithromycin Plus Doxycycline Versus Doxycycline Plus Placebo in Patients With Rocky Mountain Spotted Fever
The aim of this study is to impove the pharmacological treatment of Rocky mountain spotted fever, since is a very ancient disease with an antibiotic therapy that have not changed much the mortality rates, being compared with the…
- Trial name
- Rocky-Z (NCT05398055)
- Testing
- Azithromycin + Doxycycline
- Where
- Mexico
- Volunteers
- 86 people
- Sponsor
- Hospital General de Mexicali
Infection, Rickettsia Infections
Implementation of an RT-PCR Assay for the Diagnosis of Rickettsia Spp. Infection
Rickettsia2024 is a multicenter, tissue observational, retrospective and prospective cohort study. Enrollment will take place within the outpatient clinics of the Infectious Diseases and Dermatology Unit of the IRCCS AOUBO and…
- Trial name
- NCT07307651
- Where
- 2 sites in Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Visceral Leishmaniasis, Human African Trypanosomiasis
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)
Tropical fevers have been a diagnostic challenge from the antiquity. Nowadays, despite the availability of good diagnostic capacities, undifferentiated febrile illnesses continue to be a thorny problem for travel physicians.
- Conditions
- Visceral Leishmaniasis, Human African Trypanosomiasis, Enteric Fever, Melioidosis
- Trial name
- NCT01766830
- Testing
- rk28 ICT, IT LEISH (rK39), Immunochromatographic HAT test
- Where
- 7 sites in Cambodia, Democratic Republic of the Congo and 2 more
- Volunteers
- 1,927 people
- Sponsor
- University Hospital, Geneva
Intellectual Disability, Down Syndrome
Self-Monitoring Shopping Intervention
The purpose of this study is to examine the effectiveness of a self-monitoring intervention to improve shopping performance in adults with intellectual disability (ID) secondary to Down syndrome (DS).
- Trial name
- NCT04020302
- Testing
- Self-monitoring shopping intervention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Columbia University
Fever
Filter Paper Blood Spots Collected During Fever as a Source for Post-travel Diagnosis in Travelers
This study is part of a larger prospective cohort study (JOKA), designed to study febrile illness occurring during a travel to the tropics, as well as the evaluation of the clinical use of malaria rapid diagnostic tests (RDT) by…
- Trial name
- JOKA-II (NCT02900066)
- Where
- Belgium
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Scrub Typhus, Spotted Fever; India
The Epidemiology of Rickettsial Infections in South India: Cohort Study
There is enough evidence to suggest that scrub typhus and spotted fever group rickettsioses are common causes of febrile illness in India. Serological evidence also exists for murine typhus, but is rarely tested for.
- Conditions
- Scrub Typhus, Spotted Fever; India, Murine Typhus
- Trial name
- NCT04506944
- Testing
- No intervention
- Where
- India
- Volunteers
- 32,566 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Sarcoidosis, Rickettsia Infections
Rickettsial Genesis to Sarcoidosis in Denmark
One study has suggested a connection between an infection with Rickettsia species and sarcoidosis finding molecular evidence of rickettsial deoxyribonucleic acid (DNA) in two patients.
- Trial name
- NCT00326534
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Statens Serum Institut